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Ind. Eng. Chem."},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114332_bib92","doi-asserted-by":"crossref","DOI":"10.1021\/cm970421o","article-title":"Biomimetic synthesis and characterization of magnetic proteins (Magnetoferritin)","volume":"10","author":"Wong","year":"1998","journal-title":"Chem. Mater."},{"issue":"12","key":"10.1016\/j.colsurfb.2024.114332_bib93","doi-asserted-by":"crossref","DOI":"10.1002\/sia.1984","article-title":"Investigation of multiplet splitting of Fe 2p XPS spectra and bonding in iron compounds","volume":"36","author":"Grosvenor","year":"2004","journal-title":"Surf. Interface Anal."},{"issue":"9","key":"10.1016\/j.colsurfb.2024.114332_bib94","article-title":"Long-range tunneling processes across ferritin-based junctions","volume":"28","author":"Kumar","year":"2016","journal-title":"Adv. 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Phys."},{"issue":"2","key":"10.1016\/j.colsurfb.2024.114332_bib97","doi-asserted-by":"crossref","DOI":"10.1039\/C6CE02421A","article-title":"Oxidation of magnetite nanoparticles: impact on surface and crystal properties","volume":"19","author":"Schwaminger","year":"2017","journal-title":"CrystEngComm"},{"key":"10.1016\/j.colsurfb.2024.114332_bib98","doi-asserted-by":"crossref","unstructured":"G.S. 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