{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:01:18Z","timestamp":1790787678379,"version":"4.1.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.colsurfb.2024.114436","type":"journal-article","created":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T23:06:27Z","timestamp":1733439987000},"page":"114436","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Different mesoporous carbon carriers for the improvement of solubility and physical stability of poorly soluble drugs"],"prefix":"10.1016","volume":"247","author":[{"given":"Wei","family":"Gu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinfu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanqi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuaipeng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.colsurfb.2024.114436_bib1","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.3390\/biomedicines10092055","article-title":"Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics","volume":"10","author":"Bhalani","year":"2022","journal-title":"Biomedicines"},{"issue":"3","key":"10.1016\/j.colsurfb.2024.114436_bib2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1023\/A:1016212804288","article-title":"A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability","volume":"12","author":"Amidon","year":"1995","journal-title":"Pharm. Res."},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib3","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0939-6411(00)00076-X","article-title":"Improving drug solubility for oral delivery using solid dispersions","volume":"50","author":"Leuner","year":"2000","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"3","key":"10.1016\/j.colsurfb.2024.114436_bib4","doi-asserted-by":"crossref","first-page":"285","DOI":"10.3109\/10837450.2010.535826","article-title":"A biopharmaceutical classification-based Right-First-Time formulation approach to reduce human pharmacokinetic variability and project cycle time from First-In-Human to clinical Proof-Of-Concept","volume":"17","author":"Ku","year":"2012","journal-title":"Pharm. Dev. Technol."},{"key":"10.1016\/j.colsurfb.2024.114436_bib5","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jconrel.2015.09.012","article-title":"Improved oral absorption of exenatide using an original nanoencapsulation and microencapsulation approach","volume":"217","author":"Soudry-Kochavi","year":"2015","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpharm.2011.08.032","article-title":"Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications","volume":"420","author":"Kawabata","year":"2011","journal-title":"Int. J. Pharm."},{"issue":"6","key":"10.1016\/j.colsurfb.2024.114436_bib7","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.addr.2007.08.042","article-title":"Enhancing drug absorption using lipids: a case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the treatment of systemic fungal infections","volume":"60","author":"Kristina","year":"2008","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib8","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1124\/pr.112.005660","article-title":"Strategies to address low drug solubility in discovery and development","volume":"65","author":"Williams","year":"2013","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.colsurfb.2024.114436_bib9","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.2147\/IJN.S38378","article-title":"Nanodrugs: pharmacokinetics and safety","author":"Onoue","year":"2014","journal-title":"Int J. Nanomed. 9"},{"issue":"2","key":"10.1016\/j.colsurfb.2024.114436_bib10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jnoncrysol.2011.09.020","article-title":"Fabrication of mesoporous hydroxycarbonate apatite for oral delivery of poorly water-soluble drug carvedilol","volume":"358","author":"Zhao","year":"2012","journal-title":"J. Non-Cryst. Solids"},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib11","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nrc.2016.108","article-title":"Cancer nanomedicine: progress, challenges and opportunities","volume":"17","author":"Shi","year":"2017","journal-title":"Nat. Rev. Cancer"},{"issue":"4","key":"10.1016\/j.colsurfb.2024.114436_bib12","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1021\/acs.molpharmaceut.5b00903","article-title":"Stabilization of the amorphous ezetimibe drug by confining its dimension","volume":"13","author":"Knapik","year":"2016","journal-title":"Mol. Pharm."},{"issue":"7","key":"10.1016\/j.colsurfb.2024.114436_bib13","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1039\/C3CS60234F","article-title":"Crystallization under nanoscale confinement","volume":"43","author":"Jiang","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.colsurfb.2024.114436_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejps.2022.106132","article-title":"Inhibition of celecoxib crystallization by mesoporous silica \u2013 Molecular dynamics studies leading to the discovery of the stabilization origin","volume":"171","author":"Kramarczyk","year":"2022","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2024.114436_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2020.119492","article-title":"Degrees of order: a comparison of nanocrystal and amorphous solids for poorly soluble drugs","volume":"586","author":"Peltonen","year":"2020","journal-title":"Int. J. Pharm."},{"issue":"8","key":"10.1016\/j.colsurfb.2024.114436_bib16","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.3390\/molecules28083406","article-title":"Mesoporous drug delivery system: from physical properties of drug in solid state to controlled release","volume":"28","author":"Wang","year":"2023","journal-title":"Molecules"},{"issue":"2","key":"10.1016\/j.colsurfb.2024.114436_bib17","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ejps.2005.06.005","article-title":"Preparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying technique","volume":"26","author":"Chauhan","year":"2005","journal-title":"Eur. J. Pharm. Sci."},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ijpharm.2012.04.066","article-title":"Emerging trends in the stabilization of amorphous drugs","volume":"453","author":"Laitinen","year":"2013","journal-title":"Int. J. Pharm."},{"issue":"2","key":"10.1016\/j.colsurfb.2024.114436_bib19","doi-asserted-by":"crossref","first-page":"420","DOI":"10.3109\/10717544.2014.916767","article-title":"The mechanism for increasing the oral bioavailability of poorly water-soluble drugs using uniform mesoporous carbon spheres as a carrier","volume":"23","author":"Wang","year":"2016","journal-title":"Drug Deliv."},{"issue":"9","key":"10.1016\/j.colsurfb.2024.114436_bib20","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1016\/j.xphs.2015.10.008","article-title":"Polymeric amorphous solid dispersions: a review of amorphization, crystallization, stabilization, solid-state characterization, and aqueous solubilization of biopharmaceutical classification system class II drugs","volume":"105","author":"Baghel","year":"2016","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2024.114436_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2021.120637","article-title":"The use of polymer blends to improve stability and performance of electrospun solid dispersions: the role of miscibility and phase separation","volume":"602","author":"Tipduangta","year":"2021","journal-title":"Int. J. Pharm."},{"issue":"16","key":"10.1016\/j.colsurfb.2024.114436_bib22","doi-asserted-by":"crossref","first-page":"9537","DOI":"10.1016\/j.ijhydene.2022.01.048","article-title":"An excellent universal catalyst support-mesoporous silica: preparation, modification and applications in energy-related reactions","volume":"47","author":"Wei","year":"2022","journal-title":"Int. J. Hydrog. Energy"},{"issue":"27","key":"10.1016\/j.colsurfb.2024.114436_bib23","doi-asserted-by":"crossref","first-page":"11580","DOI":"10.1039\/C5NR02389K","article-title":"Synthesis of mesoporous carbon nanoparticles with large and tunable pore sizes","volume":"7","author":"Liu","year":"2015","journal-title":"Nanoscale"},{"issue":"2","key":"10.1016\/j.colsurfb.2024.114436_bib24","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2174\/1381612827666211111152839","article-title":"Recent Developments in Mesoporous Silica Nanoparticles for Tumor Theranostic Applications","volume":"28","author":"Wang","year":"2022","journal-title":"Curr. Pharm. Des."},{"issue":"2","key":"10.1016\/j.colsurfb.2024.114436_bib25","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.nano.2014.09.014","article-title":"Mesoporous silica nanoparticles in drug delivery and biomedical applications","volume":"11","author":"Wang","year":"2015","journal-title":"Nanomed. -Nanotechnol. Biol. Med."},{"issue":"9","key":"10.1016\/j.colsurfb.2024.114436_bib26","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.1039\/C2CS35301F","article-title":"Direct synthesis of ordered mesoporous carbons","volume":"42","author":"Ma","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.colsurfb.2024.114436_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2021.112067","article-title":"Influence of molecular interactions on structure, controlled release and cytotoxicity of curcumin encapsulated chitosan - Silica nanostructured microspheres","volume":"208","author":"Bhatt","year":"2021","journal-title":"Colloids Surf. B: Biointerfaces"},{"key":"10.1016\/j.colsurfb.2024.114436_bib28","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.biomaterials.2015.05.022","article-title":"Co-delivery of hydrophobic paclitaxel and hydrophilic AURKA specific siRNA by redox-sensitive micelles for effective treatment of breast cancer","volume":"61","author":"Yin","year":"2015","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib29","first-page":"1","article-title":"Curcumin loaded Silica Nanoparticles and their therapeutic applications: a review","volume":"7","author":"Pant","year":"2020","journal-title":"J. Mater. Nanosci."},{"issue":"2","key":"10.1016\/j.colsurfb.2024.114436_bib30","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1080\/10717544.2017.1399300","article-title":"Mesoporous carbon nanomaterials in drug delivery and biomedical application","volume":"24","author":"Zhao","year":"2017","journal-title":"Drug Deliv."},{"key":"10.1016\/j.colsurfb.2024.114436_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.134886","article-title":"Advances in smart mesoporous carbon nanoplatforms for photothermal-enhanced synergistic cancer therapy","volume":"435","author":"Feng","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2024.114436_bib32","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jhazmat.2018.08.069","article-title":"Immobilization of laccase on hollow mesoporous carbon nanospheres: noteworthy immobilization, excellent stability and efficacious for antibiotic contaminants removal","volume":"362","author":"Shao","year":"2019","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.colsurfb.2024.114436_bib33","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.jcis.2019.07.005","article-title":"Gold nanoparticles modified hollow carbon system for dual-responsive release and chemo-photothermal synergistic therapy of tumor","volume":"554","author":"Zhao","year":"2019","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.colsurfb.2024.114436_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfa.2023.131450","article-title":"Release kinetics study of fatty acids eutectic mixture gated mesoporous carbon nanoparticles for chemo-photothermal therapy","volume":"669","author":"Lu","year":"2023","journal-title":"Colloids Surf. A: Physicochem. Eng. Asp."},{"key":"10.1016\/j.colsurfb.2024.114436_bib35","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.carbon.2022.07.073","article-title":"Tailored nanoplatforms with detachable 'meteorolite' for photothermal-enhanced programmed tumor therapy","volume":"199","author":"Zhao","year":"2022","journal-title":"Carbon"},{"key":"10.1016\/j.colsurfb.2024.114436_bib36","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jcis.2017.09.088","article-title":"Size effect on oral absorption in polymer-functionalized mesoporous carbon nanoparticles","volume":"511","author":"Ran","year":"2018","journal-title":"J. Colloid Interface Sci."},{"issue":"3","key":"10.1016\/j.colsurfb.2024.114436_bib37","first-page":"1254","article-title":"Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis","volume":"99","year":"2010","journal-title":"J. Pharm."},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib38","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0169-409X(01)00098-9","article-title":"Amorphous pharmaceutical solids: preparation, characterization and stabilization","volume":"48","author":"Yu","year":"2001","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"5","key":"10.1016\/j.colsurfb.2024.114436_bib39","first-page":"1574","article-title":"Solid dispersion technique for improving solubility of some poorly soluble drugs","volume":"4","author":"Mogal","year":"2012","journal-title":"Der Pharm. Lett."},{"issue":"5","key":"10.1016\/j.colsurfb.2024.114436_bib40","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.ejps.2012.01.003","article-title":"Inclusion of celecoxib into fibrous ordered mesoporous carbon for enhanced oral bioavailability and reduced gastric irritancy","volume":"45","author":"Zhao","year":"2012","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2024.114436_bib41","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.msec.2014.02.035","article-title":"Mesoporous carbon with spherical pores as a carrier for celecoxib with needle-like crystallinity: improve dissolution rate and bioavailability","volume":"39","author":"Zhu","year":"2014","journal-title":"Mater. Sci. Eng.: C."},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib42","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.ijpharm.2013.05.016","article-title":"Mesoporous carbon as a novel drug carrier of fenofibrate for enhancement of the dissolution and oral bioavailability","volume":"452","author":"Niu","year":"2013","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2024.114436_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2019.115508","article-title":"Polymer-functionalized mesoporous carbon nanoparticles on overcoming multiple barriers and improving oral bioavailability of Probucol","volume":"229","author":"Lu","year":"2020","journal-title":"Carbohydr. Polym."},{"issue":"1","key":"10.1016\/j.colsurfb.2024.114436_bib44","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ijpharm.2015.02.054","article-title":"Folate-polyethyleneimine functionalized mesoporous carbon nanoparticles for enhancing oral bioavailability of paclitaxel","volume":"484","author":"Wan","year":"2015","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2024.114436_bib45","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.jcis.2017.11.065","article-title":"Effects of surface modification and size on oral drug delivery of mesoporous silica formulation","volume":"513","author":"Wang","year":"2018","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.colsurfb.2024.114436_bib46","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.actbio.2017.10.025","article-title":"Overcoming multiple gastrointestinal barriers by bilayer modified hollow mesoporous silica nanocarriers","volume":"65","author":"Wang","year":"2018","journal-title":"Acta Biomater."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776524006957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776524006957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T20:34:28Z","timestamp":1737318868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776524006957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":46,"alternative-id":["S0927776524006957"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2024.114436","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Different mesoporous carbon carriers for the improvement of solubility and physical stability of poorly soluble drugs","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2024.114436","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114436"}}