{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T23:56:17Z","timestamp":1792540577476,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003172","name":"Henan University of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003172","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22305069"],"award-info":[{"award-number":["22305069"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22306055"],"award-info":[{"award-number":["22306055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.colsurfb.2025.114688","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T22:06:26Z","timestamp":1744149986000},"page":"114688","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["PEGylated PAMAM dendrimer nanoplatform for co-delivery of chemotherapeutic agents and inorganic nanoparticles enhancing chemo-photothermal combination therapy"],"prefix":"10.1016","volume":"252","author":[{"given":"Binzhong","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1844-9431","authenticated-orcid":false,"given":"Qiuli","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leitao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenlan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1566-0306","authenticated-orcid":false,"given":"Junbo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.colsurfb.2025.114688_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e24395","article-title":"Global trends in bufalin application research for cancer from 2003 to 2022: a bibliometric and visualised analysis","volume":"10","author":"Tang","year":"2024","journal-title":"Heliyon"},{"issue":"6","key":"10.1016\/j.colsurfb.2025.114688_bib2","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1039\/C8BM00005K","article-title":"Composite-dissolving microneedle patches for chemotherapy and photothermal therapy in superficial tumor treatment","volume":"6","author":"Pei","year":"2018","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.colsurfb.2025.114688_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2024.113282","article-title":"Unveiling the potential of inorganic nanoarchitecture-mediated photothermal therapy: an illustration on melanoma","volume":"216","author":"Hedaoo","year":"2024","journal-title":"Eur. Polym. J."},{"key":"10.1016\/j.colsurfb.2025.114688_bib4","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jconrel.2024.08.014","article-title":"NIR-triggered and Thermoresponsive Core-shell nanoparticles for synergistic anticancer therapy","volume":"374","author":"Zhang","year":"2024","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2025.114688_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2024.116508","article-title":"Nanomaterials-based advanced systems for photothermal\/photodynamic therapy of oral cancer","volume":"272","author":"Wang","year":"2024","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.colsurfb.2025.114688_bib6","doi-asserted-by":"crossref","first-page":"13193","DOI":"10.1038\/ncomms13193","article-title":"Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy","volume":"7","author":"Chen","year":"2016","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.colsurfb.2025.114688_bib7","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1021\/nn5002112","article-title":"Combinatorial photothermal and immuno cancer therapy using chitosan-coated hollow copper sulfide nanoparticles","volume":"8","author":"Guo","year":"2014","journal-title":"ACS Nano"},{"issue":"48","key":"10.1016\/j.colsurfb.2025.114688_bib8","doi-asserted-by":"crossref","first-page":"8154","DOI":"10.1002\/adma.201402996","article-title":"Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis","volume":"26","author":"Wang","year":"2014","journal-title":"Adv. Mater."},{"issue":"11","key":"10.1016\/j.colsurfb.2025.114688_bib9","doi-asserted-by":"crossref","first-page":"10245","DOI":"10.1021\/acsnano.6b05760","article-title":"Albumin-Bioinspired Gd:CuS nanotheranostic agent for in vivo photoacoustic\/magnetic resonance imaging-guided tumor-targeted photothermal therapy","volume":"10","author":"Yang","year":"2016","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2025.114688_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2024.113282","article-title":"Unveiling the potential of inorganic nanoarchitecture-mediated photothermal therapy: An illustration on melanoma","volume":"216","author":"Hedaoo","year":"2024","journal-title":"Eur. Polym. J."},{"issue":"46","key":"10.1016\/j.colsurfb.2025.114688_bib11","doi-asserted-by":"crossref","first-page":"53273","DOI":"10.1021\/acsami.3c12854","article-title":"Codelivery of CuS and DOX into deep tumors with size and charge-switchable PAMAM dendrimers for chemo\u2013photothermal therapy","volume":"15","author":"Hu","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2025.114688_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2024.114362","article-title":"Precise photothermal treatment of bacterial infection mediated by charge-switchable nanoplatform with acylsulfonamide betaine surface","volume":"245","author":"Sun","year":"2025","journal-title":"Colloids Surf. B: Biointerfaces"},{"issue":"11","key":"10.1016\/j.colsurfb.2025.114688_bib13","doi-asserted-by":"crossref","first-page":"8722","DOI":"10.1039\/C5RA25870G","article-title":"CuS nanocrystal@microgel nanocomposites for light-regulated release of dual-drugs and chemo-photothermal synergistic therapy in vitro","volume":"6","author":"Sun","year":"2016","journal-title":"RSC Adv."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114688_bib14","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1039\/C8BM01412D","article-title":"Paramagnetic CuS hollow nanoflowers for T2-FLAIR magnetic resonance imaging-guided thermochemotherapy of cancer","volume":"7","author":"Zhang","year":"2019","journal-title":"Biomater. Sci."},{"issue":"2","key":"10.1016\/j.colsurfb.2025.114688_bib15","doi-asserted-by":"crossref","first-page":"615","DOI":"10.7150\/thno.40066","article-title":"Supramolecular nanomaterials based on hollow mesoporous drug carriers and macrocycle-capped CuS nanogates for synergistic chemo-photothermal therapy","volume":"10","author":"Yang","year":"2020","journal-title":"Theranostics"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114688_bib16","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s40824-022-00308-z","article-title":"Recent advances in near-infrared-II hollow nanoplatforms for photothermal-based cancer treatment","volume":"26","author":"Zhang","year":"2022","journal-title":"Biomater. Res."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114688_bib17","doi-asserted-by":"crossref","first-page":"4267","DOI":"10.1038\/s41467-024-46533-z","article-title":"An antifouling membrane-fusogenic liposome for effective intracellular delivery in vivo","volume":"15","author":"Kong","year":"2024","journal-title":"Nat. Commun."},{"issue":"32","key":"10.1016\/j.colsurfb.2025.114688_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201902542","article-title":"In situ modification of the tumor cell surface with immunomodulating nanoparticles for effective suppression of tumor growth in mice","volume":"31","author":"Zheng","year":"2019","journal-title":"Adv. Mater."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114688_bib19","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1021\/acs.molpharmaceut.7b00515","article-title":"Pyrrolidone modification prevents PAMAM dendrimers from activation of pro-inflammatory signaling pathways in human monocytes","volume":"15","author":"Janaszewska","year":"2017","journal-title":"Mol. Pharm."},{"issue":"7","key":"10.1016\/j.colsurfb.2025.114688_bib20","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1016\/j.nano.2018.07.005","article-title":"Cytotoxicity and in vivo plasma kinetic behavior of surface-functionalized PAMAM dendrimers","volume":"14","author":"Diaz","year":"2018","journal-title":"Nanomed.: Nanotechnol., Biol. Med."},{"key":"10.1016\/j.colsurfb.2025.114688_bib21","first-page":"332","article-title":"Enhanced biocompatibility of PAMAM dendrimers benefiting from tuning their surface charges","volume":"93","author":"Cui","year":"2018","journal-title":"Biomater. Adv."},{"issue":"6","key":"10.1016\/j.colsurfb.2025.114688_bib22","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.nano.2012.03.009","article-title":"Surface modification of PAMAM dendrimer improves its biocompatibility","volume":"8","author":"Ciolkowski","year":"2012","journal-title":"Nanomed.: Nanotechnol., Biol. Med."},{"issue":"5","key":"10.1016\/j.colsurfb.2025.114688_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/EXP.20220161","article-title":"In vivo synergistic tumor therapies based on copper sulfide photothermal therapeutic nanoplatforms","volume":"3","author":"Ma","year":"2023","journal-title":"Exploration"},{"key":"10.1016\/j.colsurfb.2025.114688_bib24","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0076-6879(99)09028-X","article-title":"Methods for studying protein adsorption","volume":"309","author":"Hlady","year":"1999","journal-title":"Methods Enzymol."},{"issue":"5","key":"10.1016\/j.colsurfb.2025.114688_bib25","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1021\/acs.biomac.9b00494","article-title":"Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug delivery","volume":"20","author":"Wang","year":"2019","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.colsurfb.2025.114688_bib26","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.vibspec.2016.11.001","article-title":"Non-equilibrium behavior of polyethylene glycol (PEG)\/polypropylene glycol (PPG) mixture studied by Fourier transform infrared (FTIR) spectroscopy","volume":"88","author":"Shinzawa","year":"2017","journal-title":"Vib. Spectrosc."},{"issue":"2","key":"10.1016\/j.colsurfb.2025.114688_bib27","first-page":"262","article-title":"ROS-responsive PLGA-NPs for Co-delivery of DTX and DHA for colon cancer treatment","volume":"4","author":"Cassano","year":"2024","journal-title":"Int. J. Transl. Med."},{"issue":"31","key":"10.1016\/j.colsurfb.2025.114688_bib28","doi-asserted-by":"crossref","first-page":"6366","DOI":"10.1039\/C7TB01517H","article-title":"Glutathione-capped, renal clearable CuS nanodots for photoacoustic imaging and photothermal therapy","volume":"5","author":"Liang","year":"2017","journal-title":"J. Mater. Chem. B"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114688_bib29","doi-asserted-by":"crossref","first-page":"4267","DOI":"10.1038\/s41467-024-46533-z","article-title":"An antifouling membrane-fusogenic liposome for effective intracellular delivery in vivo","volume":"15","author":"Kong","year":"2024","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.colsurfb.2025.114688_bib30","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1038\/nrc.2017.93","article-title":"Transport of drugs from blood vessels to tumour tissue","volume":"17","author":"Dewhirst","year":"2017","journal-title":"Nat. Rev. Cancer"},{"issue":"4","key":"10.1016\/j.colsurfb.2025.114688_bib31","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1080\/15548627.2022.2125629","article-title":"The acid gate in the lysosome","volume":"19","author":"Hu","year":"2023","journal-title":"Autophagy"},{"issue":"4","key":"10.1016\/j.colsurfb.2025.114688_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1208\/s12249-021-02000-2","article-title":"Tumor-targeted delivery of bufalin-loaded modified albumin\u2013polymer hybrid for enhanced antitumor therapy and attenuated hemolysis toxicity and cardiotoxicity","volume":"22","author":"Xu","year":"2021","journal-title":"AAPS Pharmscitech"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114688_bib33","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/jbm.b.31558","article-title":"Protective effect of PEGylation against poly(amidoamine) dendrimerinduced hemolysis of human red blood cells","volume":"93","author":"Wang","year":"2010","journal-title":"J. Biomed. Mater. Res. Part B: Appl. Biomater."},{"issue":"10","key":"10.1016\/j.colsurfb.2025.114688_bib34","doi-asserted-by":"crossref","first-page":"5169","DOI":"10.1021\/acsbiomaterials.9b01173","article-title":"Photothermal killing of methicillin-resistant staphylococcus aureus by bacteria-targeted polydopamine nanoparticles with nano-localized hyperpyrexia","volume":"5","author":"Hu","year":"2019","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.colsurfb.2025.114688_bib35","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.jconrel.2024.10.029","article-title":"Tumor therapy utilizing dual-responsive nanoparticles: a multifaceted approach integrating calcium-overload and PTT\/CDT\/chemotherapy","volume":"376","author":"Yang","year":"2024","journal-title":"J. Control. Release"},{"issue":"42","key":"10.1016\/j.colsurfb.2025.114688_bib36","doi-asserted-by":"crossref","first-page":"36606","DOI":"10.1021\/acsami.7b11062","article-title":"Strong near-infrared absorbing and biocompatible CuS nanoparticles for rapid and efficient photothermal ablation of gram-positive and -negative bacteria","volume":"9","author":"Huang","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"29","key":"10.1016\/j.colsurfb.2025.114688_bib37","doi-asserted-by":"crossref","first-page":"13112","DOI":"10.1039\/C5DT01467K","article-title":"BSA-directed synthesis of CuS nanoparticles as a biocompatible photothermal agent for tumor ablation in vivo","volume":"44","author":"Zhang","year":"2015","journal-title":"Dalton Trans."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092777652500195X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092777652500195X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:19:50Z","timestamp":1762330790000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092777652500195X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":37,"alternative-id":["S092777652500195X"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.114688","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PEGylated PAMAM dendrimer nanoplatform for co-delivery of chemotherapeutic agents and inorganic nanoparticles enhancing chemo-photothermal combination therapy","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.114688","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114688"}}