{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T06:02:12Z","timestamp":1793772132329,"version":"4.6.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012431","name":"Jiangsu Agricultural Science and Technology Independent Innovation Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012431","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005052","name":"Nano Mission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009604","name":"Science and Technology Bureau of Changchun","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009604","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012336","name":"Major State Basic Research Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017945","name":"Jilin Provincial Postdoctoral Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017945","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018806","name":"Department of Science and Technology of Hubei Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018806","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018541","name":"Science Fund for Distinguished Young Scholars of Jiangsu Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018541","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.colsurfb.2025.114873","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T11:52:48Z","timestamp":1749469968000},"page":"114873","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Artesunate carbon dots for attenuating periodontal inflammation and promoting bone regeneration   activation of AMPK"],"prefix":"10.1016","volume":"254","author":[{"given":"Shuo","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinzhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqing","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiling","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangheng","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanlin","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8650-9104","authenticated-orcid":false,"given":"Zhihui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2025.114873_bib1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1007\/s00018-024-05424-8","article-title":"Tropomodulin1 exacerbates inflammatory response in macrophages by negatively regulating LPS-induced TLR4 endocytosis","volume":"81","author":"Geng","year":"2024","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib2","doi-asserted-by":"crossref","DOI":"10.1080\/21505594.2024.2427234","article-title":"Insight into the role of macrophages in periodontitis restoration and development","volume":"15","author":"Mo","year":"2024","journal-title":"Virulence"},{"key":"10.1016\/j.colsurfb.2025.114873_bib3","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/JLB.1RU0818-310R","article-title":"Macrophage immunomodulation in chronic osteolytic diseases-the case of periodontitis","volume":"105","author":"Sima","year":"2019","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.colsurfb.2025.114873_bib4","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1177\/00220345221090879","article-title":"Periodontal stem cells synthesize maresin conjugate in tissue regeneration 3","volume":"101","author":"Rakian","year":"2022","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.colsurfb.2025.114873_bib5","article-title":"Photo-crosslinked bioactive BG\/BMSCs@GelMA hydrogels for bone-defect repairs","volume":"6","author":"Dai","year":"2023","journal-title":"Mater. Today Bio"},{"issue":"21-22","key":"10.1016\/j.colsurfb.2025.114873_bib6","doi-asserted-by":"crossref","DOI":"10.1089\/ten.tea.2013.0633","article-title":"Adaptive immune response inhibits ectopic mature bone formation induced by BMSCs\/BCP\/plasma composite in immune-competent mice","volume":"20","author":"Bouvet-Gerbettaz","year":"2014","journal-title":"Tissue Eng. Part A"},{"key":"10.1016\/j.colsurfb.2025.114873_bib7","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00162-21","article-title":"Dental plaque microbial resistomes of periodontal health and disease and their changes after scaling and root planing therapy","volume":"6","author":"Kang","year":"2021","journal-title":"mSphere"},{"key":"10.1016\/j.colsurfb.2025.114873_bib8","article-title":"Antibacterial efficiency of adjuvant photodynamic therapy and high-power diode laser in the treatment of young permanent teeth with chronic periapical periodontitis, A prospective clinical study","volume":"41","author":"Dragana","year":"2023","journal-title":"Photo Photo Ther."},{"key":"10.1016\/j.colsurfb.2025.114873_bib9","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s12010-022-04127-9","article-title":"Periodontitis: an oral disease with severe consequences","volume":"195","author":"Ray","year":"2023","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.colsurfb.2025.114873_bib10","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/s41368-023-00225-4","article-title":"CD301b+ macrophage: the new booster for activating bone regeneration in periodontitis treatment","volume":"15","author":"Wang","year":"2023","journal-title":"Int. J. Oral. Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib11","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1038\/nm.2471","article-title":"The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine","volume":"17","author":"Tu","year":"2011","journal-title":"Nat. Med."},{"key":"10.1016\/j.colsurfb.2025.114873_bib12","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/SLA.0000000000001664","article-title":"Artesunate protects against the organ injury and dysfunction induced by severe hemorrhage and resuscitation","volume":"265","author":"Sordi","year":"2017","journal-title":"Ann. Surg."},{"key":"10.1016\/j.colsurfb.2025.114873_bib13","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.pharmthera.2013.12.001","article-title":"Artemisinins: pharmacological actions beyond anti-malarial","volume":"142","author":"Ho","year":"2014","journal-title":"Pharm. Ther."},{"key":"10.1016\/j.colsurfb.2025.114873_bib14","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1186\/s12903-024-04127-7","article-title":"Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats","volume":"24","author":"Luo","year":"2024","journal-title":"BMC Oral. Health"},{"key":"10.1016\/j.colsurfb.2025.114873_bib15","doi-asserted-by":"crossref","first-page":"8069","DOI":"10.1021\/acsnano.1c00629","article-title":"Carbon-based nanomaterials: promising antiviral agents to combat COVID-19 in the microbial-resistant era","volume":"15","author":"Serrano-Aroca","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2025.114873_bib16","article-title":"Acoustic cavitation assisted synthesis and characterization of photoluminescent carbon quantum dots for biological applications and their future prospective","volume":"25","author":"Das","year":"2021","journal-title":"NanoStruct. NanoObjects"},{"key":"10.1016\/j.colsurfb.2025.114873_bib17","article-title":"Rational design of multi-color-emissive carbon dots in a single reaction system by hydrothermal","volume":"8","author":"Wang","year":"2020","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202100196","article-title":"Metformin carbon dots for promoting periodontal bone regeneration via activation of ERK\/AMPK Pathway","volume":"10","author":"Ren","year":"2021","journal-title":"Adv. Health Mater."},{"key":"10.1016\/j.colsurfb.2025.114873_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120110","article-title":"Renal clearable Hafnium-doped carbon dots for CT\/Fluorescence imaging of orthotopic liver cancer","volume":"255","author":"Su","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2025.114873_bib20","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s42823-022-00339-5","article-title":"Current scenario and recent advancement of doped carbon dots: a short review scientocracy update (2013\u20132022)","volume":"32","author":"Ghosh","year":"2022","journal-title":"Carbon Lett."},{"key":"10.1016\/j.colsurfb.2025.114873_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2023.113173","article-title":"Genistein carbon dots exhibit antioxidant and anti-inflammatory effects in vitro","volume":"223","author":"Jaiswal","year":"2023","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2025.114873_bib22","article-title":"Antibacterial carbon dots-based composites","volume":"19","author":"Huang","year":"2023","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2025.114873_bib23","doi-asserted-by":"crossref","first-page":"671","DOI":"10.7150\/thno.39863","article-title":"Carbon dots as potent antimicrobial agents","volume":"10","author":"Dong","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.colsurfb.2025.114873_bib24","doi-asserted-by":"crossref","first-page":"11288","DOI":"10.1021\/acsami.6b01577","article-title":"Phosphorus and nitrogen dual-doped hollow carbon dot as a nanocarrier for doxorubicin delivery and biological imaging","volume":"8","author":"Gong","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2025.114873_bib25","doi-asserted-by":"crossref","DOI":"10.1002\/advs.201901316","article-title":"Evolution and synthesis of carbon dots: from carbon dots to carbonized polymer dots","volume":"6","author":"Xia","year":"2019","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib26","doi-asserted-by":"crossref","first-page":"7135","DOI":"10.1039\/C7NR02128C","article-title":"One-step hydrothermal synthesis of photoluminescent carbon nanodots with selective antibacterial activity against Porphyromonas gingivalis","volume":"9","author":"Liu","year":"2017","journal-title":"Nanoscale"},{"key":"10.1016\/j.colsurfb.2025.114873_bib27","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jcis.2021.12.192","article-title":"Solution-processable carbon dots with efficient solid-state red\/near-infrared emission","volume":"613","author":"Qu","year":"2022","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib28","article-title":"Deep red emissive carbonized polymer dots with unprecedented narrow full width at half maximum","volume":"32","author":"Liu","year":"2020","journal-title":"Adv. Mater."},{"key":"10.1016\/j.colsurfb.2025.114873_bib29","doi-asserted-by":"crossref","first-page":"9140","DOI":"10.1021\/acsanm.2c01444","article-title":"Synthesis of carbon dots with carbogenic \u03c0-conjugated domains for full-band UV shielding","volume":"5","author":"Chen","year":"2022","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.colsurfb.2025.114873_bib30","doi-asserted-by":"crossref","first-page":"9301","DOI":"10.1021\/acssuschemeng.9b00325","article-title":"Highly emissive carbon dots in solid state and their applications in light-emitting devices and visible light communication","volume":"7","author":"Liu","year":"2019","journal-title":"ACS Sustain. Chem. Eng."},{"key":"10.1016\/j.colsurfb.2025.114873_bib31","doi-asserted-by":"crossref","first-page":"8894","DOI":"10.1021\/acs.jpcc.9b11732","article-title":"Citric acid based carbon dots with amine type stabilizers: pH-specific luminescence and quantum yield characteristics","volume":"124","author":"Meierhofer","year":"2020","journal-title":"J. Phys. Chem. C."},{"key":"10.1016\/j.colsurfb.2025.114873_bib32","article-title":"Carbonized platycladus orientalis derived carbon dots accelerate hemostasis through activation of platelets and coagulation pathways","volume":"19","author":"Liang","year":"2023","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2025.114873_bib33","doi-asserted-by":"crossref","first-page":"9301","DOI":"10.1021\/acssuschemeng.9b00325","article-title":"Highly emissive carbon dots in solid state and their applications in light-emitting devices and visible light communication","volume":"7","author":"Liu","year":"2019","journal-title":"ACS Sustain Chem. Eng."},{"key":"10.1016\/j.colsurfb.2025.114873_bib34","doi-asserted-by":"crossref","first-page":"737","DOI":"10.3390\/ijms25020737","article-title":"Mitochondria: an emerging unavoidable link in the pathogenesis of periodontitis caused by Porphyromonas gingivalis","volume":"6","author":"Luo","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib35","first-page":"1539","article-title":"Porphyromonas gingivalis in the development of periodontitis: impact on dysbiosis and inflammation","volume":"77","author":"Gasmi Benahmed","year":"2022","journal-title":"Arch. Razi Inst."},{"key":"10.1016\/j.colsurfb.2025.114873_bib36","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/omi.12305","article-title":"In vivo and ex vivo actions of a novel P. gingivalis inhibitor on multi-species biofilm, inflammatory response, and periodontal bone loss","volume":"35","author":"Ho","year":"2020","journal-title":"Mol. Oral. Microbiol."},{"key":"10.1016\/j.colsurfb.2025.114873_bib37","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1186\/s12903-021-01971-9","article-title":"Polymicrobial synergy stimulates Porphyromonas gingivalis survival and gingipain expression in a multi-species subgingival community","volume":"21","author":"Davies","year":"2021","journal-title":"BMC Oral. Health"},{"key":"10.1016\/j.colsurfb.2025.114873_bib38","doi-asserted-by":"crossref","first-page":"3345","DOI":"10.3390\/cells11213345","article-title":"Biological roles of fibroblasts in periodontal diseases","volume":"11","author":"Naruishi","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.colsurfb.2025.114873_bib39","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20194387","article-title":"Artesunate inhibits osteoclastogenesis through the miR-503\/RANK axis","volume":"40","author":"Huang","year":"2020","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.colsurfb.2025.114873_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.140434","article-title":"Gelatin methacryloyl-phenylboronic acid\/Hydroxyadamantane self-healing microgels for the periodontitis treatment by promoting alveolar bone regeneration","volume":"303","author":"Luo","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"5","key":"10.1016\/j.colsurfb.2025.114873_bib41","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00844-2023","article-title":"RUNX2 is stabilised by TAZ and drives pulmonary artery calcification and lung vascular remodelling in pulmonary hypertension due to left heart disease","volume":"64","author":"Liu","year":"2024","journal-title":"Eur. Respir. J."},{"issue":"5","key":"10.1016\/j.colsurfb.2025.114873_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24054305","article-title":"Atf7ip inhibits osteoblast differentiation via negative regulation of the Sp7 transcription factor","volume":"24","author":"Hu","year":"2023","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib43","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41421-024-00689-6","article-title":"Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis","volume":"10","author":"Zhu","year":"2024","journal-title":"Cell Discov."},{"key":"10.1016\/j.colsurfb.2025.114873_bib44","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1089\/ten.teb.2016.0454","article-title":"Osteoblast differentiation and bone matrix formation In Vivo and In Vitro,","volume":"23","author":"Blair","year":"2017","journal-title":"Tissue Eng. Part B Rev."},{"key":"10.1016\/j.colsurfb.2025.114873_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2023.113614","article-title":"AMP-activated protein kinase: an energy sensor and survival mechanism in the reinstatement of metabolic homeostasis","volume":"428","author":"Sharma","year":"2023","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.colsurfb.2025.114873_bib46","doi-asserted-by":"crossref","first-page":"13516","DOI":"10.3390\/ijms241713516","article-title":"Chlorogenic acid alleviates LPS-induced inflammation and oxidative stress by modulating CD36\/AMPK\/PGC-1\u03b1 in RAW 264.7 macrophages","volume":"24","author":"Gu","year":"2023","journal-title":"Int J. Mol. Sci."},{"key":"10.1016\/j.colsurfb.2025.114873_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.140736","article-title":"Molecular characterization of AMP-activated protein kinase (AMPK) \u03b11\/\u03b12 from Cyprinus carpio and its roles in glucolipid metabolism and immune response","volume":"303","author":"Zhi","year":"2025","journal-title":"Int J. Biol. Macromol."},{"key":"10.1016\/j.colsurfb.2025.114873_bib48","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s13075-018-1699-4","article-title":"Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling","volume":"20","author":"McWherter","year":"2018","journal-title":"Arthritis Res Ther."},{"key":"10.1016\/j.colsurfb.2025.114873_bib49","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.4049\/jimmunol.2200182","article-title":"FABP5 deficiency impaired macrophage inflammation by regulating AMPK\/NF-\u03baB signaling pathway","volume":"209","author":"Hou","year":"2022","journal-title":"J. Immunol."},{"key":"10.1016\/j.colsurfb.2025.114873_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1123700","article-title":"Anti-malarial artesunate ameliorates atherosclerosis by modulating arterial inflammatory responses via inhibiting the NF-\u03baB-NLRP3 inflammasome pathway","volume":"14","author":"Cen","year":"2023","journal-title":"Front. Pharm."},{"key":"10.1016\/j.colsurfb.2025.114873_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1476030","article-title":"NF-\u03baB signaling pathway in tumor microenvironment","volume":"15","author":"Cao","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.colsurfb.2025.114873_bib52","article-title":"Anti-osteoclast effect of exportin-1 inhibitor eltanexor on osteoporosis depends on nuclear accumulation of I\u03baB\u03b1-NF-\u03baB p65 complex","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Pharm."},{"key":"10.1016\/j.colsurfb.2025.114873_bib53","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1126\/science.aay3878","article-title":"cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation","volume":"367","author":"Muendlein","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.colsurfb.2025.114873_bib54","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.actbio.2019.06.023","article-title":"Surface treatments on titanium implants via nanostructured ceria for antibacterial and anti-inflammatory capabilities","volume":"94","author":"Li","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.colsurfb.2025.114873_bib55","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1210\/en.2017-00357","article-title":"Osteoblast AMP-activated protein kinase regulates postnatal skeletal development in male mice","volume":"159","author":"Kanazawa","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.colsurfb.2025.114873_bib56","first-page":"2535","article-title":"AMP-activated protein kinase stimulates osteoblast differentiation and mineralization through autophagy induction","volume":"41","author":"Li","year":"2018","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.colsurfb.2025.114873_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/03008207.2025.2540041","article-title":"Creatine promotes osteogenic differentiation of dental pulp stem cells via the AMPK-ULK1-autophagy axis","volume":"11","author":"Liu","year":"2025","journal-title":"Connect Tissue Res."},{"key":"10.1016\/j.colsurfb.2025.114873_bib58","doi-asserted-by":"crossref","first-page":"3561","DOI":"10.1021\/acsbiomaterials.9b00607","article-title":"Exosomes secreted by stem cells from human exfoliated deciduous teeth promote alveolar bone defect repair through the regulation of angiogenesis and osteogenesis","volume":"5","author":"Wu","year":"2019","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.colsurfb.2025.114873_bib59","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.actbio.2019.01.001","article-title":"An injectable and thermosensitive hydrogel: promoting periodontal regeneration by controlled-release of aspirin and erythropoietin","volume":"86","author":"Xu","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.colsurfb.2025.114873_bib60","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1600-051X.1991.tb01116.x","article-title":"Applicability of an image analysis system in alveolar bone loss measurement","volume":"18","author":"Verdonschot","year":"1991","journal-title":"J. Clin. Periodo"},{"key":"10.1016\/j.colsurfb.2025.114873_bib61","article-title":"Development of an injectable salicylic acid-choline eutectic hydrogel for enhanced treatment of periodontitis","author":"Zhang","year":"2025","journal-title":"Mater. Horiz."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776525003807?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776525003807?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,9]],"date-time":"2025-08-09T18:41:27Z","timestamp":1754764887000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776525003807"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":61,"alternative-id":["S0927776525003807"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.114873","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Artesunate carbon dots for attenuating periodontal inflammation and promoting bone regeneration via activation of AMPK","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.114873","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114873"}}