{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:56:03Z","timestamp":1793134563281,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62375146"],"award-info":[{"award-number":["62375146"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62374097"],"award-info":[{"award-number":["62374097"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004387","name":"Ningbo University","doi-asserted-by":"publisher","award":["HY202405"],"award-info":[{"award-number":["HY202405"]}],"id":[{"id":"10.13039\/501100004387","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.colsurfb.2025.114999","type":"journal-article","created":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T04:04:11Z","timestamp":1754366651000},"page":"114999","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"P1","title":["PCA-assisted label-free surface-enhanced Raman scattering detection of exosomes in prostate cancer at different stages based on dual-layer membrane g-C3N4@MXene SERS platform prepared by electrodeposition"],"prefix":"10.1016","volume":"256","author":[{"given":"Jialong","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasheng","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenjie","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"13","key":"10.1016\/j.colsurfb.2025.114999_bib1","doi-asserted-by":"crossref","first-page":"4889","DOI":"10.7498\/aps.70.20201447","article-title":"Single-molecule surface-enhanced Raman spectroscopy (SM-SERS): characteristics and analysis","volume":"70","author":"Zhao","year":"2021","journal-title":"Acta Phys. Sin."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib2","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1038\/s41467-021-21431-w","article-title":"A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy","volume":"12","author":"Li","year":"2021","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib3","article-title":"Enhanced SERS detection of the colorectal cancer biomarker utilizing a two-dimensional silver substrate","volume":"245","author":"Nie","year":"2025","journal-title":"Colloids Surf. B."},{"issue":"6","key":"10.1016\/j.colsurfb.2025.114999_bib4","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/s41551-019-0356-9","article-title":"Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip","volume":"3","author":"Zhang","year":"2019","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.colsurfb.2025.114999_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.148120","article-title":"Biorthogonal chemistry mediated cell engineering for advanced cell and cell-derived vesicle therapies: principles, progresses, and remaining challenges","volume":"480","author":"Pan","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"6586","key":"10.1016\/j.colsurfb.2025.114999_bib6","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1126\/science.aay9040","article-title":"Early detection of cancer","volume":"375","author":"Crosby","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.colsurfb.2025.114999_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111599","article-title":"Interference-free and high precision biosensor based on surface enhanced Raman spectroscopy integrated with surface molecularly imprinted polymer technology for tumor biomarker detection in human blood","volume":"143","author":"Lin","year":"2019","journal-title":"Biosens. Bioelectron."},{"issue":"18","key":"10.1016\/j.colsurfb.2025.114999_bib8","doi-asserted-by":"crossref","first-page":"8957","DOI":"10.1039\/D4CS00090K","article-title":"Biomedical SERS the current state and future trends","volume":"53","author":"May","year":"2024","journal-title":"Chem. Soc. Rev."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib9","article-title":"An electrochemical\/SERS dual-mode immunosensor using TMB\/Au nanotag and Au@2D-MoS2 modified screen-printed electrode for sensitive detection of prostate cancer biomarker","volume":"243","author":"Yaiwong","year":"2024","journal-title":"Colloids Surf. B."},{"issue":"6","key":"10.1016\/j.colsurfb.2025.114999_bib10","article-title":"Sesames for metabolic phenotyping and prostate cancer diagnosis","volume":"5","author":"Bi","year":"2024","journal-title":"Cell Rep. Med."},{"issue":"5","key":"10.1016\/j.colsurfb.2025.114999_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202411747","article-title":"Dual-enhanced SERS satellite immunol nanocomplex for multiple PSA-mediated PHI assay toward clinical prostate cancer screening","volume":"12","author":"Chen","year":"2024","journal-title":"Adv. Sci."},{"issue":"6","key":"10.1016\/j.colsurfb.2025.114999_bib12","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1464-410X.2012.11329.x","article-title":"From prostate-specific antigen (PSA) to precursor PSA (proPSA) isoforms: a review of the emerging role of proPSAs in the detection and management of early prostate cancer","volume":"112","author":"Hori","year":"2012","journal-title":"BJU Int."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib13","article-title":"Machine learning-based exosome profiling of multi-receptor SERS sensors for differentiating adenocarcinoma in situ from early-stage invasive adenocarcinoma","volume":"236","year":"2024","journal-title":"Colloids Surf. B."},{"issue":"6478","key":"10.1016\/j.colsurfb.2025.114999_bib14","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1126\/science.aau6977","article-title":"The biology, function, and biomedical applications of exosomes","volume":"367","author":"Kalluri","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.colsurfb.2025.114999_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.149012","article-title":"A microdroplet SERS-RCA biosensor with enhanced specificity and reproducibility for profiling dual miRNAs in idiopathic pulmonary fibrosis diagnosis and monitoring","volume":"482","author":"Qian","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"7","key":"10.1016\/j.colsurfb.2025.114999_bib16","doi-asserted-by":"crossref","first-page":"7897","DOI":"10.1021\/acsami.9b19421","article-title":"Label-free surface-enhanced Raman spectroscopy biosensor for on-site breast cancer detection using human tears","volume":"12","author":"Kim","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2025.114999_bib17","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.jconrel.2022.12.027","article-title":"Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications","volume":"353","author":"Mondal","year":"2023","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2025.114999_bib18","first-page":"23","article-title":"Cancer-derived exosomes as novel biomarkers in metastatic gastrointestinal cancer","volume":"67","author":"Zhong","year":"2024","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib19","article-title":"Highly sensitive SERS substrates based on MoS2-Au nanocomposites for detection of hazardous dyes and infectious bacteria","volume":"252","author":"Kaushik","year":"2025","journal-title":"Colloids Surf. B."},{"key":"10.1016\/j.colsurfb.2025.114999_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsusc.2019.143825","article-title":"Black phosphorus-Au filter paper-based three-dimensional SERS substrate for rapid detection of foodborne bacteria","volume":"497","author":"Huang","year":"2019","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.colsurfb.2025.114999_bib21","first-page":"52","article-title":"Charge-transfer resonance and electromagnetic enhancement synergistically enabling MXenes with excellent SERS sensitivity for SARS-CoV-2S protein detection","volume":"13","author":"Peng","year":"2021","journal-title":"NanoMicro Lett."},{"key":"10.1016\/j.colsurfb.2025.114999_bib22","first-page":"2998","article-title":"Bifunctional Mo2N nanoparticles with nanozyme and SERS activity: a versatile platform for sensitive detection of biomarkers in serum samples","volume":"96","author":"Chen","year":"2024","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib23","article-title":"Nanoengineered phosphorus doped graphitic carbon nitride based ultrasensitive biosensing platform for swine flu detection","volume":"230","author":"Nirbhaya","year":"2023","journal-title":"Colloids Surf. B."},{"issue":"12","key":"10.1016\/j.colsurfb.2025.114999_bib24","doi-asserted-by":"crossref","first-page":"7159","DOI":"10.1021\/acs.chemrev.6b00075","article-title":"Graphitic carbon nitride (g-C3N4)-based photocatalysts for artificial photosynthesis and environmental remediation: are we a step closer to achieving sustainability","volume":"116","author":"Ong","year":"2016","journal-title":"Chem. Rev."},{"issue":"4","key":"10.1016\/j.colsurfb.2025.114999_bib25","first-page":"47","article-title":"Recent advances of graphitic carbon nitride-based structures and applications in catalyst, sensing, imaging, and LEDs","volume":"9","author":"Wang","year":"2017","journal-title":"NanoMicro Lett."},{"key":"10.1016\/j.colsurfb.2025.114999_bib26","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.snb.2013.04.099","article-title":"Improved speed of hydrogen detection by schottky diodes on InP with electrophoretically deposited pt nanoparticles and graphite contacts","volume":"184","author":"Zdansky","year":"2013","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.colsurfb.2025.114999_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.151638","article-title":"Electrochemically assisted preparation of graphitic carbon nitride nanosheet membranes for efficient water purification","volume":"490","author":"Zhou","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2025.114999_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.126223","article-title":"Multifunctional g-C3N4\/Ag NPs intercalated GO composite membrane for SERS detection and photocatalytic degradation of paraoxon-ethyl","volume":"402","author":"Zhao","year":"2020","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2025.114999_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsusc.2023.158010","article-title":"Facile synthesis of ZnO\/Ag\/g-C3N4 nanocomposites for multiple applications in photocatalytic degradation and photoactivated NO2 sensing","volume":"638","author":"Li","year":"2023","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.colsurfb.2025.114999_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2021.214338","article-title":"A critical review on graphitic carbon nitride (g-C3N4)-based materials: preparation, modification and environmental application","volume":"453","author":"Wang","year":"2022","journal-title":"Coord. Chem. Rev."},{"issue":"2","key":"10.1016\/j.colsurfb.2025.114999_bib31","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1039\/D3SU00382E","article-title":"Graphitic carbon nitride (g-C3N4) as an emerging photocatalyst for sustainable environmental applications: a comprehensive review","volume":"2","author":"Bhanderi","year":"2024","journal-title":"RSC Sustain"},{"key":"10.1016\/j.colsurfb.2025.114999_bib32","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jmst.2022.02.035","article-title":"Review on g-C3N4-based S-scheme heterojunction photocatalysts","volume":"125","author":"Li","year":"2022","journal-title":"J. Mater. Sci. Technol."},{"key":"10.1016\/j.colsurfb.2025.114999_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.jallcom.2022.167928","article-title":"Enhancing visible-light degradation performance of g-C3N4 on organic pollutants by constructing heterojunctions via combining tubular g-C3N4 with Bi2O3 nanosheets","volume":"934","author":"Pei","year":"2023","journal-title":"J. Alloy. Compd."},{"key":"10.1016\/j.colsurfb.2025.114999_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.130290","article-title":"Recyclable and Green AuBPs@MoS2@tinfoil box for high throughput SERS tracking of diquat in complex compounds","volume":"344","author":"Jiang","year":"2021","journal-title":"Sens. Actuators B"},{"issue":"10","key":"10.1016\/j.colsurfb.2025.114999_bib35","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202004129","article-title":"Hetero-MXenes: theory, synthesis, and emerging applications","volume":"33","author":"Gao","year":"2021","journal-title":"Adv. Mater."},{"key":"10.1016\/j.colsurfb.2025.114999_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.seppur.2022.121037","article-title":"A self-cleaning photocatalytic composite membrane based on g-C3N4@MXene nanosheets for the removal of dyes and antibiotics from wastewater","volume":"292","author":"Zeng","year":"2022","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.colsurfb.2025.114999_bib37","article-title":"3D hollow spheres comprising MXene\/g-C3N4 heterostructre for efficient polysulfide adsorption and conversion in high-performance Li-S batteries","volume":"945","author":"Alkuder Salman","year":"2023","journal-title":"J. Electroanal. Chem."},{"issue":"6","key":"10.1016\/j.colsurfb.2025.114999_bib38","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1364\/PRJ.421415","article-title":"Lamellar hafnium ditelluride as an ultrasensitive surface-enhanced Raman scattering platform for label-free detection of uric acid","volume":"9","author":"Li","year":"2021","journal-title":"Photonics Res"},{"key":"10.1016\/j.colsurfb.2025.114999_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.155526","article-title":"Artificial intelligence assisted label-free surface-enhanced Raman scattering detection of early-stage cancer-derived exosomes based on g-C3N4\/Ag hybrid substrate prepared by electro-synthesis","volume":"498","author":"Zhao","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"17","key":"10.1016\/j.colsurfb.2025.114999_bib40","article-title":"Quantitative and specific detection of exosome miRNAs for accurate diagnosis of breast cancer using a surface-enhanced Raman scattering sensor based on plasmonic head-flocked gold nanopillars","volume":"15","author":"Lee","year":"2019","journal-title":"Small"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib41","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1038\/s41467-023-37403-1","article-title":"Single test-based diagnosis of multiple cancer types using Exosome-SERS-AI for early-stage cancers","volume":"14","author":"Shin","year":"2023","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.colsurfb.2025.114999_bib42","doi-asserted-by":"crossref","first-page":"6695","DOI":"10.1021\/acs.analchem.7b00911","article-title":"Exosome classification by pattern analysis of surface-enhanced Raman spectroscopy data for lung cancer diagnosis","volume":"89","author":"Park","year":"2017","journal-title":"Anal. Chem."},{"issue":"12","key":"10.1016\/j.colsurfb.2025.114999_bib43","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1021\/acssensors.8b01047","article-title":"Correlation between cancerous exosomes and protein markers based on surface-enhanced Raman spectroscopy (SERS) and principal component analysis (PCA)","volume":"3","author":"Shin","year":"2018","journal-title":"ACS Sens"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib44","article-title":"Surface-enhanced infrared spectroscopic study of extracellular vesicles using plasmonic gold nanoparticles","volume":"246","author":"Bebesi","year":"2025","journal-title":"Colloids Surf. B."},{"issue":"2","key":"10.1016\/j.colsurfb.2025.114999_bib45","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1021\/acssensors.8b01564","article-title":"A Label-free platform for identification of exosomes from different sources","volume":"4","author":"Yan","year":"2019","journal-title":"ACS Sens"},{"issue":"2","key":"10.1016\/j.colsurfb.2025.114999_bib46","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/jcb.29857","article-title":"Rapid and label-free identification of different cancer types based on surface-enhanced Raman scattering profiles and multivariate statistical analysis","volume":"122","author":"Fang","year":"2020","journal-title":"J. Cell. Biochem."},{"issue":"38","key":"10.1016\/j.colsurfb.2025.114999_bib47","doi-asserted-by":"crossref","first-page":"8864","DOI":"10.1021\/acs.jpclett.2c02392","article-title":"The origin of Mo2C films for surface-enhanced Raman scattering analysis: electromagnetic or chemical enhancement","volume":"13","author":"Ji","year":"2022","journal-title":"J. Phys. Chem. Lett."},{"key":"10.1016\/j.colsurfb.2025.114999_bib48","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1016\/j.jcis.2021.10.118","article-title":"Graphitic carbon nitride nanosheets via acid pretreatments for promoted photocatalysis toward degradation of organic pollutants","volume":"608","author":"Meng","year":"2022","journal-title":"J. Colloid Interface Sci."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib49","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1038\/s41467-020-15484-6","article-title":"Irreversible accumulated SERS behavior of the molecule-linked silver and silver-doped titanium dioxide hybrid system","volume":"11","author":"Zhou","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.colsurfb.2025.114999_bib50","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.snb.2017.11.080","article-title":"SERS activated platform with three-dimensional hot spots and tunable nanometer gap","volume":"258","author":"Zhang","year":"2018","journal-title":"Sens. Actuators B."},{"key":"10.1016\/j.colsurfb.2025.114999_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.127806","article-title":"Fast electrophoretic preparation of large-area two-dimensional titanium carbide membranes for ion sieving","volume":"408","author":"Deng","year":"2021","journal-title":"Chem. Eng. J."},{"issue":"11","key":"10.1016\/j.colsurfb.2025.114999_bib52","doi-asserted-by":"crossref","first-page":"16282","DOI":"10.1002\/anie.202116282","article-title":"In situ growth of three-dimensional MXene\/metal-organic framework composites for high-performance supercapacitors","volume":"61","author":"Liu","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"issue":"9","key":"10.1016\/j.colsurfb.2025.114999_bib53","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1038\/s41565-024-01691-5","article-title":"Electricity generated by upstream proton diffusion in two-dimensional nanochannels","volume":"19","author":"Xia","year":"2024","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.colsurfb.2025.114999_bib54","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.apsusc.2014.05.036","article-title":"Enhanced visible light photocatalytic performance of g-C3N4 photocatalysts co-doped with iron and phosphorus","volume":"311","author":"Hu","year":"2014","journal-title":"Appl. Surf. Sci."},{"issue":"14","key":"10.1016\/j.colsurfb.2025.114999_bib55","doi-asserted-by":"crossref","first-page":"19655","DOI":"10.1007\/s10854-021-06488-z","article-title":"Porous g-C3N4 nanosheets through facile thermal polymerization of melamine in the air for photocatalyst application","volume":"32","author":"Molaei","year":"2021","journal-title":"J. Mater. Scie. Mater. Electron."},{"key":"10.1016\/j.colsurfb.2025.114999_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsusc.2022.155351","article-title":"Aging of 2D MXene nanoparticles in air: an XPS and TEM study","volume":"610","author":"Mi\u010du\u0161\u00edk","year":"2023","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.colsurfb.2025.114999_bib57","doi-asserted-by":"crossref","first-page":"582","DOI":"10.3389\/fchem.2019.00582","article-title":"Study of chemical enhancement mechanism in non-plasmonic surface enhanced Raman spectroscopy (SERS)","volume":"7","author":"Kim","year":"2019","journal-title":"Front. Chem."},{"key":"10.1016\/j.colsurfb.2025.114999_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actbio.2022.03.036","article-title":"Exosome detection via surface-enhanced Raman spectroscopy for cancer diagnosis","volume":"144","author":"Li","year":"2022","journal-title":"Acta Biomater."},{"issue":"19","key":"10.1016\/j.colsurfb.2025.114999_bib59","doi-asserted-by":"crossref","first-page":"7910","DOI":"10.1021\/acs.nanolett.2c02928","article-title":"Artificial intelligent label-free SERS profiling of serum exosomes for breast cancer diagnosis and postoperative assessment","volume":"22","author":"Xie","year":"2022","journal-title":"Nano Lett."},{"issue":"2","key":"10.1016\/j.colsurfb.2025.114999_bib60","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/jcb.29857","article-title":"Rapid and label-free identification of different cancer types based on surface-enhanced Raman scattering profiles and multivariate statistical analysis","volume":"122","author":"Fang","year":"2020","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.colsurfb.2025.114999_bib61","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.bios.2018.07.038","article-title":"Label-free distinction between p53+\/+ and p53 -\/- colon cancer cells using a graphene-based SERS platform","volume":"118","author":"Liang","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.colsurfb.2025.114999_bib62","first-page":"1390","article-title":"The updated role of exosomes proteins in the diagnosis, prognosis, and treatment of cancer","author":"Wang","year":"2022","journal-title":"Exp. Mol. Med."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.114999_bib63","first-page":"16287","article-title":"Surface-enhanced Raman spectroscopy for biomedical applications: recent advanced and future challenges","volume":"17","author":"Linley","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776525005065?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776525005065?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T04:57:18Z","timestamp":1762577838000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776525005065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":63,"alternative-id":["S0927776525005065"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.114999","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PCA-assisted label-free surface-enhanced Raman scattering detection of exosomes in prostate cancer at different stages based on dual-layer membrane g-C3N4@MXene SERS platform prepared by electrodeposition","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.114999","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114999"}}