{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:30:03Z","timestamp":1792031403927,"version":"4.4.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Health Research Project of Hunan Provincial Health Commission"],"award-info":[{"award-number":["Health Research Project of Hunan Provincial Health Commission"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["W20243065"],"award-info":[{"award-number":["W20243065"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81673614"],"award-info":[{"award-number":["81673614"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2024JJ8126"],"award-info":[{"award-number":["2024JJ8126"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.colsurfb.2025.115297","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T22:56:18Z","timestamp":1763765778000},"page":"115297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Platelet membrane-fused and cardiac homing peptide-modified liposomes deliver puerarin to attenuate myocardial ischemia\/reperfusion injury by inhibiting pyroptosis"],"prefix":"10.1016","volume":"259","author":[{"given":"Shengnan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiyong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junyong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongbiao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongbin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiantian","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"21","key":"10.1016\/j.colsurfb.2025.115297_bib1","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1016\/j.jacc.2022.03.370","article-title":"Disruption of circadian rhythms by shift work exacerbates reperfusion injury in myocardial infarction","volume":"79","author":"Zhao","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"issue":"11","key":"10.1016\/j.colsurfb.2025.115297_bib2","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/nrcardio.2017.102","article-title":"New and revisited approaches to preserving the reperfused myocardium","volume":"14","author":"Kloner","year":"2017","journal-title":"Nat. Rev. Cardiol."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.115297_bib3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.apsb.2022.08.007","article-title":"Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury: cumulative evidence for future cardioprotective strategies","volume":"13","author":"Yanpiset","year":"2023","journal-title":"Acta Pharm. Sin. B"},{"issue":"6","key":"10.1016\/j.colsurfb.2025.115297_bib4","doi-asserted-by":"crossref","first-page":"H1553","DOI":"10.1152\/ajpheart.00158.2018","article-title":"Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury","volume":"315","author":"Toldo","year":"2018","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"9","key":"10.1016\/j.colsurfb.2025.115297_bib5","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1038\/s41401-021-00845-8","article-title":"The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1beta\/p38 MAPK pathway","volume":"43","author":"Su","year":"2022","journal-title":"Acta Pharm. Sin."},{"issue":"17","key":"10.1016\/j.colsurfb.2025.115297_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241713169","article-title":"Puerarin inhibits NLRP3-Caspase-1-GSDMD-mediated pyroptosis via P2X7 receptor in cardiomyocytes and macrophages","volume":"24","author":"Sun","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.colsurfb.2025.115297_bib7","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1248\/bpb.b22-00174","article-title":"Puerarin protects against myocardial ischemia\/reperfusion injury by inhibiting ferroptosis","volume":"46","author":"Ding","year":"2023","journal-title":"Biol. Pharm. Bull."},{"issue":"2","key":"10.1016\/j.colsurfb.2025.115297_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22020928","article-title":"Enhancing the physiochemical properties of puerarin via L-proline co-crystallization: synthesis, characterization, and dissolution studies of two phases of pharmaceutical co-crystals","volume":"22","author":"Inam","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.colsurfb.2025.115297_bib9","doi-asserted-by":"crossref","first-page":"7997","DOI":"10.2147\/IJN.S468394","article-title":"Puerarin-loaded liposomes co-modified by ischemic myocardium-targeting peptide and triphenylphosphonium cations ameliorate myocardial ischemia-reperfusion injury","volume":"19","author":"Wang","year":"2024","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2025.115297_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2023.113680","article-title":"Platelet membrane-derived biomimetic microbubbles with enhanced targeting ability for the early detection of myocardial ischemia-reperfusion injury","volume":"234","author":"Bai","year":"2024","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2025.115297_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2024.114460","article-title":"Platelet-mimicking nanoparticles loaded with diallyl trisulfide for mitigating myocardial ischemia-reperfusion injury in rats","volume":"248","author":"Chen","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2025.115297_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.124093","article-title":"Cisplatin-loaded mesoporous polydopamine nanoparticles capped with MnO(2) and coated with platelet membrane provide synergistic anti-tumor therapy","volume":"656","author":"Zhang","year":"2024","journal-title":"Int. J. Pharm."},{"issue":"5","key":"10.1016\/j.colsurfb.2025.115297_bib13","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.yjmcc.2011.02.003","article-title":"Identification of targeting peptides for ischemic myocardium by in vivo phage display","volume":"50","author":"Kanki","year":"2011","journal-title":"J. Mol. Cell Cardiol."},{"issue":"28","key":"10.1016\/j.colsurfb.2025.115297_bib14","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1080\/17435889.2024.2402678","article-title":"Cardiac-targeted and ROS-responsive liposomes containing puerarin for attenuating myocardial ischemia-reperfusion injury","volume":"19","author":"Wang","year":"2024","journal-title":"Nanomedicine (Lond)"},{"issue":"7","key":"10.1016\/j.colsurfb.2025.115297_bib15","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1016\/j.xphs.2024.04.005","article-title":"Preparation of puerarin long circulating liposomes and its effect on osteoporosis in castrated rats","volume":"113","author":"Wang","year":"2024","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2025.115297_bib16","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.biomaterials.2018.01.018","article-title":"Natural killer cell membrane infused biomimetic liposomes for targeted tumor therapy","volume":"160","author":"Pitchaimani","year":"2018","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.115297_bib17","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1080\/21691401.2019.1577887","article-title":"Nano-erythrocyte membrane-chaperoned 5-fluorouracil liposomes as biomimetic delivery platforms to target hepatocellular carcinoma cell lines","volume":"47","author":"AlQahtani","year":"2019","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"45","key":"10.1016\/j.colsurfb.2025.115297_bib18","doi-asserted-by":"crossref","first-page":"53671","DOI":"10.1021\/acsami.1c18061","article-title":"Targeting ferroptosis by polydopamine nanoparticles protects heart against ischemia\/reperfusion injury","volume":"13","author":"Zhang","year":"2021","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"6","key":"10.1016\/j.colsurfb.2025.115297_bib19","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1097\/ALN.0b013e3181bdf9f4","article-title":"Differential role of Pim-1 kinase in anesthetic-induced and ischemic preconditioning against myocardial infarction","volume":"111","author":"Stumpner","year":"2009","journal-title":"Anesthesiology"},{"key":"10.1016\/j.colsurfb.2025.115297_bib20","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jconrel.2023.10.023","article-title":"Ginsenoside Rg3 endows liposomes with prolonged blood circulation and reduced accelerated blood clearance","volume":"364","author":"Xia","year":"2023","journal-title":"J. Control Release"},{"issue":"2","key":"10.1016\/j.colsurfb.2025.115297_bib21","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1161\/CIRCULATIONAHA.116.024590","article-title":"Exosomal MicroRNA transfer into macrophages mediates cellular postconditioning","volume":"136","author":"de Couto","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.colsurfb.2025.115297_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.127296","article-title":"Biomimetic liposomes hybrid with platelet membranes for targeted therapy of atherosclerosis","volume":"408","author":"Song","year":"2021","journal-title":"Chem. Eng. J."},{"issue":"27","key":"10.1016\/j.colsurfb.2025.115297_bib23","doi-asserted-by":"crossref","first-page":"7593","DOI":"10.1021\/acs.jafc.1c01498","article-title":"New nanocarrier system for liposomes coated with lactobacillus acidophilus S-layer protein to improve Leu-Gln-Pro-Glu absorption through the intestinal epithelium","volume":"69","author":"Jiang","year":"2021","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.colsurfb.2025.115297_bib24","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.actbio.2019.05.054","article-title":"Macrophage-derived exosome-mimetic hybrid vesicles for tumor targeted drug delivery","volume":"94","author":"Rayamajhi","year":"2019","journal-title":"Acta Biomater."},{"issue":"9","key":"10.1016\/j.colsurfb.2025.115297_bib25","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1038\/nmat4644","article-title":"Biomimetic proteolipid vesicles for targeting inflamed tissues","volume":"15","author":"Molinaro","year":"2016","journal-title":"Nat. Mater."},{"issue":"6122","key":"10.1016\/j.colsurfb.2025.115297_bib26","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1126\/science.1229568","article-title":"Minimal \"Self\" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles","volume":"339","author":"Rodriguez","year":"2013","journal-title":"Science"},{"issue":"7571","key":"10.1016\/j.colsurfb.2025.115297_bib27","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/nature15373","article-title":"Nanoparticle biointerfacing by platelet membrane cloaking","volume":"526","author":"Hu","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.colsurfb.2025.115297_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2025.114542","article-title":"Platelet membrane-cloaked biomimetic nanoparticles for targeted acute lung injury therapy","volume":"250","author":"Lin","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.115297_bib29","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-022-01445-2","article-title":"Tregs biomimetic nanoparticle to reprogram inflammatory and redox microenvironment in infarct tissue to treat myocardial ischemia reperfusion injury in mice","volume":"20","author":"Li","year":"2022","journal-title":"J. Nanobiotechnology"},{"issue":"22","key":"10.1016\/j.colsurfb.2025.115297_bib30","doi-asserted-by":"crossref","first-page":"6850","DOI":"10.1021\/ja0486059","article-title":"Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells","volume":"126","author":"Shi Kam","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.colsurfb.2025.115297_bib31","first-page":"51","article-title":"Microenvironment-responsive metal-phenolic network release platform with ROS scavenging, anti-pyroptosis, and ECM regeneration for intervertebral disc degeneration","volume":"37","author":"Zhou","year":"2024","journal-title":"Bioact. Mater."},{"issue":"2","key":"10.1016\/j.colsurfb.2025.115297_bib32","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s00011-021-01530-6","article-title":"Trimetazidine affects pyroptosis by targeting GSDMD in myocardial ischemia\/reperfusion injury","volume":"71","author":"Chen","year":"2022","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.colsurfb.2025.115297_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110990","article-title":"Uric acid aggravates myocardial ischemia\u2013reperfusion injury via ROS\/NLRP3 pyroptosis pathway","volume":"133","author":"Shen","year":"2021","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.colsurfb.2025.115297_bib34","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1021\/acsami.4c15471","article-title":"Biomimetic anisotropic-functionalized platelet-membrane-coated polymeric particles for targeted drug delivery to human breast cancer cells","volume":"17","author":"Yu","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"16","key":"10.1016\/j.colsurfb.2025.115297_bib35","article-title":"Platelet membrane nanocarriers cascade targeting delivery system to improve myocardial remodeling post myocardial ischemia-reperfusion injury","volume":"11","author":"Xu","year":"2024","journal-title":"Adv. Sci. (Weinh)"},{"issue":"5","key":"10.1016\/j.colsurfb.2025.115297_bib36","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00395-018-0696-8","article-title":"Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection","volume":"113","author":"Botker","year":"2018","journal-title":"Basic Res. Cardiol."},{"issue":"21","key":"10.1016\/j.colsurfb.2025.115297_bib37","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1080\/15384101.2022.2093598","article-title":"Astragaloside IV attenuate MI-induced myocardial fibrosis and cardiac remodeling by inhibiting ROS\/caspase-1\/GSDMD signaling pathway","volume":"21","author":"Zhang","year":"2022","journal-title":"Cell Cycle"},{"key":"10.1016\/j.colsurfb.2025.115297_bib38","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.biomaterials.2017.01.012","article-title":"A \u03c0-\u03c0 conjugation-containing soft and conductive injectable polymer hydrogel highly efficiently rebuilds cardiac function after myocardial infarction","volume":"122","author":"Bao","year":"2017","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.colsurfb.2025.115297_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/biom14010061","article-title":"Casein kinase 1 phosphomimetic mutations negatively impact connexin-43 gap junctions in human pluripotent stem cell-derived cardiomyocytes","volume":"14","author":"Al-Attar","year":"2024","journal-title":"Biomolecules"},{"key":"10.1016\/j.colsurfb.2025.115297_bib40","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.actbio.2025.05.014","article-title":"Electrohydrodynamically-printed serpentine fiber scaffolds with enhanced conductivity and elasticity for post-myocardial infarction repair","volume":"200","author":"Fu","year":"2025","journal-title":"Acta Biomater."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776525008045?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776525008045?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T11:58:50Z","timestamp":1779105530000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776525008045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":40,"alternative-id":["S0927776525008045"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.115297","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Platelet membrane-fused and cardiac homing peptide-modified liposomes deliver puerarin to attenuate myocardial ischemia\/reperfusion injury by inhibiting pyroptosis","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2025.115297","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115297"}}