{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:23:18Z","timestamp":1789669398027,"version":"4.0.1"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["2024-MS-052"],"award-info":[{"award-number":["2024-MS-052"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.colsurfb.2026.115826","type":"journal-article","created":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:02:21Z","timestamp":1778889741000},"page":"115826","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["A copper-engineered MnO\u2082 nanoplatform for potentiating STING activation and antitumor immunity in colorectal cancer"],"prefix":"10.1016","volume":"266","author":[{"given":"Jing","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenxiong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunze","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/med4.70020","article-title":"Psychosocial Challenges After Treatment for Colorectal and Anal Cancer: A Descriptive Study","volume":"3","author":"Thing Oggesen","year":"2025","journal-title":"Med. Adv."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib2","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/med4.32","article-title":"Practical management algorithms for late complications after colorectal and anal cancer\u2014Basic treatment of late complications","volume":"1","author":"Oggesen","year":"2023","journal-title":"Med. Adv."},{"issue":"7782","key":"10.1016\/j.colsurfb.2026.115826_bib3","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s41586-019-1730-1","article-title":"A view on drug resistance in cancer","volume":"575","author":"Vasan","year":"2019","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib4","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA a cancer journal clinicians"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa2407417","article-title":"Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma","volume":"392","author":"Wolchok","year":"2025","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.115826_bib6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/intimm\/dxaf002","article-title":"Cancer immunotherapy in progress-an overview of the past 130 years","volume":"37","author":"Ikeda","year":"2025","journal-title":"Int. Immunol."},{"key":"10.1016\/j.colsurfb.2026.115826_bib7","doi-asserted-by":"crossref","first-page":"103878","DOI":"10.1016\/j.redox.2025.103878","article-title":"NFS1, together with FXN, protects cells from ferroptosis and DNA damage in diffuse large B-cell lymphoma","author":"Shi","year":"2025","journal-title":"Redox Biol."},{"issue":"9","key":"10.1016\/j.colsurfb.2026.115826_bib8","doi-asserted-by":"crossref","first-page":"3335","DOI":"10.1172\/JCI83871","article-title":"Cancer immunotherapy: harnessing the immune system to battle cancer","volume":"125","author":"Yang","year":"2015","journal-title":"J. Clin. Investig."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib9","doi-asserted-by":"crossref","DOI":"10.1186\/s12943-025-02305-x","article-title":"Advances in cancer immunotherapy: historical perspectives, current developments, and future directions","volume":"24","author":"Zhang","year":"2025","journal-title":"Mol. Cancer"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115826_bib10","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.cell.2017.01.017","article-title":"Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy","volume":"168","author":"Sharma","year":"2017","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.colsurfb.2026.115826_bib11","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/s41591-018-0014-x","article-title":"Understanding the tumor immune microenvironment (TIME) for effective therapy","volume":"24","author":"Binnewies","year":"2018","journal-title":"Nat. Med."},{"key":"10.1016\/j.colsurfb.2026.115826_bib12","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.55185","article-title":"The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy","volume":"9","author":"Lim","year":"2020","journal-title":"eLife"},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib13","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/s41573-018-0007-y","article-title":"Approaches to treat immune hot, altered and cold tumours with combination immunotherapies","volume":"18","author":"Galon","year":"2019","journal-title":"Nat. Rev. Drug Discov."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib14","doi-asserted-by":"crossref","DOI":"10.1186\/s12943-024-02186-6","article-title":"Nanomedicines harnessing cGAS-STING pathway: sparking immune revitalization to transform 'cold' tumors into 'hot' tumors","volume":"23","author":"Ying","year":"2024","journal-title":"Mol. Cancer"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115826_bib15","doi-asserted-by":"crossref","first-page":"4346","DOI":"10.1021\/acsnano.4c12237","article-title":"Activating the cGAS-STING Pathway by Manganese-Based Nanoparticles Combined with Platinum-Based Nanoparticles for Enhanced Ovarian Cancer Immunotherapy","volume":"19","author":"Zhang","year":"2025","journal-title":"ACS nano"},{"issue":"6","key":"10.1016\/j.colsurfb.2026.115826_bib16","first-page":"423","article-title":"[The G and C banding chromosome patterns of the transplantable mammary adenocarcinoma in mice]","volume":"7","author":"Ling","year":"1985","journal-title":"Zhonghua Zhong Liu Za Zhi"},{"issue":"13","key":"10.1016\/j.colsurfb.2026.115826_bib17","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202400068","article-title":"Genetically Engineered Cytomembrane Nanovaccines for Cancer Immunotherapy","volume":"13","author":"Pan","year":"2024","journal-title":"Adv. Health Mater."},{"issue":"7","key":"10.1016\/j.colsurfb.2026.115826_bib18","first-page":"5510","article-title":"Bioactive ceria nanoenzymes target mitochondria in reperfusion injury to treat ischemic stroke","volume":"18","author":"Liao","year":"2024","journal-title":"ACS nano"},{"issue":"24","key":"10.1016\/j.colsurfb.2026.115826_bib19","doi-asserted-by":"crossref","first-page":"2423291","DOI":"10.1002\/adfm.202423291","article-title":"Magnetic field driven ceria nanosystems for mitochondria targeted therapy of ischemic stroke","volume":"35","author":"Liao","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"19","key":"10.1016\/j.colsurfb.2026.115826_bib20","doi-asserted-by":"crossref","first-page":"12295","DOI":"10.1021\/acsnano.4c01229","article-title":"Genetically Edited Cascade Nanozymes for Cancer Immunotherapy","volume":"18","author":"Zhang","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2026.115826_bib21","doi-asserted-by":"crossref","first-page":"103270","DOI":"10.1016\/j.mattod.2026.103270","article-title":"Precision uterine mRNA therapy to Restore implantation and fertility","volume":"95","author":"Liao","year":"2026","journal-title":"Mater. Today"},{"issue":"12","key":"10.1016\/j.colsurfb.2026.115826_bib22","first-page":"760","article-title":"STING: infection, inflammation and cancer, Nature reviews","volume":"15","author":"Barber","year":"2015","journal-title":"Immunology"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115826_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/vaccines13040371","article-title":"Progress Update on STING Agonists as Vaccine Adjuvants","volume":"13","author":"Shen","year":"2025","journal-title":"Vaccines"},{"issue":"11","key":"10.1016\/j.colsurfb.2026.115826_bib24","doi-asserted-by":"crossref","first-page":"95","DOI":"10.15698\/cst2023.11.291","article-title":"STING-driven activation of T cells: relevance for the adoptive cell therapy of cancer","volume":"7","author":"Richter","year":"2023","journal-title":"Cell Stress"},{"issue":"11","key":"10.1016\/j.colsurfb.2026.115826_bib25","doi-asserted-by":"crossref","first-page":"3074","DOI":"10.1016\/j.celrep.2018.11.047","article-title":"Magnitude of Therapeutic STING Activation Determines CD8(+) T Cell-Mediated Anti-tumor Immunity","volume":"25","author":"Sivick","year":"2018","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib26","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/med4.36","article-title":"Novel nanomaterials as photo\u2010activated cancer diagnostics and therapy","volume":"1","author":"Yadav","year":"2023","journal-title":"Med. Adv."},{"key":"10.1016\/j.colsurfb.2026.115826_bib27","article-title":"Clinical applications of STING agonists in cancer immunotherapy: current progress and future prospects","volume":"15","author":"Wang","year":"2024","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.colsurfb.2026.115826_bib28","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.7150\/ijbs.107837","article-title":"Identification of a Novel Small Molecule STING Agonist Reshaping the Immunomicroenvironment of Pancreatic Ductal Adenocarcinoma","volume":"21","author":"Liu","year":"2025","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/mco2.70001","article-title":"Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect","volume":"6","author":"Wang","year":"2025","journal-title":"MedComm"},{"issue":"12","key":"10.1016\/j.colsurfb.2026.115826_bib30","doi-asserted-by":"crossref","first-page":"10504","DOI":"10.1021\/jacs.4c18511","article-title":"Manganese-Driven Plasmid Nanofibers Formed In Situ for Cancer Gene Delivery and Metalloimmunotherapy","volume":"147","author":"Li","year":"2025","journal-title":"J. Am. Chem. Soc."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib31","doi-asserted-by":"crossref","first-page":"19","DOI":"10.21147\/j.issn.1000-9604.2023.01.04","article-title":"Mn-based cGAS-STING activation for tumor therapy","volume":"35","author":"Huang","year":"2023","journal-title":"Chin. J. Cancer Res"},{"key":"10.1016\/j.colsurfb.2026.115826_bib32","doi-asserted-by":"crossref","first-page":"124121","DOI":"10.1016\/j.biomaterials.2026.124121","article-title":"Engineering stem cell-based nanotherapeutics to overcome myocardial ischemia-reperfusion injury","author":"Li","year":"2026","journal-title":"Biomaterials"},{"issue":"46","key":"10.1016\/j.colsurfb.2026.115826_bib33","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202514085","article-title":"Emerging Nanozyme Strategies for Precision Breast Cancer Treatment","volume":"12","author":"Zang","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2026.115826_bib34","doi-asserted-by":"crossref","first-page":"114665","DOI":"10.1016\/j.jconrel.2026.114665","article-title":"Long-acting nanomedicine for brain diseases","author":"Liao","year":"2026","journal-title":"J. Control. Release"},{"issue":"5","key":"10.1016\/j.colsurfb.2026.115826_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.chempr.2026.103040","article-title":"Programming extracellular protein fate with peptide chimeras","volume":"12","author":"Liao","year":"2026","journal-title":"Chem"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115826_bib36","first-page":"677","article-title":"Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced\/Metastatic Solid Tumors or Lymphomas, Clinical cancer research: an official journal of the","volume":"28","author":"Meric-Bernstam","year":"2022","journal-title":"Am. Assoc. Cancer Res."},{"issue":"10","key":"10.1016\/j.colsurfb.2026.115826_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9103323","article-title":"Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy","volume":"9","author":"Motedayen Aval","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.colsurfb.2026.115826_bib38","doi-asserted-by":"crossref","first-page":"3113","DOI":"10.2147\/IJN.S497510","article-title":"Overcoming Biological Barriers in Cancer Therapy: Cell Membrane-Based Nanocarrier Strategies for Precision Delivery","volume":"20","author":"Li","year":"2025","journal-title":"Int. J. Nanomed."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib39","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/s41565-018-0342-5","article-title":"Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy","volume":"14","author":"Shae","year":"2019","journal-title":"Nat. Nanotechnol."},{"issue":"12","key":"10.1016\/j.colsurfb.2026.115826_bib40","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/s41577-021-00541-y","article-title":"Metabolic barriers to cancer immunotherapy","volume":"21","author":"DePeaux","year":"2021","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib41","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.cell.2019.05.003","article-title":"Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS","volume":"178","author":"Zhang","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.colsurfb.2026.115826_bib42","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.cytogfr.2025.06.002","article-title":"Metabolic Regulation of cGAS-STING Signaling in the Tumor Microenvironment: Dual Immune Roles and Therapeutic Implications","volume":"85","author":"Wu","year":"2025","journal-title":"Cytokine & Growth Factor Rev."},{"key":"10.1016\/j.colsurfb.2026.115826_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1563303","article-title":"Impact of lactate on immune cell function in the tumor microenvironment: mechanisms and therapeutic perspectives","volume":"16","author":"Gu","year":"2025","journal-title":"Front Immunol."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib44","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.immuni.2018.03.004","article-title":"Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape","volume":"48","author":"Wellenstein","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.colsurfb.2026.115826_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.copbio.2024.103105","article-title":"Delivery of STING agonists for cancer immunotherapy","volume":"87","author":"Wang","year":"2024","journal-title":"Curr. Opin. Biotechnol."},{"issue":"10","key":"10.1016\/j.colsurfb.2026.115826_bib46","doi-asserted-by":"crossref","first-page":"5216","DOI":"10.4049\/jimmunol.1300097","article-title":"Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid","volume":"190","author":"Conlon","year":"2013","journal-title":"Journal immunology (Baltimore Md. 1950)"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115826_bib47","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/s41419-023-05732-0","article-title":"Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells","volume":"14","author":"Li","year":"2023","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib48","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s11658-024-00623-4","article-title":"Triptolide-induced cuproptosis is a novel antitumor strategy for the treatment of cervical cancer","volume":"29","author":"Xiao","year":"2024","journal-title":"Cell Mol. Biol. Lett."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib49","article-title":"The cGAS\u2012STING pathway in cancer immunity: mechanisms, challenges, and therapeutic implications","volume":"18","author":"Shen","year":"2025","journal-title":"J. Hematol. & Oncol."},{"issue":"12","key":"10.1016\/j.colsurfb.2026.115826_bib50","doi-asserted-by":"crossref","first-page":"7262","DOI":"10.1021\/acs.molpharmaceut.5c01263","article-title":"Targeting the cGAS-STING Pathway for Cancer Immunotherapy: From Small-Molecule Agonists to Advanced Nanomaterials","volume":"22","author":"Guo","year":"2025","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.colsurfb.2026.115826_bib51","doi-asserted-by":"crossref","first-page":"123422","DOI":"10.1016\/j.biomaterials.2025.123422","article-title":"Recent advances in nanotechnology for repairing spinal cord injuries","volume":"323","author":"Li","year":"2025","journal-title":"Biomaterials"},{"issue":"9","key":"10.1016\/j.colsurfb.2026.115826_bib52","doi-asserted-by":"crossref","first-page":"3664","DOI":"10.1172\/JCI67230","article-title":"HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations","volume":"123","author":"Semenza","year":"2013","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.colsurfb.2026.115826_bib53","article-title":"Potential role of lactylation in intrinsic immune pathways in lung cancer","volume":"16","author":"Huang","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.colsurfb.2026.115826_bib54","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1146\/annurev-immunol-032712-100008","article-title":"Immunogenic cell death in cancer therapy","volume":"31","author":"Kroemer","year":"2013","journal-title":"Annu. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115826_bib55","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2019-000337","article-title":"Consensus guidelines for the definition, detection and interpretation of immunogenic cell death","volume":"8","author":"Galluzzi","year":"2020","journal-title":"J. Immunother. Cancer"},{"issue":"11","key":"10.1016\/j.colsurfb.2026.115826_bib56","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/s41565-023-01447-7","article-title":"Investigation of the enhanced antitumour potency of STING agonist after conjugation to polymer nanoparticles","volume":"18","author":"Dosta","year":"2023","journal-title":"Nat. Nanotechnol."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115826_bib57","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.apsb.2024.06.004","article-title":"Intravenous delivery of STING agonists using acid-sensitive polycationic polymer-modified lipid nanoparticles for enhanced tumor immunotherapy","volume":"15","author":"He","year":"2025","journal-title":"Acta Pharm. Sin. B"},{"issue":"43","key":"10.1016\/j.colsurfb.2026.115826_bib58","doi-asserted-by":"crossref","first-page":"29439","DOI":"10.1021\/acsnano.3c12337","article-title":"Robust and Sustained STING Pathway Activation via Hydrogel-Based In Situ Vaccination for Cancer Immunotherapy","volume":"18","author":"Cheng","year":"2024","journal-title":"ACS nano"},{"issue":"7","key":"10.1016\/j.colsurfb.2026.115826_bib59","doi-asserted-by":"crossref","DOI":"10.1093\/nsr\/nwae167","article-title":"STING agonist-conjugated metal-organic framework induces artificial leukocytoid structures and immune hotspots for systemic antitumor responses","volume":"11","author":"Luo","year":"2024","journal-title":"Natl. Sci. Rev."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526004145?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526004145?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T19:27:37Z","timestamp":1785785257000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776526004145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":59,"alternative-id":["S0927776526004145"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.115826","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A copper-engineered MnO\u2082 nanoplatform for potentiating STING activation and antitumor immunity in colorectal cancer","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.115826","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115826"}}