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Biosci."},{"key":"10.1016\/j.colsurfb.2026.115928_bib178","doi-asserted-by":"crossref","first-page":"107606","DOI":"10.1039\/C6RA20437F","article-title":"PTX encapsulated by an XG\u2013DOX conjugate for combination therapy against multi-drug resistance","volume":"6","author":"Huang","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.colsurfb.2026.115928_bib179","doi-asserted-by":"crossref","unstructured":"C. Huang, S. Ren, Y. Chen, PD-L1 methylation restricts PD-L1\/PD-1 interactions to control cancer immune surveillanceScience Advances9eade418610.1126\/sciadv.ade4186.","DOI":"10.1126\/sciadv.ade4186"},{"key":"10.1016\/j.colsurfb.2026.115928_bib180","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jconrel.2019.06.012","article-title":"Heat-activated drug delivery increases tumor accumulation of synergistic chemotherapies","volume":"308","author":"Dunne","year":"2019","journal-title":"J. Control. 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