{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T14:19:27Z","timestamp":1788531567771,"version":"build-2803163510"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006407","name":"Natural Science Foundation of Henan Province","doi-asserted-by":"publisher","award":["262300421278"],"award-info":[{"award-number":["262300421278"]}],"id":[{"id":"10.13039\/501100006407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006407","name":"Natural Science Foundation of Henan Province","doi-asserted-by":"publisher","award":["222300420002"],"award-info":[{"award-number":["222300420002"]}],"id":[{"id":"10.13039\/501100006407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.colsurfb.2026.115994","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T23:31:48Z","timestamp":1784244708000},"page":"115994","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P1","title":["TPGS incorporated solanesol-paclitaxel prodrug nanoparticles for synergic therapy of cancer"],"prefix":"10.1016","volume":"268","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4945-9492","authenticated-orcid":false,"given":"Junhui","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaojie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianlong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhou","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yabing","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2208-608X","authenticated-orcid":false,"given":"Shiyong","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.colsurfb.2026.115994_bib1","first-page":"209","article-title":"Conventional chemotherapy: millions of cures, unresolved therapeutic index","volume":"25","author":"Letai","year":"2025","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.colsurfb.2026.115994_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2025.101300","article-title":"Polymeric micellar paclitaxel, cisplatin, and tislelizumab as first-line therapy for advanced unresectable esophageal squamous cell carcinoma: A phase II study with resistance profiling in poor responders","volume":"84","author":"Liu","year":"2026","journal-title":"Drug. Resist. Updates"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115994_bib3","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1056\/NEJMoa2510308","article-title":"F. Investigators, Survival with Osimertinib plus Chemotherapy in EGFR-Mutated Advanced NSCLC","volume":"394","author":"Janne","year":"2026","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115994_bib4","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1001\/jama.2025.19400","article-title":"Peripheral Neuropathy: A Review","volume":"335","author":"Mauermann","year":"2026","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.colsurfb.2026.115994_bib5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.trecan.2025.11.008","article-title":"Chemotherapy-free cancer treatment - not for everyone yet","volume":"12","author":"Donze","year":"2026","journal-title":"Trends Cancer"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115994_bib6","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1001\/jamaoncol.2025.0001","article-title":"Efficacy of Hand Cooling and Compression in Preventing Taxane-Induced Neuropathy: The POLAR Randomized Clinical Trial","volume":"11","author":"Michel","year":"2025","journal-title":"JAMA Oncol."},{"issue":"14","key":"10.1016\/j.colsurfb.2026.115994_bib7","doi-asserted-by":"crossref","first-page":"11108","DOI":"10.1021\/acsnano.5c21452","article-title":"DNA Repair Enzyme Regulation Strategy for Enhanced Pancreatic Neuroendocrine Tumor Therapy via Targeting siRNA-Lipid Nanoparticles","volume":"20","author":"Wang","year":"2026","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2026.115994_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.jconrel.2025.113895","article-title":"Peptide-based nanoassembly enhances ferroptosis in cancer to overcome paclitaxel resistance","volume":"384","author":"Lin","year":"2025","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2026.115994_bib9","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.actbio.2025.02.012","article-title":"Proteolysis-targeting chimera-doxorubicin conjugate nanoassemblies for dual treatment of EGFR-TKI sensitive and resistant non-small cell lung cancer","volume":"195","author":"Ma","year":"2025","journal-title":"Acta Biomater."},{"key":"10.1016\/j.colsurfb.2026.115994_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2025.103606","article-title":"Unveiling the power of polymeric nanoparticles: Pioneering advances in breast cancer treatment","volume":"344","author":"Kumar","year":"2025","journal-title":"Adv. Colloid Interface Sci."},{"issue":"11","key":"10.1016\/j.colsurfb.2026.115994_bib11","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1038\/s41565-024-01754-7","article-title":"A translational framework to DELIVER nanomedicines to the clinic","volume":"19","author":"Joyce","year":"2024","journal-title":"Nat. Nanotechnol."},{"issue":"6","key":"10.1016\/j.colsurfb.2026.115994_bib12","doi-asserted-by":"crossref","first-page":"R238","DOI":"10.1016\/j.cub.2026.01.058","article-title":"Paclitaxel","volume":"36","author":"Zhang","year":"2026","journal-title":"Curr. Biol."},{"issue":"6","key":"10.1016\/j.colsurfb.2026.115994_bib13","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202517035","article-title":"Apoptosis-Amplified Intracellular Paclitaxel Nanoparticle Formation Enhances Microtubule Aggregation and PANoptosis","volume":"65","author":"Liu","year":"2026","journal-title":"Angew. Chem. Int. Ed. Engl."},{"issue":"6","key":"10.1016\/j.colsurfb.2026.115994_bib14","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/s41419-023-05869-y","article-title":"Nuclear complement C3b promotes paclitaxel resistance by assembling the SIN3A\/HDAC1\/2 complex in non-small cell lung cancer","volume":"14","author":"Wang","year":"2023","journal-title":"Cell. Death Dis."},{"key":"10.1016\/j.colsurfb.2026.115994_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2021.100754","article-title":"Therapeutic strategies to overcome taxane resistance in cancer","volume":"55","author":"Das","year":"2021","journal-title":"Drug. Resist. Updates"},{"issue":"Pt 1","key":"10.1016\/j.colsurfb.2026.115994_bib16","article-title":"Protein-based nanocarriers for paclitaxel (PTX) delivery in cancer treatment: A review","volume":"310","author":"Abbaspour","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"7","key":"10.1016\/j.colsurfb.2026.115994_bib17","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/s41565-021-00897-1","article-title":"Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer","volume":"16","author":"Li","year":"2021","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.colsurfb.2026.115994_bib18","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jconrel.2022.01.010","article-title":"Emerging nanomedicines of paclitaxel for cancer treatment","volume":"342","author":"Chen","year":"2022","journal-title":"J. Control. Release"},{"issue":"10","key":"10.1016\/j.colsurfb.2026.115994_bib19","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1038\/s43018-025-01029-7","article-title":"A sphingolipid-derived paclitaxel nanovesicle enhances efficacy of combination therapies in triple-negative breast cancer and pancreatic cancer","volume":"6","author":"Wang","year":"2025","journal-title":"Nat. Cancer"},{"key":"10.1016\/j.colsurfb.2026.115994_bib20","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.addr.2017.02.003","article-title":"The battle of \"nano\" paclitaxel","volume":"122","author":"Sofias","year":"2017","journal-title":"Adv. Drug. Deliv. Rev."},{"issue":"41","key":"10.1016\/j.colsurfb.2026.115994_bib21","doi-asserted-by":"crossref","first-page":"15040","DOI":"10.1021\/acs.nanolett.5c03911","article-title":"Hydrophobically Modified Paclitaxel Prodrug Enables Ultrahigh Drug Loading Driven by Polarity Redistribution","volume":"25","author":"Yang","year":"2025","journal-title":"Nano Lett."},{"key":"10.1016\/j.colsurfb.2026.115994_bib22","article-title":"A Topology-to-Therapy Map for Prodrug Nanoassemblies","author":"Li","year":"2026","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115994_bib23","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1021\/acs.nanolett.5c05756","article-title":"Hydrophobic\/Amphiphilic Prodrug Coassembly Strategy: Exploring the Effect of Oligoethylene Glycol Chains on the Antitumor Efficacy of Nanoassemblies","volume":"26","author":"Yuan","year":"2026","journal-title":"Nano Lett."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.115994_bib24","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1186\/s12951-025-03232-1","article-title":"ROS-responsive simvastatin nano-prodrug based on tertiary amine-oxide zwitterionic polymer for atherosclerotic therapy","volume":"23","author":"Yang","year":"2025","journal-title":"J. Nanobiotechnol."},{"issue":"23","key":"10.1016\/j.colsurfb.2026.115994_bib25","doi-asserted-by":"crossref","first-page":"33716","DOI":"10.1021\/acsami.5c07354","article-title":"Self-Assembling and Self-Immolative Three-in-One Prodrug Nanoassemblies for Self-Synergistic Combinational Anticancer Therapy","volume":"17","author":"Song","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.115994_bib26","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jcis.2024.09.096","article-title":"Dual role of triglyceride structures facilitates anti-tumor drug delivery: Both as a self-assembling module and a responsive module","volume":"678","author":"Zhong","year":"2025","journal-title":"J. Colloid Interface Sci."},{"issue":"12","key":"10.1016\/j.colsurfb.2026.115994_bib27","doi-asserted-by":"crossref","first-page":"14866","DOI":"10.1021\/acs.jmedchem.6c00971","article-title":"Self-Assembling Amphiphilic PROTACs: A Chemical Strategy for Improved EGFR-Targeted Protein Degradation","volume":"69","author":"Ma","year":"2026","journal-title":"J. Med. Chem."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115994_bib28","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1093\/annonc\/mdq438","article-title":"Phase 3 study of docosahexaenoic acid-paclitaxel versus dacarbazine in patients with metastatic malignant melanoma","volume":"22","author":"Bedikian","year":"2011","journal-title":"Ann. Oncol."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.115994_bib29","doi-asserted-by":"crossref","first-page":"3295","DOI":"10.1021\/acsnano.3c10037","article-title":"Tumor-Microenvironment-Activatable Nanoparticle Mediating Immunogene Therapy and M2 Macrophage-Targeted Inhibitor for Synergistic Cancer Immunotherapy","volume":"18","author":"Hu","year":"2024","journal-title":"ACS Nano"},{"issue":"44","key":"10.1016\/j.colsurfb.2026.115994_bib30","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202509183","article-title":"MitoSiege-Driven Catalase Collapse: A GSH-Responsive, Mitochondria-Targeted COF Prodrug for Amplified Chemodynamic Therapy","volume":"64","author":"Ding","year":"2025","journal-title":"Angew. Chem. Int. Ed. Engl."},{"issue":"20","key":"10.1016\/j.colsurfb.2026.115994_bib31","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202400109","article-title":"Folate-PEG-PROTAC Micelles for Enhancing Tumor-Specific Targeting Proteolysis In Vivo","volume":"13","author":"Ma","year":"2024","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.colsurfb.2026.115994_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2025.117273","article-title":"Sequential pH\/GSH-responsive stealth nanoparticles for co-delivery of anti-PD-1 antibody and paclitaxel to enhance chemoimmunotherapy of lung cancer","volume":"285","author":"Li","year":"2025","journal-title":"Eur. J. Med. Chem."},{"issue":"45","key":"10.1016\/j.colsurfb.2026.115994_bib33","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abc1725","article-title":"Trisulfide bond-mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity","volume":"6","author":"Yang","year":"2020","journal-title":"Sci. Adv."},{"issue":"10","key":"10.1016\/j.colsurfb.2026.115994_bib34","doi-asserted-by":"crossref","first-page":"5577","DOI":"10.1021\/nl502044x","article-title":"Disulfide Bond Bridge Insertion Turns Hydrophobic Anticancer Prodrugs into Self-Assembled Nanomedicines","volume":"14","author":"Wang","year":"2014","journal-title":"Nano Lett."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.115994_bib35","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1021\/acs.chemmater.1c03346","article-title":"Influence of Linkers within Stimuli-Responsive Prodrugs on Cancer Therapy: A Case of Five Doxorubicin Dimer-Based Nanoparticles","volume":"34","author":"Wang","year":"2022","journal-title":"Chem. Mater."},{"issue":"9","key":"10.1016\/j.colsurfb.2026.115994_bib36","doi-asserted-by":"crossref","first-page":"14591","DOI":"10.1021\/acsami.4c22621","article-title":"Natural Bioactive Compounds Solanesol and Chlorogenic Acid Assembled Nanomicelles for Alzheimer's Disease Therapy","volume":"17","author":"Wang","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.115994_bib37","article-title":"Integrated multi-omics unravels solanesol's multi-organ protection mechanisms against insulin resistance in type 2 diabetic mice","author":"Zhang","year":"2025","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.colsurfb.2026.115994_bib38","article-title":"Solanesol: a promising natural product","volume":"16","author":"Ma","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.colsurfb.2026.115994_bib39","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.actbio.2017.09.040","article-title":"mPEGylated solanesol micelles as redox-responsive nanocarriers with synergistic anticancer effect","volume":"64","author":"Qin","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.colsurfb.2026.115994_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2019.118823","article-title":"Solanesol derived therapeutic carriers for anticancer drug delivery","volume":"572","author":"Xiong","year":"2019","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2026.115994_bib41","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ijbiomac.2021.12.194","article-title":"Therapeutic carrier based on solanesol and hyaluronate for synergistic tumor treatment","volume":"201","author":"Zhang","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.colsurfb.2026.115994_bib42","doi-asserted-by":"crossref","DOI":"10.2991\/978-94-6239-703-3","article-title":"Boosting luteolin bioavailability via P-glycoprotein efflux inhibition: a self-microemulsifying drug delivery systems","author":"Zheng","year":"2026","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.colsurfb.2026.115994_bib43","doi-asserted-by":"crossref","first-page":"8529","DOI":"10.2147\/IJN.S517753","article-title":"Platelet Membrane-Coated Poly (Lactic-Co-Glycolic Acid) Nanoparticles as a Targeting Drug Delivery System for Multidrug-Resistant Breast Cancer","volume":"20","author":"Song","year":"2025","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2026.115994_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.jconrel.2025.113699","article-title":"Engineering stable prodrug self-assemblies by introducing the bromination effect","volume":"382","author":"Wang","year":"2025","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2026.115994_bib45","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.colsurfb.2015.03.040","article-title":"Reduction-sensitive micelles with sheddable PEG shells self-assembled from a Y-shaped amphiphilic polymer for intracellular doxorubicine release","volume":"129","author":"Cui","year":"2015","journal-title":"Colloid Surf. B."},{"key":"10.1016\/j.colsurfb.2026.115994_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2021.111914","article-title":"Progress in the study of D-alpha-tocopherol polyethylene glycol 1000 succinate (TPGS) reversing multidrug resistance","volume":"205","author":"Yan","year":"2021","journal-title":"Colloid Surf. B."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.115994_bib47","first-page":"729","article-title":"Ultrasound-enhanced fluorescence imaging and chemotherapy of multidrug-resistant tumors using multifunctional dendrimer\/carbon dot nanohybrids","volume":"6","author":"Li","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.colsurfb.2026.115994_bib48","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.actbio.2025.04.050","article-title":"PCL-PEtOx-based crystalline-core micelles for the targeted delivery of paclitaxel and trabectedin in ovarian cancer therapy","volume":"200","author":"Du","year":"2025","journal-title":"Acta Biomater."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526005825?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526005825?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T13:35:00Z","timestamp":1788528900000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776526005825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":48,"alternative-id":["S0927776526005825"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.115994","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TPGS incorporated solanesol-paclitaxel prodrug nanoparticles for synergic therapy of cancer","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.115994","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"115994"}}