{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:15:16Z","timestamp":1788552916441,"version":"build-2803163510"},"reference-count":237,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100018934","name":"Liaoning Provincial Department of Human Resources and Social Security","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018934","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Liaoning Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2025-MSLH-654"],"award-info":[{"award-number":["2025-MSLH-654"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.colsurfb.2026.116106","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T15:16:13Z","timestamp":1787411773000},"page":"116106","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P2","title":["Medicinal plant-derived carbon dots: Preparation strategies, functional properties, and biomedical applications"],"prefix":"10.1016","volume":"268","author":[{"given":"Wanshu","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximiao","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuaipeng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luming","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongying","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9293-5481","authenticated-orcid":false,"given":"Qinfu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2026.116106_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.146593","article-title":"Recent advances in carbon dots-based nanoplatforms: physicochemical properties and biomedical applications","volume":"476","author":"Rui","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"23","key":"10.1016\/j.colsurfb.2026.116106_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202300324","article-title":"Antibacterial carbon dots: mechanisms, design, and applications","volume":"12","author":"Zhao","year":"2023","journal-title":"Adv. Healthc. Mater."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib3","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202303773","article-title":"Multifunctional carbon dots for biomedical applications: diagnosis, therapy, and theranostic","volume":"20","author":"Wang","year":"2024","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2026.116106_bib4","article-title":"Antibacterial carbon dots","volume":"30","author":"Wang","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib5","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.matt.2021.10.016","article-title":"The light of carbon dots: From mechanism to applications","volume":"5","author":"Wang","year":"2022","journal-title":"Matter"},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116106_bib6","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1021\/acssensors.0c01556","article-title":"Recent Developments of Carbon Dots in Biosensing: A Review","volume":"5","author":"Ji","year":"2020","journal-title":"ACS Sens."},{"key":"10.1016\/j.colsurfb.2026.116106_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2025.115644","article-title":"Carbon dots in drug delivery and therapeutic applications","volume":"224","author":"Singh","year":"2025","journal-title":"Adv. Drug. Deliv. Rev."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116106_bib8","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1007\/s00604-026-08036-0","article-title":"\u03b2-Cyclodextrin-functionalized green-emissive carbon dots for supramolecular recognition and smartphone detection of major Alternaria mycotoxins in tomato paste","volume":"193","author":"Alaseem","year":"2026","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.colsurfb.2026.116106_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2026.117809","article-title":"Peroxidase-mimetic carbon dots enable dual-mode resveratrol detection via competitive hydroxyl radical scavenging","author":"Goda","year":"2026","journal-title":"Microchem. J."},{"key":"10.1016\/j.colsurfb.2026.116106_bib10","first-page":"1","article-title":"HOCl-Mediated Bromothymol Blue Bleaching and Carbon Dot Fluorescence Recovery for Fecal Myeloperoxidase Quantification in Ulcerative Colitis","author":"Alasiri","year":"2026","journal-title":"J. Fluoresc."},{"issue":"33","key":"10.1016\/j.colsurfb.2026.116106_bib11","doi-asserted-by":"crossref","first-page":"30676","DOI":"10.1039\/D6RA02905A","article-title":"Pharmacophore-targeted fluorescence sensing of ibrutinib via Michael addition-induced electron transfer on thiol-functionalized carbon dots","volume":"16","author":"Goda","year":"2026","journal-title":"RSC Adv."},{"issue":"21","key":"10.1016\/j.colsurfb.2026.116106_bib12","doi-asserted-by":"crossref","first-page":"4387","DOI":"10.1039\/D6AY00462H","article-title":"A novel peroxidase-mimicking Cu, S co-doped carbon dot nanozyme for dual-mode lactate biosensing in serum and sweat","volume":"18","author":"Alaseem","year":"2026","journal-title":"Anal. Methods"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib13","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/s41377-022-00798-5","article-title":"One step synthesis of efficient red emissive carbon dots and their bovine serum albumin composites with enhanced multi-photon fluorescence for in vivo bioimaging","volume":"11","author":"Zhang","year":"2022","journal-title":"Light Sci. Appl."},{"issue":"21","key":"10.1016\/j.colsurfb.2026.116106_bib14","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202201031","article-title":"Hydrothermal synthesis of high-yield red fluorescent carbon dots with ultra-narrow emission by controlled O\/N elements","volume":"34","author":"Xian","year":"2022","journal-title":"Adv. Mater."},{"issue":"15","key":"10.1016\/j.colsurfb.2026.116106_bib15","doi-asserted-by":"crossref","first-page":"18608","DOI":"10.1021\/acsami.2c21839","article-title":"Positively charged carbon dots with antibacterial and antioxidant dual activities for promoting infected wound healing","volume":"15","author":"Qu","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib16","doi-asserted-by":"crossref","DOI":"10.1002\/cmdc.202200479","article-title":"Emerging and versatile platforms of metal-ion-doped carbon dots for biosensing, bioimaging, and disease therapy","volume":"18","author":"Qian","year":"2023","journal-title":"ChemMedChem"},{"issue":"19","key":"10.1016\/j.colsurfb.2026.116106_bib17","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1016\/j.scib.2024.08.011","article-title":"Biomass-derived carbon dots with pharmacological activity for biomedicine: Recent advances and future perspectives","volume":"69","author":"Liu","year":"2024","journal-title":"Sci. Bull."},{"key":"10.1016\/j.colsurfb.2026.116106_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.117334","article-title":"The phytochemical and pharmacological profile of dandelion","volume":"179","author":"Yan","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.colsurfb.2026.116106_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.116086","article-title":"Research progress of Astragalus membranaceus in treating peritoneal metastatic cancer","volume":"305","author":"Li","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib20","article-title":"Honeysuckle extracts as a potential inhibitor of SARS-CoV-2 infection","volume":"16","author":"Lin","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"35","key":"10.1016\/j.colsurfb.2026.116106_bib21","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202403388","article-title":"Natural products from herbal medicine self-assemble into advanced bioactive materials","volume":"11","author":"Guo","year":"2024","journal-title":"Adv. Sci."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116106_bib22","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1016\/j.apsb.2023.02.005","article-title":"The traditional Chinese medicines treat chronic heart failure and their main bioactive constituents and mechanisms","volume":"13","author":"Chen","year":"2023","journal-title":"Acta Pharm. Sin. B"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib23","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s12951-024-02426-3","article-title":"Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023","volume":"22","author":"Ai","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib24","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jare.2024.01.034","article-title":"The future of plant based green carbon dots as cancer Nanomedicine: From current progress to future Perspectives and beyond","volume":"67","author":"Jing","year":"2025","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.colsurfb.2026.116106_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12951-021-01072-3","article-title":"Herbal medicine derived carbon dots: synthesis and applications in therapeutics, bioimaging and sensing","volume":"19","author":"Luo","year":"2021","journal-title":"J. Nanobiotechnol."},{"issue":"36","key":"10.1016\/j.colsurfb.2026.116106_bib26","doi-asserted-by":"crossref","first-page":"17356","DOI":"10.1021\/acsanm.5c03216","article-title":"Review of pharmacologically active carbon dots as versatile nanotherapeutics","volume":"8","author":"Wang","year":"2025","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.colsurfb.2026.116106_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2024.114392","article-title":"Low toxicity ginsenoside rg1-carbon nanodots as a potential therapeutic agent for human non-small cell lung cancer","volume":"246","author":"Wang","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"10","key":"10.1016\/j.colsurfb.2026.116106_bib28","doi-asserted-by":"crossref","first-page":"3393","DOI":"10.31557\/APJCP.2024.25.10.3393","article-title":"Medicinal Plants Derived Green Carbon Dots: Synthesis, Characterization and Their Potential Applications in Cancer Therapy","volume":"25","author":"Paveethra","year":"2024","journal-title":"Asian Pacific J. Cancer Prevention APJCP"},{"issue":"10","key":"10.1016\/j.colsurfb.2026.116106_bib29","doi-asserted-by":"crossref","first-page":"3984","DOI":"10.1021\/acsabm.3c00462","article-title":"Carbon Dots Derived from Traditional Chinese Medicines with Bioactivities: A Rising Star in Clinical Treatment","volume":"6","author":"Zhang","year":"2023","journal-title":"ACS Appl. Bio Mater."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib30","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s12951-023-02023-w","article-title":"Carbon nanodots constructed by ginsenosides and their high inhibitory effect on neuroblastoma","volume":"21","author":"Jiang","year":"2023","journal-title":"J. Nanobiotechnol."},{"issue":"6","key":"10.1016\/j.colsurfb.2026.116106_bib31","doi-asserted-by":"crossref","first-page":"9228","DOI":"10.1021\/acsnano.2c01619","article-title":"Carbon quantum dots-based nanozyme from coffee induces cancer cell ferroptosis to activate antitumor immunity","volume":"16","author":"Yao","year":"2022","journal-title":"ACS nano"},{"issue":"14","key":"10.1016\/j.colsurfb.2026.116106_bib32","doi-asserted-by":"crossref","first-page":"20885","DOI":"10.1021\/acsami.5c00635","article-title":"Photoresponsive Blood-Derived Protein Hydrogels Packed with Bioactive Carbon Dots Modulate Mitochondrial Homeostasis and Reprogram Metabolism for Chronic Wound Healing in Diabetes","volume":"17","author":"Ren","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib33","doi-asserted-by":"crossref","first-page":"10415","DOI":"10.2147\/IJN.S477587","article-title":"Yam Carbon Dots Promote Bone Defect Repair by Modulating Histone Demethylase 4B","author":"Chen","year":"2024","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2026.116106_bib34","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.2147\/IJN.S289515","article-title":"Protective effects of radix sophorae flavescentis carbonisata-based carbon dots against ethanol-induced acute gastric ulcer in rats: anti-inflammatory and antioxidant activities","author":"Hu","year":"2021","journal-title":"Int. J. Nanomed."},{"issue":"34","key":"10.1016\/j.colsurfb.2026.116106_bib35","doi-asserted-by":"crossref","first-page":"14426","DOI":"10.1039\/D1NR03999G","article-title":"Bioinspired Camellia japonica carbon dots with high near-infrared absorbance for efficient photothermal cancer therapy","volume":"13","author":"Kim","year":"2021","journal-title":"Nanoscale"},{"key":"10.1016\/j.colsurfb.2026.116106_bib36","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1016\/j.matpr.2020.04.195","article-title":"A facile approach for the synthesis of carbon dots from Hibiscus sabdariffa & its application as bio-imaging agent and Cr (VI) sensor","volume":"33","author":"Komalavalli","year":"2020","journal-title":"Mater. Today. Proc."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116106_bib37","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1039\/D4NR04486J","article-title":"Hawthorn carbon dots: a novel therapeutic agent for modulating body weight and hepatic lipid profiles in high-fat diet-fed mice","volume":"17","author":"Lin","year":"2025","journal-title":"Nanoscale"},{"issue":"17","key":"10.1016\/j.colsurfb.2026.116106_bib38","doi-asserted-by":"crossref","first-page":"20726","DOI":"10.1021\/acsami.3c01322","article-title":"Carbon dots from Lycium barbarum attenuate radiation-induced bone injury by inhibiting senescence via METTL3\/Clip3 in an m6A-dependent manner","volume":"15","author":"Guo","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib39","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.carbon.2023.03.039","article-title":"Green preparation of ginger-derived carbon dots accelerates wound healing","volume":"208","author":"Li","year":"2023","journal-title":"Carbon"},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib40","doi-asserted-by":"crossref","first-page":"242","DOI":"10.3390\/nano15030242","article-title":"Protective Effect of Carbon Dots Derived from Salvia miltiorrhiza Pretreatment in Acute Myocardial Infarction in Rats","volume":"15","author":"Dong","year":"2025","journal-title":"Nanomaterials"},{"key":"10.1016\/j.colsurfb.2026.116106_bib41","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.saa.2019.03.044","article-title":"Synthesis of nitrogen-doped graphene quantum dots (N-GQDs) from marigold for detection of Fe3+ ion and bioimaging","volume":"217","author":"Zhang","year":"2019","journal-title":"Spectrochim. Acta Part. A Mol. Biomol. Spectrosc."},{"issue":"29","key":"10.1016\/j.colsurfb.2026.116106_bib42","doi-asserted-by":"crossref","first-page":"34451","DOI":"10.1021\/acsami.3c04523","article-title":"Carbon dots from camelina decorating hFGF2-linked camelina lipid droplets cooperate to accelerate wound healing","volume":"15","author":"Zhang","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123967","article-title":"Kudzu root-derived carbon dots modulate gut microbiota and metabolites for pan-organ targeted macrophage polarization in synergistic diabetes therapy","volume":"329","author":"Yi","year":"2026","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2026.116106_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2023.113603","article-title":"Encapsulation of thymol and menthol loaded N\/S co-doped carbon dots derived from a mixture of herbal extracts as theranostic agents with anticancer properties","volume":"232","author":"Sattariazar","year":"2023","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib45","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1186\/s12951-024-02792-y","article-title":"A new strategy of using low-dose caffeic acid carbon nanodots for high resistance to poorly differentiated human papillary thyroid cancer","volume":"22","author":"Xin","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib46","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1039\/C7RA12069A","article-title":"Berberine-based carbon dots for selective and safe cancer theranostics","volume":"8","author":"Zhang","year":"2018","journal-title":"RSC Adv."},{"key":"10.1016\/j.colsurfb.2026.116106_bib47","doi-asserted-by":"crossref","first-page":"6249","DOI":"10.2147\/IJN.S176176","article-title":"Synthesis of ginsenoside Re-based carbon dots applied for bioimaging and effective inhibition of cancer cells","volume":"13","author":"Yao","year":"2018","journal-title":"Int. J. Nanomed."},{"issue":"41","key":"10.1016\/j.colsurfb.2026.116106_bib48","article-title":"High amplification of the antiviral activity of curcumin through transformation into carbon quantum dots","volume":"15","author":"Lin","year":"2019","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2026.116106_bib49","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.jpba.2018.11.025","article-title":"Ginkgo leaf-based synthesis of nitrogen-doped carbon quantum dots for highly sensitive detection of salazosulfapyridine in mouse plasma","volume":"164","author":"Jiang","year":"2019","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"7","key":"10.1016\/j.colsurfb.2026.116106_bib50","doi-asserted-by":"crossref","first-page":"8527","DOI":"10.1021\/acsami.3c18418","article-title":"Herbal medicine-inspired carbon quantum dots with antibiosis and hemostasis effects for promoting wound healing","volume":"16","author":"Zhu","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib51","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.2147\/IJN.S497892","article-title":"Eco-Friendly Synthesized Carbon Dots from Chinese Herbal Medicine: A Review","volume":"20","author":"Zhao","year":"2025","journal-title":"Int. J. Nanomed."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib52","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.chmed.2025.01.004","article-title":"Modernization of charcoal drugs: Integrating research paradigms of carbon dots to gain new perspectives","volume":"17","author":"Tian","year":"2025","journal-title":"Chin. Herbal. Med."},{"issue":"19","key":"10.1016\/j.colsurfb.2026.116106_bib53","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.2217\/nnm-2020-0472","article-title":"Gastroprotective effects of Nelumbinis Rhizomatis Nodus-derived carbon dots on ethanol-induced gastric ulcers in rats","volume":"16","author":"Luo","year":"2021","journal-title":"Nanomedicine"},{"issue":"6","key":"10.1016\/j.colsurfb.2026.116106_bib54","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1007\/s10895-023-03489-5","article-title":"Luminous insights: harnessing Carbon nanodots from black seed powder via pyrolysis for Bioimaging and Antifungal investigations","volume":"34","author":"Lad","year":"2024","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.colsurfb.2026.116106_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.162637","article-title":"Lophatherum-Gracile driven near-infrared carbon dots inhibit ferroptosis and mitophagy to treat acute kidney injury","volume":"513","author":"Yang","year":"2025","journal-title":"Chem. Eng. J."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib56","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-63700-w","article-title":"Heteroatom-doped carbon dots from medicinal plants as novel biomaterials for as-use biomedical applications in comparison with synthetic drug, zaltoprofen","volume":"14","author":"Kota","year":"2024","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib57","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-07780-2","article-title":"Therapeutic evaluation of Martynia annua derived carbon dots in epileptic Drosophila model","volume":"15","author":"Abbigeri","year":"2025","journal-title":"Sci. Rep."},{"issue":"118","key":"10.1016\/j.colsurfb.2026.116106_bib58","doi-asserted-by":"crossref","first-page":"97836","DOI":"10.1039\/C5RA16874K","article-title":"Theranostic carbon dots derived from garlic with efficient anti-oxidative effects towards macrophages","volume":"5","author":"Yang","year":"2015","journal-title":"RSC Adv."},{"issue":"31","key":"10.1016\/j.colsurfb.2026.116106_bib59","doi-asserted-by":"crossref","first-page":"17054","DOI":"10.1021\/acsami.5b03228","article-title":"Green synthesis of bifunctional fluorescent carbon dots from garlic for cellular imaging and free radical scavenging","volume":"7","author":"Zhao","year":"2015","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib60","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s13020-022-00625-4","article-title":"Traditional Chinese medicine syndrome differentiation and treatment by stages of Parkinson\u2019s disease: study protocol for a multicentre, randomized, double-blind, placebo-controlled clinical trial","volume":"17","author":"Hu","year":"2022","journal-title":"Chin. Med."},{"key":"10.1016\/j.colsurfb.2026.116106_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2025.114601","article-title":"Gardeniae Fructus derived natural small molecule-based carbon dots promoting activation and aggregation of platelets to accelerate hemostasis","volume":"251","author":"Zhang","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.145155","article-title":"Folate-targeted pH-sensitive albumin nanoparticles loaded with Baicalin enhance tamoxifen efficacy in estrogen receptor alpha-positive breast cancer","volume":"318","author":"Li","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"19","key":"10.1016\/j.colsurfb.2026.116106_bib63","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202304674","article-title":"Red\/NIR-I-Fluorescence Carbon Dots Based on Rhein with Active Oxygen Scavenging and Colitis Targeting for UC Therapeutics","volume":"13","author":"Xia","year":"2024","journal-title":"Adv. Healthc. Mater."},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116106_bib64","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1097\/CM9.0000000000003584","article-title":"Advancements in herbal medicine-based nanozymes for biomedical applications","volume":"138","author":"Yang","year":"2025","journal-title":"Chin. Med. J."},{"issue":"24","key":"10.1016\/j.colsurfb.2026.116106_bib65","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202418683","article-title":"Honeysuckle-Derived Carbon Dots With Robust Catalytic and Pharmacological Activities for Mitigating Lung Inflammation by Inhibition of Caspase11\/GSDMD-Dependent Pyroptosis","volume":"35","author":"Deng","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"27","key":"10.1016\/j.colsurfb.2026.116106_bib66","doi-asserted-by":"crossref","first-page":"24377","DOI":"10.1021\/acsnano.5c03934","article-title":"Carbon Dots as an Emergent Class of Sustainable Antifungal Agents","volume":"19","author":"Ghirardello","year":"2025","journal-title":"ACS nano"},{"issue":"46","key":"10.1016\/j.colsurfb.2026.116106_bib67","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202507840","article-title":"Small dots, multiple functions\u201d: unveiling the veil of a bioactive quercetin carbon dot and its multifaceted antibacterial and osteogenesis mechanisms for infectious bone defect repair","volume":"35","author":"Chen","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib68","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.7150\/thno.123141","article-title":"Pharmacologically inherited carbon dots from Salvia miltiorrhiza with potent antioxidant activity and multi-pathway modulation for myocardial ischemia-reperfusion injury therapy","volume":"16","author":"Zhang","year":"2026","journal-title":"Theranostics"},{"key":"10.1016\/j.colsurfb.2026.116106_bib69","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.142512","article-title":"Polysaccharide from Atractylodes macrocephala Koidz. alleviates pyrotinib-induced diarrhea through regulating cAMP\/LKB1\/AMPK\/CFTR pathway and restoring gut microbiota and metabolites","volume":"308","author":"Ran","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"30","key":"10.1016\/j.colsurfb.2026.116106_bib70","doi-asserted-by":"crossref","first-page":"42751","DOI":"10.1021\/acsami.5c08068","article-title":"Medicinal Plant-Derived Carbon Dots Nanozymes Ameliorate Ulcerative Colitis via Anti-inflammatory, Antioxidant, and Gut Barrier-Protective Effects","volume":"17","author":"Li","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib71","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s12951-023-01795-5","article-title":"Ultrasmall and highly biocompatible carbon dots derived from natural plant with amelioration against acute kidney injury","volume":"21","author":"Wang","year":"2023","journal-title":"J. Nanobiotechnol."},{"issue":"35","key":"10.1016\/j.colsurfb.2026.116106_bib72","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202503202","article-title":"Rapidly Gelling Sprayable Hydrogels Integrating Carbon Quantum Dots and Plant Extracellular Vesicles Enable Multifunctional Wound Care via Photothermal Management, Immunomodulation, and Ferroptosis","volume":"21","author":"Ding","year":"2025","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2026.116106_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.104795","article-title":"Nose to brain drug delivery - A promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion","volume":"159","author":"Long","year":"2020","journal-title":"Pharmacol. Res."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib74","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1186\/s12951-025-03406-x","article-title":"Oxidative stress induced paclitaxel-derived carbon dots inhibit glioblastoma proliferation and EMT process","volume":"23","author":"Yan","year":"2025","journal-title":"J. Nanobiotechnol."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib75","doi-asserted-by":"crossref","first-page":"422","DOI":"10.3390\/molecules30020422","article-title":"Epigynum auritum-Derived Near-Infrared Carbon Dots for Bioimaging and Antimicrobial Applications","volume":"30","author":"Shi","year":"2025","journal-title":"Molecules"},{"issue":"31","key":"10.1016\/j.colsurfb.2026.116106_bib76","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202500167","article-title":"Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines","volume":"12","author":"Li","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib77","article-title":"Bridging Traditional Chinese Medicine and Alzheimer's Disease: The Pivotal Role of Gut Microbiota in Multitarget Therapeutic Mechanisms","volume":"16","author":"Wu","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"12","key":"10.1016\/j.colsurfb.2026.116106_bib78","doi-asserted-by":"crossref","first-page":"18741","DOI":"10.1021\/acsami.4c22263","article-title":"Mulberry Leaves-Derived Carbon Dots for Photodynamic Treatment of Methicillin-Resistant Staphylococcus aureus-Infected Wounds via Metabolic Perturbation","volume":"17","author":"Chen","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"6","key":"10.1016\/j.colsurfb.2026.116106_bib79","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202403876","article-title":"Multifunctional carbon dots in situ confined hydrogel for optical communication, drug delivery, pH sensing, nanozymatic activity, and UV shielding applications","volume":"14","author":"Marvi","year":"2025","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.colsurfb.2026.116106_bib80","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2024.103182","article-title":"Biomass-derived carbon dots as significant biological tools in the medicinal field: A review","volume":"328","author":"Singh","year":"2024","journal-title":"Adv. Colloid Interface Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib81","article-title":"Emodin-Derived Red-Emissive Carbon Dots: Light-Driven ROS Generation and Antioxidant Activities in Non-Illuminative Regimes","volume":"324","author":"Jiang","year":"2025","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib82","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.3390\/molecules28041830","article-title":"Glycyrrhizae radix et rhizoma-derived carbon dots and their effect on menopause syndrome in ovariectomized mice","volume":"28","author":"Zhang","year":"2023","journal-title":"Molecules"},{"issue":"8","key":"10.1016\/j.colsurfb.2026.116106_bib83","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1080\/21691401.2017.1379015","article-title":"Novel carbon dots derived from Schizonepetae Herba Carbonisata and investigation of their haemostatic efficacy","volume":"46","author":"Zhang","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"sup3","key":"10.1016\/j.colsurfb.2026.116106_bib84","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1080\/21691401.2018.1492419","article-title":"Haemostatic bioactivity of novel Schizonepetae Spica Carbonisata-derived carbon dots via platelet counts elevation","volume":"46","author":"Sun","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib85","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1021\/acsabm.3c00575","article-title":"Functionalized phytochemicals-embedded carbon dots derived from medicinal plant for bioimaging application","volume":"7","author":"Annisa","year":"2023","journal-title":"ACS Appl. Bio Mater."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib86","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-78745-0","article-title":"Green synthesis of fluorescent N-doped carbon quantum dots from castor seeds and their applications in cell imaging and pH sensing","volume":"14","author":"Elkun","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.colsurfb.2026.116106_bib87","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2024.108656","article-title":"Bibliometric analysis of research progress on tetramethylpyrazine and its effects on ischemia-reperfusion injury","volume":"259","author":"Qi","year":"2024","journal-title":"Pharmacol. Ther."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib88","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1186\/s12951-025-03477-w","article-title":"Carbon dots derived from Ligusticum Chuanxiong mitigate cardiac injury by disrupting the harmful oxidative stress-apoptosis cycle","volume":"23","author":"Guo","year":"2025","journal-title":"J. Nanobiotechnol."},{"issue":"18","key":"10.1016\/j.colsurfb.2026.116106_bib89","doi-asserted-by":"crossref","first-page":"17287","DOI":"10.1021\/acsnano.4c14373","article-title":"Reactive Oxygen Species-Responsive Polymer Drug Delivery System Targeted Oxidative Stressed Colon Cells to Ameliorate Colitis","volume":"19","author":"Cai","year":"2025","journal-title":"ACS nano"},{"issue":"13","key":"10.1016\/j.colsurfb.2026.116106_bib90","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.1039\/D4TB02364A","article-title":"Surface moieties drive the superior protection of curcumin-derived carbon quantum dots against retinal ischemia-reperfusion injury","volume":"13","author":"Sun","year":"2025","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.colsurfb.2026.116106_bib91","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.aej.2024.02.041","article-title":"Formulation and evaluation of anti-osteoarthritic, cytotoxicity and antioxidant effects of carbon dots derived Allium sativum L. leaf extract","volume":"92","author":"He","year":"2024","journal-title":"Alex. Eng. J."},{"key":"10.1016\/j.colsurfb.2026.116106_bib92","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2025.217677","article-title":"Anti-SARS-CoV-2 and anticancer properties of triptolide and its derived carbonized nanomaterials","volume":"619","author":"Kousar","year":"2025","journal-title":"Cancer Lett."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib93","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3390\/nano9020199","article-title":"Biocompatibility and bioimaging potential of fruit-based carbon dots","volume":"9","author":"Dias","year":"2019","journal-title":"Nanomaterials"},{"key":"10.1016\/j.colsurfb.2026.116106_bib94","article-title":"Se\/S co-doped onion-derived CDs synergistically treat AKI by alleviating oxidative stress and enhancing iron chelation","author":"Liu","year":"2026","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib95","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.jcis.2020.05.005","article-title":"Direct conjugation of distinct carbon dots as Lego-like building blocks for the assembly of versatile drug nanocarriers","volume":"576","author":"Zhou","year":"2020","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120106","article-title":"Biodegradable poly (\u03b3-glutamic acid)@ glucose oxidase@ carbon dot nanoparticles for simultaneous multimodal imaging and synergetic cancer therapy","volume":"252","author":"Zhang","year":"2020","journal-title":"Biomaterials"},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116106_bib97","doi-asserted-by":"crossref","first-page":"420","DOI":"10.3390\/jof8050420","article-title":"Transcriptomics integrated with metabolomics reveals 2-Methoxy-1, 4-naphthoquinone-based carbon dots induced molecular shifts in Penicillium italicum","volume":"8","author":"Chen","year":"2022","journal-title":"J. Fungi"},{"issue":"16","key":"10.1016\/j.colsurfb.2026.116106_bib98","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202000607","article-title":"Nucleolus-Targeted photodynamic anticancer therapy using renal-clearable carbon dots","volume":"9","author":"Pang","year":"2020","journal-title":"Adv. Healthc. Mater."},{"issue":"6","key":"10.1016\/j.colsurfb.2026.116106_bib99","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/bio.3801","article-title":"Highly fluorescent carbon dots from wheat bran as a novel drug delivery system for bacterial inhibition","volume":"35","author":"John","year":"2020","journal-title":"Luminescence"},{"key":"10.1016\/j.colsurfb.2026.116106_bib100","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.126935","article-title":"Preparation of highly crystalline nitrogen-doped carbon dots and their application in sequential fluorescent detection of Fe3+ and ascorbic acid","volume":"326","author":"Lv","year":"2020","journal-title":"Food Chem."},{"key":"10.1016\/j.colsurfb.2026.116106_bib101","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2020.120943","article-title":"Facile synthesis of ratiometric fluorescent carbon dots for pH visual sensing and cellular imaging","volume":"216","author":"Guo","year":"2020","journal-title":"Talanta"},{"key":"10.1016\/j.colsurfb.2026.116106_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.mtbio.2025.102018","article-title":"Red-emissive carbon dot-cobalt oxyhydroxide nanosystem: A turn-on sensor for \u03b1-Glucosidase activity and inhibitor identification","author":"Sun","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib103","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s12951-017-0296-z","article-title":"Hemostatic bioactivity of novel Pollen Typhae Carbonisata-derived carbon quantum dots","volume":"15","author":"Yan","year":"2017","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.diamond.2025.112075","article-title":"Curcumin-derived water-soluble carbon dots without detectable resistance: Dual potentials for antimicrobial activity and infected wound healing","volume":"153","author":"Du","year":"2025","journal-title":"Diam. Relat. Mater."},{"issue":"28","key":"10.1016\/j.colsurfb.2026.116106_bib105","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.2174\/0113816128353103250116112919","article-title":"Green synthesis of curcumin loaded carbon dots as a sustained drug delivery for anticancer therapy","volume":"31","author":"Saini","year":"2025","journal-title":"Curr. Pharm. Des."},{"issue":"33","key":"10.1016\/j.colsurfb.2026.116106_bib106","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202503883","article-title":"Near-Infrared Afterglow Imaging-Guided Surgical Resection and Synergistic Photodynamic-Chemo Therapy of Breast Cancer","volume":"12","author":"Li","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib107","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.1038\/s41401-025-01578-8","article-title":"Norcantharidin promotes M1 macrophage polarization and suppresses colorectal cancer growth","volume":"46","author":"Wei","year":"2025","journal-title":"Acta Pharmacol. Sin."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib108","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s12951-020-00677-4","article-title":"Synergistic co-delivery of diacid metabolite of norcantharidin and ABT-737 based on folate-modified lipid bilayer-coated mesoporous silica nanoparticle against hepatic carcinoma","volume":"18","author":"Liu","year":"2020","journal-title":"J. Nanobiotechnol."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib109","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1186\/s12951-022-01703-3","article-title":"Review targeted drug delivery systems for norcantharidin in cancer therapy","volume":"20","author":"Zhai","year":"2022","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib110","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2020.111285","article-title":"Enhanced anticancer efficacy of cantharidin by mPEG-PLGA micellar encapsulation: An effective strategy for application of a poisonous traditional Chinese medicine","volume":"196","author":"Yao","year":"2020","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"32","key":"10.1016\/j.colsurfb.2026.116106_bib111","doi-asserted-by":"crossref","first-page":"38653","DOI":"10.1021\/acsami.3c06188","article-title":"Carbon quantum dots derived from herbal medicine as therapeutic nanoagents for rheumatoid arthritis with ultrahigh lubrication and anti-inflammation","volume":"15","author":"Qiang","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib112","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1186\/s12951-025-03494-9","article-title":"Carbon dots from purple sweet potato as a promising anti-inflammatory biomaterial for alleviating the LPS-induced inflammation in macrophages","volume":"23","author":"Jiang","year":"2025","journal-title":"J. Nanobiotechnol."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib113","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.chmed.2024.07.006","article-title":"Research and utilization status of Lophatherum gracile: A medicinal and food homologous plant","volume":"17","author":"Yao","year":"2025","journal-title":"Chin. Herbal. Med."},{"key":"10.1016\/j.colsurfb.2026.116106_bib114","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.137336","article-title":"In vitro digestibility and hepato-protective potential of Lophatherum gracile Brongn. leave extract","volume":"433","author":"Ma","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.colsurfb.2026.116106_bib115","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113224","article-title":"Lophatherum gracile Brongn. attenuates neutrophilic inflammation through inhibition of JNK and calcium","volume":"264","author":"Lai","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib116","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jhip.2025.06.007","article-title":"The ameliorative effects of honeysuckle extract and its major component luteolin on autism-like behaviors in the NDE1 deficiency model","volume":"6","author":"Zhang","year":"2025","journal-title":"J. Holist. Integr. Pharm."},{"key":"10.1016\/j.colsurfb.2026.116106_bib117","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2025.114609","article-title":"Quercetin-derived carbon dots promote proliferation and migration of Schwann cells and enhance neurite outgrowth","volume":"251","author":"Kasi","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib118","article-title":"Curcumin-alendronate carbon dots: A dual-logic strategy for precision treatment of periodontitis","volume":"33","author":"Zhang","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116106_bib119","doi-asserted-by":"crossref","first-page":"3519","DOI":"10.1007\/s10895-024-03790-x","article-title":"Citrus medica-derived fluorescent carbon Dots for the imaging of vigna radiate root cells","volume":"35","author":"Varghese","year":"2025","journal-title":"J. Fluoresc."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib120","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1186\/s12951-025-03497-6","article-title":"N-doped carbon dots for dual-modality NIR fluorescence imaging and photothermal therapy","volume":"23","author":"Shi","year":"2025","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib121","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.msec.2017.05.090","article-title":"Synthesis and cell imaging applications of amphiphilic AIE-active poly (amino acid) s","volume":"79","author":"Tian","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib122","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/s41392-023-01642-x","article-title":"Smart nanoparticles for cancer therapy","volume":"8","author":"Sun","year":"2023","journal-title":"Signal. Transduct. Target. Ther."},{"key":"10.1016\/j.colsurfb.2026.116106_bib123","first-page":"174","article-title":"Tumor diagnosis using carbon-based quantum dots: Detection based on the hallmarks of cancer","volume":"33","author":"Wang","year":"2024","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.colsurfb.2026.116106_bib124","article-title":"Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain","author":"Feng","year":"2025","journal-title":"Adv. Mater."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib125","article-title":"Recent advances of fluorescent carbon dots for biological imaging and biosensing","volume":"519","author":"Bian","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2026.116106_bib126","doi-asserted-by":"crossref","DOI":"10.1016\/j.diamond.2023.110121","article-title":"Poria cocos-derived carbon dots for cellular imaging, free radical scavenging and pH sensing","volume":"137","author":"Yuan","year":"2023","journal-title":"Diam. Relat. Mater."},{"issue":"6","key":"10.1016\/j.colsurfb.2026.116106_bib127","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1021\/acsabm.4c00249","article-title":"Dopamine-Functionalized, Red Carbon Quantum Dots for In Vivo Bioimaging, Cancer Therapeutics, and Neuronal Differentiation","volume":"7","author":"Yadav","year":"2024","journal-title":"ACS Appl. Bio Mater."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib128","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1007\/s00604-025-07100-5","article-title":"Targeted bio-imaging in discriminating normal and cancerous cells using dual-doped carbon dots derived from Dahlia pinnata flower extract","volume":"192","author":"Dhanush","year":"2025","journal-title":"Microchim. Acta"},{"issue":"67","key":"10.1016\/j.colsurfb.2026.116106_bib129","doi-asserted-by":"crossref","first-page":"38376","DOI":"10.1039\/C8RA07944G","article-title":"Bamboo leaf-based carbon dots for efficient tumor imaging and therapy","volume":"8","author":"Fahmi","year":"2018","journal-title":"RSC Adv."},{"key":"10.1016\/j.colsurfb.2026.116106_bib130","article-title":"A sustainable synthesis of green carbon quantum dot (CQD) from Catharanthus roseus (white flowering plant) leaves and investigation of its dual fluorescence responsive behavior in multi-ion detection and biological applications","volume":"23","author":"Arumugham","year":"2020","journal-title":"Sustain. Mater. Technol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib131","article-title":"Solvent assisted regulation of the properties of Sanguisorba officinalis L. derived carbon dots: Application in antioxidant, fluorescence imaging and fluorescence detection","author":"Lan","year":"2025","journal-title":"Mater. Res. Bull."},{"issue":"30","key":"10.1016\/j.colsurfb.2026.116106_bib132","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202401513","article-title":"Advance of Near-Infrared Emissive Carbon Dots in Diagnosis and Therapy: Synthesis, Luminescence, and Application","volume":"13","author":"Hu","year":"2024","journal-title":"Adv. Healthc. Mater."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib133","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1038\/s41467-024-46668-z","article-title":"Photooxidation triggered ultralong afterglow in carbon nanodots","volume":"15","author":"Zheng","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.colsurfb.2026.116106_bib134","article-title":"Reprogramming Tumor Cell Death via Processing Natural Drug to Carbon Dots Overcomes Collagen Barrier and Activates Antitumor Immunity","author":"Yan","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib135","doi-asserted-by":"crossref","first-page":"6349","DOI":"10.1038\/s41467-024-50688-0","article-title":"Imaging-guided companion diagnostics in radiotherapy by monitoring APE1 activity with afterglow and MRI imaging","volume":"15","author":"Yue","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.colsurfb.2026.116106_bib136","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlumin.2023.119692","article-title":"Turmeric-derived gadolinium-doped carbon quantum dots for multifunctional fluorescence imaging and MRI contrast agent","volume":"257","author":"Molaei","year":"2023","journal-title":"J. Lumin."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib137","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1002\/jbm.b.34508","article-title":"Manganese-doped green tea-derived carbon quantum dots as a targeted dual imaging and photodynamic therapy platform","volume":"108","author":"Irmania","year":"2020","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater."},{"issue":"7","key":"10.1016\/j.colsurfb.2026.116106_bib138","doi-asserted-by":"crossref","first-page":"587","DOI":"10.2217\/nnm-2020-0424","article-title":"Applications of natural product-derived carbon dots in cancer biology","volume":"16","author":"Naik","year":"2021","journal-title":"Nanomedicine"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib139","doi-asserted-by":"crossref","first-page":"5797","DOI":"10.1038\/s41467-022-33598-x","article-title":"Chemotherapy-induced complement signaling modulates immunosuppression and metastatic relapse in breast cancer","volume":"13","author":"Monteran","year":"2022","journal-title":"Nat. Commun."},{"issue":"8","key":"10.1016\/j.colsurfb.2026.116106_bib140","doi-asserted-by":"crossref","first-page":"4873","DOI":"10.1021\/acsabm.0c00377","article-title":"Solvent-free synthesis of fluorescent carbon dots: an ecofriendly approach for the bioimaging and screening of anticancer activity via caspase-induced apoptosis","volume":"3","author":"Ankireddy","year":"2020","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.colsurfb.2026.116106_bib141","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.ijleo.2017.12.200","article-title":"Synthesis of fluorescent carbon dots using Daucus carota subsp. sativus roots for mitomycin drug delivery","volume":"158","author":"D\u2019souza","year":"2018","journal-title":"Optik"},{"key":"10.1016\/j.colsurfb.2026.116106_bib142","article-title":"Rhodium-based metallodrugs for biological applications: current status and future perspectives","volume":"33","author":"Xiang","year":"2025","journal-title":"Mater. Today Bio"},{"key":"10.1016\/j.colsurfb.2026.116106_bib143","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioadv.2023.213561","article-title":"Green nanoarchitectonics of carbon quantum dots from Cinchona pubescens Vahl as targeted and controlled drug cancer nanocarrier","volume":"153","author":"Gonz\u00e1lez-Reyna","year":"2023","journal-title":"Biomater. Adv."},{"key":"10.1016\/j.colsurfb.2026.116106_bib144","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jcis.2023.02.041","article-title":"Degradable iron-rich mesoporous dopamine as a dual-glutathione depletion nanoplatform for photothermal-enhanced ferroptosis and chemodynamic therapy","volume":"639","author":"Cheng","year":"2023","journal-title":"J. Colloid Interface Sci."},{"issue":"38","key":"10.1016\/j.colsurfb.2026.116106_bib145","doi-asserted-by":"crossref","first-page":"34573","DOI":"10.1021\/acsomega.2c04484","article-title":"Green synthesis of near-infrared copper-doped carbon dots from alcea for cancer photothermal therapy","volume":"7","author":"Najaflu","year":"2022","journal-title":"ACS Omega"},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib146","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/s41565-021-01051-7","article-title":"A multifunctional chemical toolbox to engineer carbon dots for biomedical and energy applications","volume":"17","author":"\u00d0or\u0111evi\u0107","year":"2022","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib147","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.actbio.2022.06.001","article-title":"Biomimetic smart mesoporous carbon nanozyme as a dual-GSH depletion agent and O2 generator for enhanced photodynamic therapy","volume":"148","author":"Lu","year":"2022","journal-title":"Acta Biomater."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib148","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2023.108946","article-title":"Lysosome-targeted carbon dots with a light-controlled nitric oxide releasing property for enhanced photodynamic therapy","volume":"35","author":"Cai","year":"2024","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.colsurfb.2026.116106_bib149","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jconrel.2019.12.042","article-title":"Mesoporous carbon\u2011manganese nanocomposite for multiple imaging guided oxygen-elevated synergetic therapy","volume":"319","author":"Li","year":"2020","journal-title":"J. Control. Release"},{"issue":"31","key":"10.1016\/j.colsurfb.2026.116106_bib150","doi-asserted-by":"crossref","first-page":"12234","DOI":"10.1039\/D3SC07006A","article-title":"Recent advances for enhanced photodynamic therapy: from new mechanisms to innovative strategies","volume":"15","author":"Wang","year":"2024","journal-title":"Chem. Sci."},{"issue":"15","key":"10.1016\/j.colsurfb.2026.116106_bib151","doi-asserted-by":"crossref","first-page":"7025","DOI":"10.1039\/D1CS01079D","article-title":"New guidelines and definitions for type I photodynamic therapy","volume":"54","author":"Li","year":"2025","journal-title":"Chem. Soc. Rev."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib152","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s12951-024-02479-4","article-title":"Carbon dots as a novel photosensitizer for photodynamic therapy of cancer and bacterial infectious diseases: recent advances","volume":"22","author":"Sun","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib153","doi-asserted-by":"crossref","first-page":"7893","DOI":"10.2147\/IJN.S507574","article-title":"Antibacterial and Antitumor Application of Carbon Dots Based on Natural Products for Photodynamic\/Photothermal Effects","volume":"20","author":"Romero","year":"2025","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2026.116106_bib154","article-title":"Red fluorescent carbon dots for tumor imaging and photodynamic-enzyme catalyzed combined therapy","author":"Hou","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"31","key":"10.1016\/j.colsurfb.2026.116106_bib155","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202206683","article-title":"Carbon Dots and Tumor Antigen Conjugates as Nanovaccines for Elevated Cancer Immunotherapy","volume":"19","author":"Liu","year":"2023","journal-title":"Small"},{"issue":"7","key":"10.1016\/j.colsurfb.2026.116106_bib156","doi-asserted-by":"crossref","first-page":"7942","DOI":"10.1021\/acsanm.4c00546","article-title":"Copper-doped luteolin carbon dots with antitumor properties based on the induction of immunogenic cell death","volume":"7","author":"Zhang","year":"2024","journal-title":"ACS Appl. Nano Mater."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib157","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1016\/j.apsb.2023.12.008","article-title":"Nano-formulated delivery of active ingredients from traditional Chinese herbal medicines for cancer immunotherapy","volume":"14","author":"Shang","year":"2024","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.colsurfb.2026.116106_bib158","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.125788","article-title":"Synthesis and characterization of chitosan\/carbon quantum dots\/Fe2O3 nanocomposite comprising curcumin for targeted drug delivery in breast cancer therapy","volume":"249","author":"Zoghi","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib159","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216332","article-title":"Curcumin in cancer therapy: Exploring molecular mechanisms and overcoming clinical challenges","volume":"570","author":"Wang","year":"2023","journal-title":"Cancer Lett."},{"key":"10.1016\/j.colsurfb.2026.116106_bib160","article-title":"Curcumin derived functional carbon quantum dots for enhanced tumor theranostic","volume":"508","author":"Zhang","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2026.116106_bib161","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2022.119628","article-title":"Starch-based carriers of paclitaxel: A systematic review of carriers, interactions, and mechanisms","volume":"291","author":"Zhao","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.colsurfb.2026.116106_bib162","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113413","article-title":"Application of nanotechnology to herbal antioxidants as improved phytomedicine: An expanding horizon","volume":"153","author":"Mishra","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"16","key":"10.1016\/j.colsurfb.2026.116106_bib163","doi-asserted-by":"crossref","first-page":"15189","DOI":"10.1021\/acsnano.5c00700","article-title":"Stimuli-Responsive Nanomedicines for the Treatment of Non-cancer Related Inflammatory Diseases","volume":"19","author":"Yang","year":"2025","journal-title":"ACS Nano"},{"issue":"11","key":"10.1016\/j.colsurfb.2026.116106_bib164","doi-asserted-by":"crossref","first-page":"3873","DOI":"10.1039\/D2CS00172A","article-title":"Recent progress in the development of fluorescent probes for imaging pathological oxidative stress","volume":"52","author":"Geng","year":"2023","journal-title":"Chem. Soc. Rev."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib165","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/s41467-023-35828-2","article-title":"Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme","volume":"14","author":"Gao","year":"2023","journal-title":"Nat. Commun."},{"issue":"33","key":"10.1016\/j.colsurfb.2026.116106_bib166","doi-asserted-by":"crossref","first-page":"22055","DOI":"10.1021\/acsnano.4c05266","article-title":"Structurally oriented carbon dots as ROS nanomodulators for dynamic chronic inflammation and infection elimination","volume":"18","author":"Nie","year":"2024","journal-title":"ACS nano"},{"key":"10.1016\/j.colsurfb.2026.116106_bib167","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2026.176544","article-title":"Chrysanthemum-derived carbon dots alleviate colitis by dual targeting and regulating Keap1\/Nrf2 and NF-\u03baB\/NLRP3 signaling pathways","volume":"537","author":"Ma","year":"2026","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2026.116106_bib168","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.157433","article-title":"Dracocephalum moldavica L.-derived carbon dots for effective periodontitis treatment via reprogramming energy metabolism in macrophages","volume":"501","author":"Zhang","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib169","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/ame2.12224","article-title":"Classic mechanisms and experimental models for the anti-inflammatory effect of traditional Chinese medicine","volume":"5","author":"Hongzhi","year":"2022","journal-title":"Anim. Model. Exp. Med."},{"key":"10.1016\/j.colsurfb.2026.116106_bib170","doi-asserted-by":"crossref","DOI":"10.5772\/intechopen.1007252","article-title":"Recent advances in antioxidant carbon dots for biomedical applications","author":"Zhou","year":"2026","journal-title":"Progress. Mater. Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib171","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110015","article-title":"Geniposide alleviates atherosclerosis by regulating macrophage polarization via the FOS\/MAPK signaling pathway","volume":"125","author":"Jin","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.colsurfb.2026.116106_bib172","doi-asserted-by":"crossref","DOI":"10.1093\/burnst\/tkac046","article-title":"Puerarin improves diabetic wound healing via regulation of macrophage M2 polarization phenotype","volume":"10","author":"Li","year":"2022","journal-title":"Burns Trauma."},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116106_bib173","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1111\/bph.15773","article-title":"Rhein regulates redox-mediated activation of NLRP3 inflammasomes in intestinal inflammation through macrophage-activated crosstalk","volume":"179","author":"Zhou","year":"2022","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib174","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.117838","article-title":"Traditional Chinese medicine in regulating macrophage polarization in immune response of inflammatory diseases","volume":"325","author":"Chen","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib175","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2023.115140","article-title":"Vaccines for immune tolerance against autoimmune disease","volume":"203","author":"Kim","year":"2023","journal-title":"Adv. Drug. Deliv. Rev."},{"key":"10.1016\/j.colsurfb.2026.116106_bib176","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1390351","article-title":"The emerging role of oxidative stress in inflammatory bowel disease","volume":"15","author":"Muro","year":"2024","journal-title":"Front. Endocrinol."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib177","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/pcmedi\/pbab025","article-title":"Dichotomous roles of neutrophils in modulating pathogenic and repair processes of inflammatory bowel diseases","volume":"4","author":"Chen","year":"2021","journal-title":"Precis. Clin. Med."},{"key":"10.1016\/j.colsurfb.2026.116106_bib178","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2026.121176","article-title":"Ethyl acetate fraction from Dendrobium officinale inhibits IL-17A signaling pathway to mitigate acute lung injury","volume":"360","author":"Zhu","year":"2026","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib179","article-title":"Key toxicological targets identification for atherosclerosis induced by environmental hazardous substance nicotine exposure and its antagonists screening from active components of Dendrobium officinale","volume":"501","author":"Li","year":"2025","journal-title":"J. Hazard. Mater."},{"issue":"44","key":"10.1016\/j.colsurfb.2026.116106_bib180","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202512567","article-title":"Dendrobium Officinale-Derived Carbon Dots Nanozymes Alleviate Colitis by Orchestrating Intestinal Mucus-Epithelium-Immune Barriers","volume":"12","author":"Xu","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib181","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157106","article-title":"Mitochondrial pathways in rheumatoid arthritis: therapeutic roles of traditional Chinese medicine and natural products","volume":"146","author":"Li","year":"2025","journal-title":"Phytomedicine"},{"key":"10.1016\/j.colsurfb.2026.116106_bib182","article-title":"Functionalized carbon nano onion as a novel drug delivery system for brain targeting","volume":"63","author":"Majumder","year":"2021","journal-title":"J. Drug. Deliv. Sci. Technol."},{"key":"10.1016\/j.colsurfb.2026.116106_bib183","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2025.102876","article-title":"Quantum Dots in Neurotheranostics for the Treatment of Alzheimer\u2019s Disease","volume":"112","author":"Sharma","year":"2025","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.colsurfb.2026.116106_bib184","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.139724","article-title":"Exosomes-encapsulated biomimetic polydopamine carbon dots with dual-targeting effect alleviate motor and non-motor symptoms of Parkinson's disease via anti-neuroinflammation","volume":"296","author":"Yang","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"13","key":"10.1016\/j.colsurfb.2026.116106_bib185","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1039\/D1NA00145K","article-title":"Crossing the blood\u2013brain barrier with carbon dots: uptake mechanism and in vivo cargo delivery","volume":"3","author":"Seven","year":"2021","journal-title":"Nanoscale Adv."},{"key":"10.1016\/j.colsurfb.2026.116106_bib186","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.115406","article-title":"Exploring the therapeutic potential of natural compounds for Alzheimer's disease: Mechanisms of action and pharmacological properties","volume":"166","author":"Liu","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.colsurfb.2026.116106_bib187","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2025.102665","article-title":"Quercetin-functionalized nanomaterials: Innovative therapeutic avenues for Alzheimer's disease management","volume":"104","author":"Pei","year":"2025","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.colsurfb.2026.116106_bib188","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2024.113907","article-title":"Quercetin-derived red emission carbon dots: A multifunctional theranostic nano-agent against Alzheimer\u2019s \u03b2-amyloid fibrillogenesis","volume":"238","author":"Wei","year":"2024","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib189","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.162676","article-title":"Near-infrared threonine-quercetin carbon dots for bioimaging and dual protection against liver and brain injury via oral and intravenous administration","volume":"512","author":"Liu","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2026.116106_bib190","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtemb.2025.127591","article-title":"Deciphering the role of hepcidin in iron metabolism and anemia management","volume":"87","author":"Kesharwani","year":"2025","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib191","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12902-023-01280-y","article-title":"The effect of different types of anemia on HbA1c levels in non-diabetics","volume":"23","author":"Alzahrani","year":"2023","journal-title":"BMC Endocr. Disord."},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116106_bib192","first-page":"598","article-title":"Anemia of inflammation and iron metabolism in chronic diseases","volume":"224","author":"D\u00edez","year":"2024","journal-title":"Rev. Cl. \u00ednica Espa\u00f1ola"},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116106_bib193","doi-asserted-by":"crossref","first-page":"9723","DOI":"10.1021\/acs.jmedchem.5c00546","article-title":"A Novel Compound 3a-M1, from Metabolites of Sinomenine Derivative 3a, Exerts Potent Anti-Aplastic Anemia Activity via IP3R\/ORAI-Mediated CTL Ferroptosis","volume":"68","author":"Zhang","year":"2025","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.colsurfb.2026.116106_bib194","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.147848","article-title":"A highly branched arabinogalactan from Codonopsis pilosula: Structural insights and hematopoietic-protective mechanism","volume":"330","author":"Zhu","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib195","doi-asserted-by":"crossref","first-page":"4562","DOI":"10.1021\/acsami.4c17885","article-title":"Therapeutic potential of carbon dots derived from phytochemicals as nanozymes exhibiting superoxide dismutase activity for anemia","volume":"17","author":"Lu","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib196","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.freeradbiomed.2025.04.022","article-title":"Cuproptosis, a potential target for the therapy of diabetic critical limb ischemia","volume":"234","author":"Bai","year":"2025","journal-title":"Free. Radic. Biol. Med."},{"key":"10.1016\/j.colsurfb.2026.116106_bib197","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2019.103691","article-title":"Salidroside alleviates lipotoxicity-induced cell death through inhibition of TLR4\/MAPKs pathway, and independently of AMPK and autophagy in AML-12 mouse hepatocytes","volume":"65","author":"Dou","year":"2020","journal-title":"J. Funct. Foods"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib198","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1021\/acs.jmedchem.1c00947","article-title":"Discovery of salidroside-derivated glycoside analogues as novel angiogenesis agents to treat diabetic hind limb ischemia","volume":"65","author":"Liu","year":"2021","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.colsurfb.2026.116106_bib199","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.157265","article-title":"Conductive hydrogel with responsive release of Herbal-Derived carbon dots for neurovascular reconstruction in diabetic critical limb ischemia","volume":"500","author":"Zhou","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib200","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanmic.2024.100992","article-title":"Addressing urgent priorities in antibiotic development: insights from WHO 2023 antibacterial clinical pipeline analyses","volume":"6","author":"Melchiorri","year":"2025","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.colsurfb.2026.116106_bib201","article-title":"Natural biomass-derived carbon dots as potent antimicrobial agents against multidrug-resistant bacteria and their biofilms","volume":"36","author":"Wang","year":"2023","journal-title":"Sustain. Mater. Technol."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116106_bib202","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/smm2.1131","article-title":"Recent advances of carbon dots as new antimicrobial agents","volume":"3","author":"Li","year":"2022","journal-title":"SmartMat"},{"key":"10.1016\/j.colsurfb.2026.116106_bib203","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2025.120999","article-title":"Single-step synthesized carbon quantum dots from Centella asiatica hairy roots: Photoluminescent, biocompatibility, antibacterial and anticancer activity","volume":"229","author":"Taheri","year":"2025","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.colsurfb.2026.116106_bib204","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2025.172210","article-title":"Carbon dots with concurrent antibacterial, anti-inflammatory, and osteogenic activities for visualized therapy of infected bone defects through modulating bone immune microenvironment","volume":"527","author":"Xia","year":"2026","journal-title":"Chem. Eng. J."},{"issue":"Pt 4","key":"10.1016\/j.colsurfb.2026.116106_bib205","article-title":"Natural fluorescent carbon quantum dots embedded polyvinyl alcohol\/chitosan film with photoregulation and high antibacterial efficiency for infected wound healing","volume":"306","author":"Wen","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"40","key":"10.1016\/j.colsurfb.2026.116106_bib206","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202406681","article-title":"Intelligent Carbon Dots with Switchable Photo-Activated Oxidase-Mimicking Activity and pH Responsive Antioxidant Activity Adaptive to the Wound Microenvironment for Selective Antibacterial Therapy","volume":"11","author":"He","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2026.116106_bib207","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.130477","article-title":"Antimicrobial carbon dots\/pectin-based hydrogel for promoting healing processes in multidrug-resistant bacteria-infected wounds","volume":"264","author":"Sheng","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib208","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1007\/s12274-021-3818-9","article-title":"Near-infrared carbon nanodots for effective identification and inactivation of Gram-positive bacteria","volume":"15","author":"Zhao","year":"2022","journal-title":"Nano Res."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib209","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1186\/s12951-025-03509-5","article-title":"Zinc-doped curcumin carbon dots promote infected wound healing with photodynamic via the VEGF signaling pathway","volume":"23","author":"Zhao","year":"2025","journal-title":"J. Nanobiotechnol."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib210","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/s41392-024-02071-0","article-title":"Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases","volume":"10","author":"Chen","year":"2025","journal-title":"Signal. Transduct. Target. Ther."},{"key":"10.1016\/j.colsurfb.2026.116106_bib211","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jare.2025.01.002","article-title":"Mechanism and regulation of iron absorption throughout the life cycle","volume":"77","author":"Qiu","year":"2025","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.colsurfb.2026.116106_bib212","doi-asserted-by":"crossref","DOI":"10.1016\/j.inoche.2022.110034","article-title":"Green synthesis of mustard seeds carbon dots and study on fluorescence quenching mechanism of Fe3+ ions","volume":"146","author":"Zhang","year":"2022","journal-title":"Inorg. Chem. Commun."},{"issue":"8","key":"10.1016\/j.colsurfb.2026.116106_bib213","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1080\/15548627.2023.2200554","article-title":"Copper metabolism in cell death and autophagy","volume":"19","author":"Xue","year":"2023","journal-title":"Autophagy"},{"issue":"18","key":"10.1016\/j.colsurfb.2026.116106_bib214","doi-asserted-by":"crossref","first-page":"8877","DOI":"10.1039\/D3NJ00359K","article-title":"One-step green synthesis of carbon dots derived from Plumeria alba flowers for sensing and bioimaging","volume":"47","author":"He","year":"2023","journal-title":"New. J. Chem."},{"key":"10.1016\/j.colsurfb.2026.116106_bib215","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2022.107375","article-title":"Magnolia denudata leaf-derived near-infrared carbon dots as fluorescent nanoprobes for palladium (\u2161) detection and cell imaging","volume":"178","author":"Qu","year":"2022","journal-title":"Microchem. J."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib216","doi-asserted-by":"crossref","first-page":"4356","DOI":"10.1016\/j.ceramint.2022.09.321","article-title":"Enzyme-based fluorometric biosensor-based on coffee waste-derived carbon dots modified with APBA and NADP+ cofactor for selective dual detection of \u03b3-aminobutyric acid in in vitro and in vivo models","volume":"49","author":"Sangubotla","year":"2023","journal-title":"Ceram. Int."},{"key":"10.1016\/j.colsurfb.2026.116106_bib217","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121703","article-title":"Sophora japonica L. flower mediated carbon dots with nitrogen and sulfur co-doped as a sensitive fluorescent probe for amoxicillin detection","volume":"282","author":"Guo","year":"2022","journal-title":"Spectrochim. Acta Part. A Mol. Biomol. Spectrosc."},{"issue":"24","key":"10.1016\/j.colsurfb.2026.116106_bib218","doi-asserted-by":"crossref","first-page":"8141","DOI":"10.3390\/molecules28248141","article-title":"Quercetin: A Potential Polydynamic Drug","volume":"28","author":"Georgiou","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.colsurfb.2026.116106_bib219","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113673","article-title":"N-doped carbon quantum dots from Osmanthus fragrans as a novel off-on fluorescent nanosensor for highly sensitive detection of quercetin and aluminium ion, and cell imaging","volume":"192","author":"Yu","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"8","key":"10.1016\/j.colsurfb.2026.116106_bib220","doi-asserted-by":"crossref","first-page":"276","DOI":"10.31083\/j.fbl2908276","article-title":"Interaction of exosomal MicroRNA and oxidative stress in the pathogenesis of Colitis-associated cancer","volume":"29","author":"Li","year":"2024","journal-title":"Front. Biosci. Landmark"},{"key":"10.1016\/j.colsurfb.2026.116106_bib221","article-title":"Tremella-derived carbon dots-based UV\u2013vis\/fluorescent dual-output sensing platform for multiplex miRNA detection","author":"He","year":"2025","journal-title":"Biosens. Bioelectron."},{"issue":"6","key":"10.1016\/j.colsurfb.2026.116106_bib222","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00604-024-06428-8","article-title":"A target-triggered strand displacement-assisted target recycling based on carbon dots-based fluorescent probe and MSNs@ PDA nanoparticles for miRNA amplified detection and fluorescence imaging","volume":"191","author":"Gao","year":"2024","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.colsurfb.2026.116106_bib223","article-title":"Allium sativum derived carbon dots as a potential theranostic agent to combat the COVID-19 crisis","volume":"2","author":"Kalkal","year":"2021","journal-title":"Sens. Int."},{"issue":"8","key":"10.1016\/j.colsurfb.2026.116106_bib224","doi-asserted-by":"crossref","first-page":"10441","DOI":"10.1021\/acsami.2c21319","article-title":"Glycyrrhizic acid-based carbonized dots boost antiviral activity against influenza A virus via multisite inhibition mechanisms","volume":"15","author":"Li","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.116106_bib225","article-title":"Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib226","doi-asserted-by":"crossref","first-page":"446","DOI":"10.3390\/molecules25030446","article-title":"Haemostatic nanoparticles-derived bioactivity of from Selaginella tamariscina Carbonisata","volume":"25","author":"Zhao","year":"2020","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib227","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2217\/nnm-2018-0285","article-title":"Hemostatic and hepatoprotective bioactivity of junci medulla carbonisata-derived carbon dots","volume":"14","author":"Cheng","year":"2019","journal-title":"Nanomedicine"},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116106_bib228","doi-asserted-by":"crossref","first-page":"391","DOI":"10.2217\/nnm-2017-0297","article-title":"Novel Phellodendri Cortex (Huang Bo)-derived carbon dots and their hemostatic effect","volume":"13","author":"Liu","year":"2018","journal-title":"Nanomedicine"},{"issue":"49","key":"10.1016\/j.colsurfb.2026.116106_bib229","article-title":"Carbonized Platycladus orientalis derived carbon dots accelerate hemostasis through activation of platelets and coagulation pathways","volume":"19","author":"Liang","year":"2023","journal-title":"Small"},{"issue":"19","key":"10.1016\/j.colsurfb.2026.116106_bib230","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202200905","article-title":"Carbon dots as a potential therapeutic agent for the treatment of cancer-related anemia","volume":"34","author":"Xu","year":"2022","journal-title":"Adv. Mater."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib231","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/s12951-021-00847-y","article-title":"Green Phellodendri Chinensis Cortex-based carbon dots for ameliorating imiquimod-induced psoriasis-like inflammation in mice","volume":"19","author":"Zhang","year":"2021","journal-title":"J. Nanobiotechnol."},{"issue":"13","key":"10.1016\/j.colsurfb.2026.116106_bib232","article-title":"Glycyrrhizic-acid-based carbon dots with high antiviral activity by multisite inhibition mechanisms","volume":"16","author":"Tong","year":"2020","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2026.116106_bib233","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2025.115592","article-title":"Enhancing organoid technology with carbon-based nanomaterial biosensors: Advancements, challenges, and future directions","volume":"222","author":"Rezaei","year":"2025","journal-title":"Adv. Drug. Deliv. Rev."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib234","doi-asserted-by":"crossref","first-page":"4843","DOI":"10.1038\/s41467-024-49172-6","article-title":"Machine learning-guided realization of full-color high-quantum-yield carbon quantum dots","volume":"15","author":"Guo","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.colsurfb.2026.116106_bib235","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116684","article-title":"Next-generation 3D tumor modeling: A microfluidic platform with biocompatible red carbon dots for live cell imaging in co-cultured elongated spheroid tumor model","volume":"266","author":"Pournemat","year":"2024","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116106_bib236","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-50397-5","article-title":"Synthesis and characterization of mono-disperse carbon quantum dots from fennel seeds: photoluminescence analysis using machine learning","volume":"9","author":"Dager","year":"2019","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116106_bib237","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1021\/acs.langmuir.4c03945","article-title":"Machine learning-assisted biomass-derived carbon dots as fluorescent sensor array for discrimination of warfarin and its metabolites","volume":"41","author":"Li","year":"2025","journal-title":"Langmuir"}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526006946?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526006946?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T19:48:26Z","timestamp":1788551306000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776526006946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":237,"alternative-id":["S0927776526006946"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.116106","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Medicinal plant-derived carbon dots: Preparation strategies, functional properties, and biomedical applications","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.116106","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116106"}}