{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:28:07Z","timestamp":1793924887508,"version":"4.8.0"},"reference-count":84,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006560","name":"Yildiz Technical University","doi-asserted-by":"publisher","award":["FDK-2025-7027"],"award-info":[{"award-number":["FDK-2025-7027"]}],"id":[{"id":"10.13039\/501100006560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.colsurfb.2026.116119","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T15:20:44Z","timestamp":1788016844000},"page":"116119","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Epidermal growth factor receptor-responsive supramolecular curcumin\/carboxymethyl \u03b2-cyclodextrin self-assemblies enable improved treatment of triple-negative breast cancer"],"prefix":"10.1016","volume":"269","author":[{"given":"Irem","family":"Coksu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pelin","family":"Pelit Arayici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma Sayan","family":"Poyraz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Banu","family":"Mansuroglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serap","family":"Acar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2026.116119_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2024.114220","article-title":"Metformin-loaded chitosan nanoparticles augment silver nanoparticle-induced radiosensitization in breast cancer cells during radiation therapy","volume":"245","author":"Shiridokht","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116119_bib2","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA a cancer journal clinicians"},{"issue":"11","key":"10.1016\/j.colsurfb.2026.116119_bib3","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.3390\/pharmaceutics16111408","article-title":"Optimizing antitumor effect of triple-negative breast cancer via rosmarinic acid\u2013\u03b2-cyclodextrin inclusion complex","volume":"16","author":"Li","year":"2024","journal-title":"Pharmaceutics"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib4","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/s13046-022-02476-1","article-title":"Heterogeneity of triple negative breast cancer: current advances in subtyping and treatment implications","volume":"41","author":"Asleh","year":"2022","journal-title":"J. Exp. & Clin. Cancer Res."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib5","doi-asserted-by":"crossref","first-page":"18150","DOI":"10.1038\/s41598-024-69009-y","article-title":"A comparative study of sericin and gluten for magnetic nanoparticle-mediated drug delivery to breast cancer cell lines","volume":"14","author":"Jalilian","year":"2024","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.colsurfb.2026.116119_bib6","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1007\/s11095-012-0700-1","article-title":"Inclusion complex of novel curcumin analogue CDF and \u03b2-cyclodextrin (1: 2) and its enhanced in vivo anticancer activity against pancreatic cancer","volume":"29","author":"Dandawate","year":"2012","journal-title":"Pharm. Res."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116119_bib7","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1021\/jf104402t","article-title":"Curcumin nanoparticles: preparation, characterization, and antimicrobial study","volume":"59","author":"Bhawana","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.colsurfb.2026.116119_bib8","series-title":"Cyclodextrins and Their Complexes: Chemistry, Analytical Methods, Applications","first-page":"381","article-title":"Pharmaceutical applications of cyclodextrins and their derivatives","author":"Uekama","year":"2006"},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116119_bib9","doi-asserted-by":"crossref","first-page":"166","DOI":"10.34172\/apb.2020.022","article-title":"Cyclodextrin based nanoparticles for drug delivery and theranostics","volume":"10","author":"Gadade","year":"2020","journal-title":"Adv. Pharm. Bull."},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116119_bib10","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.addr.2013.05.001","article-title":"Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective","volume":"65","author":"Zhang","year":"2013","journal-title":"Adv. Drug. Deliv. Rev."},{"issue":"22","key":"10.1016\/j.colsurfb.2026.116119_bib11","doi-asserted-by":"crossref","first-page":"5319","DOI":"10.3390\/molecules29225319","article-title":"Cyclodextrins: advances in chemistry, toxicology, and multifaceted applications","volume":"29","author":"Musuc","year":"2024","journal-title":"Molecules"},{"key":"10.1016\/j.colsurfb.2026.116119_bib12","doi-asserted-by":"crossref","first-page":"4275","DOI":"10.2147\/IJN.S410688","article-title":"Targeted drug delivery systems for curcumin in breast cancer therapy","author":"Huang","year":"2023","journal-title":"Int. J. Nanomed."},{"issue":"18","key":"10.1016\/j.colsurfb.2026.116119_bib13","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.2217\/nnm-2016-0194","article-title":"Targeted nanoparticles for colorectal cancer","volume":"11","author":"Cisterna","year":"2016","journal-title":"Nanomedicine"},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116119_bib14","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/j.ijpharm.2016.08.011","article-title":"Design of smart GE11-PLGA\/PEG-PLGA blend nanoparticulate platforms for parenteral administration of hydrophilic macromolecular drugs: synthesis, preparation and in vitro\/ex vivo characterization","volume":"511","author":"Colzani","year":"2016","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2026.116119_bib15","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejpb.2022.05.004","article-title":"Structure-based peptide ligand design for improved epidermal growth factor receptor targeted gene delivery","volume":"176","author":"Decker","year":"2022","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"14","key":"10.1016\/j.colsurfb.2026.116119_bib16","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1096\/fj.05-4058com","article-title":"Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics","volume":"19","author":"Li","year":"2005","journal-title":"FASEB J."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116119_bib17","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3390\/pharmaceutics10040196","article-title":"Modulation of hypoxia-induced chemoresistance to polymeric micellar cisplatin: the effect of ligand modification of micellar carrier versus inhibition of the mediators of drug resistance","volume":"10","author":"Soleymani Abyaneh","year":"2018","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.colsurfb.2026.116119_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.nano.2023.102669","article-title":"Peptide-functionalized therapeutic nanoplatform for treatment orthotopic triple negative breast cancer and bone metastasis","volume":"50","author":"Li","year":"2023","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"20","key":"10.1016\/j.colsurfb.2026.116119_bib19","doi-asserted-by":"crossref","first-page":"15461","DOI":"10.1021\/acs.jmedchem.1c01505","article-title":"Targeted delivery and site-specific activation of \u03b2-cyclodextrin-conjugated photosensitizers for photodynamic therapy through a supramolecular bio-orthogonal approach","volume":"64","author":"Xue","year":"2021","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.colsurfb.2026.116119_bib20","doi-asserted-by":"crossref","DOI":"10.1177\/15330338211004954","article-title":"GE11 modified PLGA\/TPGS nanoparticles targeting delivery of salinomycin to breast cancer cells","volume":"20","author":"Li","year":"2021","journal-title":"Technol. Cancer Res. & Treat."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib21","article-title":"GE11 peptide conjugated liposomes for EGFR-targeted and chemophotothermal combined anticancer therapy","volume":"2021","author":"Huang","year":"2021","journal-title":"Bioinorg. Chem. Appl."},{"key":"10.1016\/j.colsurfb.2026.116119_bib22","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.dyepig.2018.11.055","article-title":"Synthesis and biological evaluation of phthalocyanine-peptide conjugate for EGFR-targeted photodynamic therapy and bioimaging","volume":"163","author":"Yu","year":"2019","journal-title":"Dyes Pigments"},{"issue":"32","key":"10.1016\/j.colsurfb.2026.116119_bib23","doi-asserted-by":"crossref","first-page":"9483","DOI":"10.1002\/slct.201901375","article-title":"Rabies virus 31D peptide-[P (VP-co-AA)] conjugates: synthesis, characterization and cytotoxicity evaluation","volume":"4","author":"Arayici","year":"2019","journal-title":"ChemistrySelect"},{"key":"10.1016\/j.colsurfb.2026.116119_bib24","article-title":"Enhancing the treatment of Staphylococcus aureus infections: a nanosystem with including dual antimicrobial peptide","volume":"97","author":"Coksu","year":"2024","journal-title":"J. Drug. Deliv. Sci. Technol."},{"key":"10.1016\/j.colsurfb.2026.116119_bib25","article-title":"Targeted delivery of rifaximin using P6. 2-decorated bifunctional PLGA nanoparticles for combating Staphylococcus aureus infections","volume":"161","author":"Arayici","year":"2024","journal-title":"Biomater. Adv."},{"key":"10.1016\/j.colsurfb.2026.116119_bib26","author":"Higuchi","year":"1965","journal-title":"Phase-solubility Tech."},{"key":"10.1016\/j.colsurfb.2026.116119_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jddst.2025.107411","article-title":"Bioc-cyclodextrin with protocatechuic acid ethyl ester: increased solubility, stability and antioxidant activity","author":"Coksu","year":"2025","journal-title":"J. Drug. Deliv. Sci. Technol."},{"issue":"7","key":"10.1016\/j.colsurfb.2026.116119_bib28","article-title":"Enhanced antimicrobial potency and stability of juglone\/\u03b2-cyclodextrin inclusion complexes: a comparative study of formulation methods","volume":"11","author":"Aray\u0131c\u0131","year":"2024","journal-title":"Mater. Res. Express"},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116119_bib29","doi-asserted-by":"crossref","DOI":"10.1088\/2632-959X\/ad64f1","article-title":"Design, synthesis and anti-oxidant activities of novel 1, 2, 3, 4-tetrazine, 1, 2, 3-triazoles and coumarin derivatives and their nanoparticular encapsulation","volume":"5","author":"Eyilcim","year":"2024","journal-title":"Nano Express"},{"issue":"8","key":"10.1016\/j.colsurfb.2026.116119_bib30","doi-asserted-by":"crossref","first-page":"3589","DOI":"10.1111\/1750-3841.15835","article-title":"Fabrication and characterization of ethyl acetate\u2013hydroxypropyl-\u03b2-cyclodextrin inclusion complex","volume":"86","author":"Zhu","year":"2021","journal-title":"J. Food Sci."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib31","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.vibspec.2010.01.012","article-title":"Infrared spectroscopy and Raman spectroscopy of cyclodextrin derivatives and their ferrocene inclusion complexes","volume":"53","author":"Heise","year":"2010","journal-title":"Vib. Spectrosc."},{"issue":"14","key":"10.1016\/j.colsurfb.2026.116119_bib32","doi-asserted-by":"crossref","first-page":"4521","DOI":"10.3390\/molecules27144521","article-title":"Galangin\/\u03b2-cyclodextrin inclusion complex as a drug-delivery system for improved solubility and biocompatibility in breast cancer treatment","volume":"27","author":"Abbas","year":"2022","journal-title":"Molecules"},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116119_bib33","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s10965-019-1994-z","article-title":"Changes in chemical stability and bioactivities of curcumin by forming inclusion complexes of beta-and Gama-cyclodextrins","volume":"27","author":"Alizadeh","year":"2020","journal-title":"J. Polym. Res."},{"key":"10.1016\/j.colsurfb.2026.116119_bib34","first-page":"4309","article-title":"The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel\/dimethyl-\u03b2-cyclodextrin inclusion complexes","author":"Ye","year":"2015","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2026.116119_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2019.127159","article-title":"Characterization and stability of beta-acids\/hydroxypropyl-\u03b2-cyclodextrin inclusion complex","volume":"1201","author":"Gu","year":"2020","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.colsurfb.2026.116119_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2022.114149","article-title":"Preparation and characterization of curcumin\/\u03b2-cyclodextrin nanoparticles by nanoprecipitation to improve the stability and bioavailability of curcumin","volume":"171","author":"Jiang","year":"2022","journal-title":"Lwt"},{"key":"10.1016\/j.colsurfb.2026.116119_bib37","series-title":"ISO 10993-5: 2009 (E). Biological evaluation of medical devices\u2014Part 5: Tests for cytotoxicity in vitro","year":"2009"},{"issue":"39","key":"10.1016\/j.colsurfb.2026.116119_bib38","doi-asserted-by":"crossref","first-page":"40329","DOI":"10.1021\/acsomega.4c00216","article-title":"Sinapic-acid-loaded nanoparticles optimized via experimental design methods: cytotoxic, antiapoptotoic, antiproliferative, and antioxidant activity","volume":"9","author":"Poyraz","year":"2024","journal-title":"ACS Omega"},{"key":"10.1016\/j.colsurfb.2026.116119_bib39","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.procbio.2023.09.016","article-title":"Investigation of cellular and molecular mechanisms of caffeic acid phenethyl ester loaded nanoparticle systems in breast cancer cell lines","volume":"134","author":"Poyraz","year":"2023","journal-title":"Process. Biochem."},{"key":"10.1016\/j.colsurfb.2026.116119_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120415","article-title":"Fufang epimedium formula alleviates acute liver injury through dual modulation of PI3K\/AKT\/Bcl-2 anti-apoptotic signaling pathway and cGAS-STING-IRF3 anti-inflammatory signaling pathway","author":"Feng","year":"2025","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116119_bib41","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ijpharm.2015.10.049","article-title":"Endocytosis of fluorescent cyclodextrins by intestinal Caco-2 cells and its role in paclitaxel drug delivery","volume":"496","author":"R\u00e9ti-Nagy","year":"2015","journal-title":"Int. J. Pharm."},{"issue":"15","key":"10.1016\/j.colsurfb.2026.116119_bib42","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.3390\/polym16152161","article-title":"Folic-acid-conjugated poly (lactic-co-glycolic acid) nanoparticles loaded with gallic acid induce glioblastoma cell death by reactive-oxygen-species-induced stress","volume":"16","author":"Ramalho","year":"2024","journal-title":"Polymers"},{"issue":"14","key":"10.1016\/j.colsurfb.2026.116119_bib43","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1002\/jsfa.4425","article-title":"Phase solubility studies and stability of cholesterol\/\u03b2-cyclodextrin inclusion complexes","volume":"91","author":"dos Santos","year":"2011","journal-title":"J. Sci. Food Agric."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib44","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.colsurfb.2010.03.039","article-title":"\u03b2-Cyclodextrin-curcumin self-assembly enhances curcumin delivery in prostate cancer cells","volume":"79","author":"Yallapu","year":"2010","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116119_bib45","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1080\/21655979.2016.1197029","article-title":"Comparative analysis of protective effects of curcumin, curcumin-\u03b2-cyclodextrin nanoparticle and nanoliposomal curcumin on unsymmetrical dimethyl hydrazine poisoning in mice","volume":"7","author":"Li","year":"2016","journal-title":"Bioengineered"},{"key":"10.1016\/j.colsurfb.2026.116119_bib46","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.2147\/DDDT.S320119","article-title":"A novel folic acid receptor-targeted drug delivery system based on curcumin-loaded \u03b2-cyclodextrin nanoparticles for cancer treatment","author":"Hong","year":"2021","journal-title":"Drug. Des. Dev. Ther."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116119_bib47","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.progpolymsci.2005.09.004","article-title":"Polymer\u2013drug conjugates: progress in polymeric prodrugs","volume":"31","author":"Khandare","year":"2006","journal-title":"Progress. Polym. Sci."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib48","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1146\/annurev-chembioeng-092319-083243","article-title":"Molecular modeling and simulations of peptide\u2013polymer conjugates","volume":"11","author":"Taylor","year":"2020","journal-title":"Annu. Rev. Chem. Biomol. Eng."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib49","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1039\/D1RA05980G","article-title":"Conjugation with gold nanoparticles improves the stability of the KT2 peptide and maintains its anticancer properties","volume":"12","author":"Maraming","year":"2022","journal-title":"RSC Adv."},{"issue":"12","key":"10.1016\/j.colsurfb.2026.116119_bib50","first-page":"939","article-title":"Preparation, characterization and antiproliferative activity of thymoquinone-\u03b2-cyclodextrin self assembling nanoparticles","volume":"68","author":"Abu-Dahab","year":"2013","journal-title":"Die Pharm. - Int. J. Pharm. Sci."},{"issue":"23","key":"10.1016\/j.colsurfb.2026.116119_bib51","doi-asserted-by":"crossref","first-page":"4073","DOI":"10.3390\/polym13234073","article-title":"Evaluation and characterization of curcumin-\u03b2-cyclodextrin and cyclodextrin-based nanosponge inclusion complexation","volume":"13","author":"Mashaqbeh","year":"2021","journal-title":"Polymers"},{"key":"10.1016\/j.colsurfb.2026.116119_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2020.129774","article-title":"In-vitro studies of Curcumin-\u03b2-cyclodextrin inclusion complex as sustained release system","volume":"1228","author":"Arya","year":"2021","journal-title":"J. Mol. Struct."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116119_bib53","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1080\/21655979.2016.1197029","article-title":"Comparative analysis of protective effects of curcumin, curcumin-\u03b2-cyclodextrin nanoparticle and nanoliposomal curcumin on unsymmetrical dimethyl hydrazine poisoning in mice","volume":"7","author":"Li","year":"2016","journal-title":"Bioengineered"},{"key":"10.1016\/j.colsurfb.2026.116119_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.molliq.2023.122841","article-title":"Curcumin\/amphiphilic cyclodextrin nanoassemblies: Theoretical and spectroscopic studies to address their debut in anticancer therapy","volume":"389","author":"Zagami","year":"2023","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.colsurfb.2026.116119_bib55","doi-asserted-by":"crossref","first-page":"5125","DOI":"10.2147\/IJN.S113469","article-title":"GE11 peptide modified and reduction-responsive hyaluronic acid-based nanoparticles induced higher efficacy of doxorubicin for breast carcinoma therapy","author":"Hu","year":"2016","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2026.116119_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2021.118892","article-title":"Development of oral curcumin based on pH-responsive transmembrane peptide-cyclodextrin derivative nanoparticles for hepatoma","volume":"277","author":"Wei","year":"2022","journal-title":"Carbohydr. Polym."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib57","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s12951-014-0043-7","article-title":"Gefitinib loaded folate decorated bovine serum albumin conjugated carboxymethyl-beta-cyclodextrin nanoparticles enhance drug delivery and attenuate autophagy in folate receptor-positive cancer cells","volume":"12","author":"Shi","year":"2014","journal-title":"J. nanobiotechnology"},{"key":"10.1016\/j.colsurfb.2026.116119_bib58","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.foodchem.2013.12.067","article-title":"Curcumin\u2013\u03b2-cyclodextrin inclusion complex: Stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application","volume":"153","author":"Mangolim","year":"2014","journal-title":"Food Chem."},{"key":"10.1016\/j.colsurfb.2026.116119_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.126397","article-title":"Fast-dissolving antioxidant curcumin\/cyclodextrin inclusion complex electrospun nanofibrous webs","volume":"317","author":"Celebioglu","year":"2020","journal-title":"Food Chem."},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116119_bib60","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.3390\/molecules23051179","article-title":"Characterization of curcumin\/cyclodextrin polymer inclusion complex and investigation on its antioxidant and antiproliferative activities","volume":"23","author":"Chen","year":"2018","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.colsurfb.2026.116119_bib61","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1080\/01932691.2019.1611440","article-title":"Carboxymethylated-\u03b2-cyclodextrin\/chitosan particles: bulk solids and aqueous dispersions","volume":"41","author":"Stopilha","year":"2020","journal-title":"J. Dispers. Sci. Technol."},{"issue":"4","key":"10.1016\/j.colsurfb.2026.116119_bib62","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/j.carbpol.2012.07.057","article-title":"Investigation of inclusion complex of cilnidipine with hydroxypropyl-\u03b2-cyclodextrin","volume":"90","author":"Hu","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.colsurfb.2026.116119_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2023.135174","article-title":"Insight into the inclusion mechanisms of curcumin in \u03b2-cyclodextrin using a screening strategy: molecular simulation and experimental study","volume":"1281","author":"Song","year":"2023","journal-title":"J. Mol. Struct."},{"issue":"10","key":"10.1016\/j.colsurfb.2026.116119_bib64","doi-asserted-by":"crossref","first-page":"4871","DOI":"10.3390\/ijms26104871","article-title":"Bioimaging and sensing properties of curcumin and derivatives","volume":"26","author":"Gangemi","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.colsurfb.2026.116119_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.121287","article-title":"Keto-enol tautomerism of curcumin in the preparation of nanobiocomposites with fumed silica","volume":"277","author":"Kazakova","year":"2022","journal-title":"Spectrochim. Acta Part. A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.colsurfb.2026.116119_bib66","first-page":"2023","article-title":"Development and characterization of co-crystals assisted with in-silico screening for solubility and permeability enhancement of curcumin","author":"Singh","year":"2023","journal-title":"bioRxiv"},{"key":"10.1016\/j.colsurfb.2026.116119_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfa.2020.124602","article-title":"Curcumin degradation kinetics in micellar solutions: enhanced stability in the presence of cationic surfactants","volume":"592","author":"Aboudiab","year":"2020","journal-title":"Colloids Surf. A Physicochem. Eng. Asp."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116119_bib68","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1039\/C6FO01770C","article-title":"Potential roles of chemical degradation in the biological activities of curcumin","volume":"8","author":"Zhu","year":"2017","journal-title":"Food & Funct."},{"key":"10.1016\/j.colsurfb.2026.116119_bib69","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2023.115405","article-title":"Enhancing stability of curcumin-loaded casein nanoparticles by adding liposomal nanoparticles","volume":"189","author":"Liu","year":"2023","journal-title":"Lwt"},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116119_bib70","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3390\/pharmaceutics15020382","article-title":"The formulation of curcumin: 2-hydroxypropyl-\u03b2-cyclodextrin complex with smart hydrogel for prolonged release of curcumin","volume":"15","author":"Nikoli\u0107","year":"2023","journal-title":"Pharmaceutics"},{"issue":"11","key":"10.1016\/j.colsurfb.2026.116119_bib71","doi-asserted-by":"crossref","first-page":"922","DOI":"10.3390\/gels11110922","article-title":"\u03b2-cyclodextrin inclusion complexes of curcumin and synthetic analogues in PVA\/carrageenan hydrogels: a platform for sustained release and microbial control","volume":"11","author":"Zank","year":"2025","journal-title":"Gels"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib72","article-title":"Cytotoxicity evaluation of endodontic pins on L929 cell line","volume":"2019","author":"Cannella","year":"2019","journal-title":"BioMed. Res. Int."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib73","doi-asserted-by":"crossref","first-page":"7201","DOI":"10.1038\/s41598-017-07489-x","article-title":"Chemotherapy treatment induces an increase of autophagy in the luminal breast cancer cell MCF7, but not in the triple-negative MDA-MB231","volume":"7","author":"Garbar","year":"2017","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116119_bib74","first-page":"1266","article-title":"Curcumin inhibits proliferation and promotes apoptosis of breast cancer cells","volume":"16","author":"Hu","year":"2018","journal-title":"Exp. Ther. Med."},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116119_bib75","doi-asserted-by":"crossref","first-page":"679","DOI":"10.3390\/nu12030679","article-title":"Mechanism of anti-cancer activity of curcumin on androgen-dependent and androgen-independent prostate cancer","volume":"12","author":"Abd. Wahab","year":"2020","journal-title":"Nutrients"},{"issue":"14","key":"10.1016\/j.colsurfb.2026.116119_bib76","doi-asserted-by":"crossref","first-page":"3427","DOI":"10.3390\/cancers13143427","article-title":"Curcumin: modulator of key molecular signaling pathways in hormone-independent breast cancer","volume":"13","author":"Farghadani","year":"2021","journal-title":"Cancers"},{"issue":"3","key":"10.1016\/j.colsurfb.2026.116119_bib77","doi-asserted-by":"crossref","first-page":"e0319846","DOI":"10.1371\/journal.pone.0319846","article-title":"Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells","volume":"20","author":"Bao","year":"2025","journal-title":"PloS. One"},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116119_bib78","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.3390\/molecules26092776","article-title":"Insights into the behavior of triple-negative MDA-MB-231 breast carcinoma cells following the treatment with 17\u03b2-ethinylestradiol and levonorgestrel","volume":"26","author":"Simu","year":"2021","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.colsurfb.2026.116119_bib79","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.3892\/mmr.2012.1103","article-title":"Curcumin induces apoptosis of triple-negative breast cancer cells by inhibition of EGFR expression","volume":"6","author":"Sun","year":"2012","journal-title":"Mol. Med. Rep."},{"issue":"8","key":"10.1016\/j.colsurfb.2026.116119_bib80","doi-asserted-by":"crossref","first-page":"12537","DOI":"10.1002\/jcp.28122","article-title":"Mechanisms of apoptosis modulation by curcumin: implications for cancer therapy","volume":"234","author":"Mortezaee","year":"2019","journal-title":"J. Cell. Physiol."},{"issue":"7","key":"10.1016\/j.colsurfb.2026.116119_bib81","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/aob\/mcq243","article-title":"Proliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulation","volume":"107","author":"Strzalka","year":"2011","journal-title":"Ann. Bot."},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116119_bib82","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.3892\/mmr.2015.3450","article-title":"Curcumin triggers apoptosis via upregulation of Bax\/Bcl-2 ratio and caspase activation in SW872 human adipocytes","volume":"12","author":"Zhu","year":"2015","journal-title":"Mol. Med. Rep."},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116119_bib83","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s11051-015-3132-0","article-title":"Peptide-conjugated micelles as a targeting nanocarrier for gene delivery","volume":"17","author":"Lin","year":"2015","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.colsurfb.2026.116119_bib84","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.biopha.2015.01.027","article-title":"Design and biological activity of epidermal growth factor receptor-targeted peptide doxorubicin conjugate","volume":"70","author":"Fan","year":"2015","journal-title":"Biomed. & Pharmacother."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526007071?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776526007071?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:01:00Z","timestamp":1793923260000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776526007071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":84,"alternative-id":["S0927776526007071"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.116119","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidermal growth factor receptor-responsive supramolecular curcumin\/carboxymethyl \u03b2-cyclodextrin self-assemblies enable improved treatment of triple-negative breast cancer","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.116119","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116119"}}