{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T00:27:44Z","timestamp":1793924864541,"version":"4.8.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273981"],"award-info":[{"award-number":["82273981"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373838"],"award-info":[{"award-number":["82373838"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82504646"],"award-info":[{"award-number":["82504646"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.colsurfb.2026.116224","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T15:48:58Z","timestamp":1790783338000},"page":"116224","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Cinnamaldehyde-derived doped carbon dots induce multifaceted antibacterial activity for robust anti-infection without acquired resistance"],"prefix":"10.1016","volume":"269","author":[{"given":"Xin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cunshan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Limei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3494-8575","authenticated-orcid":false,"given":"Liqing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2026.116224_bib1","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.cell.2024.01.030","article-title":"Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis","volume":"187","author":"Qiu","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.colsurfb.2026.116224_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202310342","article-title":"Progress and challenges in tumor ferroptosis treatment strategies: a comprehensive review of metal complexes and nanomedicine","volume":"20","author":"Su","year":"2024","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2026.116224_bib3","doi-asserted-by":"crossref","DOI":"10.1002\/prp2.70213","article-title":"Paeonol inhibits cell growth by inducing ferroptosis in human glioma cells","volume":"14","author":"Li","year":"2026","journal-title":"Pharmacol. Res. Perspect."},{"key":"10.1016\/j.colsurfb.2026.116224_bib4","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s00204-025-04198-7","article-title":"piR-16404 drives ferroptotic liver injury via CASTOR1\/mTORC1\/GPX4 dysregulation in HepG2 cells and mice: a novel toxicity mechanism of N, N-dimethylformamide","volume":"100","author":"Ma","year":"2026","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.colsurfb.2026.116224_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2024.127728","article-title":"Induction of ferroptosis: a new strategy for the control of bacterial infections","volume":"284","author":"Guo","year":"2024","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.colsurfb.2026.116224_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2020.100981","article-title":"Nano-decocted ferrous polysulfide coordinates ferroptosis-like death in bacteria for anti-infection therapy","volume":"35","author":"Shen","year":"2020","journal-title":"Nano Today"},{"key":"10.1016\/j.colsurfb.2026.116224_bib7","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202305277","article-title":"Engineered bio-heterojunction confers extra- and intracellular bacterial ferroptosis and hunger-triggered cell protection for diabetic wound repair","volume":"36","author":"Dai","year":"2024","journal-title":"Adv. Mater."},{"key":"10.1016\/j.colsurfb.2026.116224_bib8","doi-asserted-by":"crossref","first-page":"11692","DOI":"10.1021\/acsnano.3c02365","article-title":"Hybrid biomimetic membrane coated particles-mediated bacterial ferroptosis for acute MRSA pneumonia","volume":"17","author":"Hu","year":"2023","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2026.116224_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202207961","article-title":"Photothermal nanozyme-based microneedle patch against refractory bacterial biofilm infection via iron-actuated janus ion therapy","volume":"34","author":"Zhu","year":"2022","journal-title":"Adv. Mater."},{"key":"10.1016\/j.colsurfb.2026.116224_bib10","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1021\/acsnano.2c10960","article-title":"Alkaline \u201cnanoswords\u201d coordinate ferroptosis-like bacterial death for antibiosis and osseointegration","volume":"17","author":"Xue","year":"2023","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.colsurfb.2026.116224_bib11","doi-asserted-by":"crossref","DOI":"10.1080\/10717544.2022.2152134","article-title":"Ferric-loaded lipid nanoparticles inducing ferroptosis-like cell death for antibacterial wound healing","volume":"30","author":"Zhou","year":"2023","journal-title":"Drug. Deliv."},{"key":"10.1016\/j.colsurfb.2026.116224_bib12","article-title":"Inhalable self-assembled celastrol for acute bacterial pneumonia treatment","volume":"18","author":"Li","year":"2025","journal-title":"Nano Res."},{"key":"10.1016\/j.colsurfb.2026.116224_bib13","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202112218","article-title":"Advances in the Sensing and Treatment of Wound Biofilms","volume":"61","author":"Darvishi","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.colsurfb.2026.116224_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2022.101602","article-title":"Biofilm microenvironment-responsive nanoparticles for the treatment of bacterial infection","volume":"46","author":"Hu","year":"2022","journal-title":"Nano Today"},{"key":"10.1016\/j.colsurfb.2026.116224_bib15","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1021\/acs.jmedchem.3c01652","article-title":"Endoplasmic Reticulum-Targeting Quinazolinone-Based Lipophilic Probe for Specific Photoinduced Ferroptosis and Its Induced Lipid Dynamic Regulation","volume":"67","author":"Xing","year":"2024","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.colsurfb.2026.116224_bib16","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/j.cell.2018.08.003","article-title":"SnapShot: Bacterial Quorum Sensing","volume":"174","author":"Eickhoff","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.colsurfb.2026.116224_bib17","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/nature24624","article-title":"Progress in and promise of bacterial quorum sensing research","volume":"551","author":"Whiteley","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.colsurfb.2026.116224_bib18","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.jiph.2023.04.014","article-title":"Efficacy and mortality of ceftazidime\/avibactam-based regimens in carbapenem-resistant Gram-negative bacteria infections: A retrospective multicenter observational study","volume":"16","author":"Zhuang","year":"2023","journal-title":"J. Infect. Public. Health"},{"key":"10.1016\/j.colsurfb.2026.116224_bib19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s15010-024-02324-8","article-title":"Ceftazidime\/avibactam versus polymyxin B in carbapenem-resistant Klebsiella pneumoniae infections: a propensity score-matched multicenter real-world study","volume":"53","author":"Zhuang","year":"2025","journal-title":"Infection"},{"key":"10.1016\/j.colsurfb.2026.116224_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.124464","article-title":"Derivatized chitosan-oil-in-water nanocapsules for trans-cinnamaldehyde delivery","volume":"240","author":"Berberolli","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.colsurfb.2026.116224_bib21","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.colsurfb.2018.05.054","article-title":"Chitosan encapsulation modulates the effect of trans-cinnamaldehyde on AHL-regulated quorum sensing activity","volume":"169","author":"Qin","year":"2018","journal-title":"Colloids Surf. B"},{"key":"10.1016\/j.colsurfb.2026.116224_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202300324","article-title":"Antibacterial Carbon Dots: Mechanisms, Design, and Applications","volume":"12","author":"Zhao","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.colsurfb.2026.116224_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2024.216211","article-title":"Antimicrobial carbon materials-based quantum dots: From synthesis strategies to antibacterial properties for diagnostic and therapeutic applications in wound healing","volume":"522","author":"Zare","year":"2025","journal-title":"Coord. Chem. Rev."},{"key":"10.1016\/j.colsurfb.2026.116224_bib24","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s42773-023-00282-2","article-title":"Current trends in antimicrobial activities of carbon nanostructures: potentiality and status of nanobiochar in comparison to carbon dots","volume":"6","author":"Nishshankage","year":"2024","journal-title":"Biochar"},{"key":"10.1016\/j.colsurfb.2026.116224_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2020.100879","article-title":"Hetero-atom-doped carbon dots: doping strategies, properties and applications","volume":"33","author":"Miao","year":"2020","journal-title":"Nano Today"},{"key":"10.1016\/j.colsurfb.2026.116224_bib26","first-page":"246","article-title":"Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing","volume":"12","author":"Liu","year":"2022","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.colsurfb.2026.116224_bib27","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1039\/D1MA01023A","article-title":"The characterisation of commercial 2D carbons: graphene, graphene oxide and reduced graphene oxide","volume":"3","author":"Albers","year":"2022","journal-title":"Mater. Adv."},{"key":"10.1016\/j.colsurfb.2026.116224_bib28","doi-asserted-by":"crossref","first-page":"16726","DOI":"10.1021\/acsnano.4c01780","article-title":"Carbon Dot-Loaded Apoptotic Vesicles Improve the Liver Kupffer Cell-Mediated Antibacterial Effect to Synergistically Alleviate Sepsis","volume":"18","author":"Xiang","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2026.116224_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodhyd.2023.109111","article-title":"Multifunctional cinnamaldehyde-tannic acid nano-emulsion\/chitosan composite film for mushroom preservation","volume":"145","author":"Fu","year":"2023","journal-title":"Food Hydrocoll."},{"key":"10.1016\/j.colsurfb.2026.116224_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2023.137337","article-title":"Metal-free nitrogen-doped carbon nanodots as an artificial nanozyme for enhanced antibacterial activity","volume":"411","author":"Wang","year":"2023","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.colsurfb.2026.116224_bib31","article-title":"Single-Atomic Iron Doped Carbon Dots with Both Photoluminescence and Oxidase-Like Activity","volume":"18","author":"Li","year":"2022","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2026.116224_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.145291","article-title":"Fe\/N-doped carbon dots-based nanozyme with super peroxidase activity, high biocompatibility and antibiofilm ability for food preservation","volume":"473","author":"Cui","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2026.116224_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbon.2024.119578","article-title":"Fabrication of N\/P-codoped carbon dots with anti-bacterial activity for enhanced aqueous lubrication performance","volume":"230","author":"Jin","year":"2024","journal-title":"Carbon"},{"key":"10.1016\/j.colsurfb.2026.116224_bib34","doi-asserted-by":"crossref","first-page":"18608","DOI":"10.1021\/acsami.2c21839","article-title":"Positively Charged Carbon Dots with Antibacterial and Antioxidant Dual Activities for Promoting Infected Wound Healing","volume":"15","author":"Qu","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2026.116224_bib35","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1016\/j.apsusc.2007.09.063","article-title":"Analysis of XPS spectra of Fe2+ and Fe3+ ions in oxide materials","volume":"254","author":"Yamashita","year":"2008","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.colsurfb.2026.116224_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.128996","article-title":"Engineering efficient artificial nanozyme based on chitosan grafted Fe-doped-carbon dots for bacteria biofilm eradication","volume":"435","author":"Pan","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.colsurfb.2026.116224_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132331","article-title":"Highly fluorescent N, F co-doped carbon dots with tunable light emission for multicolor bio-labeling and antibacterial applications","volume":"459","author":"Hua","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.colsurfb.2026.116224_bib38","doi-asserted-by":"crossref","first-page":"6703","DOI":"10.1021\/acsnano.7b01023","article-title":"Super-cationic carbon quantum dots synthesized from spermidine as an eye drop formulation for topical treatment of bacterial keratitis","volume":"11","author":"Jian","year":"2017","journal-title":"ACS Nano"},{"issue":"9","key":"10.1016\/j.colsurfb.2026.116224_bib39","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1021\/acschemneuro.5c00937","article-title":"pH-Dependent oxidase - and hydrolase-mimicking activity of nanoceria and its composite with nitrogen-doped carbon quantum dots for sensitive detection of dopamine, glutathione, and methyl paraoxon","volume":"17","author":"Chawre","year":"2026","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.colsurfb.2026.116224_bib40","article-title":"Natural compound rhein-based bimetallic nanosheets to induce ferroptosis and activate STING pathway for enhanced cancer immunotherapy","volume":"526","author":"Li","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2026.116224_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijid.2024.107109","article-title":"Comparative effectiveness and safety of six antibiotics in treating MRSA infections: a network meta-analysis","author":"Ju","year":"2024","journal-title":"Int. J. Infect. Dis. 146"},{"issue":"2","key":"10.1016\/j.colsurfb.2026.116224_bib42","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1128\/microbiolspec.GPP3-0039-2018","article-title":"Staphylococcus aureus secreted toxins and extracellular enzymes","volume":"7","author":"Tam","year":"2019","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.colsurfb.2026.116224_bib43","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1038\/s41556-024-01425-8","article-title":"Exploiting ferroptosis vulnerabilities in cancer","volume":"26","author":"Nakamura","year":"2024","journal-title":"Nat. Cell. Biol."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092777652600812X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092777652600812X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T23:57:19Z","timestamp":1793923039000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092777652600812X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":43,"alternative-id":["S092777652600812X"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.116224","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cinnamaldehyde-derived doped carbon dots induce multifaceted antibacterial activity for robust anti-infection without acquired resistance","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2026.116224","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116224"}}