{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T22:49:07Z","timestamp":1770677347105,"version":"3.49.0"},"reference-count":73,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers in Biology and Medicine"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.compbiomed.2012.08.009","type":"journal-article","created":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T19:33:17Z","timestamp":1349119997000},"page":"1079-1085","source":"Crossref","is-referenced-by-count":22,"title":["The possible role of HSPs on Beh\u00e7et's disease: A bioinformatic approach"],"prefix":"10.1016","volume":"42","author":[{"given":"Younes","family":"Ghasemi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Dabbagh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Rasoul-Amini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afshin","family":"Borhani Haghighi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Hossein","family":"Morowvat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.compbiomed.2012.08.009_bib1","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1136\/bjo.87.9.1175","article-title":"Behcet's Disease: from hippocrates to the third millennium","volume":"87","author":"Verity","year":"2003","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib2","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1136\/ard.60.11.996","article-title":"Behcet's disease: infectious aetiology, new autoantigens, and HLA-B51","volume":"60","author":"Direskeneli","year":"2001","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.survophthal.2005.04.009","article-title":"Current concepts in the etiology and treatment of Beh\u00e7et's disease","volume":"50","author":"Evereklioglu","year":"2005","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib4","first-page":"S27","article-title":"The role of infectious agents in the pathogenesis, clinical manifestations and treatment strategies in Beh\u00e7et's disease","volume":"25","author":"Mumcu","year":"2007","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib5","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.revmed.2006.02.014","article-title":"Pathophysiology of Beh\u00e7et's disease [Physiopathologie De La Maladie De Behcet]","volume":"27","author":"Amoura","year":"2006","journal-title":"Rev. Med. Interne"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1568-9972(03)00088-0","article-title":"Autoimmunity to heat shock proteins in atherosclerosis","volume":"3","author":"Mandal","year":"2004","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib7","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1038\/sj.jid.5700281","article-title":"HLA-Independent antibacterial host response toward Th1 immunity mediated by IL-12: a new concept for the pathogenesis of Adamantiades-Beh\u00e7et's disease","volume":"126","author":"Zouboulis","year":"2006","journal-title":"J. Invest. Dermatol."},{"issue":"Suppl. 30","key":"10.1016\/j.compbiomed.2012.08.009_bib8","first-page":"S44","article-title":"The role of heat shock proteins in Beh\u00e7et's disease","volume":"4","author":"Direskeneli","year":"2003","journal-title":"Clin. Exp. Rheumatol."},{"issue":"Suppl III","key":"10.1016\/j.compbiomed.2012.08.009_bib9","doi-asserted-by":"crossref","first-page":"iii65","DOI":"10.1136\/ard.2006.058495","article-title":"Heat shock proteins induce T cell regulation of chronic inflammation","volume":"65","author":"Hauet-Broere","year":"2006","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib10","series-title":"Heat Shock Proteins: Potent Mediators of Inflammation and Immunity","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4020-5585-0_3","article-title":"Mechanisms of stress-induced cellular HSP72 release","author":"Lancaster","year":"2007"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib11","series-title":"Heat Shock Proteins: Potent Mediators of Inflammation and Immunity","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4020-5585-0_8","article-title":"Interaction of heat shock protein 60 with innate immune cells","author":"Habich","year":"2007"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0009-8981(03)00340-1","article-title":"Diagnostic significance of antibodies to heat shock proteins","volume":"337","author":"Kim","year":"2003","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib13","series-title":"Heat Shock Proteins: Potent Mediators of Inflammation and Immunity","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4020-5585-0_6","article-title":"Heat shock proteins and scavenger receptors","author":"Delneste","year":"2007"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib14","series-title":"Heat Shock Proteins: Potent Mediators of Inflammation and Immunity","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4020-5585-0_4","article-title":"Roles of Extracellular heat shock proteins: a new sense of danger","author":"Williams","year":"2007"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib15","series-title":"Heat Shock Proteins: Potent Mediators of Inflammation and Immunity","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4020-5585-0_2","article-title":"HSP70 peptide acting as a danger signal for Natural Killer (NK) cells","author":"Multhoff","year":"2007"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib16","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.2165\/00003495-200767140-00004","article-title":"Standard and novel therapeutic approaches to Beh\u00e7et's disease","volume":"67","author":"G\u00fcl","year":"2007","journal-title":"Drugs"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib17","first-page":"506","article-title":"Skin hypersensitivity to streptococcal antigens and the induction of systemic symptoms by the antigens in Behcet's disease \u2013 a multicenter study","volume":"16","author":"Mizushima","year":"1989","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib18","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1042\/bst0310681","article-title":"The chaperonins: perspectives from the Archaea","volume":"31","author":"Lund","year":"2003","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib19","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0165-2478(01)00280-2","article-title":"Human HSP 60 peptide responsive T cell lines are similarly present in Both Beh\u00e7et's disease patients and healthy controls","volume":"79","author":"Saruhan-Direskeneli","year":"2001","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib20","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1365-2133.2006.07536.x","article-title":"The role of heat shock protein 60, vascular endothelial growth factor and antiphospholipid antibodies in Beh\u00e7et's disease","volume":"156","author":"Shaker","year":"2007","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib21","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00296-007-0470-y","article-title":"Differential expression of toll-like receptor 6 on granulocytes and monocytes implicates the role of microorganisms in Beh\u00e7et disease etiopathogenesis","volume":"28","author":"Yavuz","year":"2008","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib22","doi-asserted-by":"crossref","first-page":"R16","DOI":"10.1186\/ar2367","article-title":"Association of reduced heme oxygenase-1 with excessive toll-like receptor 4 expression in peripheral blood mononuclear cells in Beh\u00e7et's disease","volume":"10","author":"Kirino","year":"2008","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib23","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1365-2249.2005.02695.x","article-title":"Involvement of Th1 cells and heat shock protein 60 in the pathogenesis of intestinal Beh\u00e7et's disease","volume":"139","author":"Imamura","year":"2005","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib24","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1136\/ard.2007.079871","article-title":"Association of the toll-like receptor 4 gene polymorphisms with Beh\u00e7et's disease","volume":"67","author":"Meguro","year":"2008","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib25","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jaut.2009.09.007","article-title":"Self Heat-Shock protein 65-mediated regulation of autoimmune arthritis","volume":"33","author":"Durai","year":"2009","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib26","series-title":"Heat Shock Proteins: Potent Mediators of Inflammation and Immunity","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4020-5585-0_18","article-title":"Heat shock proteins are targets for T cell regulation: how microbial Hsp induce IL10 producing anti-inflammatory T cells","author":"Van Eden","year":"2007"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib27","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1111\/j.1365-3083.1994.tb03516.x","article-title":"The expression of carbohydrate antigens in activated T cells and in autoimmune diseases","volume":"40","author":"Fortune","year":"1994","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib28","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3349\/ymj.1997.38.6.350","article-title":"Etiopathology of Behcet's disease: immunological aspects","volume":"38","author":"Sakane","year":"1997","journal-title":"Yonsei Med. J."},{"issue":"12","key":"10.1016\/j.compbiomed.2012.08.009_bib29","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1093\/rheumatology\/kel329","article-title":"Autoimmunity vs autoinflammation in Beh\u00e7et's disease: do we oversimplify a complex disorder?","volume":"45","author":"Direskeneli","year":"2006","journal-title":"Rheumatology"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib30","first-page":"708","article-title":"Responses to 60\/65kDa heat shock protein derived peptides in turkish patients with Beh\u00e7et's disease","volume":"27","author":"Direskeneli","year":"2000","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib31","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1601-0825.2005.01144.x","article-title":"Mucosal diseases series: number VII Beh\u00e7et's disease (Adamantiades syndrome)","volume":"12","author":"Escudier","year":"2006","journal-title":"Oral Dis."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib32","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/S0140-6736(96)91121-6","article-title":"Role of \u03b3\u03b4 T cells in Beh\u00e7et's disease","volume":"347","author":"Gaston","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib33","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1365-2249.1997.3611265.x","article-title":"Characterization of T cells specific for an epitope of human 60-kD heat shock protein (HSP) in patients with Beh\u00e7et's disease (BD) in Japan","volume":"108","author":"Kaneko","year":"1997","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib34","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1128\/IAI.59.4.1434-1441.1991","article-title":"Association between the 65-Kilodalton heat shock protein, Streptococcus Sanguinis, and the corresponding antibodies in Beh\u00e7et's syndrome","volume":"59","author":"Lehner","year":"1991","journal-title":"Infect. Immun."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib35","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.4049\/jimmunol.151.4.2273","article-title":"Expression of mycobacterial and homologous human 65-kilodalton heat shock protein peptides in short term cell lines from patients with Beh\u00e7et's disease","volume":"151","author":"Pervin","year":"1993","journal-title":"J. Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib36","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1006\/exer.1998.0574","article-title":"HSP-derived peptides inducing uveitis and IgG and IgA antibodies","volume":"67","author":"Uchio","year":"1998","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1076\/ocii.7.2.69.4018","article-title":"Beh\u00e7et's disease and antibody titers to various heat-shock protein 60s","volume":"7","author":"Tanaka","year":"1999","journal-title":"Ocul. Immunol. Inflamm."},{"issue":"5","key":"10.1016\/j.compbiomed.2012.08.009_bib38","first-page":"489","article-title":"The role of streptococcal hypersensitivity in the pathogenesis of Beh\u00e7et's disease","volume":"18","author":"Kaneko","year":"2008","journal-title":"Eur. J. Dermatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib39","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF02931965","article-title":"The role of an uncommon type of oral Streptococcus sanguis in the etiology of Beh\u00e7et's disease","volume":"2","author":"Tsuchida","year":"1997","journal-title":"Environ. Health Prev. Med."},{"issue":"38","key":"10.1016\/j.compbiomed.2012.08.009_bib40","first-page":"S67","article-title":"Anti-Saccharomyces cerevisiae antibodies (ASCA) in Beh\u00e7et's syndrome","volume":"23","author":"Fresko","year":"2005","journal-title":"Clin. Exp. Rheumatol."},{"issue":"Suppl. 26","key":"10.1016\/j.compbiomed.2012.08.009_bib41","first-page":"S21","article-title":"Anti-Saccharomyces cerevisiae antibodies \u2013 a novel serologic marker for Beh\u00e7et's disease","volume":"20","author":"Krause","year":"2002","journal-title":"Clin. Exp. Rheumatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib42","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000018221","article-title":"Helicobacter pylori and Beh\u00e7et's disease","volume":"199","author":"Avc","year":"1999","journal-title":"Dermatology"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib43","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1080\/00365540410020730","article-title":"Evidence of chronic Chlamydia pneumoniae infection in patients with Beh\u00e7et's disease","volume":"36","author":"Ayaslioglu","year":"2004","journal-title":"Scand. J. Infect. Dis."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib44","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1111\/j.1468-3083.2009.03105.x","article-title":"Adamantiades Beh\u00e7et disease triggered by a tick bite and or Borrelia infection","volume":"23","author":"di Meo","year":"2009","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib45","doi-asserted-by":"crossref","first-page":"476","DOI":"10.3129\/i08-089","article-title":"Conjunctival flora in Beh\u00e7et patients","volume":"43","author":"G\u00fcnd\u00fcz","year":"2008","journal-title":"Can. J. Ophthalmol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib46","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1136\/ard.2003.017467","article-title":"The pustular skin lesions in Beh\u00e7et's syndrome are not sterile","volume":"63","author":"Hatemi","year":"2004","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s10067-005-1135-4","article-title":"A case of tuberculous meningoencephalitis in a patient with Beh\u00e7et's disease","volume":"25","author":"Iliopoulos","year":"2005","journal-title":"Clin. Rheumatol."},{"issue":"1","key":"10.1016\/j.compbiomed.2012.08.009_bib48","first-page":"64","article-title":"Role of Streptococcus sanguis and traumatic factors in Beh\u00e7et's disease","volume":"3","author":"Isogai","year":"2003","journal-title":"J. Appl. Res. Clin. Exp. Ther."},{"issue":"1","key":"10.1016\/j.compbiomed.2012.08.009_bib49","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0002-9394(14)76207-5","article-title":"Detection of antibodies against Borrelia burgdorferi in patients with uveitis","volume":"112","author":"Isogai","year":"1991","journal-title":"Am. J. Ophthalmol."},{"issue":"4","key":"10.1016\/j.compbiomed.2012.08.009_bib50","first-page":"385","article-title":"Beh\u00e7et's disease and streptococcal infection","volume":"30","author":"Namba","year":"1986","journal-title":"Jpn. J. Ophthalmol."},{"issue":"8","key":"10.1016\/j.compbiomed.2012.08.009_bib51","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0003-9969(95)00042-N","article-title":"Streptococcus oralis previously identified as uncommon \u2018Streptococcus sanguis\u2019 in Beh\u00e7et's disease","volume":"40","author":"Narikawa","year":"1995","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib52","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1007\/s10067-008-0844-x","article-title":"Clinical manifestations associated with high titer of anti-streptolysin O in Beh\u00e7et's disease","volume":"27","author":"Oh","year":"2008","journal-title":"Clin. Rheumatol."},{"issue":"2","key":"10.1016\/j.compbiomed.2012.08.009_bib53","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1365-2133.1995.tb02640.x","article-title":"A case of Beh\u00e7et's disease aggravated by gingival infection with methicillin-resistant Staphylococcus aureus","volume":"133","author":"Suga","year":"1995","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib54","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1038\/sj.jid.5700203","article-title":"Role of IL-12B promoter polymorphism in Adamantiades-Beh\u00e7et's disease susceptibility: an involvement of Th1 immunoreactivity against Streptococcus sanguinis antigen","volume":"126","author":"Yanagihori","year":"2006","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib55","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/s00296-008-0709-2","article-title":"The anti-Helicobacter pylori Antibiotherapy for the treatment of recurrent oral aphthous ulcers in a patient with Beh\u00e7et's syndrome","volume":"29","author":"Yildirim","year":"2009","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib56","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/molbev\/msm092","article-title":"MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0","volume":"24","author":"Tamura","year":"2007","journal-title":"Mol. Biol. Evol."},{"issue":"1","key":"10.1016\/j.compbiomed.2012.08.009_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2958.1995.tb02216.x","article-title":"Evolution of the chaperonin families (Hsp60, Hsp10 and Tcp-1) of proteins and the origin of eukaryotic cells","volume":"15","author":"Gupta","year":"1995","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib58","first-page":"406","article-title":"The neighbor-joining method: a new method for reconstructing phylogenetic trees","volume":"4","author":"Saitou","year":"1987","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib59","doi-asserted-by":"crossref","first-page":"783","DOI":"10.2307\/2408678","article-title":"Confidence limits on phylogenies: an approach using the bootstrap","volume":"39","author":"Felsenstein","year":"1985","journal-title":"Evolution"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib60","doi-asserted-by":"crossref","first-page":"11030","DOI":"10.1073\/pnas.0404206101","article-title":"Prospects for inferring very large phylogenies by using the neighbor-joining method","volume":"101","author":"Tamura","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib61","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s12038-007-0008-1","article-title":"Comparison of sequence-based and structure-based phylogenetic trees of homologous proteins: inferences on protein evolution","volume":"32","author":"Balaji","year":"2007","journal-title":"J. Biosci."},{"issue":"1","key":"10.1016\/j.compbiomed.2012.08.009_bib62","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3109\/08830189709116842","article-title":"The role of heat shock protein, microbial and autoimmune agents in the aetiology of Beh\u00e7et's disease","volume":"14","author":"Lehner","year":"1997","journal-title":"Int. Rev. Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib63","first-page":"359","article-title":"Infection, autoimmunity and autoimmune disease","volume":"77","author":"Feige","year":"1996","journal-title":"EXS"},{"issue":"7","key":"10.1016\/j.compbiomed.2012.08.009_bib64","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1007\/BF02118311","article-title":"Heat shock proteins in autoimmune disease. from causative antigen to specific therapy?","volume":"48","author":"Yang","year":"1992","journal-title":"Experientia"},{"issue":"6","key":"10.1016\/j.compbiomed.2012.08.009_bib65","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/S0952-7915(05)80016-0","article-title":"Autoimmunity associated with infection: leprosy, acute rheumatic fever and lyme disease","volume":"3","author":"Ehrenstein","year":"1991","journal-title":"Curr. Opin. Immunol."},{"issue":"8","key":"10.1016\/j.compbiomed.2012.08.009_bib66","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.it.2009.05.005","article-title":"Infections and autoimmunity \u2013 friends or foes?","volume":"30","author":"Kivity","year":"2009","journal-title":"Trends Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib67","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00430-002-0167-5","article-title":"Pathogenesis of Adamantiades-Beh\u00e7et's disease","volume":"192","author":"Zouboulis","year":"2003","journal-title":"Med. Microbiol. Immunol."},{"issue":"Suppl. 24","key":"10.1016\/j.compbiomed.2012.08.009_bib68","first-page":"S6","article-title":"Beh\u00e7et's disease: an update on the pathogenesis","volume":"19","author":"G\u00fcl","year":"2001","journal-title":"Clin. Exp. Rheumatol."},{"issue":"3","key":"10.1016\/j.compbiomed.2012.08.009_bib69","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0167-5699(93)90210-C","article-title":"Sequence homologies between Hsp60 and autoantigens","volume":"14","author":"Jones","year":"1993","journal-title":"Immunol. Today"},{"key":"10.1016\/j.compbiomed.2012.08.009_bib70","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1365-2249.2004.02688.x","article-title":"Excessive expression of Txk, a member of the Tec family of tyrosine kinases, contributes to excessive Th1 cytokine production by T lymphocytes in patients with Beh\u00e7et's disease","volume":"139","author":"Nagafuchi","year":"2005","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib71","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1468-3083.2003.t01-1-00574.x","article-title":"Nitric oxide levels in Beh\u00e7et's disease","volume":"17","author":"Sancak","year":"2003","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib72","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1399-302X.2005.00207.x","article-title":"Detection of heat shock proteins but not superantigen by isolated oral bacteria from patients with Beh\u00e7et's disease","volume":"20","author":"Miura","year":"2005","journal-title":"Oral Microbiol. Immunol."},{"key":"10.1016\/j.compbiomed.2012.08.009_bib73","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.biocel.2008.09.012","article-title":"Evolutionarily conserved antigens in autoimmune disease: implications for an infective aetiology","volume":"41","author":"Wegner","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."}],"container-title":["Computers in Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010482512001370?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010482512001370?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T21:19:09Z","timestamp":1744233549000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0010482512001370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":73,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0010482512001370"],"URL":"https:\/\/doi.org\/10.1016\/j.compbiomed.2012.08.009","relation":{},"ISSN":["0010-4825"],"issn-type":[{"value":"0010-4825","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}