{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T13:27:27Z","timestamp":1774531647466,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["patient-research.elsevier.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comprehensive Psychiatry"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.comppsych.2014.02.001","type":"journal-article","created":{"date-parts":[[2014,2,12]],"date-time":"2014-02-12T13:00:45Z","timestamp":1392210045000},"page":"1069-1076","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Differential impact of anxiety symptoms and anxiety disorders on treatment outcome for psychotic depression in the STOP-PD study"],"prefix":"10.1016","volume":"55","author":[{"given":"Simon J.C.","family":"Davies","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benoit H.","family":"Mulsant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alastair J.","family":"Flint","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony J.","family":"Rothschild","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen M.","family":"Whyte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barnett S.","family":"Meyers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.comppsych.2014.02.001_bb0005","first-page":"50","article-title":"Fluoxetine, placebo, and tricyclic antidepressants in major depression with and without anxious features","volume":"55","author":"Tollefson","year":"1994","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0010","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/da.10045","article-title":"Achieving remission with venlafaxine and fluoxetine in major depression: its relationship to anxiety symptoms","volume":"16","author":"Davidson","year":"2002","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0015","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1192\/bjp.bp.106.027169","article-title":"Effect of comorbid anxiety on treatment response and relapse risk in late-life depression: controlled study","volume":"190","author":"Andreescu","year":"2007","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0020","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1176\/appi.ajp.2008.07081340","article-title":"Empirically derived decision trees for the treatment of late-life depression","volume":"165","author":"Andreescu","year":"2008","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0025","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1176\/appi.ajp.2007.06111868","article-title":"Difference in treatment outcome in outpatients with anxious versus nonanxious depression: a STAR*D report","volume":"165","author":"Fava","year":"2008","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0030","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.psychres.2008.02.011","article-title":"Psychic and somatic anxiety symptoms as predictors of response to fluoxetine in major depressive disorder","volume":"161","author":"Papakostas","year":"2008","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0035","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1002\/da.20544","article-title":"High worry severity is associated with poorer acute and maintenance efficacy of antidepressants in late-life depression","volume":"26","author":"Andreescu","year":"2009","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0040","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1176\/appi.ajp.2007.07121927","article-title":"Anxious Depression and Response to Treatment","volume":"165","author":"Nelson","year":"2008","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0045","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.4088\/JCP.v69n0812","article-title":"Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of major depressive disorder with high levels of anxiety (anxious depression): a pooled analysis of 10 studies","volume":"69","author":"Papakostas","year":"2008","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0050","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/gps.2233","article-title":"Anxiety does not predict response to antidepressant treatment in late life depression: results of a meta-analysis","volume":"24","author":"Nelson","year":"2009","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0055","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.euroneuro.2011.09.009","article-title":"Severe and anxious depression: Combining definitions of clinical sub-types to identify patients differentially responsive to selective serotonin reuptake inhibitors","volume":"22","author":"Papakostas","year":"2012","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0060","doi-asserted-by":"crossref","first-page":"486","DOI":"10.4088\/JCP.11r07324","article-title":"Are antipsychotics or antidepressants needed for psychotic depression? A systematic review and meta-analysis of trials comparing antidepressant or antipsychotic monotherapy with combination treatment","volume":"73","author":"Farahani","year":"2012","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0065","doi-asserted-by":"crossref","first-page":"839","DOI":"10.4088\/JCP.10r06218blu","article-title":"The pharmacologic treatment of anxiety disorders: a review of progress","volume":"71","author":"Ravindran","year":"2010","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0070","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1001\/archgenpsychiatry.2009.79","article-title":"A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD)","volume":"66","author":"Meyers","year":"2009","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0075","first-page":"799","article-title":"The Brief Psychiatric Rating Scale","volume":"10","author":"Overall","year":"1962","journal-title":"Psychological Research"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0080","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/schbul\/19.4.709","article-title":"Schizophrenia in late-life: elderly patients admitted to an acute care psychiatric hospital","volume":"19","author":"Mulsant","year":"1993","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0085","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1097\/YIC.0b013e3282f948f5","article-title":"The GRID-HAM-D standardization of the Hamilton Depression Rating Scale","volume":"23","author":"Williams","year":"2008","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0090","series-title":"Stata Statistical Software: Release 12","author":"StataCorp","year":"2011"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0095","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1176\/ajp.138.3.328","article-title":"Delusional and nondelusional unipolar depression: further evidence for distinct subtypes","volume":"138","author":"Charney","year":"1981","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0100","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0920-9964(01)00373-5","article-title":"Panic attacks in schizophrenia","volume":"58","author":"Goodwin","year":"2002","journal-title":"Schizophr Res"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0105","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0005-7967(02)00095-5","article-title":"A comparison of metacognitions in patients with hallucinations, delusions, panic disorder, and non-patient controls","volume":"41","author":"Morrison","year":"2003","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0110","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1017\/S1092852900019714","article-title":"Anxiety and schizophrenia: the interaction of subtypes of anxiety and psychotic symptoms","volume":"10","author":"Huppert","year":"2005","journal-title":"CNS Spectr"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0115","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1001\/archpsyc.56.10.921","article-title":"The structure of common mental disorders","volume":"56","author":"Krueger","year":"1999","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0120","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1001\/archpsyc.58.6.597","article-title":"The structure and stability of common mental disorders: The NEMESIS Study","volume":"58","author":"Vollebergh","year":"2001","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0125","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1001\/archpsyc.60.9.929","article-title":"The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women","volume":"60","author":"Kendler","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.comppsych.2014.02.001_bb0130","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/00019442-200501000-00011","article-title":"Generalized anxiety disorder in late life: lifetime course and comorbidity with major depressive disorder","volume":"13","author":"Lenze","year":"2005","journal-title":"Am J Geriatr Psychiatry"}],"container-title":["Comprehensive Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010440X14000212?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010440X14000212?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,6]],"date-time":"2018-10-06T18:26:46Z","timestamp":1538850406000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0010440X14000212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["S0010440X14000212"],"URL":"https:\/\/doi.org\/10.1016\/j.comppsych.2014.02.001","relation":{},"ISSN":["0010-440X"],"issn-type":[{"value":"0010-440X","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential impact of anxiety symptoms and anxiety disorders on treatment outcome for psychotic depression in the STOP-PD study","name":"articletitle","label":"Article Title"},{"value":"Comprehensive Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.comppsych.2014.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}