{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:58:25Z","timestamp":1790722705731,"version":"4.1.0"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T00:00:00Z","timestamp":1645747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bmn.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Neurobiology"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.conb.2022.102526","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T14:03:22Z","timestamp":1648217002000},"page":"102526","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Neural mechanisms of persistent aggression"],"prefix":"10.1016","volume":"73","author":[{"given":"Eartha Mae","family":"Guthman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9756-7887","authenticated-orcid":false,"given":"Annegret L.","family":"Falkner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.conb.2022.102526_bib1","series-title":"The dynamics of aggression: biological and social processes in dyads and groups","author":"Potegal","year":"2013"},{"key":"10.1016\/j.conb.2022.102526_bib2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1093\/jhered\/esz023","article-title":"The heritability of behavior: a meta-analysis","volume":"110","author":"Dochtermann","year":"2019","journal-title":"J\u00a0Hered"},{"key":"10.1016\/j.conb.2022.102526_bib3","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/0163-1047(92)90339-6","article-title":"Time course of aggressive arousal in female hamsters and male rats","volume":"58","author":"Potegal","year":"1992","journal-title":"Behav Neural Biol"},{"key":"10.1016\/j.conb.2022.102526_bib4","first-page":"876","volume":"vol. 2","author":"Hinde","year":"1970"},{"key":"10.1016\/j.conb.2022.102526_bib5","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0003-3472(76)80054-1","article-title":"The interaction of stimulus patterns controlling aggressiveness in the cichild fish Haplochromis burtoni","volume":"24","author":"Heiligenberg","year":"1976","journal-title":"Anim Behav"},{"key":"10.1016\/j.conb.2022.102526_bib6","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/nn.4264","article-title":"Hypothalamic control of male aggression-seeking behavior","volume":"19","author":"Falkner","year":"2016","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.conb.2022.102526_bib7","doi-asserted-by":"crossref","first-page":"521","DOI":"10.2307\/1422147","article-title":"The foundations of ethology","volume":"95","author":"Hess","year":"1982","journal-title":"Am J Psychol"},{"key":"10.1016\/j.conb.2022.102526_bib8","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1037\/0735-7036.98.1.66","article-title":"Behavior of attack-primed and attack-satiated female golden hamsters (Mesocricetus auratus)","volume":"98","author":"Potegal","year":"1984","journal-title":"J\u00a0Comp Psychol"},{"key":"10.1016\/j.conb.2022.102526_bib9","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1439-0310.1970.tb01861.x","article-title":"The effect of a visual stimulus on the agonistic behaviour of the golden hamster","volume":"27","author":"Grant","year":"2010","journal-title":"Z\u00a0Tierpsychol"},{"key":"10.1016\/j.conb.2022.102526_bib10","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1163\/156853963X00185","article-title":"A\u00a0comparison of the social postures of some common laboratory rodents","volume":"21","author":"Mackintosh","year":"1963","journal-title":"Behaviour"},{"key":"10.1016\/j.conb.2022.102526_bib11","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/7854_2014_313","article-title":"Hypothalamic attack: a wonderful artifact or a useful perspective on escalation and pathology in aggression? A viewpoint","volume":"17","author":"Kruk","year":"2014","journal-title":"Curr Top Behav Neurosci"},{"key":"10.1016\/j.conb.2022.102526_bib12","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1163\/156853979X00106","article-title":"The induction of aggressive behaviour by electrical stimulation in the hypothalamus of male rats","volume":"70","author":"Kruk","year":"1979","journal-title":"Behaviour"},{"key":"10.1016\/j.conb.2022.102526_bib13","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1002\/cne.22735","article-title":"The vertebrate mesolimbic reward system and social behavior network: a comparative synthesis","volume":"519","author":"O'Connell","year":"2011","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.conb.2022.102526_bib14","doi-asserted-by":"crossref","DOI":"10.1038\/s41593-020-00715-2","article-title":"Neural mechanisms of aggression across species","author":"Lischinsky","year":"2020","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.conb.2022.102526_sref15","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1016\/j.neuron.2021.02.012","article-title":"Neural circuits of social behaviors: innate yet flexible","volume":"109","author":"Wei","year":"2021","journal-title":"Neuron"},{"key":"10.1016\/j.conb.2022.102526_sref16","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.neuron.2021.03.002","article-title":"A\u00a0substantia innominata-midbrain circuit controls a general aggressive response","volume":"109","author":"Zhu","year":"2021","journal-title":"Neuron"},{"key":"10.1016\/j.conb.2022.102526_sref17","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.neuron.2020.08.025","article-title":"Specific hypothalamic neurons required for sensing conspecific male cues relevant to inter-male aggression","volume":"108","author":"Chen","year":"2020","journal-title":"Neuron"},{"key":"10.1016\/j.conb.2022.102526_bib18","doi-asserted-by":"crossref","first-page":"5971","DOI":"10.1523\/JNEUROSCI.5109-13.2014","article-title":"Decoding ventromedial hypothalamic neural activity during male mouse aggression","volume":"34","author":"Falkner","year":"2014","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.conb.2022.102526_bib19","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.02743","article-title":"Sex-specific processing of social cues in the medial amygdala","volume":"3","author":"Bergan","year":"2014","journal-title":"Elife"},{"key":"10.1016\/j.conb.2022.102526_sref20","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2020.02.014","article-title":"Hierarchical representations of aggression in a hypothalamic-midbrain circuit","author":"Falkner","year":"2020","journal-title":"Neuron"},{"key":"10.1016\/j.conb.2022.102526_bib21","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/s41586-020-2995-0","article-title":"Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice","volume":"589","author":"Karigo","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.conb.2022.102526_bib22","doi-asserted-by":"crossref","DOI":"10.1126\/science.aau5324","article-title":"Molecular, spatial and functional single-cell profiling of the hypothalamic preoptic region","author":"Moffitt","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.conb.2022.102526_bib23","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.cell.2019.09.020","article-title":"Multimodal analysis of cell types in a hypothalamic node controlling social behavior","volume":"179","author":"Kim","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.conb.2022.102526_bib24","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.neuron.2010.03.024","article-title":"The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviors","volume":"66","author":"Juntti","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.conb.2022.102526_bib25","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1002\/cne.902940107","article-title":"Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study","volume":"294","author":"Simerly","year":"1990","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.conb.2022.102526_bib26","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0021-9258(18)77008-7","article-title":"The testicular hormone","volume":"84","author":"Gallagher","year":"1929","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.conb.2022.102526_bib27","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1001\/jama.1923.02650100027012","article-title":"AN ovarian hormone: preliminary report ON its localization, extraction and partial purification, and action IN test animals","volume":"81","author":"Allen","year":"1923","journal-title":"JAMA"},{"key":"10.1016\/j.conb.2022.102526_bib28","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1002\/hlca.193401701166","article-title":"Zur kenntnis der Corpus luteum-hormone (2. Mitteilung.)","volume":"17","author":"Hartmann","year":"1934","journal-title":"Helv Chim Acta"},{"key":"10.1016\/j.conb.2022.102526_bib29","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1002\/cber.19340670729","article-title":"Reindarstellung der Hormone aus dem Corpus luteum. (Vorl\u00e4uf. Mitteil.)","volume":"67","author":"Slotta","year":"1934","journal-title":"Ber Dtsch Chem Ges A\/B"},{"key":"10.1016\/j.conb.2022.102526_bib30","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1126\/science.80.2069.190.b","article-title":"Crystalline progestin","volume":"80","author":"Allen","year":"1934","journal-title":"Science"},{"key":"10.1016\/j.conb.2022.102526_bib31","first-page":"91","article-title":"Mating behavior in male rats castrated at various ages and injected with androgen","volume":"101","author":"Beach","year":"1946","journal-title":"J\u00a0Exp Zool"},{"key":"10.1016\/j.conb.2022.102526_bib32","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1086\/physzool.18.4.30151901","article-title":"Bisexual mating behavior in the male rat: effects of castration and hormone administration","volume":"18","author":"Beach","year":"1945","journal-title":"Physiol Zool"},{"key":"10.1016\/j.conb.2022.102526_bib33","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1210\/endo-65-3-369","article-title":"Organizing action of prenatally administered testosterone propionate on the tissues mediating mating behavior in the female Guinea pig","volume":"65","author":"Phoenix","year":"1959","journal-title":"Endocrinology"},{"key":"10.1016\/j.conb.2022.102526_bib34","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1126\/science.144.3615.185","article-title":"Estrogen administered neonatally affects adult sexual behavior IN male and female rats","volume":"144","author":"Levine","year":"1964","journal-title":"Science"},{"key":"10.1016\/j.conb.2022.102526_bib35","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1159\/000122866","article-title":"Activation of feminine sexual behavior in castrated male rats by intrahypothalamic implants of estradiol benzoate","volume":"28","author":"Davis","year":"1979","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.conb.2022.102526_bib36","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/0018-506X(85)90042-X","article-title":"Organizational and activational effects of sex steroids on brain and behavior: a reanalysis","volume":"19","author":"Arnold","year":"1985","journal-title":"Horm Behav"},{"key":"10.1016\/j.conb.2022.102526_bib37","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/nrendo.2011.122","article-title":"The G-protein-coupled estrogen receptor GPER in health and disease","volume":"7","author":"Prossnitz","year":"2011","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.conb.2022.102526_bib38","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.steroids.2018.01.010","article-title":"Membrane-initiated estrogen signaling via Gq-coupled GPCR in the central nervous system","volume":"142","author":"Vail","year":"2019","journal-title":"Steroids"},{"key":"10.1016\/j.conb.2022.102526_bib39","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1210\/en.2018-00987","article-title":"Membrane androgen receptors unrelated to nuclear steroid receptors","volume":"160","author":"Thomas","year":"2019","journal-title":"Endocrinology"},{"key":"10.1016\/j.conb.2022.102526_bib40","doi-asserted-by":"crossref","first-page":"8391","DOI":"10.1523\/JNEUROSCI.22-19-08391.2002","article-title":"ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury","volume":"22","author":"Toran-Allerand","year":"2002","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.conb.2022.102526_bib41","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/nrn1703","article-title":"Neurosteroids: endogenous regulators of the GABA(A) receptor","volume":"6","author":"Belelli","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.conb.2022.102526_bib42","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.cell.2011.12.018","article-title":"Modular genetic control of sexually dimorphic behaviors","volume":"148","author":"Xu","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.conb.2022.102526_sref43","first-page":"349290","article-title":"Regulation of neural gene expression by estrogen receptor alpha","volume":"10","author":"Gegenhuber","year":"2020","journal-title":"bioRxiv"},{"key":"10.1016\/j.conb.2022.102526_sref44","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/s41586-021-04010-3","article-title":"Oestrogen engages brain MC4R signaling to drive physical activity in female mice","volume":"599","author":"Krause","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.conb.2022.102526_bib45","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0006-8993(88)90789-5","article-title":"Estrogen-concentrating hypothalamic and limbic neurons project to the medial preoptic nucleus","volume":"451","author":"Akesson","year":"1988","journal-title":"Brain Res"},{"key":"10.1016\/j.conb.2022.102526_bib46","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1210\/en.2002-221069","article-title":"Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha","volume":"144","author":"Mitra","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.conb.2022.102526_bib47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/cne.901510204","article-title":"Atlas of estradiol-concentrating cells in the central nervous system of the female rat","volume":"151","author":"Pfaff","year":"1973","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.conb.2022.102526_bib48","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1159\/000127039","article-title":"Androgen and estrogen receptors coexist within individual neurons in the brain of the Syrian hamster","volume":"62","author":"Wood","year":"1995","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.conb.2022.102526_bib49","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.cell.2018.12.041","article-title":"Limbic neurons shape sex recognition and social behavior in sexually naive males","volume":"176","author":"Bayless","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.conb.2022.102526_bib50","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/nature13169","article-title":"Scalable control of mounting and attack by Esr1+ neurons in the ventromedial hypothalamus","volume":"509","author":"Lee","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.conb.2022.102526_bib51","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/nature23885","article-title":"Social behaviour shapes hypothalamic neural ensemble representations of conspecific sex","volume":"550","author":"Remedios","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.conb.2022.102526_bib52","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1038\/nn.4644","article-title":"Esr1+ cells in the ventromedial hypothalamus control female aggression","volume":"20","author":"Hashikawa","year":"2017","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.conb.2022.102526_bib53","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.neuron.2018.02.019","article-title":"A\u00a0hypothalamic midbrain pathway essential for driving maternal behaviors","volume":"98","author":"Fang","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.conb.2022.102526_sref54","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/j.cell.2019.10.025","article-title":"Periodic remodeling in a neural circuit governs timing of female sexual behavior","volume":"179","author":"Inoue","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.conb.2022.102526_bib55","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0149-7634(05)80179-4","article-title":"Hormone-dependent aggression in male and female rats: experiential, hormonal, and neural foundations","volume":"16","author":"Albert","year":"1992","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.conb.2022.102526_bib56","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.tig.2018.07.001","article-title":"The neural mechanisms of sexually dimorphic aggressive behaviors","volume":"34","author":"Hashikawa","year":"2018","journal-title":"Trends Genet"},{"key":"10.1016\/j.conb.2022.102526_bib57","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.cell.2021.02.028","article-title":"The neural circuitry of social homeostasis: consequences of acute versus chronic social isolation","volume":"184","author":"Lee","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.conb.2022.102526_sref58","doi-asserted-by":"crossref","first-page":"25789","DOI":"10.1073\/pnas.2011782117","article-title":"Experience-dependent plasticity in an innate social behavior is mediated by hypothalamic LTP","volume":"117","author":"Stagkourakis","year":"2020","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.conb.2022.102526_bib59","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0031-9384(90)90336-3","article-title":"Hormone-dependent aggression in male rats is proportional to serum testosterone concentration but sexual behavior is not","volume":"48","author":"Albert","year":"1990","journal-title":"Physiol Behav"},{"key":"10.1016\/j.conb.2022.102526_bib60","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0301-0082(80)90024-6","article-title":"The organization of intraspecific agonistic behaviour in the rat","volume":"15","author":"Koolhaas","year":"1980","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.conb.2022.102526_bib61","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0091-3057(82)90010-7","article-title":"Aggression induced by stimulation of the hypothalamus: effects of androgens","volume":"16","author":"Bermond","year":"1982","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.conb.2022.102526_bib62","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0306-4530(91)90069-6","article-title":"Synaptogenic action of sex steroids in developing and adult neuroendocrine brain","volume":"16","author":"Matsumoto","year":"1991","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.conb.2022.102526_bib63","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1159\/000124445","article-title":"Male-female difference in synaptic organization of the ventromedial nucleus of the hypothalamus in the rat","volume":"42","author":"Matsumoto","year":"1986","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.conb.2022.102526_bib64","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.yhbeh.2014.01.008","article-title":"Testosterone regulates the density of dendritic spines in the male preoptic area","volume":"65","author":"Garelick","year":"2014","journal-title":"Horm Behav"},{"key":"10.1016\/j.conb.2022.102526_bib65","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0006-8993(82)90218-9","article-title":"Ultrastructural changes in the hypothalamic ventromedial nucleus of ovariectomized rats after estrogen treatment","volume":"240","author":"Carrer","year":"1982","journal-title":"Brain Res"},{"key":"10.1016\/j.conb.2022.102526_bib66","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/cne.1106","article-title":"Influence of sex and estrus cycle on the sexual dimorphisms of the hypothalamic ventromedial nucleus: stereological evaluation and Golgi study","volume":"432","author":"Madeira","year":"2001","journal-title":"J\u00a0Comp Neurol"},{"key":"10.1016\/j.conb.2022.102526_bib67","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1007\/BF00247306","article-title":"Estrogen-induced alterations in synaptic morphology in the midbrain central gray","volume":"69","author":"Chung","year":"1988","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.conb.2022.102526_bib68","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0006-8993(87)91574-5","article-title":"Synaptic plasticity to estrogen in the lateral septum of the adult male and female rats","volume":"436","author":"Miyakawa","year":"1987","journal-title":"Brain Res"},{"key":"10.1016\/j.conb.2022.102526_bib69","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nn.4487","article-title":"Hormonal gain control of a medial preoptic area social reward circuit","volume":"20","author":"McHenry","year":"2017","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.conb.2022.102526_bib70","doi-asserted-by":"crossref","first-page":"7503","DOI":"10.1073\/pnas.1817503116","article-title":"Connectional architecture of a mouse hypothalamic circuit node controlling social behavior","volume":"116","author":"Lo","year":"2019","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.conb.2022.102526_bib71","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/nature09736","article-title":"Functional identification of an aggression locus in the mouse hypothalamus","volume":"470","author":"Lin","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.conb.2022.102526_bib72","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1038\/s41586-018-0244-6","article-title":"A\u00a0synaptic threshold mechanism for computing escape decisions","volume":"558","author":"Evans","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.conb.2022.102526_bib73","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.neuron.2019.05.025","article-title":"A\u00a0specialized neural circuit gates social vocalizations in the mouse","volume":"103","author":"Tschida","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.conb.2022.102526_bib74","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nmeth.3770","article-title":"Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain","volume":"13","author":"Kim","year":"2016","journal-title":"Nat Methods"},{"key":"10.1016\/j.conb.2022.102526_sref75","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/s41592-019-0400-4","article-title":"High-density multi-fiber photometry for studying large-scale brain circuit dynamics","volume":"16","author":"Sych","year":"2019","journal-title":"Nat Methods"},{"key":"10.1016\/j.conb.2022.102526_bib76","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.conb.2020.11.003","article-title":"Rethinking brain-wide interactions through multi-region \u2018network of networks\u2019 models","volume":"65","author":"Perich","year":"2020","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.conb.2022.102526_bib77","first-page":"423348","article-title":"Inferring brain-wide interactions using data-constrained recurrent neural network models","volume":"12","author":"Perich","year":"2020","journal-title":"bioRxiv"},{"key":"10.1016\/j.conb.2022.102526_bib78","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1038\/s41593-019-0533-x","article-title":"Unsupervised identification of the internal states that shape natural behavior","volume":"22","author":"Calhoun","year":"2019","journal-title":"Nat Neurosci"}],"container-title":["Current Opinion in Neurobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959438822000204?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959438822000204?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T13:02:12Z","timestamp":1760706132000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959438822000204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":78,"alternative-id":["S0959438822000204"],"URL":"https:\/\/doi.org\/10.1016\/j.conb.2022.102526","relation":{},"ISSN":["0959-4388"],"issn-type":[{"value":"0959-4388","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neural mechanisms of persistent aggression","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Neurobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.conb.2022.102526","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102526"}}