{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T11:10:22Z","timestamp":1767006622807,"version":"build-2065373602"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005892","name":"China Academy of Traditional Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005892","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contemporary Clinical Trials Communications"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.conctc.2022.100928","type":"journal-article","created":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T22:08:51Z","timestamp":1653689331000},"page":"100928","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["The clinical efficiency of transcriptome-based endometrial receptivity assessment (Tb-ERA) in Chinese patients with recurrent implantation failure (RIF): A study protocol for a prospective randomized controlled trial"],"prefix":"10.1016","volume":"28","author":[{"given":"Wen-bi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiu-cheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3972-698X","authenticated-orcid":false,"given":"Han","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-xi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.conctc.2022.100928_bib1","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.fertnstert.2012.03.010","article-title":"Repeated implantation failure: clinical approach","volume":"97","author":"Simon","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib2","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.rbmo.2013.08.011","article-title":"Recurrent implantation failure: definition and management","volume":"28","author":"Coughlan","year":"2014","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.conctc.2022.100928_bib3","first-page":"653","article-title":"Recurrent implantation failure: a comprehensive review","volume":"68","author":"Zohni","year":"2016","journal-title":"Minerva Ginecol."},{"key":"10.1016\/j.conctc.2022.100928_bib4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1055\/s-0034-1375182","article-title":"Remedies for recurrent implantation failure","volume":"32","author":"Zeyneloglu","year":"2014","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.conctc.2022.100928_bib5","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.fertnstert.2012.03.017","article-title":"Recurrent IVF failure: other factors","volume":"97","author":"Penzias","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib6","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.fertnstert.2013.04.035","article-title":"Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery rates: a randomized controlled trial","volume":"100","author":"Scott","year":"2013","journal-title":"Fertil. Steril."},{"issue":"12","key":"10.1016\/j.conctc.2022.100928_bib7","doi-asserted-by":"crossref","first-page":"2802","DOI":"10.1093\/humrep\/deu277","article-title":"Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles","volume":"29","author":"Fiorentino","year":"2014","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.conctc.2022.100928_bib8","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S1472-6483(10)61715-4","article-title":"Impact of preimplantation genetic diagnosis on IVF outcome in implantation failure patients","volume":"6","author":"Pehlivan","year":"2003","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.conctc.2022.100928_bib9","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.rbmo.2015.09.002","article-title":"Validation of next-generation sequencing for comprehensive chromosome screening of embryos","volume":"31","author":"Kung","year":"2015","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.conctc.2022.100928_bib10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0015-0282(16)30062-0","article-title":"Dating the endometrial biopsy","volume":"1","author":"Noyes","year":"1950","journal-title":"Fertil. Steril."},{"issue":"Suppl 1","key":"10.1016\/j.conctc.2022.100928_bib11","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1600-0897.2011.01048.x","article-title":"Endometrial receptivity and human embryo implantation","volume":"66","author":"Rashid","year":"2011","journal-title":"Am. J. Reprod. Immunol."},{"issue":"5","key":"10.1016\/j.conctc.2022.100928_bib12","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.fertnstert.2012.03.039","article-title":"Defective endometrial receptivity","volume":"97","author":"Revel","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib13","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.rbmo.2011.09.009","article-title":"Insights into human endometrial receptivity from transcriptomic and proteomic data","volume":"24","author":"Haouzi","year":"2012","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.conctc.2022.100928_bib14","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1093\/humrep\/dey023","article-title":"Asynchronous and pathological windows of implantation: two causes of recurrent implantation failure","volume":"33","author":"Sebastian-Leon","year":"2018","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.conctc.2022.100928_bib15","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.bpobgyn.2018.07.004","article-title":"What to do when good-quality embryos repeatedly fail to implant","volume":"53","author":"Coughlan","year":"2018","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"key":"10.1016\/j.conctc.2022.100928_bib16","doi-asserted-by":"crossref","first-page":"10077","DOI":"10.1038\/s41598-017-10098-3","article-title":"Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers","volume":"7","author":"Altmae","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.conctc.2022.100928_bib17","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.fertnstert.2012.12.005","article-title":"Profiling the gene signature of endometrial receptivity: cinical results","volume":"99","author":"Garrido-G\u00f3mez","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib18","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.fertnstert.2019.02.011","article-title":"Clinical approach to recurrent implantation failure: evidence-based evaluation of the endometrium","volume":"111","author":"Kliman","year":"2019","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib19","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0950-3552(05)80092-6","article-title":"The implantation window","volume":"6","author":"Harper","year":"1992","journal-title":"Baillieres Clin Obstet Gynaecol"},{"key":"10.1016\/j.conctc.2022.100928_bib20","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1056\/NEJM199906103402304","article-title":"Time of implantation of the conceptus and loss of pregnancy","volume":"340","author":"Wilcox","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.conctc.2022.100928_bib21","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.fertnstert.2010.04.063","article-title":"A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature","volume":"95","author":"Diaz-Gimeno","year":"2011","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib22","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.fertnstert.2012.09.046","article-title":"The accuracy and reproducibility of the endometrial receptivity array is superior to histology as a diagnostic method for endometrial receptivity","volume":"99","author":"Diaz-Gimeno","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib23","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/humrep\/deu070","article-title":"What a difference two days make: \u201cpersonalized\u201d embryo transfer (pET) paradigm: a case report and pilot study","volume":"29","author":"Ruiz-Alonso","year":"2014","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.conctc.2022.100928_bib24","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4103\/0974-1208.165153","article-title":"Endometrial receptivity array: clinical application","volume":"8","author":"Mahajan","year":"2015","journal-title":"J. Hum. Reprod. Sci."},{"issue":"3","key":"10.1016\/j.conctc.2022.100928_bib25","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.rbmo.2020.06.002","article-title":"A 5-year multicentre randomized controlled trial comparing personalized, frozen and fresh blastocyst transfer in IVF","volume":"41","author":"Sim\u00f3n","year":"2020","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.conctc.2022.100928_bib26","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.fertnstert.2013.05.004","article-title":"The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure","volume":"100","author":"Ruiz-Alonso","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.conctc.2022.100928_bib27","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/rmb2.12041","article-title":"Efficacy of the endometrial receptivity array for repeated implantation failure in Japan: a retrospective, two-centers study","volume":"16","author":"Hashimoto","year":"2017","journal-title":"Reprod. Med. Biol."},{"issue":"1","key":"10.1016\/j.conctc.2022.100928_bib28","doi-asserted-by":"crossref","first-page":"59","DOI":"10.4103\/jhrs.JHRS_74_18","article-title":"Personalized embryo transfer helps in improving in vitro fertilization\/ICSI outcomes in patients with recurrent implantation failure","volume":"12","author":"Patel","year":"2019","journal-title":"J. Hum. Reprod. Sci."},{"issue":"4","key":"10.1016\/j.conctc.2022.100928_bib29","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s10815-017-1112-2","article-title":"The role of the endometrial receptivity array (ERA) in patients who have failed euploid embryo transfers","volume":"35","author":"Tan","year":"2018","journal-title":"J. Assist. Reprod. Genet."},{"issue":"1","key":"10.1016\/j.conctc.2022.100928_bib30","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1186\/s12967-021-02837-y","article-title":"The role of transcriptomic biomarkers of endometrial receptivity in personalized embryo transfer for patients with repeated implantation failure","volume":"19","author":"He","year":"2021","journal-title":"J. Transl. Med."},{"issue":"1","key":"10.1016\/j.conctc.2022.100928_bib31","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.fertnstert.2020.11.010","article-title":"Transcriptomic analysis of endometrial receptivity for a genomic diagnostics model of Chinese women","volume":"116","author":"Zhang","year":"2021","journal-title":"Fertil. Steril."},{"issue":"6","key":"10.1016\/j.conctc.2022.100928_bib32","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/humrep\/der037","article-title":"The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting","volume":"26","year":"2011","journal-title":"Hum. Reprod."},{"issue":"12","key":"10.1016\/j.conctc.2022.100928_bib33","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1007\/s10815-015-0595-y","article-title":"Diminished ovarian reserve, premature ovarian failure, poor ovarian responder- a plea for universal definitions","volume":"32","author":"Cohen","year":"2015","journal-title":"J. Assist. Reprod. Genet."},{"issue":"4","key":"10.1016\/j.conctc.2022.100928_bib34","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s12064-012-0162-3","article-title":"Measurement of mRNA abundance using RNA-seq data: RPKM measure is inconsistent among samples","volume":"131","author":"Wagner","year":"2012","journal-title":"Theor. Biosci."},{"issue":"9","key":"10.1016\/j.conctc.2022.100928_bib35","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1101\/gr.135350.111","article-title":"GENCODE: the reference human genome annotation for the ENCODE Project","volume":"22","author":"Harrow","year":"2012","journal-title":"Genome Res."},{"issue":"12","key":"10.1016\/j.conctc.2022.100928_bib36","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1007\/s10815-020-01948-7","article-title":"Evaluation of the endometrial receptivity assay and the preimplantation genetic test for aneuploidy in overcoming recurrent implantation failure","volume":"37","author":"Mauro","year":"2020","journal-title":"J. Assist. Reprod. Genet."},{"issue":"6","key":"10.1016\/j.conctc.2022.100928_bib37","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.rbmo.2020.08.015","article-title":"Assessing endometrial receptivity after recurrent implantation failure: a prospective controlled cohort study","volume":"41","author":"Malene","year":"2020","journal-title":"Reprod. Biomed. Online"}],"container-title":["Contemporary Clinical Trials Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S245186542200045X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S245186542200045X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:06:04Z","timestamp":1762520764000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S245186542200045X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":37,"alternative-id":["S245186542200045X"],"URL":"https:\/\/doi.org\/10.1016\/j.conctc.2022.100928","relation":{},"ISSN":["2451-8654"],"issn-type":[{"type":"print","value":"2451-8654"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The clinical efficiency of transcriptome-based endometrial receptivity assessment (Tb-ERA) in Chinese patients with recurrent implantation failure (RIF): A study protocol for a prospective randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Contemporary Clinical Trials Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.conctc.2022.100928","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100928"}}