{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:59:24Z","timestamp":1780631964984,"version":"3.54.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contraception"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.contraception.2005.07.010","type":"journal-article","created":{"date-parts":[[2005,9,27]],"date-time":"2005-09-27T14:19:16Z","timestamp":1127830756000},"page":"23-29","source":"Crossref","is-referenced-by-count":28,"title":["Treating acne with oral contraceptives: use of lower doses"],"prefix":"10.1016","volume":"73","author":[{"given":"Johannes","family":"Huber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Walch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.contraception.2005.07.010_bib1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1001\/archfami.9.2.179","article-title":"New treatments and therapeutic strategies for acne","volume":"9","author":"Thiboutot","year":"2000","journal-title":"Arch Fam Med"},{"key":"10.1016\/j.contraception.2005.07.010_bib2","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1210\/jcem-71-1-8","article-title":"Attenuation of mild hyperandrogenic activity in postpubertal acne by a triphasic oral contraceptive containing low doses of ethynyl estradiol and d,l-norgestrel","volume":"71","author":"Lemay","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.contraception.2005.07.010_bib3","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0010-7824(99)00093-1","article-title":"Effect of low-dose oral contraceptives on androgenic markers and acne","volume":"60","author":"Thorneycroft","year":"1999","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2005.07.010_bib4","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1067\/mjd.2002.122192","article-title":"Efficacy of a low-dose oral contraceptive containing 20 \u03bcg of ethinyl estradiol and 100 \u03bcg of levonorgestrel for the treatment of moderate acne: a randomized, placebo-controlled trial","volume":"47","author":"Leyden","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.contraception.2005.07.010_bib5","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1159\/000051701","article-title":"Acne resolution rates: results of a single-blind, randomized, controlled, parallel phase III trial with EE\/CMA (Belara) and EE\/LNG (Microgynon)","volume":"203","author":"Worret","year":"2001","journal-title":"Dermatology"},{"key":"10.1016\/j.contraception.2005.07.010_bib6","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0015-0282(01)01938-0","article-title":"A randomized, controlled trial of a low-dose contraceptive containing 20 \u03bcg of ethinyl estradiol and 100 \u03bcg of levonorgestrel for acne treatment","volume":"76","author":"Thiboutot","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.contraception.2005.07.010_bib7","series-title":"Update on triphasic oral contraception. Proceedings from a symposium preceding the 10th World Congress on Obstetrics and Gynecology, San Francisco, 17 October 1982","first-page":"54","article-title":"Clinical experience with the triphasic oral contraceptive","author":"Upton","year":"1983"},{"key":"10.1016\/j.contraception.2005.07.010_bib8","first-page":"932","article-title":"Clinical evaluation of a monophasic ethinylestradiol\/desogestrel-containing oral contraceptive","volume":"38","author":"Bilotta","year":"1988","journal-title":"Drug Res"},{"issue":"Suppl. 156","key":"10.1016\/j.contraception.2005.07.010_bib9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3109\/00016349209156510","article-title":"Selectivity and minimal androgenicity of norgestimate in monophasic and triphasic oral contraceptives","volume":"71","author":"Anderson","year":"1992","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.contraception.2005.07.010_bib10","series-title":"Update on triphasic oral contraception. Proceedings from a symposium preceding the 10th World Congress on Obstetrics and Gynecology, San Francisco, 17 October 1982","first-page":"75","article-title":"The effect of the triphasic oral contraceptive on acne vulgaris: an interim report of an open multicenter study","author":"Loudon","year":"1983"},{"key":"10.1016\/j.contraception.2005.07.010_bib11","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1080\/ejc.6.2.108.114","article-title":"A large observational clinical evaluation of a desogestrel-containing combiphasic oral contraceptive in Germany","volume":"6","author":"Vree","year":"2001","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2005.07.010_bib12","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0010-7824(03)00167-7","article-title":"Effects of a phasic oral contraceptive containing desogestrel on facial seborrhea and acne","volume":"68","author":"Prilepskaya","year":"2003","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2005.07.010_bib13","first-page":"283","article-title":"Acne treatment with a new estroprogestinic biphasic combination containing desogestrel","volume":"22","author":"Falsetti","year":"1991","journal-title":"Acta Eur Fertil"},{"key":"10.1016\/j.contraception.2005.07.010_bib14","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1159\/000068893","article-title":"Clinical evidence of the endocrinological influence of a triphasic oral contraceptive containing norgestimate and ethinyl estradiol in treating women with acne vulgaris","volume":"206","author":"Sator","year":"2003","journal-title":"Dermatology"},{"key":"10.1016\/j.contraception.2005.07.010_bib15","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/13625180008500405","article-title":"A quantitative biometrological assessment of acne and hormonal evaluation in young women using a triphasic low-dose oral contraceptive containing gestodene","volume":"5","author":"Pi\u00e9rard-Franchimont","year":"2000","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2005.07.010_bib16","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1742-1241.2000.tb11855.x","article-title":"The effects of Valette on skin and hair: a post-marketing surveillance study","volume":"54","author":"Zimmerman","year":"2000","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.contraception.2005.07.010_bib17","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/j.1365-2133.1986.tb04880.x","article-title":"Anti-androgen treatment in women with acne: a controlled trial","volume":"114","author":"Miller","year":"1986","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.contraception.2005.07.010_bib18","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3109\/00016348609157049","article-title":"Cyproterone acetate versus levonorgestrel combined with ethinyl estradiol in the treatment of acne. Results of a multicenter study","volume":"134","author":"Carlborg","year":"1986","journal-title":"Acta Obstet Gynecol Scand Suppl"},{"key":"10.1016\/j.contraception.2005.07.010_bib19","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1440-0960.1991.tb00683.x","article-title":"An open study of Triphasil and Diane 50 in the treatment of acne","volume":"32","author":"Wishart","year":"1991","journal-title":"Aust J Dermatol"},{"key":"10.1016\/j.contraception.2005.07.010_bib20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3109\/00016349009021041","article-title":"Ovulation inhibitors containing cyproterone acetate or desogestrel in the treatment of hyperandrogenic symptoms","volume":"69","author":"Erkkola","year":"1990","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.contraception.2005.07.010_bib21","first-page":"423","article-title":"Effects on acne of two oral contraceptives containing desogestrel and cyproterone acetate","volume":"41","author":"Charoenvisal","year":"1996","journal-title":"Int J Fertil Menopausal Stud"},{"key":"10.1016\/j.contraception.2005.07.010_bib22","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/ejc.6.1.46.53","article-title":"Comparison of the effect on acne with a combiphasic desogestrel-containing oral contraceptive and a preparation containing cyproterone acetate","volume":"6","author":"Vartiainen","year":"2001","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2005.07.010_bib23","first-page":"573","article-title":"Efficacit\u00e9 sur l'acn\u00e9 des contraceptifs oraux","volume":"83","author":"Levrier","year":"1988","journal-title":"Rev Fr Gyn\u00e9col Obst\u00e9t"},{"key":"10.1016\/j.contraception.2005.07.010_bib24","first-page":"2","article-title":"The effect of 2 combined oral contraceptives containing either drospirenone or cyproterone acetate on acne and seborrhea","volume":"69","author":"van Vloten","year":"2002","journal-title":"Cutis"},{"key":"10.1016\/j.contraception.2005.07.010_bib25","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0010-7824(96)00005-4","article-title":"Clinical and hormonal effects of ethinylestradiol combined with gestodene and desogestrel in young women with acne vulgaris","volume":"53","author":"Mango","year":"1996","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2005.07.010_bib26","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2340\/0001555564517523","article-title":"Serum total and unbound testosterone and sex hormone binding globulin (SHBG) in female acne patients treated with two different oral contraceptives","volume":"64","author":"Palatsi","year":"1984","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.contraception.2005.07.010_bib27","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1067\/mob.2003.294","article-title":"A randomized controlled trial of second- and third-generation oral contraceptives in the treatment of acne vulgaris","volume":"188","author":"Rosen","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.contraception.2005.07.010_bib28","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.contraception.2003.12.017","article-title":"Cycle control, quality of life and acne with two low-dose oral contraceptives containing 20 \u03bcg ethinylestradiol","volume":"69","author":"Winkler","year":"2004","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2005.07.010_bib29","first-page":"123","article-title":"Superiority of a combined contraceptive containing drospirenone to a triphasic preparation containing norgestimate in acne treatment","volume":"74","author":"Thorneycroft","year":"2004","journal-title":"Cutis"},{"key":"10.1016\/j.contraception.2005.07.010_bib30","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0010-7824(99)00069-4","article-title":"Use of placebo controls in an oral contraceptive trial: methodological issues and adverse event incidence","volume":"60","author":"Redmond","year":"1999","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2005.07.010_bib31","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S0029-7844(97)00059-8","article-title":"Norgestimate and ethinyl estradiol in the treatment of acne vulgaris: a randomized, placebo-controlled trial","volume":"89","author":"Redmond","year":"1997","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.contraception.2005.07.010_bib32","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0190-9622(97)70112-9","article-title":"Effectiveness of norgestimate and ethinyl estradiol in treating moderate acne vulgaris","volume":"37","author":"Lucky","year":"1997","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.contraception.2005.07.010_bib33","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1053\/cjwh.2001.25638","article-title":"Use of a low-dose oral contraceptive containing norethindrone acetate and ethinyl estradiol in the treatment of moderate acne vulgaris","volume":"2","author":"Maloney","year":"2001","journal-title":"Clin J Women's Health"},{"key":"10.1016\/j.contraception.2005.07.010_bib34","first-page":"619","article-title":"Steroid contraception and the risk of neoplasia. Report of a WHO Scientific Group","author":"World Health Organization","year":"1978","journal-title":"World Health Organ Tech Rep Ser"},{"key":"10.1016\/j.contraception.2005.07.010_bib35","series-title":"Contraceptive technology","first-page":"405","article-title":"The Pill: combined oral contraceptives","author":"Hatcher","year":"1998"},{"key":"10.1016\/j.contraception.2005.07.010_bib36","article-title":"Understanding low dose oral contraceptives","author":"Creinin","year":"2001"},{"key":"10.1016\/j.contraception.2005.07.010_bib37","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0010-7824(99)00109-2","article-title":"Efficacy, cycle control, and side effects of low- and lower-dose oral contraceptives: a randomized trial of 20 \u03bcg and 35 \u03bcg estrogen preparations","volume":"60","author":"Rosenberg","year":"2000","journal-title":"Contraception"}],"container-title":["Contraception"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001078240500301X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001078240500301X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T10:22:20Z","timestamp":1706610140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001078240500301X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S001078240500301X"],"URL":"https:\/\/doi.org\/10.1016\/j.contraception.2005.07.010","relation":{},"ISSN":["0010-7824"],"issn-type":[{"value":"0010-7824","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}