{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T12:49:23Z","timestamp":1785761363482,"version":"3.56.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","contraceptionjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contraception"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1016\/j.contraception.2007.08.004","type":"journal-article","created":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T01:05:36Z","timestamp":1196471136000},"page":"461-466","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["A randomized comparison of misoprostol to intrauterine instillation of hypertonic saline plus a prostaglandin F2\u03b1 analogue for second-trimester induction termination in Uzbekistan"],"prefix":"10.1016","volume":"76","author":[{"given":"Nathalie","family":"Kapp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine S.","family":"Todd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klara T.","family":"Yadgarova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulchaekra","family":"Alibayeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilyora","family":"Nazarova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oralia","family":"Loza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guldjahan S.","family":"Babadjanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.contraception.2007.08.004_bib1","author":"Alan Guttmacher Institute"},{"key":"10.1016\/j.contraception.2007.08.004_bib2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.2307\/3180995","article-title":"Relationships between contraception and abortion: a review of the evidence","volume":"29","author":"Marston","year":"2003","journal-title":"Int Fam Plann Perspect"},{"key":"10.1016\/j.contraception.2007.08.004_bib3","author":"Population Resource Center"},{"key":"10.1016\/j.contraception.2007.08.004_bib4","first-page":"505","article-title":"Morbidity and mortality from second-trimester abortions","volume":"30","author":"Grimes","year":"1985","journal-title":"J Reprod Med"},{"key":"10.1016\/j.contraception.2007.08.004_bib5","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/j.1879-3479.1977.tb00673.x","article-title":"Methods of midtrimester terminations, which is safest?","volume":"15","author":"Grimes","year":"1977","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.contraception.2007.08.004_bib6","first-page":"1","article-title":"Abortion surveillance \u2014 United States, 1998","volume":"51","author":"Herndon","year":"2002","journal-title":"Morb Mortal Wkly Rep Surveill Summ"},{"key":"10.1016\/j.contraception.2007.08.004_bib7","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1001\/jama.1982.03330050041028","article-title":"Dilatation and evacuation procedures and second-trimester abortions. The role of physician skill and hospital setting","volume":"248","author":"Cates","year":"1982","journal-title":"JAMA"},{"key":"10.1016\/j.contraception.2007.08.004_bib8","doi-asserted-by":"crossref","first-page":"128","DOI":"10.2307\/1965604","article-title":"Dilatation and evacuation for induced abortion in developing countries: advantages and disadvantages","volume":"11","author":"Cates","year":"1980","journal-title":"Stud Fam Plann"},{"key":"10.1016\/j.contraception.2007.08.004_bib9","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/0002-9378(83)90971-7","article-title":"Urea-prostaglandin versus hypertonic saline for instillation abortion","volume":"146","author":"Binkin","year":"1983","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.contraception.2007.08.004_bib10","first-page":"88","article-title":"Early complications and sequence of pregnancy interruption with hypertonic saline","volume":"25","author":"Borenstein","year":"1980","journal-title":"Int J Fertil"},{"key":"10.1016\/j.contraception.2007.08.004_bib11","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1046\/j.1471-0528.2003.00044.x-i1","article-title":"Mifepristone and misoprostol versus dilation and evacuation for midtrimester abortion: a pilot randomised controlled trial","volume":"11","author":"Grimes","year":"2004","journal-title":"BJOG"},{"key":"10.1016\/j.contraception.2007.08.004_bib12","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1056\/NEJM200101043440107","article-title":"Misoprostol and pregnancy","volume":"344","author":"Goldberg","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.contraception.2007.08.004_bib13","first-page":"102","article-title":"The visual analog scale in the immediate postoperative period: intraparticipant variability and correlation with a numeric scale","volume":"86","author":"DeLoach","year":"1998","journal-title":"Anesth Analg"},{"key":"10.1016\/j.contraception.2007.08.004_bib14","first-page":"237","article-title":"Comparative study of midtrimester termination of pregnancy using hypertonic saline, ethacridine lactate, prostaglandin analogue and iodine-saline","volume":"90","author":"Allahbadia","year":"1992","journal-title":"J Indian Med Assoc"},{"key":"10.1016\/j.contraception.2007.08.004_bib15","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0028-2243(79)90132-1","article-title":"Use of prostaglandin, hypertonic saline and oxytocin for second-trimester abortion","volume":"9","author":"Muzsnai","year":"1979","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.contraception.2007.08.004_bib16","first-page":"148","article-title":"Mid-trimester abortion using hypertonic saline or prostaglandin E2 gel: an analysis of efficacy and complications","volume":"77","author":"Herabutya","year":"1994","journal-title":"J Med Assoc Thai"},{"key":"10.1016\/j.contraception.2007.08.004_bib17","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1111\/j.1471-0528.2005.00727.x","article-title":"A randomised controlled trial of 6 and 12 hourly administration of vaginal misoprostol for second trimester pregnancy termination","volume":"112","author":"Herabutya","year":"2005","journal-title":"BJOG"},{"key":"10.1016\/j.contraception.2007.08.004_bib18","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1067\/mob.2002.127461","article-title":"A randomized controlled trial comparing two protocols for the use of misoprostol in midtrimester pregnancy termination","volume":"187","author":"Bebbington","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.contraception.2007.08.004_bib19","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1093\/humrep\/dei204","article-title":"Misoprostol moistened with acetic acid or saline for second trimester pregnancy termination: a randomized prospective double-blind trial","volume":"20","author":"Yilmaz","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.contraception.2007.08.004_bib20","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.contraception.2005.04.016","article-title":"A randomized clinical trial of the addition of laminaria to misoprostol and hypertonic saline for second-trimester induction abortion","volume":"72","author":"Borgatta","year":"2005","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2007.08.004_bib21","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1056\/NEJM199408043310502","article-title":"A comparison of intravaginal misoprostol with prostaglandin E2 for termination of second-trimester pregnancy","volume":"331","author":"Jain","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1016\/j.contraception.2007.08.004_bib22","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ijgo.2005.06.012","article-title":"Abortion procedures in a tertiary care institution in India","volume":"91","author":"Choudhary","year":"2005","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.contraception.2007.08.004_bib23","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/13625180410001696232","article-title":"Frequent low-dose misoprostol for termination of second-trimester pregnancy","volume":"1","author":"Dilbaz","year":"2004","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2007.08.004_bib24","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0010-7824(01)00193-7","article-title":"Early pregnancy termination with vaginal misoprostol combined with loperamide and acetaminophen prophylaxis","volume":"63","author":"Jain","year":"2001","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2007.08.004_bib25","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/0002-9378(86)90173-0","article-title":"Acetaminophen pharmacokinetics: comparison between pregnant and nonpregnant women","volume":"155","author":"Rayburn","year":"1986","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.contraception.2007.08.004_bib26","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0029-7844(97)00111-7","article-title":"Absorption kinetics of misoprostol with oral or vaginal administration","volume":"90","author":"Zieman","year":"1997","journal-title":"Obstet Gynecol"}],"container-title":["Contraception"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010782407004076?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010782407004076?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T21:09:16Z","timestamp":1762117756000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0010782407004076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["S0010782407004076"],"URL":"https:\/\/doi.org\/10.1016\/j.contraception.2007.08.004","relation":{},"ISSN":["0010-7824"],"issn-type":[{"value":"0010-7824","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A randomized comparison of misoprostol to intrauterine instillation of hypertonic saline plus a prostaglandin F2\u03b1 analogue for second-trimester induction termination in Uzbekistan","name":"articletitle","label":"Article Title"},{"value":"Contraception","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.contraception.2007.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}