{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T22:17:28Z","timestamp":1789597048492,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contraception"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1016\/j.contraception.2010.03.006","type":"journal-article","created":{"date-parts":[[2010,4,14]],"date-time":"2010-04-14T08:26:12Z","timestamp":1271233572000},"page":"266-275","source":"Crossref","is-referenced-by-count":21,"title":["Comparison of two dose regimens of misoprostol for second-trimester pregnancy termination"],"prefix":"10.1016","volume":"82","author":[{"given":"Joseph Franciscus Gertrudis Maria","family":"Brouns","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madelon","family":"van Wely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattheus Petrus Maria","family":"Burger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem Jacobus","family":"van Wijngaarden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.contraception.2010.03.006_bib1","series-title":"The care of women requesting induced abortion","author":"The Royal College of Obstetricians and Gynaecologists","year":"2004"},{"key":"10.1016\/j.contraception.2010.03.006_bib2","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/j.1471-0528.1999.tb08371.x","article-title":"Nonsurgical mid-trimester termination of pregnancy: a review of 500 consecutive cases","volume":"106","author":"Ashok","year":"1999","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib3","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1093\/humrep\/dei037","article-title":"A randomized trial of mifepristone in combination with misoprostol administered sublingually or vaginally for medical abortion at 13-20 weeks gestation","volume":"20","author":"Hamoda","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.contraception.2010.03.006_bib4","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0029-7844(98)00436-0","article-title":"Comparison between oral and vaginal administration of misoprostol on uterine contractility","volume":"93","author":"Danielsson","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib5","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/S0029-7844(03)00357-0","article-title":"A comparison of oral misoprostol with vaginal misoprostol administration in second-trimester pregnancy termination for fetal abnormality","volume":"101","author":"Dickinson","year":"2003","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib6","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/j.1479-828X.2001.tb01318.x","article-title":"A randomised trial of oral versus vaginal administration of misoprostol for the purpose of mid-trimester termination of pregnancy","volume":"41","author":"Gilbert","year":"2001","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib7","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1111\/j.1471-0528.2004.00222.x","article-title":"A prospective randomised comparison of sublingual and vaginal misoprostol in second trimester termination of pregnancy","volume":"111","author":"Tang","year":"2004","journal-title":"BJOG"},{"key":"10.1016\/j.contraception.2010.03.006_bib8","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1093\/humrep\/17.2.332","article-title":"Pharmacokinetics of different routes of administration of misoprostol","volume":"17","author":"Tang","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.contraception.2010.03.006_bib9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.contraception.2006.03.005","article-title":"The pharmacokinetics and different regimens of misoprostol in early first-trimester medical abortion","volume":"74","author":"Tang","year":"2006","journal-title":"Contraception"},{"issue":"Suppl 2","key":"10.1016\/j.contraception.2010.03.006_bib10","doi-asserted-by":"crossref","first-page":"S160","DOI":"10.1016\/j.ijgo.2007.09.004","article-title":"Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects","volume":"99","author":"Tang","year":"2007","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.contraception.2010.03.006_bib11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0020-7292(97)00244-0","article-title":"Second trimester abortion using intravaginal misoprostol","volume":"60","author":"Herabutya","year":"1998","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.contraception.2010.03.006_bib12","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0029-7844(97)00419-5","article-title":"Vaginal misoprostol compared with oral misoprostol in termination of second-trimester pregnancy","volume":"90","author":"Ho","year":"1997","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib13","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1093\/humrep\/den425","article-title":"A randomized trial to compare two dosing intervals of misoprostol following mifepristone administration in second trimester medical abortion","volume":"24","author":"Chai","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.contraception.2010.03.006_bib14","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1097\/01.AOG.0000289577.32274.a5","article-title":"Mifepristone in second-trimester medical abortion: a randomized controlled trial","volume":"110","author":"Kapp","year":"2007","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib15","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/j.1471-0528.1996.tb09842.x","article-title":"A comparison of 600 and 200 mg mifepristone prior to second trimester abortion with the prostaglandin misoprostol","volume":"103","author":"Webster","year":"1996","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib16","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.contraception.2003.09.006","article-title":"Midtrimester medical termination of pregnancy: a review of 1002 consecutive cases","volume":"69","author":"Ashok","year":"2004","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2010.03.006_bib17","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1093\/humrep\/15.10.2205","article-title":"Randomized comparison of vaginal (200 microg every 3 h) and oral (400 microg every 3 h) misoprostol when combined with mifepristone in termination of second trimester pregnancy","volume":"15","author":"Ngai","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1016\/j.contraception.2010.03.006_bib18","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0010-7824(02)00492-4","article-title":"The learning curve is rapid in medical termination of pregnancy \u2014 first-year results from the Helsinki area","volume":"67","author":"Suhonen","year":"2003","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2010.03.006_bib19","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1067\/mob.2002.121085","article-title":"The optimization of intravaginal misoprostol dosing schedules in second-trimester pregnancy termination","volume":"186","author":"Dickinson","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib20","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0002-9378(96)70270-3","article-title":"A comparison of misoprostol with and without laminaria tents for induction of second-trimester abortion","volume":"175","author":"Jain","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.contraception.2010.03.006_bib21","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1080\/00016340601002282","article-title":"Two regimens of vaginal misoprostol in second trimester termination of pregnancy: a prospective randomised trial","volume":"85","author":"Bhattacharyya","year":"2006","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.contraception.2010.03.006_bib22","doi-asserted-by":"crossref","first-page":"3062","DOI":"10.1093\/humrep\/dei196","article-title":"A prospective randomized comparison of sublingual and oral misoprostol when combined with mifepristone for medical abortion at 12-20 weeks gestation","volume":"20","author":"Tang","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.contraception.2010.03.006_bib23","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/j.1471-0528.2005.00648.x","article-title":"Neonatal death following termination of pregnancy","volume":"112","author":"Vadeyar","year":"2005","journal-title":"BJOG"},{"key":"10.1016\/j.contraception.2010.03.006_bib24","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1056\/NEJM200101043440107","article-title":"Misoprostol and pregnancy 4","volume":"344","author":"Goldberg","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.contraception.2010.03.006_bib25","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1056\/NEJM200107053450101","article-title":"Risk of uterine rupture during labor among women with a prior cesarean delivery1","volume":"345","author":"Lydon-Rochelle","year":"2001","journal-title":"N Engl J Med"}],"container-title":["Contraception"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001078241000096X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001078241000096X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T23:53:43Z","timestamp":1544572423000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001078241000096X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S001078241000096X"],"URL":"https:\/\/doi.org\/10.1016\/j.contraception.2010.03.006","relation":{},"ISSN":["0010-7824"],"issn-type":[{"value":"0010-7824","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}