{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:30:34Z","timestamp":1761676234563,"version":"3.40.5"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["contraceptionjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contraception"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.contraception.2014.11.002","type":"journal-article","created":{"date-parts":[[2014,11,16]],"date-time":"2014-11-16T20:27:43Z","timestamp":1416169663000},"page":"127-133","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: I. Endocrine effects"],"prefix":"10.1016","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3446-1716","authenticated-orcid":false,"given":"Y.","family":"Zimmerman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-M.","family":"Foidart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2562-2071","authenticated-orcid":false,"given":"A.","family":"Pintiaux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.-M.","family":"Minon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.C.J.M.","family":"Fauser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2797-1686","authenticated-orcid":false,"given":"K.","family":"Cobey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.J.T.","family":"Coelingh Bennink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.contraception.2014.11.002_bb0005","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/humupd\/dmt038","article-title":"The effect of combined oral contraception on testosterone levels in healthy women: a systematic review and meta-analysis","volume":"20","author":"Zimmerman","year":"2014","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.contraception.2014.11.002_bb0010","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0010-7824(96)00006-6","article-title":"Changes in androgens during treatment with four low-dose contraceptives","volume":"53","author":"Coenen","year":"1996","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2014.11.002_bb0015","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S0015-0282(02)02969-2","article-title":"Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment","volume":"77","author":"Bachmann","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.contraception.2014.11.002_bb0020","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1111\/j.1743-6109.2007.00584.x","article-title":"Are the Endocrine Society's Clinical Practice Guidelines on Androgen Therapy in Women misguided? A commentary","volume":"4","author":"Traish","year":"2007","journal-title":"J Sex Med"},{"key":"10.1016\/j.contraception.2014.11.002_bb0025","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.psyneuen.2012.11.006","article-title":"Oral contraceptive use changes brain activity and mood in women with previous negative affect on the pill-a double-blinded, placebo-controlled randomized trial of a levonorgestrel-containing combined oral contraceptive","volume":"38","author":"Gingnell","year":"2013","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.contraception.2014.11.002_bb0030","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0010-7824(99)00034-7","article-title":"Women's satisfaction with birth control: a population survey of physical and psychological effects of oral contraceptives, intrauterine devices, condoms, natural family planning, and sterilization among 1466 women","volume":"59","author":"Oddens","year":"1999","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2014.11.002_bb0035","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0010-7824(01)00218-9","article-title":"A prospective study of the effects of oral contraceptives on sexuality and well-being and their relationship to discontinuation","volume":"64","author":"Sanders","year":"2001","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2014.11.002_bb0040","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.contraception.2009.12.022","article-title":"Effects of sex hormones in oral contraceptives on the female sexual function score: a study in German female medical students","volume":"82","author":"Wallwiener","year":"2010","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2014.11.002_bb0045","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1210\/jcem.83.6.4850","article-title":"Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression","volume":"83","author":"Arlt","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.contraception.2014.11.002_bb0050","first-page":"3208","article-title":"Dehydroepiandrosterone replacement administration: pharmacokinetic and pharmacodynamic studies in healthy elderly subjects","volume":"85","author":"Legrain","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.contraception.2014.11.002_bb0055","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1177\/00912700122012742","article-title":"Effects of oral prasterone (dehydroepiandrosterone) on single-dose pharmacokinetics of oral prednisone and cortisol suppression in normal women","volume":"41","author":"Meno-Tetang","year":"2001","journal-title":"J Clin Pharmacol"},{"key":"10.1016\/j.contraception.2014.11.002_bb0060","first-page":"1360","article-title":"Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age","volume":"78","author":"Morales","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.contraception.2014.11.002_bb0065","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.contraception.2014.11.008","article-title":"Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: II Clinical effects","volume":"91","author":"Zimmerman","year":"2015","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2014.11.002_bb0070","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/tre.113","article-title":"Welcome developments in contraception","volume":"14","author":"Mansour","year":"2009","journal-title":"Trends Urol Gynaecol Sex Health"},{"key":"10.1016\/j.contraception.2014.11.002_bb0075","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/0022-4731(82)90038-3","article-title":"Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature","volume":"16","author":"Sodergard","year":"1982","journal-title":"J Steroid Biochem"},{"key":"10.1016\/j.contraception.2014.11.002_bb0080","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.1210\/jcem.84.10.6079","article-title":"A critical evaluation of simple methods for the estimation of free testosterone in serum","volume":"84","author":"Vermeulen","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.contraception.2014.11.002_bb0085","doi-asserted-by":"crossref","first-page":"458","DOI":"10.3109\/13625187.2011.614363","article-title":"Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17beta-oestradiol in comparison to one containing levonorgestrel and ethinylestradiol on markers of endocrine function","volume":"16","author":"\u00c5gren","year":"2011","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2014.11.002_bb0090","doi-asserted-by":"crossref","first-page":"314","DOI":"10.3109\/13625187.2010.504313","article-title":"Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17 beta-oestradiol on ovarian function in comparison to a monophasic combined oral contraceptive containing drospirenone and ethinylestradiol","volume":"15","author":"Duijkers","year":"2010","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2014.11.002_bb0095","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1210\/jc.2011-2134","article-title":"Age-specific reference ranges for serum testosterone and androstenedione concentrations in women measured by liquid chromatography-tandem mass spectrometry","volume":"97","author":"Haring","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.contraception.2014.11.002_bb0100","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0010-7824(95)00098-U","article-title":"Effect of two oral contraceptives containing ethinylestradiol and gestodene or norgestimate upon androgen parameters and serum binding proteins","volume":"51","author":"Wiegratz","year":"1995","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2014.11.002_bb0105","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0010-7824(02)00436-5","article-title":"Effect of four different oral contraceptives on various sex hormones and serum-binding globulins","volume":"67","author":"Wiegratz","year":"2003","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2014.11.002_bb0110","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.cca.2013.12.042","article-title":"Peculiar observations in measuring testosterone in women treated with oral contraceptives supplemented with dehydroepiandrosterone (DHEA)","volume":"430","author":"Heijboer","year":"2014","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.contraception.2014.11.002_bb0115","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/0002-9378(82)90231-9","article-title":"Changes in unbound sex steroids and sex hormone binding globulin-binding capacity during oral and vaginal progestogen administration","volume":"144","author":"Granger","year":"1982","journal-title":"Am J Obstet Gynecol"},{"year":"2005","series-title":"Clinical gynecologic endocrinology and infertility","author":"Speroff","key":"10.1016\/j.contraception.2014.11.002_bb0120"},{"issue":"Suppl. 4","key":"10.1016\/j.contraception.2014.11.002_bb0125","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S0015-0282(02)02985-0","article-title":"Androgen production in women","volume":"77","author":"Burger","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.contraception.2014.11.002_bb0130","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1373\/clinchem.2011.181735","article-title":"Accuracy of first and second generation testosterone assays and improvement through sample extraction","volume":"58","author":"Groenestege","year":"2012","journal-title":"Clin Chem"},{"key":"10.1016\/j.contraception.2014.11.002_bb0135","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1373\/49.8.1381","article-title":"Testosterone measured by 10 immunoassays and by isotope-dilution gas chromatography\u2013mass spectrometry in sera from 116 men, women, and children","volume":"49","author":"Taieb","year":"2003","journal-title":"Clin Chem"},{"key":"10.1016\/j.contraception.2014.11.002_bb0140","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1210\/jc.2003-030680","article-title":"Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods","volume":"89","author":"Miller","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"year":"2012","series-title":"Tietz textbook of clinical chemistry and molecular diagnostics","key":"10.1016\/j.contraception.2014.11.002_bb0145"},{"key":"10.1016\/j.contraception.2014.11.002_bb0150","first-page":"1065","article-title":"Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations","volume":"11","author":"Rinaldi","year":"2002","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.contraception.2014.11.002_bb0155","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1080\/00365510260296519","article-title":"Diurnal rhythm and effects of oral contraceptives on serum dehydroepiandrosterone sulfate (DHEAS) are related to alterations in serum albumin rather than to changes in adrenocortical steroid secretion","volume":"62","author":"Carlstrom","year":"2002","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1016\/j.contraception.2014.11.002_bb0160","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S0015-0282(16)47956-2","article-title":"Serum steroid binding protein concentrations, distribution of progestogens, and bioavailability of testosterone during treatment with contraceptives containing desogestrel or levonorgestrel","volume":"42","author":"Hammond","year":"1984","journal-title":"Fertil Steril"},{"key":"10.1016\/j.contraception.2014.11.002_bb0165","doi-asserted-by":"crossref","first-page":"949","DOI":"10.2165\/00002512-200320130-00001","article-title":"Pharmacology and therapeutic effects of dehydroepiandrosterone in older subjects","volume":"20","author":"Legrain","year":"2003","journal-title":"Drugs Aging"}],"container-title":["Contraception"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010782414007513?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010782414007513?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T09:02:02Z","timestamp":1566032522000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0010782414007513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S0010782414007513"],"URL":"https:\/\/doi.org\/10.1016\/j.contraception.2014.11.002","relation":{},"ISSN":["0010-7824"],"issn-type":[{"type":"print","value":"0010-7824"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: I. Endocrine effects","name":"articletitle","label":"Article Title"},{"value":"Contraception","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.contraception.2014.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}