{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:06:25Z","timestamp":1788869185320,"version":"build-2803163510"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","contraceptionjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Contraception"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.contraception.2025.111201","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T00:06:54Z","timestamp":1757030814000},"page":"111201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Real-world validation of a bleeding prediction algorithm in levonorgestrel intrauterine device users using the MyIUS mobile app"],"prefix":"10.1016","volume":"152","author":[{"given":"Carolina Sales","family":"Vieira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Eggebrecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor Andre","family":"Milhoranca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Schiffer","family":"Acar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"von Stockum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann-Kathrin","family":"Frenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.contraception.2025.111201_bib1","doi-asserted-by":"crossref","DOI":"10.1186\/s12905-022-01657-6","article-title":"Discontinuation rates of intrauterine contraception due to unfavourable bleeding: a systematic review","volume":"22","author":"Costescu","year":"2022","journal-title":"BMC Womens Health"},{"key":"10.1016\/j.contraception.2025.111201_bib2","doi-asserted-by":"crossref","DOI":"10.1186\/s12978-018-0561-0","article-title":"There might be blood: a scoping review on women's responses to contraceptive-induced menstrual bleeding changes","volume":"15","author":"Polis","year":"2018","journal-title":"Reprod Health"},{"key":"10.1016\/j.contraception.2025.111201_bib3","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0010-7824(96)00189-8","article-title":"Detailed analysis of menstrual bleeding patterns after postmenstrual and postabortal insertion of a copper IUD or a levonorgestrel-releasing intrauterine system","volume":"54","author":"Suvisaari","year":"1996","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2025.111201_bib4","article-title":"The use of LNG-IUS-19.5 mg in daily gynecological routine practice in Germany: data from the kyleena\u2122 satisfaction study (KYSS)","volume":"309","author":"R\u00f6mer","year":"2024","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.contraception.2025.111201_bib5","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.contraception.2019.03.044","article-title":"Comparing bleeding patterns for the levonorgestrel 52 mg, 19.5 mg, and 13.5 mg intrauterine systems","volume":"100","author":"Goldthwaite","year":"2019","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2025.111201_bib6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.contraception.2022.05.011","article-title":"Recommendations for standardization of bleeding data analyses in contraceptive studies","volume":"112","author":"Creinin","year":"2022","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2025.111201_bib7","doi-asserted-by":"crossref","DOI":"10.2196\/24633","article-title":"Digital medical device companion (MyIUS) for new users of intrauterine systems: app development study","volume":"9","author":"Karakoyun","year":"2021","journal-title":"JMIR Med Inform"},{"key":"10.1016\/j.contraception.2025.111201_bib8","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.fertnstert.2011.12.003","article-title":"A randomized, phase II study describing the efficacy, bleeding profile, and safety of two low-dose levonorgestrel-releasing intrauterine contraceptive systems and mirena","volume":"97","author":"Gemzell-Danielsson","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.contraception.2025.111201_bib9","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1097\/AOG.0000000000000019","article-title":"Two low-dose levonorgestrel intrauterine contraceptive systems: a randomized controlled trial","volume":"122","author":"Nelson","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.contraception.2025.111201_bib10","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1080\/13625187.2020.1843015","article-title":"Predicting menstrual bleeding patterns with levonorgestrel-releasing intrauterine systems","volume":"26","author":"Frenz","year":"2021","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2025.111201_bib11","first-page":"5","article-title":"Random forests","volume":"45","author":"Breiman","year":"2001","journal-title":"Mach\u00a0Learn"},{"key":"10.1016\/j.contraception.2025.111201_bib12","first-page":"267","article-title":"Regression shrinkage and selection via the lasso","volume":"58","author":"Tibshirani","year":"1996","journal-title":"J\u00a0R\u00a0Stat\u00a0Soc"},{"key":"10.1016\/j.contraception.2025.111201_bib13","first-page":"171","article-title":"A simple generalisation of the area under the ROC curve for multiple class classification problems","volume":"45","author":"Hand","year":"2001","journal-title":"Mach\u00a0Learn"},{"key":"10.1016\/j.contraception.2025.111201_bib14","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1097\/JTO.0b013e3181ec173d","article-title":"Receiver operating characteristic curve in diagnostic test assessment","volume":"5","author":"Mandrekar","year":"2010","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.contraception.2025.111201_bib15","series-title":"Applied logistic regression","author":"Hosmer","year":"2013"},{"key":"10.1016\/j.contraception.2025.111201_bib16","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/13625187.2019.1630817","article-title":"Bleeding patterns with the 19.5 mg LNG-IUS, with special focus on the first year of use: implications for counselling","volume":"24","author":"Beckert","year":"2019","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2025.111201_bib17","doi-asserted-by":"crossref","first-page":"50.e1","DOI":"10.1016\/j.ajog.2014.07.025","article-title":"Association of short-term bleeding and cramping patterns with long-acting reversible contraceptive method satisfaction","volume":"212","author":"Diedrich","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.contraception.2025.111201_bib18","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.contraception.2019.05.017","article-title":"Can initial vaginal bleeding patterns in etonogestrel implant users predict subsequent bleeding in the first 2 years of use?","volume":"100","author":"Mansour","year":"2019","journal-title":"Contraception"},{"key":"10.1016\/j.contraception.2025.111201_bib19","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3109\/13625187.2013.853034","article-title":"A three-year comparative study of continuation rates, bleeding patterns and satisfaction in Australian women using a subdermal contraceptive implant or progestogen releasing-intrauterine system","volume":"19","author":"Weisberg","year":"2014","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.contraception.2025.111201_bib20","doi-asserted-by":"crossref","DOI":"10.12688\/gatesopenres.13609.1","article-title":"Global research and learning agenda for building evidence on contraceptive-induced menstrual changes for research, product development, policies, and programs","volume":"6","author":"Hoppes","year":"2022","journal-title":"Gates Open Res"},{"key":"10.1016\/j.contraception.2025.111201_bib21","doi-asserted-by":"crossref","DOI":"10.1186\/s12978-023-01573-4","article-title":"Assessing contraceptive use as a continuum: outcomes of a qualitative assessment of the contraceptive journey","volume":"20","author":"Simmons","year":"2023","journal-title":"Reprod Health"},{"key":"10.1016\/j.contraception.2025.111201_bib22","doi-asserted-by":"crossref","first-page":"589","DOI":"10.2147\/IJWH.S99705","article-title":"Levonorgestrel-releasing intrauterine systems for long-acting contraception: current perspectives, safety, and patient counseling","volume":"8","author":"Costescu","year":"2016","journal-title":"Int J Womens Health"}],"container-title":["Contraception"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010782425003920?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010782425003920?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T04:25:26Z","timestamp":1780201526000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0010782425003920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":22,"alternative-id":["S0010782425003920"],"URL":"https:\/\/doi.org\/10.1016\/j.contraception.2025.111201","relation":{},"ISSN":["0010-7824"],"issn-type":[{"value":"0010-7824","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Real-world validation of a bleeding prediction algorithm in levonorgestrel intrauterine device users using the MyIUS mobile app","name":"articletitle","label":"Article Title"},{"value":"Contraception","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.contraception.2025.111201","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111201"}}