{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:03:17Z","timestamp":1792627397266,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,8,28]],"date-time":"2017-08-28T00:00:00Z","timestamp":1503878400000},"content-version":"am","delay-in-days":270,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U50\/CCU116806-01-1"],"award-info":[{"award-number":["U50\/CCU116806-01-1"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"US Department of Agriculture","doi-asserted-by":"publisher","award":["CONH00773"],"award-info":[{"award-number":["CONH00773"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Multistate Research Project","award":["NE1443"],"award-info":[{"award-number":["NE1443"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Virology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.coviro.2016.08.005","type":"journal-article","created":{"date-parts":[[2016,8,28]],"date-time":"2016-08-28T05:32:29Z","timestamp":1472362349000},"page":"67-74","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"special_numbering":"C","title":["Transmission and evolution of tick-borne viruses"],"prefix":"10.1016","volume":"21","author":[{"given":"Doug E","family":"Brackney","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip M","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.coviro.2016.08.005_bib0320","first-page":"157","article-title":"Tick-borne arboviral diseases","volume":"vol 2","author":"Sonenshine","year":"1993"},{"key":"10.1016\/j.coviro.2016.08.005_bib0325","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1099\/vir.0.011437-0","article-title":"Tick-borne encephalitis virus\u2014a review of an emerging zoonosis","volume":"90","author":"Mansfield","year":"2009","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0330","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1093\/trstmh\/trv050","article-title":"The global distribution of Crimean-Congo hemorrhagic fever","volume":"109","author":"Messina","year":"2015","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0335","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1146\/annurev-ento-112408-085446","article-title":"Update on Powassan virus: emergence of a North American tick-borne flavivirus","volume":"55","author":"Ebel","year":"2010","journal-title":"Annu Rev Entomol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0340","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1056\/NEJMoa1010095","article-title":"Fever with thrombocytopenia associated with a novel bunyavirus in China","volume":"364","author":"Yu","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.coviro.2016.08.005_bib0345","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1056\/NEJMoa1203378","article-title":"A new phlebovirus associated with severe febrile illness in Missouri","volume":"367","author":"McMullan","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.coviro.2016.08.005_bib0350","doi-asserted-by":"crossref","first-page":"760","DOI":"10.3201\/eid2105.150150","article-title":"Novel thogotovirus associated with febrile illness and death, United States, 2014","volume":"21","author":"Kosoy","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.coviro.2016.08.005_bib0355","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/nrmicro863","article-title":"The population genetics and evolutionary epidemiology of RNA viruses","volume":"2","author":"Moya","year":"2004","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0360","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.coviro.2012.12.003","article-title":"What can we predict about viral evolution and emergence?","volume":"3","author":"Holmes","year":"2013","journal-title":"Curr Opin Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0365","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1743-422X-11-26","article-title":"Genome characterization of Long Island tick rhabdovirus, a new virus identified in Amblyomma americanum ticks","volume":"11","author":"Tokarz","year":"2014","journal-title":"Virol J"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0370","doi-asserted-by":"crossref","first-page":"11480","DOI":"10.1128\/JVI.01858-14","article-title":"Virome analysis of Amblyomma americanum, Dermacentor variabilis, and Ixodes scapularis ticks reveals novel highly divergent vertebrate and invertebrate viruses","volume":"88","author":"Tokarz","year":"2014","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0375","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.3390\/v7092851","article-title":"Insect-specific virus discovery: significance for the arbovirus community","volume":"7","author":"Bolling","year":"2015","journal-title":"Viruses"},{"key":"10.1016\/j.coviro.2016.08.005_bib0380","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.antiviral.2013.07.006","article-title":"Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome, and genetic diversity","volume":"100","author":"Bente","year":"2013","journal-title":"Antiviral Res"},{"key":"10.1016\/j.coviro.2016.08.005_bib0385","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1099\/0022-1317-82-8-1867","article-title":"Phylogenetic relationships of flaviviruses correlate with their epidemiology, disease association and biogeography","volume":"82","author":"Gaunt","year":"2001","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0390","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1099\/vir.0.036525-0","article-title":"Molecular evolution of the insect-specific flaviviruses","volume":"93","author":"Cook","year":"2012","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0395","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.virol.2006.09.015","article-title":"Genetic characterization of tick-borne flaviviruses: new insights into evolution, pathogenetic determinants and taxonomy","volume":"361","author":"Grard","year":"2007","journal-title":"Virology"},{"key":"10.1016\/j.coviro.2016.08.005_bib0400","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1006\/bbrc.2001.5610","article-title":"Complete coding sequence of the Alkhurma virus, a tick-borne flavivirus causing severe hemorrhagic fever in humans in Saudi Arabia","volume":"287","author":"Charrel","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.coviro.2016.08.005_bib0405","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0168-1702(01)00330-6","article-title":"Nucleotide sequencing and serological evidence that the recently recognized deer tick virus is a genotype of Powassan virus","volume":"79","author":"Beasley","year":"2001","journal-title":"Virus Res"},{"key":"10.1016\/j.coviro.2016.08.005_bib0410","doi-asserted-by":"crossref","first-page":"671","DOI":"10.4269\/ajtmh.2001.65.671","article-title":"Genomic sequencing of deer tick virus and phylogeny of powassan-related viruses of North America","volume":"65","author":"Kuno","year":"2001","journal-title":"Am J Trop Med Hyg"},{"issue":"Suppl.","key":"10.1016\/j.coviro.2016.08.005_bib0415","doi-asserted-by":"crossref","first-page":"S221","DOI":"10.1017\/S0031182004005220","article-title":"Tick-borne viruses","volume":"129","author":"Labuda","year":"2004","journal-title":"Parasitology"},{"key":"10.1016\/j.coviro.2016.08.005_bib0420","doi-asserted-by":"crossref","first-page":"146","DOI":"10.4269\/ajtmh.1991.45.146","article-title":"Dissemination, replication, and trans-stadial persistence of Dugbe virus (Nairovirus, Bunyaviridae) in the tick vector Amblyomma variegatum","volume":"45","author":"Booth","year":"1991","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.coviro.2016.08.005_bib0425","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1139\/m69-252","article-title":"Localization of Powassan virus in Dermacentor andersoni ticks by immunofluorescence","volume":"15","author":"Chernesky","year":"1969","journal-title":"Can J Microbiol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0430","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1365-2915.1989.tb00498.x","article-title":"Vector capacity of Rhipicephalus appendiculatus and Amblyomma variegatum for Thogoto and Dhori viruses","volume":"3","author":"Jones","year":"1989","journal-title":"Med Vet Entomol"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0435","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jmedent\/31.1.1","article-title":"Adaptations of arboviruses to ticks","volume":"31","author":"Nuttall","year":"1994","journal-title":"J Med Entomol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0440","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0168-1702(89)90071-3","article-title":"Difference in vector competence of two species of sympatric ticks, Amblyomma variegatum and Rhipicephalus appendiculatus, for Dugbe virus (Nairovirus, Bunyaviridae)","volume":"14","author":"Steele","year":"1989","journal-title":"Virus Res"},{"key":"10.1016\/j.coviro.2016.08.005_bib0445","series-title":"Principles of Acarology","author":"Evans","year":"1992"},{"key":"10.1016\/j.coviro.2016.08.005_bib0450","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.4269\/ajtmh.1986.35.1256","article-title":"Experimental studies on the transmission cycle of Thogoto virus, a candidate orthomyxovirus, in Rhipicephalus appendiculatus","volume":"35","author":"Davies","year":"1986","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.coviro.2016.08.005_bib0455","doi-asserted-by":"crossref","first-page":"180","DOI":"10.4269\/ajtmh.1985.34.180","article-title":"Experimental studies on the replication and dissemination of Qalyub virus (Bunyaviridae: Nairovirus) in the putative tick vector, Ornithodoros (Pavlovskyella) erraticus","volume":"34","author":"Miller","year":"1985","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.coviro.2016.08.005_bib0460","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/jmedent\/15.4.307","article-title":"The epidemiology of tick-borne Crimean-Congo hemorrhagic fever in Asia, Europe, and Africa","volume":"15","author":"Hoogstraal H:","year":"1979","journal-title":"J Med Entomol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0465","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jprot.2015.07.005","article-title":"Modulation of host immunity by tick saliva","volume":"128","author":"Kotal","year":"2015","journal-title":"J Proteomics"},{"key":"10.1016\/j.coviro.2016.08.005_bib0470","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0169-4758(90)90338-5","article-title":"The role of vector saliva in transmission of arthropod-borne disease","volume":"6","author":"Titus","year":"1990","journal-title":"Parasitol Today"},{"key":"10.1016\/j.coviro.2016.08.005_bib0475","doi-asserted-by":"crossref","first-page":"7852","DOI":"10.1128\/JVI.01056-15","article-title":"Tick saliva enhances Powassan virus transmission to the host, influencing its dissemination and the course of disease","volume":"15","author":"Hermance","year":"2015","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0480","first-page":"28","article-title":"The possible role of the salivary gland substrate in ixodid ticks as an adjuvant enhancing arbovirus transmission","author":"Alekseev","year":"1991","journal-title":"Med Parazitol (Mosk)"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0485","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1126\/science.3616608","article-title":"A novel mode of arbovirus transmission involving a nonviremic host","volume":"237","author":"Jones","year":"1987","journal-title":"Science"},{"issue":"Part 7","key":"10.1016\/j.coviro.2016.08.005_bib0490","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1099\/0022-1317-70-7-1895","article-title":"Enhancement of virus transmission by tick salivary glands","volume":"70","author":"Jones","year":"1989","journal-title":"J Gen Virol"},{"issue":"Suppl.","key":"10.1016\/j.coviro.2016.08.005_bib0495","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1017\/S0031182000075818","article-title":"Persistence and transmission of tick-borne viruses: Ixodes ricinus and louping-ill virus in red grouse populations","volume":"111","author":"Hudson","year":"1995","journal-title":"Parasitology"},{"key":"10.1016\/j.coviro.2016.08.005_bib0500","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3389\/fbioe.2016.00040","article-title":"Stability of a tick-borne flavivirus in milk","volume":"4","author":"Offerdahl","year":"2016","journal-title":"Front Bioeng Biotechnol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0505","first-page":"635","article-title":"A common-source outbreak of Crimean-Congo haemorrhagic fever on a dairy farm","volume":"68","author":"Swanepoel","year":"1985","journal-title":"S Afr Med J"},{"key":"10.1016\/j.coviro.2016.08.005_bib0510","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.tmrv.2004.07.001","article-title":"Transfusion-transmitted tick-borne infections: a cornucopia of threats","volume":"18","author":"Leiby","year":"2004","journal-title":"Transfus Med Rev"},{"key":"10.1016\/j.coviro.2016.08.005_bib0515","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1099\/vir.0.054478-0","article-title":"Molecular phylogeography of tick-borne encephalitis virus in central Europe","volume":"94","author":"Weidmann","year":"2013","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0520","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1099\/vir.0.024232-0","article-title":"Molecular epidemiology of Powassan virus in North America","volume":"91","author":"Pesko","year":"2010","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0525","doi-asserted-by":"crossref","first-page":"8663","DOI":"10.1128\/JVI.01013-12","article-title":"Revisiting the clinal concept of evolution and dispersal for the tick-borne flaviviruses by using phylogenetic and biogeographic analyses","volume":"86","author":"Heinze","year":"2012","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0530","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.meegid.2012.10.011","article-title":"Clusteron structure of tick-borne encephalitis virus populations","volume":"14","author":"Kovalev","year":"2013","journal-title":"Infect Genet Evol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0535","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1073\/pnas.93.2.548","article-title":"Population dynamics of flaviviruses revealed by molecular phylogenies","volume":"93","author":"Zanotto","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.coviro.2016.08.005_bib0540","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1006\/viro.1995.1326","article-title":"An arbovirus cline across the northern hemisphere","volume":"210","author":"Zanotto","year":"1995","journal-title":"Virology"},{"issue":"Part 1","key":"10.1016\/j.coviro.2016.08.005_bib0545","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1099\/0022-1317-80-1-179","article-title":"Sequence analysis and genetic classification of tick-borne encephalitis viruses from Europe and Asia","volume":"80","author":"Ecker","year":"1999","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0550","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/jmv.2097","article-title":"Characterization of tick-borne encephalitis virus from Latvia: evidence for co-circulation of three distinct subtypes","volume":"65","author":"Lundkvist","year":"2001","journal-title":"J Med Virol"},{"issue":"Part 1","key":"10.1016\/j.coviro.2016.08.005_bib0555","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1099\/0022-1317-70-1-37","article-title":"Antigenic relationships between flaviviruses as determined by cross-neutralization tests with polyclonal antisera","volume":"70","author":"Calisher","year":"1989","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0560","doi-asserted-by":"crossref","first-page":"4307","DOI":"10.1002\/ece3.1301","article-title":"Tick-borne encephalitis virus subtypes emerged through rapid vector switches rather than gradual evolution","volume":"4","author":"Kovalev","year":"2014","journal-title":"Ecol Evol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0565","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1099\/0022-1317-82-7-1657","article-title":"Phylogeny of North American Powassan virus","volume":"82","author":"Ebel","year":"2001","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0570","doi-asserted-by":"crossref","first-page":"971","DOI":"10.4269\/ajtmh.2008.79.971","article-title":"Stable prevalence of Powassan virus in Ixodes scapularis in a northern Wisconsin focus","volume":"79","author":"Brackney","year":"2008","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0575","doi-asserted-by":"crossref","first-page":"754","DOI":"10.4269\/ajtmh.2012.12-0294","article-title":"Prevalence and genetic characterization of Powassan virus strains infecting Ixodes scapularis in Connecticut","volume":"87","author":"Anderson","year":"2012","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.coviro.2016.08.005_bib0580","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1093\/cid\/civ1005","article-title":"Emerging cases of Powassan virus encephalitis in New England: clinical presentation, imaging, and review of the literature","volume":"62","author":"Piantadosi","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.coviro.2016.08.005_bib0585","doi-asserted-by":"crossref","first-page":"e1001005","DOI":"10.1371\/journal.ppat.1001005","article-title":"Quasispecies theory and the behavior of RNA viruses","volume":"6","author":"Lauring","year":"2010","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.coviro.2016.08.005_bib0590","doi-asserted-by":"crossref","first-page":"155","DOI":"10.2217\/fmb.12.139","article-title":"Factors shaping the adaptive landscape for arboviruses: implications for the emergence of disease","volume":"8","author":"Coffey","year":"2013","journal-title":"Future Microbiol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0595","doi-asserted-by":"crossref","first-page":"e1000502","DOI":"10.1371\/journal.ppat.1000502","article-title":"RNAi targeting of West Nile virus in mosquito midguts promotes virus diversification","volume":"5","author":"Brackney","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.coviro.2016.08.005_bib0600","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.meegid.2012.01.022","article-title":"Quantification of intrahost bottlenecks of West Nile virus in Culex pipiens mosquitoes using an artificial mutant swarm","volume":"12","author":"Ciota","year":"2012","journal-title":"Infect Genet Evol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0605","doi-asserted-by":"crossref","first-page":"e1002897","DOI":"10.1371\/journal.ppat.1002897","article-title":"Vector-borne transmission imposes a severe bottleneck on an RNA virus population","volume":"8","author":"Forrester","year":"2012","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.coviro.2016.08.005_bib0610","doi-asserted-by":"crossref","first-page":"e1004874","DOI":"10.1371\/journal.ppat.1004874","article-title":"Experimental evolution of an RNA virus in wild birds: evidence for host-dependent impacts on population structure and competitive fitness","volume":"11","author":"Grubaugh","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.coviro.2016.08.005_bib0615","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.chom.2016.03.002","article-title":"Genetic drift during systemic arbovirus infection of mosquito vectors leads to decreased relative fitness during host switching","volume":"19","author":"Grubaugh","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.coviro.2016.08.005_sbref0620","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.virol.2010.03.035","article-title":"Homogeneity of Powassan virus populations in naturally infected Ixodes scapularis","volume":"402","author":"Brackney","year":"2010","journal-title":"Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0625","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1099\/vir.0.81015-0","article-title":"Genetic variation in West Nile virus from naturally infected mosquitoes and birds suggests quasispecies structure and strong purifying selection","volume":"86","author":"Jerzak","year":"2005","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2016.08.005_bib0630","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1128\/JVI.02612-14","article-title":"Modulation of flavivirus population diversity by RNA interference","volume":"89","author":"Brackney","year":"2015","journal-title":"J Virol"}],"container-title":["Current Opinion in Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879625716301018?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879625716301018?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T10:00:10Z","timestamp":1761818410000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1879625716301018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":63,"alternative-id":["S1879625716301018"],"URL":"https:\/\/doi.org\/10.1016\/j.coviro.2016.08.005","relation":{},"ISSN":["1879-6257"],"issn-type":[{"value":"1879-6257","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transmission and evolution of tick-borne viruses","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.coviro.2016.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}