{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T05:57:17Z","timestamp":1793167037537,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,22]],"date-time":"2020-05-22T00:00:00Z","timestamp":1590105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Virology"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.coviro.2020.05.003","type":"journal-article","created":{"date-parts":[[2020,6,28]],"date-time":"2020-06-28T13:28:19Z","timestamp":1593350899000},"page":"35-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Highly efficient vaccines for Bluetongue virus and a related Orbivirus based on reverse genetics"],"prefix":"10.1016","volume":"44","author":[{"given":"Polly","family":"Roy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.coviro.2020.05.003_bib0005","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.chom.2007.03.003","article-title":"A plasmid-based reverse genetics system for animal double-stranded RNA viruses","volume":"1","author":"Kobayashi","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.coviro.2020.05.003_sbref0010","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1128\/JVI.01819-06","article-title":"Recovery of infectious bluetongue virus from RNA","volume":"81","author":"Boyce","year":"2007","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0015","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nrmicro1090","article-title":"Climate change and the recent emergence of bluetongue in Europe","volume":"3","author":"Purse","year":"2005","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0020","doi-asserted-by":"crossref","first-page":"539","DOI":"10.3201\/eid1404.071441","article-title":"Bluetongue epidemiology in the European Union","volume":"14","author":"Saegerman","year":"2008","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.coviro.2020.05.003_bib0025","series-title":"Fields Virology","article-title":"Orbiviruses","author":"Roy","year":"2013"},{"key":"10.1016\/j.coviro.2020.05.003_bib0030","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.coviro.2017.05.003","article-title":"Bluetongue virus structure and assembly","volume":"24","author":"Roy","year":"2017","journal-title":"Curr Opin Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0035","doi-asserted-by":"crossref","first-page":"9832","DOI":"10.1128\/JVI.73.12.9832-9842.1999","article-title":"Expression and functional characterization of bluetongue virus VP2 protein: role in cell entry","volume":"73","author":"Hassan","year":"1999","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0040","doi-asserted-by":"crossref","first-page":"8356","DOI":"10.1128\/JVI.75.18.8356-8367.2001","article-title":"Expression and functional characterization of bluetongue virus VP5 protein: role in cellular permeabilization","volume":"75","author":"Hassan","year":"2001","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0045","doi-asserted-by":"crossref","first-page":"6292","DOI":"10.1073\/pnas.0913403107","article-title":"Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins","volume":"107","author":"Zhang","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.coviro.2020.05.003_bib0050","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1099\/vir.0.82456-0","article-title":"Analysis and phylogenetic comparisons of full-length VP2 genes of the 24 bluetongue virus serotypes","volume":"88","author":"Maan","year":"2007","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026147","article-title":"Complete genome characterisation of a novel 26th bluetongue virus serotype from Kuwait","volume":"6","author":"Maan","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.coviro.2020.05.003_bib0060","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/0042-6822(87)90327-8","article-title":"Uncoating of parental bluetongue virus to core and subcore particles in infected L cells","volume":"157","author":"Huismans","year":"1987","journal-title":"Virology"},{"key":"10.1016\/j.coviro.2020.05.003_bib0065","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/26694","article-title":"The atomic structure of the bluetongue virus core","volume":"395","author":"Grimes","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.coviro.2020.05.003_bib0070","doi-asserted-by":"crossref","first-page":"8059","DOI":"10.1128\/JVI.78.15.8059-8067.2004","article-title":"Interactions between the inner and outer capsids of bluetongue virus","volume":"78","author":"Nason","year":"2004","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0075","first-page":"185","article-title":"Studies on the in vitro and the in vivo transcription of the bluetongue virus genome","volume":"39","author":"Verwoerd","year":"1972","journal-title":"Onderstepoort J Vet Res"},{"key":"10.1016\/j.coviro.2020.05.003_bib0080","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0042-6822(73)90400-5","article-title":"Control of transcription during the expression of the bluetongue virus genome","volume":"52","author":"Huismans","year":"1973","journal-title":"Virology"},{"key":"10.1016\/j.coviro.2020.05.003_bib0085","doi-asserted-by":"crossref","first-page":"8339","DOI":"10.1128\/JVI.00808-08","article-title":"Development of reverse genetics systems for bluetongue virus: recovery of infectious virus from synthetic RNA transcripts","volume":"82","author":"Boyce","year":"2008","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0090","doi-asserted-by":"crossref","first-page":"8842","DOI":"10.1128\/JVI.00465-09","article-title":"Bluetongue virus VP6 acts early in the replication cycle and can form the basis of chimeric virus formation","volume":"83","author":"Matsuo","year":"2009","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_sbref0095","doi-asserted-by":"crossref","first-page":"10213","DOI":"10.1128\/JVI.05412-11","article-title":"Generation of replication-defective virus-based vaccines that confer full protection in sheep against virulent bluetongue virus challenge","volume":"85","author":"Matsuo","year":"2011","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0100","doi-asserted-by":"crossref","first-page":"9856","DOI":"10.1128\/JVI.01514-13","article-title":"Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep","volume":"87","author":"Celma","year":"2013","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0105","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.01892-16","article-title":"Replication-deficient particles: new insights into the next generation of bluetongue virus vaccines","volume":"91","author":"Celma","year":"2017","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0110","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1099\/vir.0.065615-0","article-title":"Bluetongue virus without NS3\/NS3a expression is not virulent and protects against virulent bluetongue virus challenge","volume":"95","author":"Feenstra","year":"2014","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0115","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.vaccine.2014.12.003","article-title":"Application of bluetongue disabled infectious single animal (DISA) vaccine for different serotypes by VP2 exchange or incorporation of chimeric VP2","volume":"33","author":"Feenstra","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.coviro.2020.05.003_bib0120","doi-asserted-by":"crossref","first-page":"7405","DOI":"10.1128\/JVI.00548-16","article-title":"Assembly of replication-incompetent African horse sickness virus particles: rational design of vaccines for all serotypes","volume":"90","author":"Lulla","year":"2016","journal-title":"J Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0125","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1099\/vir.0.055905-0","article-title":"Recovery of African horse sickness virus from synthetic RNA","volume":"94","author":"Kaname","year":"2013","journal-title":"J Gen Virol"},{"key":"10.1016\/j.coviro.2020.05.003_bib0130","doi-asserted-by":"crossref","first-page":"3386","DOI":"10.1016\/j.febslet.2010.06.030","article-title":"A reverse genetics system of African horse sickness virus reveals existence of primary replication","volume":"584","author":"Matsuo","year":"2010","journal-title":"FEBS Lett"},{"key":"10.1016\/j.coviro.2020.05.003_sbref0135","doi-asserted-by":"crossref","first-page":"4262","DOI":"10.1016\/j.vaccine.2017.06.023","article-title":"Protective efficacy of multivalent replication-abortive vaccine strains in horses against African horse sickness virus challenge","volume":"35","author":"Lulla","year":"2017","journal-title":"Vaccine"}],"container-title":["Current Opinion in Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879625720300249?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1879625720300249?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T10:05:31Z","timestamp":1761818731000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1879625720300249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":27,"alternative-id":["S1879625720300249"],"URL":"https:\/\/doi.org\/10.1016\/j.coviro.2020.05.003","relation":{},"ISSN":["1879-6257"],"issn-type":[{"value":"1879-6257","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Highly efficient vaccines for Bluetongue virus and a related Orbivirus based on reverse genetics","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.coviro.2020.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}