{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T16:58:25Z","timestamp":1769878705819,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Institute of Cardiology, Warsaw","award":["2.7\/III\/14"],"award-info":[{"award-number":["2.7\/III\/14"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Problems in Cardiology"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.cpcardiol.2019.100508","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T08:50:26Z","timestamp":1575276626000},"page":"100508","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Differences in Symptomatology and Clinical Course of Acute Coronary Syndromes in Women \u226445 Years of Age Compared to Older Women"],"prefix":"10.1016","volume":"46","author":[{"given":"Maciej","family":"B\u0119\u0107kowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilona","family":"Kowalik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Jaworski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafa\u0142","family":"D\u0105browski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Gierlotka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariusz","family":"G\u0105sior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lech","family":"Polo\u0144ski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Zdrojewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaros\u0142aw","family":"Karwowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Drygas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Szwed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cpcardiol.2019.100508_bib0001","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1089\/jwh.2013.4507","article-title":"Do younger women fare worse? Sex differences in acute myocardial infarction hospitalization and early mortality rates over ten years","volume":"23","author":"Izadnegahdar","year":"2014","journal-title":"J Womens Health (Larchmt)"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0002","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1001\/2012.jama.11348","article-title":"Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction","volume":"308","author":"Puymirat","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0003","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.amjmed.2017.05.028","article-title":"Sex differences in the management and 5-year outcome of young patients (<55 Years) with acute coronary syndromes","volume":"130","author":"Sabbag","year":"2017","journal-title":"Am J Med"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0004","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ijcard.2016.11.148","article-title":"Clinical characteristics and prognosis of acute coronary syndrome in young women and men: a systematic review and meta-analysis of prospective studies","volume":"228","author":"Ma","year":"2017","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0005","first-page":"629","article-title":"Sex-related differences in outcomes among men and women under 55 years of age with acute coronary syndrome undergoing percutaneous coronary intervention: results from the PROMETHEUS study","volume":"89","author":"Chandrasekhar","year":"2017","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0006","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1089\/jwh.2014.5011","article-title":"Accessibility to reperfusion therapy among women with acute myocardial infarction: impact on hospital mortality","volume":"24","author":"de-Miguel-Balsa","year":"2015","journal-title":"J Womens Health (Larchmt)"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0007","first-page":"334","article-title":"Is the difference in outcome between men and women treated by primary percutaneous coronary intervention age dependent? Gender difference in STEMI stratified on age","volume":"2","author":"Otten","year":"2013","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0008","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1136\/hrt.2007.138537","article-title":"Sex-related differences in the presentation, treatment and outcomes among patients with acute coronary syndromes: the Global Registry of Acute Coronary Events","volume":"95","author":"Dey","year":"2009","journal-title":"Heart"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0009","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1093\/eurheartj\/ehi719","article-title":"Impact of age and gender on in-hospital and late mortality after acute myocardial infarction: increased early risk in younger women: results from the French nation-wide USIC registries","volume":"27","author":"Simon","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0010","first-page":"610","article-title":"Editor's Choice-Sex differences in young patients with acute myocardial infarction: a VIRGO study analysis","volume":"6","author":"Bucholz","year":"2017","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0011","first-page":"1863","article-title":"Sex differences in acute coronary syndrome symptom presentation in young patients","volume":"173","author":"Khan","year":"2013","journal-title":"JAMA Intern Med"},{"issue":"Suppl 1","key":"10.1016\/j.cpcardiol.2019.100508_bib0012","first-page":"13","article-title":"Project, logistics and methodology of the National Registry of Acute Coronary Syndrome (PL-ACS)","volume":"62","author":"Gierlotka","year":"2005","journal-title":"Kardiol Pol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0013","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1007\/s00380-016-0806-1","article-title":"Gender differences in plaque characteristics of culprit lesions in patients with ST elevation myocardial infarction","volume":"31","author":"Ann","year":"2016","journal-title":"Heart Vessels"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0014","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.ahj.2010.12.022","article-title":"Women have less severe and extensive coronary atherosclerosis in fatal cases of ischemic heart disease: an autopsy study","volume":"161","author":"Smilowitz","year":"2011","journal-title":"Am Heart J"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0015","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1161\/CIRCOUTCOMES.114.001612","article-title":"Symptom recognition and healthcare experiences of young women with acute myocardial infarction","volume":"8","author":"Lichtman","year":"2015","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0016","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1136\/pgmj.2004.027532","article-title":"Myocardial infarction in young adults","volume":"81","author":"Egred","year":"2005","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0017","first-page":"814","article-title":"Nonatherosclerotic coronary artery disease in young women","volume":"30","author":"Saw","year":"2014","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0018","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/jama.2012.199","article-title":"Association of age and sex with myocardial infarction symptom presentation and in-hospital mortality","volume":"307","author":"Canto","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0019","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1161\/CIRCULATIONAHA.117.031650","article-title":"Sex differences in the presentation and perception of symptoms among young patients with myocardial infarction: evidence from the VIRGO study (variation in recovery: role of gender on outcomes of young AMI Pptients)","volume":"137","author":"Lichtman","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0020","doi-asserted-by":"crossref","first-page":"6546","DOI":"10.1016\/0735-1097(95)00254-2","article-title":"Myocardial infarction in young adults: angiographic characterization, risk factors and prognosis (Coronary Artery Surgery Study Registry)","volume":"26","author":"Zimmerman","year":"1995","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0021","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ijcard.2018.03.135","article-title":"Risk factors predisposing to acute coronary syndromes in young women \u226445 years of age","volume":"264","author":"B\u0119\u0107kowski","year":"2018","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0022","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s40292-017-0183-6","article-title":"Long-term outcome of acute coronary syndromes in young patients","volume":"24","author":"Tini","year":"2017","journal-title":"High Blood Press Cardiovasc Prev"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0023","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/s00392-015-0827-2","article-title":"Acute coronary syndrome in young women under 55 years of age: clinical characteristics, treatment, and outcomes","volume":"104","author":"Davis","year":"2015","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0024","article-title":"Factors affecting early mortality and 1-year outcomes in young women with ST-segment-elevation myocardial infarction aged less than or equal to 45 years","author":"B\u0119\u0107kowski","year":"2019","journal-title":"Curr Probl Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0025","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1177\/2047487313494580","article-title":"Age and sex inequalities in the prescription of evidence-based pharmacological therapy following an acute coronary syndrome in Portugal: the EURHOBOP study","volume":"21","author":"Pereira","year":"2014","journal-title":"Eur J Prev Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0026","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.ijcard.2015.09.012","article-title":"Short and long-term survival after primary percutaneous coronary intervention in young patients with ST-elevation myocardial infarction","volume":"203","author":"Waziri","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0027","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/clc.20718","article-title":"Acute ST-elevation myocardial infarction in young patients: 15 years of experience in a single center","volume":"33","author":"Chua","year":"2010","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0028","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1378\/chest.126.2.461","article-title":"Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global Registry of Acute Coronary Events","volume":"126","author":"Brieger","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0029","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.amjcard.2003.10.006","article-title":"Six-month outcomes in a multinational registry of patients hospitalized with an acute coronary syndrome (the Global Registry of Acute Coronary Events [GRACE])","volume":"93","author":"Goldberg","year":"2004","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cpcardiol.2019.100508_bib0030","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ijcard.2010.07.008","article-title":"A comparison of ST elevation versus non-ST elevation myocardial infarction outcomes in a large registry database: are non-ST myocardial infarctions associated with worse long-term prognoses?","volume":"152","author":"Polonski","year":"2011","journal-title":"Int J Cardiol"}],"container-title":["Current Problems in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146280619301811?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146280619301811?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T02:17:40Z","timestamp":1758939460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0146280619301811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S0146280619301811"],"URL":"https:\/\/doi.org\/10.1016\/j.cpcardiol.2019.100508","relation":{},"ISSN":["0146-2806"],"issn-type":[{"value":"0146-2806","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differences in Symptomatology and Clinical Course of Acute Coronary Syndromes in Women \u226445 Years of Age Compared to Older Women","name":"articletitle","label":"Article Title"},{"value":"Current Problems in Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cpcardiol.2019.100508","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"name":"copyright","label":"Copyright"}],"article-number":"100508"}}