{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T17:40:12Z","timestamp":1756834812402,"version":"3.44.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UM1TR004528"],"award-info":[{"award-number":["UM1TR004528"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Problems in Cardiology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.cpcardiol.2025.103128","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T06:57:52Z","timestamp":1752821872000},"page":"103128","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Heart failure with microvascular dysfunction: Insights from a propensity-matched analysis of diabetic retinopathy in heart failure with reduced ejection fraction"],"prefix":"10.1016","volume":"50","author":[{"suffix":"Jr","given":"Silvio Nunes","family":"Augusto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rochell","family":"Issa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Kaelber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8335-735X","authenticated-orcid":false,"given":"W.H. Wilson","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cpcardiol.2025.103128_bib0001","doi-asserted-by":"crossref","first-page":"829","DOI":"10.3390\/jcm13030829","article-title":"The eye as the window to the heart: optical coherence tomography angiography biomarkers as indicators of cardiovascular disease","volume":"13","author":"Kellner","year":"2024","journal-title":"J Clin Med"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0002","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.pcad.2024.10.011","article-title":"Optical coherence tomography angiography in cardiovascular disease","volume":"87","author":"Runsewe","year":"2024","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0003","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.amepre.2021.05.018","article-title":"Awareness of diabetic retinopathy: insight from the national health and nutrition examination survey","volume":"61","author":"Nwanyanwu","year":"2021","journal-title":"Am J Prev Med"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0004","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1001\/jama.293.1.63","article-title":"Retinopathy and risk of congestive heart failure","volume":"293","author":"Wong","year":"2005","journal-title":"Jama"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0005","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1016\/j.jacc.2007.11.076","article-title":"Diabetic retinopathy and risk of heart failure","volume":"51","author":"Cheung","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0006","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The strengthening the reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0007","article-title":"Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy","volume":"13","author":"Yang","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0008","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1016\/j.jacc.2008.09.055","article-title":"The pathologic continuum of diabetic vascular disease","volume":"53","author":"Orasanu","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0009","doi-asserted-by":"crossref","first-page":"150","DOI":"10.2337\/dc17-0755","article-title":"The prognostic significance of diabetes and microvascular complications in patients with heart failure with preserved ejection fraction","volume":"41","author":"Sandesara","year":"2018","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0010","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.ahj.2008.10.019","article-title":"Adverse association between diabetic retinopathy and cardiac structure and function","volume":"157","author":"Aguilar","year":"2009","journal-title":"Am Heart J"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0011","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.ophtha.2020.12.019","article-title":"Severity of diabetic retinopathy and the risk of future cerebrovascular disease, cardiovascular disease, and all-cause mortality","volume":"128","author":"Modjtahedi","year":"2021","journal-title":"Ophthalmology"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0012","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s12933-023-01821-8","article-title":"Impact of individual microvascular disease on the risks of macrovascular complications in type 2 diabetes: a nationwide population-based cohort study","volume":"22","author":"Yen","year":"2023","journal-title":"Cardiovasc Diabetol"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0013","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1002\/ejhf.3474","article-title":"Cardio-ocular syndrome: retinal microvascular changes in acutely decompensated heart failure","volume":"26","author":"Abdin","year":"2024","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0014","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/ejhf.1537","article-title":"Retinal microvascular dysfunction in patients with coronary artery disease with and without heart failure: a continuum?","volume":"21","author":"Barthelmes","year":"2019","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0015","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s00395-011-0237-1","article-title":"The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: an update","volume":"107","author":"Zhang","year":"2012","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdiacomp.2020.107613","article-title":"Molecular complexities underlying the vascular complications of diabetes mellitus - a comprehensive review","volume":"34","author":"Paul","year":"2020","journal-title":"J Diabetes Complicat"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0017","doi-asserted-by":"crossref","first-page":"6052","DOI":"10.1038\/s41598-021-85606-7","article-title":"Type 2 diabetes progression differently affects endothelial function and vascular contractility in the aorta and the pulmonary artery","volume":"11","author":"Melo","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0018","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/j.jacc.2004.07.060","article-title":"New aspects in the pathogenesis of diabetic atherothrombosis","volume":"44","author":"Moreno","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0019","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2174\/092986709787002853","article-title":"Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets","volume":"16","author":"Potenza","year":"2009","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0020","doi-asserted-by":"crossref","first-page":"883","DOI":"10.2337\/dc08-2005","article-title":"Structural and functional cardiac abnormalities in adolescent girls with poorly controlled type 2 diabetes","volume":"32","author":"Whalley","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0021","article-title":"Association between severity of diabetic retinopathy and cardiac function in patients with type 2 diabetes","volume":"2023","author":"Chen","year":"2023","journal-title":"J Diabetes Res"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0022","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1016\/j.numecd.2022.04.020","article-title":"Impact of diabetic retinopathy on prognosis of patients with heart failure with preserved ejection fraction","volume":"32","author":"Yang","year":"2022","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0023","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.atherosclerosis.2019.10.017","article-title":"Body mass index and peripheral artery disease","volume":"292","author":"Heffron","year":"2020","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0024","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1161\/STROKEAHA.115.008940","article-title":"Obesity increases risk of ischemic stroke in young adults","volume":"46","author":"Mitchell","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.cpcardiol.2025.103128_bib0025","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1681\/ASN.2020081156","article-title":"BP in young adults with CKD and associations with cardiovascular events and decline in kidney function","volume":"32","author":"Kula","year":"2021","journal-title":"J Am Soc Nephrol"}],"container-title":["Current Problems in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146280625001483?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146280625001483?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T17:05:03Z","timestamp":1756832703000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0146280625001483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0146280625001483"],"URL":"https:\/\/doi.org\/10.1016\/j.cpcardiol.2025.103128","relation":{},"ISSN":["0146-2806"],"issn-type":[{"type":"print","value":"0146-2806"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Heart failure with microvascular dysfunction: Insights from a propensity-matched analysis of diabetic retinopathy in heart failure with reduced ejection fraction","name":"articletitle","label":"Article Title"},{"value":"Current Problems in Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cpcardiol.2025.103128","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"103128"}}