{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:30:20Z","timestamp":1793413820854,"version":"4.5.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Problems in Cardiology"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.cpcardiol.2026.103272","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T07:39:14Z","timestamp":1768894754000},"page":"103272","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Urinary sodium-guided diuretic therapy in acute decompensated heart failure: A grade assessed systematic review and meta-analysis with trial sequential analysis"],"prefix":"10.1016","volume":"51","author":[{"given":"Ali Saad","family":"Al-Shammari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadeeja Ali","family":"Hamzah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahyar","family":"Masanabadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Asif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehak","family":"Budhiraja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimra","family":"Shafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belal Mohamed","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousif Hameed","family":"Kurmasha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammedsadeq A.","family":"Shweliya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasar","family":"Sattar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.cpcardiol.2026.103272_bib0001","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1161\/CIRCULATIONAHA.119.045409","article-title":"Altered hemodynamics and end-organ damage in heart failure: impact on the lung and kidney","volume":"142","author":"Verbrugge","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.cpcardiol.2026.103272_bib0002","article-title":"Temporal trends in acute decompensated heart failure outcomes: a single-center 11-year retrospective analysis","volume":"22","author":"Marcus","year":"2024","journal-title":"Int J Cardiol Cardiovasc Risk Prev"},{"issue":"15","key":"10.1016\/j.cpcardiol.2026.103272_bib0003","doi-asserted-by":"crossref","DOI":"10.3390\/jcm13154470","article-title":"Diuretic treatment in heart failure: a practical guide for clinicians","volume":"13","author":"Wu","year":"2024","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0004","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s11936-025-01125-y","article-title":"Evolving decongestion strategies in the management of acute heart failure","volume":"27","author":"George","year":"2025","journal-title":"Curr Treat Options Cardiovasc Med"},{"issue":"17","key":"10.1016\/j.cpcardiol.2026.103272_bib0005","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.123.030044","article-title":"Spot urinary sodium as a biomarker of diuretic response in acute heart failure","volume":"12","author":"Oliva-Damaso","year":"2023","journal-title":"JAHA"},{"issue":"36","key":"10.1016\/j.cpcardiol.2026.103272_bib0006","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.cpcardiol.2026.103272_bib0007","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/ejhf.2385","article-title":"Natriuresis-guided therapy in acute heart failure: rationale and design of the Pragmatic Urinary sodium-based treatment algoritHm in Acute Heart Failure (PUSH-AHF) trial","volume":"24","author":"Ter Maaten","year":"2022","journal-title":"Eur J Heart Fail"},{"issue":"10","key":"10.1016\/j.cpcardiol.2026.103272_bib0008","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1002\/ejhf.3429","article-title":"Nurse-led diuretic titration via a point-of-care urinary sodium sensor in patients with acute decompensated heart failure (EASY-HF): a single-centre, randomized, open-label study","volume":"26","author":"Meekers","year":"2024","journal-title":"Eur J Heart Fail"},{"issue":"12","key":"10.1016\/j.cpcardiol.2026.103272_bib0009","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1016\/j.cardfail.2023.07.012","article-title":"Urinary sodium-guided intravenous diuretic therapy in acute heart failure: transitioning from art to science?","volume":"29","author":"Pellegrino","year":"2023","journal-title":"J Card Fail"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0010","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s13643-021-01626-4","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"10","author":"Page","year":"2021","journal-title":"Syst Rev"},{"key":"10.1016\/j.cpcardiol.2026.103272_bib0011","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.cpcardiol.2026.103272_bib0012","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"issue":"7650","key":"10.1016\/j.cpcardiol.2026.103272_bib0013","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0014","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1093\/ehjqcco\/qcae028","article-title":"Spot urinary sodium-guided titration of intravenous diuretic therapy in acute heart failure: a pilot randomized controlled trial","volume":"11","author":"Khorramshahi Bayat","year":"2025","journal-title":"Eur Heart J Qual Care Clin Outcomes"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0015","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.123.011105","article-title":"Protocolized natriuresis-guided decongestion improves diuretic response: the multicenter ENACT-HF study","volume":"17","author":"Dauw","year":"2024","journal-title":"Circ Heart Fail"},{"issue":"8","key":"10.1016\/j.cpcardiol.2026.103272_bib0016","article-title":"Early versus delayed diuretic administration and urine-guided strategies in acute decompensated heart failure: a systematic review of clinical outcomes","volume":"17","author":"Muzammil","year":"2025","journal-title":"Cureus"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0017","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1159\/000546520","article-title":"Systematic review on the management of diuretic resistance in acute heart failure across the spectrum of kidney disease","volume":"15","author":"Marques","year":"2025","journal-title":"Cardiorenal Med"},{"issue":"18","key":"10.1016\/j.cpcardiol.2026.103272_bib0018","first-page":"e895","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: a report of the american college of cardiology\/american heart association joint committee on clinical practice guidelines","volume":"145","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0019","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/ejhf.2333","volume":"24","author":"McDonagh","year":"2022","journal-title":"Eur J Heart Fail"},{"issue":"2","key":"10.1016\/j.cpcardiol.2026.103272_bib0020","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/ejhf.1369","article-title":"The use of diuretics in heart failure with congestion - a position statement from the Heart Failure Association of the European Society of Cardiology","volume":"21","author":"Mullens","year":"2019","journal-title":"Eur J Heart Fail"},{"issue":"15","key":"10.1016\/j.cpcardiol.2026.103272_bib0021","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1016\/j.jacc.2019.08.001","article-title":"2019 ACC expert consensus decision pathway on risk assessment, management, and clinical trajectory of patients hospitalized with heart failure: a report of the american college of cardiology solution set oversight committee","volume":"74","author":"Hollenberg","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"8","key":"10.1016\/j.cpcardiol.2026.103272_bib0022","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1002\/ejhf.1753","article-title":"Clinical importance of urinary sodium excretion in acute heart failure","volume":"22","author":"Damman","year":"2020","journal-title":"Eur J Heart Fail"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0023","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.115.002370","article-title":"Rapid and highly accurate prediction of poor loop diuretic natriuretic response in patients with heart failure","volume":"9","author":"Testani","year":"2016","journal-title":"Circ Heart Fail"},{"issue":"4","key":"10.1016\/j.cpcardiol.2026.103272_bib0024","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1161\/CIRCHEARTFAILURE.114.001957","volume":"8","author":"Lala","year":"2015","journal-title":"Circ Heart Fail"},{"issue":"43","key":"10.1016\/j.cpcardiol.2026.103272_bib0025","doi-asserted-by":"crossref","first-page":"4468","DOI":"10.1093\/eurheartj\/ehab620","article-title":"Compensatory post-diuretic renal sodium reabsorption is not a dominant mechanism of diuretic resistance in acute heart failure","volume":"42","author":"Cox","year":"2021","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.cpcardiol.2026.103272_bib0026","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.jacc.2020.12.022","article-title":"Natriuretic equation to predict loop diuretic response in patients with heart failure","volume":"77","author":"Rao","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"10.1016\/j.cpcardiol.2026.103272_bib0027","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1002\/ehf2.14801","article-title":"External validation of the natriuretic response prediction equation to discriminate diuretic response in heart failure","volume":"12","author":"Ram\u00edrez-S\u00e1nchez","year":"2025","journal-title":"ESC Heart Fail"},{"issue":"6","key":"10.1016\/j.cpcardiol.2026.103272_bib0028","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1007\/s10741-024-10424-8","article-title":"The utility of urine sodium\u2013guided diuresis during acute decompensated heart failure","volume":"29","author":"Siddiqi","year":"2024","journal-title":"Heart Fail Rev"}],"container-title":["Current Problems in Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146280626000149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0146280626000149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:06:21Z","timestamp":1785416781000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0146280626000149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0146280626000149"],"URL":"https:\/\/doi.org\/10.1016\/j.cpcardiol.2026.103272","relation":{},"ISSN":["0146-2806"],"issn-type":[{"value":"0146-2806","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urinary sodium-guided diuretic therapy in acute decompensated heart failure: A grade assessed systematic review and meta-analysis with trial sequential analysis","name":"articletitle","label":"Article Title"},{"value":"Current Problems in Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cpcardiol.2026.103272","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103272"}}