{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:27:03Z","timestamp":1792639623939,"version":"4.5.0"},"reference-count":117,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Podiatric Medicine and Surgery"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.cpm.2009.08.002","type":"journal-article","created":{"date-parts":[[2009,9,23]],"date-time":"2009-09-23T10:46:05Z","timestamp":1253702765000},"page":"619-631","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["An Overview of Negative Pressure Wound Therapy for the Lower Extremity"],"prefix":"10.1016","volume":"26","author":[{"given":"Claire M.","family":"Capobianco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Zgonis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1054\/bjps.2001.3547","article-title":"Topical negative pressure for treating chronic wounds: a systematic review","volume":"54","author":"Evans","year":"2001","journal-title":"Br J Plast Surg"},{"issue":"Suppl1","key":"10.1016\/j.cpm.2009.08.002_bib2","doi-asserted-by":"crossref","first-page":"S119","DOI":"10.1002\/dmrr.825","article-title":"A systematic review of the effectiveness of interventions to enhance the healing of chronic ulcers of the foot in diabetes","volume":"24","author":"Hinchliffe","year":"2008","journal-title":"Diabetes Metab Res Rev"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib3","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001898.pub2","article-title":"Topical negative pressure for treating chronic wounds","author":"Ubbink","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib4","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/bjs.6238","article-title":"A systematic review of topical negative pressure therapy for acute and chronic wounds","volume":"95","author":"Ubbink","year":"2008","journal-title":"Br J Surg"},{"key":"10.1016\/j.cpm.2009.08.002_bib5","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1002\/bjs.6238","article-title":"A systematic review of topical negative pressure therapy for acute and chronic wounds","volume":"95","author":"Vig","year":"2008","journal-title":"Br J Surg"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib6","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jpedsurg.2004.09.016","article-title":"Wound management with vacuum-assisted closure: experience in 51 pediatric patients","volume":"40","author":"Caniano","year":"2005","journal-title":"J Pediatr Surg"},{"issue":"Suppl 2","key":"10.1016\/j.cpm.2009.08.002_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1742-481X.2008.00467.x","article-title":"The safety of negative pressure wound therapy using vacuum-assisted closure in diabetic foot ulcers treated in the outpatient setting","volume":"5","author":"Fife","year":"2008","journal-title":"Int Wound J"},{"issue":"Suppl 2","key":"10.1016\/j.cpm.2009.08.002_bib8","first-page":"iii","article-title":"V.A.C. therapy in home care","volume":"5","author":"Sibbald","year":"2008","journal-title":"Int Wound J"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib9","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.amjsurg.2007.06.023","article-title":"Resource utilization and economic costs of care based on a randomized trial of vacuum-assisted closure therapy in the treatment of diabetic foot wounds","volume":"195","author":"Apelqvist","year":"2008","journal-title":"Am J Surg"},{"issue":"9498","key":"10.1016\/j.cpm.2009.08.002_bib10","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1016\/S0140-6736(05)67695-7","article-title":"Negative pressure wound therapy after partial diabetic foot amputation: a multicentre, randomised controlled trial","volume":"366","author":"Armstrong","year":"2005","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib11","doi-asserted-by":"crossref","first-page":"631","DOI":"10.2337\/dc07-2196","article-title":"Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial","volume":"31","author":"Blume","year":"2008","journal-title":"Diabetes Care"},{"issue":"12","key":"10.1016\/j.cpm.2009.08.002_bib12","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/01.ASW.0000323589.27605.71","article-title":"An evidence-based model comparing the cost-effectiveness of platelet-rich plasma gel to alternative therapies for patients with nonhealing diabetic foot ulcers","volume":"21","author":"Dougherty","year":"2008","journal-title":"Adv Skin Wound Care"},{"issue":"Suppl 1","key":"10.1016\/j.cpm.2009.08.002_bib13","doi-asserted-by":"crossref","first-page":"S76","DOI":"10.1002\/dmrr.852","article-title":"The value of debridement and vacuum-assisted closure (V.A.C.) therapy in diabetic foot ulcers","volume":"24","author":"Eneroth","year":"2008","journal-title":"Diabetes Metab Res Rev"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib14","doi-asserted-by":"crossref","first-page":"71","DOI":"10.12968\/jowc.2008.17.2.28181","article-title":"An economic evaluation of VAC therapy compared with wound dressings in the treatment of diabetic foot ulcers","volume":"17","author":"Flack","year":"2008","journal-title":"J\u00a0Wound Care"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib15","doi-asserted-by":"crossref","first-page":"351","DOI":"10.7547\/0970351","article-title":"Negative-pressure wound therapy and diabetic foot amputations: a retrospective study of payer claims data","volume":"97","author":"Frykberg","year":"2007","journal-title":"J Am Podiatr Med Assoc"},{"issue":"10","key":"10.1016\/j.cpm.2009.08.002_bib16","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.2337\/dc08-0890","article-title":"Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial: response to Blume et al","volume":"31","author":"Hemkens","year":"2008","journal-title":"Diabetes Care"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.2337\/dc07-1300","article-title":"Prediction of healing for postoperative diabetic foot wounds based on early wound area progression","volume":"31","author":"Lavery","year":"2008","journal-title":"Diabetes Care"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib18","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1742-481X.2007.00317.x","article-title":"A comparison of diabetic foot ulcer outcomes using negative pressure wound therapy versus historical standard of care","volume":"4","author":"Lavery","year":"2007","journal-title":"Int Wound J"},{"issue":"9512","key":"10.1016\/j.cpm.2009.08.002_bib19","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0140-6736(06)68294-9","article-title":"Negative pressure therapy in diabetic foot wounds","volume":"367","author":"Maegele","year":"2006","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib20","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s11892-006-0077-9","article-title":"Negative pressure wound therapy: evidence-based treatment for complex diabetic foot wounds","volume":"6","author":"Suess","year":"2006","journal-title":"Curr Diab Rep"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib21","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1440-1584.2007.00908.x","article-title":"Treatment of long-standing, poor-healing diabetic foot ulcers with topical negative pressure in the Torres Strait","volume":"15","author":"Tan","year":"2007","journal-title":"Aust J Rural Health"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib22","doi-asserted-by":"crossref","first-page":"164","DOI":"10.7547\/0980164","article-title":"Negative-pressure wound therapy and diabetic foot amputations: a retrospective study of Payer Claims Data","volume":"98","author":"Udell","year":"2008","journal-title":"J Am Podiatr Med Assoc"},{"issue":"9","key":"10.1016\/j.cpm.2009.08.002_bib23","first-page":"49","article-title":"Negative pressure wound therapy combined with acoustic pressure wound therapy for infected post surgery wounds: a case series","volume":"54","author":"Howell-Taylor","year":"2008","journal-title":"Ostomy Wound Manage"},{"issue":"414","key":"10.1016\/j.cpm.2009.08.002_bib24","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/01.blo.0000084400.53464.02","article-title":"Negative pressure dressings as an alternative technique for the treatment of infected wounds","author":"Wongworawat","year":"2003","journal-title":"Clin Orthop Relat Res"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib25","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1097\/01.ASW.0000305452.79434.d9","article-title":"Cost-effectiveness of negative pressure wound therapy for postsurgical patients in long-term acute care","volume":"22","author":"de Leon","year":"2009","journal-title":"Adv Skin Wound Care"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib26","doi-asserted-by":"crossref","first-page":"410","DOI":"10.7547\/0970410","article-title":"Negative-pressure wound therapy and external fixation for infection and hematoma after hallux abducto valgus surgery","volume":"97","author":"Ferdinando","year":"2007","journal-title":"J Am Podiatr Med Assoc"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib27","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1097\/00000637-199805000-00001","article-title":"Negative-pressure dressings as a bolster for skin grafts","volume":"40","author":"Blackburn","year":"1998","journal-title":"Ann Plast Surg"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib28","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1097\/01.sap.0000245121.32831.47","article-title":"Efficacy of negative pressure therapy to enhance take of 1-stage allodermis and a split-thickness graft","volume":"58","author":"Kim","year":"2007","journal-title":"Ann Plast Surg"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib29","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1159\/000112937","article-title":"Vacuum assisted closure device improves the take of mesh grafts in chronic leg ulcer patients","volume":"216","author":"Korber","year":"2008","journal-title":"Dermatology"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib30","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1097\/01.PRS.0000133168.57199.E1","article-title":"A prospective, blinded, randomized, controlled clinical trial of topical negative pressure use in skin grafting","volume":"114","author":"Moisidis","year":"2004","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib31","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1097\/BCR.0b013e31817db8b6","article-title":"Facilitating residual wound closure after partial graft loss with vacuum assisted closure therapy","volume":"29","author":"Poulakidas","year":"2008","journal-title":"J Burn Care Res"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib32","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1524-475X.2007.00267.x","article-title":"Acute complex traumas of the lower limbs: a modern reconstructive approach with negative pressure therapy","volume":"15","author":"Bollero","year":"2007","journal-title":"Wound Repair Regen"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib33","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1097\/01.prs.0000305536.09242.a6","article-title":"Routine use of wound vacuum-assisted closure does not allow coverage delay for open tibia fractures","volume":"121","author":"Bhattacharyya","year":"2008","journal-title":"Plast Reconstr Surg"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib34","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s00113-007-1360-1","volume":"111","author":"Brem","year":"2008","journal-title":"Unfallchirurg"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/BOT.0b013e31802cbc54","article-title":"The use of negative-pressure wound therapy (NPWT) in the temporary treatment of soft-tissue injuries associated with high-energy open tibial shaft fractures","volume":"21","author":"Dedmond","year":"2007","journal-title":"J Orthop Trauma"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib36","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1097\/01.prs.0000201225.07427.85","article-title":"Limb-threatening extravasation injury: topical negative pressure and limb salvage","volume":"117","author":"Goon","year":"2006","journal-title":"Plast Reconstr Surg"},{"issue":"10","key":"10.1016\/j.cpm.2009.08.002_bib37","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/00005131-200311000-00004","article-title":"Vacuum-assisted wound closure (VAC therapy) for the management of patients with high-energy soft tissue injuries","volume":"17","author":"Herscovici","year":"2003","journal-title":"J Orthop Trauma"},{"issue":"Suppl 5","key":"10.1016\/j.cpm.2009.08.002_bib38","first-page":"S9","article-title":"The efficacy of negative pressure wound therapy in the management of lower extremity trauma: review of clinical evidence","volume":"38","author":"Kanakaris","year":"2007","journal-title":"Injury"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib39","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/01.ASW.0000305451.71811.d5","article-title":"Early intervention of negative pressure wound therapy using vacuum-assisted closure in trauma patients: impact on hospital length of stay and cost","volume":"22","author":"Kaplan","year":"2009","journal-title":"Adv Skin Wound Care"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib40","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1097\/PRS.0b013e31816a8d9d","article-title":"Subatmospheric pressure dressing as a bridge to free tissue transfer in the treatment of open tibia fractures","volume":"121","author":"Rinker","year":"2008","journal-title":"Plast Reconstr Surg"},{"issue":"Suppl 10","key":"10.1016\/j.cpm.2009.08.002_bib41","doi-asserted-by":"crossref","first-page":"S152","DOI":"10.1097\/BOT.0b013e318188e2d7","article-title":"Negative pressure wound therapy with reticulated open cell foam-adjunctive treatment in the management of traumatic wounds of the leg: a review of the literature","volume":"22","author":"Schlatterer","year":"2008","journal-title":"J Orthop Trauma"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib42","first-page":"1301","article-title":"Negative pressure wound therapy to treat hematomas and surgical incisions following high-energy trauma","volume":"60","author":"Stannard","year":"2006","journal-title":"J\u00a0Trauma"},{"issue":"Suppl 10","key":"10.1016\/j.cpm.2009.08.002_bib43","doi-asserted-by":"crossref","first-page":"S146","DOI":"10.1097\/BOT.0b013e318188e2bc","article-title":"The versatility of negative pressure wound therapy with reticulated open cell foam for soft tissue management after severe musculoskeletal trauma","volume":"22","author":"Tarkin","year":"2008","journal-title":"J Orthop Trauma"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib44","doi-asserted-by":"crossref","first-page":"33","DOI":"10.12968\/jowc.2007.16.1.26987","article-title":"Role of topical negative pressure in pressure ulcer management","volume":"16","author":"Mandal","year":"2007","journal-title":"J\u00a0Wound Care"},{"issue":"11A Suppl","key":"10.1016\/j.cpm.2009.08.002_bib45","first-page":"5S","article-title":"Incorporating negative pressure therapy into the management strategy for pressure ulcers","volume":"50","author":"Niezgoda","year":"2004","journal-title":"Ostomy Wound Manage"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib46","first-page":"26","article-title":"Vacuum assisted wound closure in patients with lower extremity arterial disease. The experience from two tertiary referral-centres","volume":"28","author":"Nordmyr","year":"2009","journal-title":"Int Angiol"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib47","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1097\/01.ta.0000241150.15342.da","article-title":"Experience with wound VAC and delayed primary closure of contaminated soft tissue injuries in Iraq","volume":"61","author":"Leininger","year":"2006","journal-title":"J Trauma"},{"issue":"8","key":"10.1016\/j.cpm.2009.08.002_bib48","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.burns.2005.03.003","article-title":"The use of topical negative pressure in a paediatric patient with extensive burns","volume":"31","author":"Schintler","year":"2005","journal-title":"Burns"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib49","first-page":"16","article-title":"Adjuvant dressing for negative pressure wound therapy in burns","volume":"52","author":"Terrazas","year":"2006","journal-title":"Ostomy Wound Manage"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib50","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD006215.pub2","article-title":"Topical negative pressure (TNP) for partial thickness burns","author":"Wasiak","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib51","first-page":"44","article-title":"Negative pressure wound therapy in the adjunctive management of necrotizing fascitis: examining clinical outcomes","volume":"54","author":"Baharestani","year":"2008","journal-title":"Ostomy Wound Manage"},{"issue":"9","key":"10.1016\/j.cpm.2009.08.002_bib52","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1177\/000313480807400907","article-title":"Necrotizing fasciitis with no mortality or limb loss","volume":"74","author":"Martin","year":"2008","journal-title":"Am Surg"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib53","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1177\/1534734609331991","article-title":"Giant VAC in a patient with extensive necrotizing fasciitis","volume":"8","author":"Steinstraesser","year":"2009","journal-title":"Int J Low Extrem Wounds"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib54","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/micr.20512","article-title":"A critical evaluation of the concomitant use of the implantable Doppler probe and the vacuum assisted closure system in free tissue transfer","volume":"28","author":"Bannasch","year":"2008","journal-title":"Microsurgery"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib55","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1742-481X.2007.00362.x","article-title":"The role of the vacuum-assisted closure therapy in the salvage of venous congestion of the free flap: case report","volume":"5","author":"Uygur","year":"2008","journal-title":"Int Wound J"},{"issue":"Suppl 3","key":"10.1016\/j.cpm.2009.08.002_bib56","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1111\/j.1529-8019.2008.00238.x","article-title":"Calciphylaxis: a case report","volume":"21","author":"Strippoli","year":"2008","journal-title":"Dermatol Ther"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib57","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1742-481X.2006.00231.x","article-title":"Negative pressure wound therapy: treating a venomous insect bite","volume":"4","author":"Miller","year":"2007","journal-title":"Int Wound J"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib58","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1177\/1534734607313914","article-title":"Nonvenomous bite injuries of the foot: case reports and review of the literature","volume":"7","author":"Donate","year":"2008","journal-title":"Int J Low Extrem Wounds"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib59","first-page":"4","article-title":"Vacuum-assisted closure (VAC) therapy in the management of wound infection following renal transplantation","volume":"5","author":"Shrestha","year":"2007","journal-title":"Kathmandu Univ Med J (KUMJ)"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib60","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1365-4632.2009.03967.x","article-title":"Eumycotic mycetoma caused by Madurella mycetomatis successfully treated with antifungals, surgery, and topical negative pressure therapy","volume":"48","author":"Estrada-Chavez","year":"2009","journal-title":"Int J Dermatol"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib61","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1191\/0269216306pm1117cr","article-title":"Use of vacuum assisted closure therapy in the palliation of a malignant wound","volume":"20","author":"Ford-Dunn","year":"2006","journal-title":"Palliat Med"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib62","doi-asserted-by":"crossref","first-page":"171","DOI":"10.7547\/0950171","article-title":"Ulceration of pyoderma gangrenosum treated with negative pressure wound therapy","volume":"95","author":"Geller","year":"2005","journal-title":"J Am Podiatr Med Assoc"},{"issue":"10","key":"10.1016\/j.cpm.2009.08.002_bib63","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1001\/archderm.143.10.1249","article-title":"Negative pressure dressing in the management of pyoderma gangrenosum ulcer","volume":"143","author":"Ghersi","year":"2007","journal-title":"Arch Dermatol"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib64","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1016\/j.jvs.2008.07.059","article-title":"Use of vacuum-assisted closure (VAC) therapy in treating lymphatic complications after vascular procedures: new approach for lymphoceles","volume":"48","author":"Hamed","year":"2008","journal-title":"J Vasc Surg"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib65","doi-asserted-by":"crossref","first-page":"223","DOI":"10.2310\/7750.2008.07073","article-title":"Coverage of exposed bones and joints in critically ill patients: lower extremity salvage with topical negative pressure therapy","volume":"12","author":"Horch","year":"2008","journal-title":"J Cutan Med Surg"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib66","doi-asserted-by":"crossref","first-page":"249","DOI":"10.12968\/jowc.2004.13.6.26629","article-title":"Is vacuum assisted closure a valid technique for debriding chronic leg ulcers?","volume":"13","author":"Loree","year":"2004","journal-title":"J Wound Care"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib67","doi-asserted-by":"crossref","first-page":"622","DOI":"10.2106\/00004623-200503000-00022","article-title":"Use of topical negative pressure in the treatment of chronic osteomyelitis. A case report","volume":"87","author":"Lam","year":"2005","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib68","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.1524-475X.2009.00458.x","article-title":"Negative pressure wound treatment with polyvinyl alcohol foam and polyhexanide antiseptic solution instillation in posttraumatic osteomyelitis","volume":"17","author":"Timmers","year":"2009","journal-title":"Wound Repair Regen"},{"issue":"Suppl 1","key":"10.1016\/j.cpm.2009.08.002_bib69","doi-asserted-by":"crossref","first-page":"S160","DOI":"10.1055\/s-2006-921513","volume":"131","author":"Lehner","year":"2006","journal-title":"Zentralbl Chir"},{"issue":"7","key":"10.1016\/j.cpm.2009.08.002_bib70","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.ejso.2006.12.018","article-title":"Post-malignancy irradiation ulcers with exposed alloplastic materials can be salvaged with topical negative pressure therapy (TNP)","volume":"33","author":"Loos","year":"2007","journal-title":"Eur J Surg Oncol"},{"issue":"Suppl 3","key":"10.1016\/j.cpm.2009.08.002_bib71","first-page":"S239","article-title":"Prevention and management of infections associated with combat-related extremity injuries","volume":"64","author":"Murray","year":"2008","journal-title":"J Trauma"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib72","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1197\/j.jht.2007.12.007","article-title":"Management of large soft-tissue wounds with negative pressure therapy-lessons learned from the war zone","volume":"21","author":"Pirela-Cruz","year":"2008","journal-title":"J\u00a0Hand Ther"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib73","doi-asserted-by":"crossref","first-page":"111","DOI":"10.12968\/jowc.2006.15.3.26881","article-title":"Topical negative pressure in the treatment of infected wounds with exposed orthopaedic implants","volume":"15","author":"Pelham","year":"2006","journal-title":"J Wound Care"},{"issue":"9","key":"10.1016\/j.cpm.2009.08.002_bib74","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.jhsa.2008.05.019","article-title":"Chronic Mycobacterium infection of first dorsal web space after accidental Bacilli Calmette-Guerin injection in a health worker: case report","volume":"33","author":"Vigler","year":"2008","journal-title":"J Hand Surg [Am]"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib75","doi-asserted-by":"crossref","first-page":"234e","DOI":"10.1097\/01.prs.0000305394.80769.8b","article-title":"Vacuum-assisted closure over an external fixation device","volume":"121","author":"Lemmon","year":"2008","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib76","first-page":"538","article-title":"Vacuum-assisted wound closure (VAC) with simultaneous bone transport in the leg: a technical note","volume":"74","author":"Somanchi","year":"2008","journal-title":"Acta Orthop Belg"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib77","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.aorn.2008.02.014","article-title":"Surgical management of diabetic foot infections and amputations","volume":"87","author":"Zgonis","year":"2008","journal-title":"AORN"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib78","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.aorn.2008.02.002","article-title":"Plastic surgery reconstruction of the diabetic foot","volume":"87","author":"Zgonis","year":"2008","journal-title":"AORN"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib79","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1524-475X.2008.00448.x","article-title":"Depth of penetration of negative pressure wound therapy into underlying tissues","volume":"17","author":"Murphey","year":"2009","journal-title":"Wound Repair Regen"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib80","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1524-475X.2009.00461.x","article-title":"Negative-pressure wound therapy using gauze or open-cell polyurethane foam: similar early effects on pressure transduction and tissue contraction in an experimental porcine wound model","volume":"17","author":"Malmsjo","year":"2009","journal-title":"Wound Repair Regen"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib81","doi-asserted-by":"crossref","first-page":"031012","DOI":"10.1115\/1.2947358","article-title":"Effects of dressing type on 3D tissue microdeformations during negative pressure wound therapy: a computational study","volume":"131","author":"Wilkes","year":"2009","journal-title":"J\u00a0Biomech Eng"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib82","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1097\/PRS.0b013e31818237ac","article-title":"The mechanism of action of the vacuum-assisted closure device","volume":"122","author":"Scherer","year":"2008","journal-title":"Plast Reconstr Surg"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib83","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/0007-1226(88)90049-5","article-title":"The effect of mechanical stress on soft and hard tissue repair; a review","volume":"42","author":"Urschel","year":"1988","journal-title":"British Journal of Plastic Surgery"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib84","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1111\/j.1524-475X.2007.00295.x","article-title":"Effect of different frequencies of tensile strain on human dermal fibroblast proliferation and survival","volume":"15","author":"Nishimura","year":"2007","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.cpm.2009.08.002_bib85","article-title":"Efficacy and mechanisms of vacuum-assisted closure (VAC) therapy in promoting wound healing: a rodent model","author":"Jacobs","year":"2008","journal-title":"J\u00a0Plast Reconstr Aesthet Surg"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib86","first-page":"749","article-title":"Vacuum-assisted closure therapy increases local interleukin-8 and vascular endothelial growth factor levels in traumatic wounds","volume":"66","author":"Labler","year":"2009","journal-title":"J Trauma"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib87","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1007\/s00066-007-1560-1","article-title":"Expression of HIF-1 alpha in irradiated tissue is altered by topical negative-pressure therapy","volume":"183","author":"Grimm","year":"2007","journal-title":"Strahlenther Onkol"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib88","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/j.1524-475X.2008.00395.x","article-title":"The role of topical negative pressure in wound repair: expression of biochemical markers in wound fluid during wound healing","volume":"16","author":"Moues","year":"2008","journal-title":"Wound Repair Regen"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib89","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1742-481X.2008.00544.x","article-title":"Comparative analysis of global gene expression profiles between diabetic rat wounds treated with vacuum-assisted closure therapy, moist wound healing or gauze under suction","volume":"5","author":"Derrick","year":"2008","journal-title":"Int Wound J"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib90","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/00000637-199706000-00001","article-title":"Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation","volume":"38","author":"Morykwas","year":"1997","journal-title":"Ann Plast Surg"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib91","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1097\/01.PRS.0000136530.06899.92","article-title":"Complications of topical negative pressure therapy in small-diameter wounds","volume":"114","author":"Jones","year":"2004","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib92","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/1534734607313699","article-title":"A retained sponge is a complication of vacuum-assisted closure therapy","volume":"7","author":"Leijnen","year":"2008","journal-title":"Int J Low Extrem Wounds"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib93","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/01.sap.0000174361.52084.6e","article-title":"Vacuum-assisted closure treatment complicated by anasarca","volume":"55","author":"Friedman","year":"2005","journal-title":"Ann Plast Surg"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib94","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1097\/00000637-200111000-00013","article-title":"Effects of varying levels of subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine","volume":"47","author":"Morykwas","year":"2001","journal-title":"Ann Plast Surg"},{"issue":"10","key":"10.1016\/j.cpm.2009.08.002_bib95","doi-asserted-by":"crossref","first-page":"392","DOI":"10.12968\/jowc.2003.12.10.26549","article-title":"The cost-effectiveness of topical negative pressure versus other wound-healing therapies","volume":"12","author":"Neubauer","year":"2003","journal-title":"J Wound Care"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib96","doi-asserted-by":"crossref","first-page":"224","DOI":"10.12968\/jowc.2005.14.5.26776","article-title":"An economic evaluation of the use of TNP on full-thickness wounds","volume":"14","author":"Moues","year":"2005","journal-title":"J Wound Care"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib97","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.amjsurg.2006.01.013","article-title":"Negative pressure wound therapy with off-the-shelf components","volume":"192","author":"Bui","year":"2006","journal-title":"Am J Surg"},{"issue":"8\u20139","key":"10.1016\/j.cpm.2009.08.002_bib98","first-page":"613","article-title":"Our experience with a \u201chomemade\u201d vacuum-assisted closure system","volume":"10","author":"Shalom","year":"2008","journal-title":"Isr Med Assoc J"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib99","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/01.sap.0000111861.75927.4d","article-title":"Quantifying bacterial bioburden during negative pressure wound therapy: does the wound VAC enhance bacterial clearance?","volume":"52","author":"Weed","year":"2004","journal-title":"Ann Plast Surg"},{"key":"10.1016\/j.cpm.2009.08.002_bib100","article-title":"The paradox of negative pressure wound therapy \u2013 in vitro studies","author":"Kairinos","year":"2008","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib101","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/PRS.0b013e3181956551","article-title":"Negative-pressure wound therapy I: the paradox of negative-pressure wound therapy","volume":"123","author":"Kairinos","year":"2009","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib102","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/00000637-199706000-00002","article-title":"Vacuum-assisted closure: a new method for wound control and treatment: clinical experience","volume":"38","author":"Argenta","year":"1997","journal-title":"Ann Plast Surg"},{"issue":"6","key":"10.1016\/j.cpm.2009.08.002_bib103","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/j.1067-1927.2004.12602.x","article-title":"Effects of vacuum-assisted closure therapy on inguinal wound edge microvascular blood flow","volume":"12","author":"Wackenfors","year":"2004","journal-title":"Wound Repair Regen"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib104","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1097\/PRS.0b013e318196b97b","article-title":"Negative-pressure wound therapy II: negative-pressure wound therapy and increased perfusion. Just an illusion?","volume":"123","author":"Kairinos","year":"2009","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib105","first-page":"158","volume":"61","author":"Apostoli","year":"2008","journal-title":"Prof Inferm"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib106","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1080\/02844310802091586","article-title":"Vacuum-assisted closure of wounds and anxiety","volume":"42","author":"Keskin","year":"2008","journal-title":"Scand J Plast Reconstr Surg Hand Surg"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib107","doi-asserted-by":"crossref","first-page":"49","DOI":"10.12968\/jowc.2007.16.2.27008","article-title":"A pilot study on the effect of topical negative pressure on quality of life","volume":"16","author":"Mendonca","year":"2007","journal-title":"J Wound Care"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib108","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1524-475X.2007.00269.x","article-title":"Negative pressure therapy, a panacea or not?","volume":"15","author":"Greenhalgh","year":"2007","journal-title":"Wound Repair Regen"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib109","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.ejvs.2008.06.010","article-title":"Negative pressure wound therapy: a systematic review on effectiveness and safety","volume":"36","author":"Vikatmaa","year":"2008","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib110","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1001\/archsurg.2007.54","article-title":"Negative pressure wound therapy: a vacuum of evidence?","volume":"143","author":"Gregor","year":"2008","journal-title":"Arch Surg"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib111","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/j.1742-481X.2008.00485.x","article-title":"Retrospective clinical evaluation of gauze-based negative pressure wound therapy","volume":"5","author":"Campbell","year":"2008","journal-title":"Int Wound J"},{"issue":"4","key":"10.1016\/j.cpm.2009.08.002_bib112","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1097\/01.prs.0000178399.68254.13","article-title":"Interface dressings influence the delivery of topical negative-pressure therapy","volume":"116","author":"Jones","year":"2005","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib113","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/PRS.0b013e3181774835","article-title":"New continuous negative-pressure and irrigation treatment for infected wounds and intractable ulcers","volume":"122","author":"Chien","year":"2008","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"10.1016\/j.cpm.2009.08.002_bib114","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1742-481X.2007.00423.x","article-title":"Negative pressure wound therapy with instillation: a pilot study describing a new method for treating infected wounds","volume":"5","author":"Gabriel","year":"2008","journal-title":"Int Wound J"},{"issue":"2","key":"10.1016\/j.cpm.2009.08.002_bib115","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/01.WON.0000264834.18732.3b","article-title":"Advances in negative pressure wound therapy: the VAC instill","volume":"34","author":"Jerome","year":"2007","journal-title":"J\u00a0Wound Ostomy Continence Nurs"},{"issue":"5","key":"10.1016\/j.cpm.2009.08.002_bib116","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1097\/01.prs.0000279332.27374.69","article-title":"New continuous negative-pressure and irrigation treatment for infected wounds and intractable ulcers","volume":"120","author":"Kiyokawa","year":"2007","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.cpm.2009.08.002_bib117","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/PRS.0b013e31817747ea","article-title":"Does continuous negative-pressure and irrigation treatment really rinse the whole closed wound?","volume":"122","author":"Lee","year":"2008","journal-title":"Plast Reconstr Surg"}],"container-title":["Clinics in Podiatric Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891842209000676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891842209000676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T18:54:12Z","timestamp":1760208852000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0891842209000676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":117,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0891842209000676"],"URL":"https:\/\/doi.org\/10.1016\/j.cpm.2009.08.002","relation":{},"ISSN":["0891-8422"],"issn-type":[{"value":"0891-8422","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An Overview of Negative Pressure Wound Therapy for the Lower Extremity","name":"articletitle","label":"Article Title"},{"value":"Clinics in Podiatric Medicine and Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cpm.2009.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}