{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:16:03Z","timestamp":1760573763369,"version":"build-2065373602"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Podiatric Medicine and Surgery"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.cpm.2025.06.011","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T03:59:13Z","timestamp":1753156753000},"page":"757-766","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Amputation as an Alternative"],"prefix":"10.1016","volume":"42","author":[{"given":"Drishti","family":"Dhawan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry I.","family":"Rosenblum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cpm.2025.06.011_bib1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.2337\/dci22-0043","article-title":"Etiology, epidemiology, and disparities in the burden of diabetic foot ulcers","volume":"46","author":"McDermott","year":"2023","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cpm.2025.06.011_bib3","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1053\/j.jfas.2020.08.006","article-title":"Transmetatarsal amputation outcomes when utilized to address foot gangrene and infection: a retrospective chart review","volume":"60","author":"Harris","year":"2021","journal-title":"J Foot Ankle Surg"},{"issue":"6","key":"10.1016\/j.cpm.2025.06.011_bib4","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/j.jvs.2020.07.086","article-title":"\u201cA meta-analysis of mortality after minor amputation among patients with diabetes and\/or peripheral vascular disease\u201d","volume":"72","author":"Yammine","year":"2020","journal-title":"J Vasc Surg"},{"issue":"1","key":"10.1016\/j.cpm.2025.06.011_bib5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13047-020-00383-2","article-title":"Five year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer","volume":"13","author":"Armstrong","year":"2020","journal-title":"J Foot Ankle Res"},{"issue":"3","key":"10.1016\/j.cpm.2025.06.011_bib6","doi-asserted-by":"crossref","first-page":"651","DOI":"10.2337\/dc13-2176","article-title":"Burden of diabetic foot ulcers for medicare and private insurers","volume":"37","author":"Rice","year":"2014","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cpm.2025.06.011_bib7","doi-asserted-by":"crossref","DOI":"10.1002\/dmrr.3687","article-title":"IWGDF\/IDSA guidelines on the diagnosis and treatment of diabetes-related foot infections (IWGDF\/IDSA 2023)","volume":"40","author":"Senneville","year":"2024","journal-title":"Diabetes Metab Res Rev"},{"year":"2023","series-title":"Functional limb salvage: the multidisciplinary team approach","key":"10.1016\/j.cpm.2025.06.011_bib8"},{"key":"10.1016\/j.cpm.2025.06.011_bib9","series-title":"Mandell, douglas, and bennett's principles and practice of infectious diseases","article-title":"Diagnosis and management of diabetic foot infections","author":"Lipsky","year":"2019"},{"issue":"1","key":"10.1016\/j.cpm.2025.06.011_bib10","article-title":"Treating diabetic foot osteomyelitis: a practical state-of-the-art update","volume":"38","author":"Lipsky","year":"2021","journal-title":"Diabet Med"},{"issue":"2","key":"10.1016\/j.cpm.2025.06.011_bib11","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1177\/15347346211009403","article-title":"Conservative surgery for diabetic foot osteomyelitis is not associated with longer survival time without recurrence of foot ulcer when compared with amputation","volume":"22","author":"Arag\u00f3n-S\u00e1nchez","year":"2023","journal-title":"Int J Low Extrem Wounds"},{"issue":"11","key":"10.1016\/j.cpm.2025.06.011_bib12","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1177\/10711007231194046","article-title":"Comparative efficacy of conservative surgery vs minor amputation for diabetic foot osteomyelitis","volume":"44","author":"Sch\u00f6ni","year":"2023","journal-title":"Foot Ankle Int"},{"issue":"2","key":"10.1016\/j.cpm.2025.06.011_bib13","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.dsx.2018.12.021","article-title":"Operative versus non-operative treatment in diabetic dry toe gangrene","volume":"13","author":"Al","year":"2019","journal-title":"Diabetes Metab Syndr"},{"issue":"2","key":"10.1016\/j.cpm.2025.06.011_bib14","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1177\/1534734612447617","article-title":"Clinical-pathological characterization of diabetic foot infections: grading the severity of osteomyelitis","volume":"11","author":"Arag\u00f3n-S\u00e1nchez","year":"2012","journal-title":"Int J Low Extrem Wounds"},{"issue":"3","key":"10.1016\/j.cpm.2025.06.011_bib15","doi-asserted-by":"crossref","first-page":"789","DOI":"10.2337\/dc13-1526","article-title":"Antibiotics versus conservative surgery for treating diabetic foot osteomyelitis: a randomized comparative trial","volume":"37","author":"L\u00e1zaro-Mart\u00ednez","year":"2014","journal-title":"Diabetes Care"},{"issue":"6","key":"10.1016\/j.cpm.2025.06.011_bib16","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1053\/j.jfas.2014.06.011","article-title":"Self-reported quality of life and diabetic foot infections","volume":"53","author":"Raspovic","year":"2014","journal-title":"J Foot Ankle Surg"},{"key":"10.1016\/j.cpm.2025.06.011_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.diabres.2023.111061","article-title":"Health-related quality of life in people with different diabetes- related foot ulcer health states: a cross-sectional study of healed, non-infected, infected, hospitalised and amputated ulcer states","volume":"207","author":"Byrnes","year":"2024","journal-title":"Diabetes Res Clin Pract"},{"issue":"11","key":"10.1016\/j.cpm.2025.06.011_bib18","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.3113\/FAI.2008.1074","article-title":"Quality of life with diabetes-associated foot complications: comparison between lower-limb amputation and chronic foot ulceration","volume":"29","author":"Boutoille","year":"2008","journal-title":"Foot Ankle Int"},{"issue":"3","key":"10.1016\/j.cpm.2025.06.011_bib19","doi-asserted-by":"crossref","DOI":"10.1002\/dmrr.2867","article-title":"Minor amputation does not negatively affect health-related quality of life as compared with conservative treatment in patients with a diabetic foot ulcer: an observational study","volume":"33","author":"Pickwell","year":"2017","journal-title":"Diabetes Metab Res Rev"},{"issue":"11","key":"10.1016\/j.cpm.2025.06.011_bib20","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1302\/0301-620X.99B11.BJJ-2016-0793.R2","article-title":"Multiple limb salvage attempts for diabetic foot infections: is it worth it?","volume":"99-B","author":"Hong","year":"2017","journal-title":"Bone Joint Lett J"},{"issue":"3","key":"10.1016\/j.cpm.2025.06.011_bib21","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1111\/dme.12060","article-title":"Self-reported outcomes of trans-tibial amputations for non- reconstructable charcot neuroarthropathy in patients with diabetes: a preliminary report","volume":"30","author":"Wukich","year":"2013","journal-title":"Diabet Med"},{"issue":"18","key":"10.1016\/j.cpm.2025.06.011_bib22","doi-asserted-by":"crossref","first-page":"4046","DOI":"10.1002\/cncr.24458","article-title":"Bone and soft tissue sarcomas are often curable--but at what cost?: a call to arms (and legs)","volume":"115","author":"Barr","year":"2009","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.cpm.2025.06.011_bib23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1586\/erp.10.91","article-title":"Quality of life following limb-salvage surgery for bone sarcomas","volume":"11","author":"Ruggieri","year":"2011","journal-title":"Expert Rev Pharmacoecon Outcomes Res"},{"issue":"3","key":"10.1016\/j.cpm.2025.06.011_bib24","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s13193-013-0229-8","article-title":"Limb salvage surgery in bone tumors: a retrospective study of 50 cases in a single center","volume":"4","author":"Chauhan","year":"2013","journal-title":"Indian J Surg Oncol"},{"issue":"17","key":"10.1016\/j.cpm.2025.06.011_bib25","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.2106\/JBJS.20.01320","article-title":"Outcomes following severe distal tibial, ankle, and\/or mid\/hindfoot trauma: Comparison of limb salvage and transtibial amputation (OUTLET)","volume":"103","year":"2021","journal-title":"J Bone Joint Surg Am"},{"issue":"8","key":"10.1016\/j.cpm.2025.06.011_bib26","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.1007\/s00402-023-04804-2","article-title":"Limb salvage versus primary amputation in Gustilo-Anderson IIIB and IIIC tibial fractures: a systematic review and meta-analysis","volume":"143","author":"Ng","year":"2023","journal-title":"Arch Orthop Trauma Surg"},{"issue":"8","key":"10.1016\/j.cpm.2025.06.011_bib27","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1177\/1071100713483116","article-title":"Cost comparison: limb salvage versus amputation in diabetic patients with charcot foot","volume":"34","author":"Gil","year":"2013","journal-title":"Foot Ankle Int"},{"issue":"12","key":"10.1016\/j.cpm.2025.06.011_bib28","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1097\/CORR.0000000000001416","article-title":"Is reconstruction of unstable midfoot charcot neuroarthropathy cost effective from a us payer's perspective?","volume":"478","author":"Albright","year":"2020","journal-title":"Clin Orthop Relat Res"},{"issue":"9","key":"10.1016\/j.cpm.2025.06.011_bib29","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/S0003-9993(97)90056-3","article-title":"Therapeutic footwear: enhanced function in people with diabetes and transmetatarsal amputation","volume":"78","author":"Mueller","year":"1997","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"10.1016\/j.cpm.2025.06.011_bib30","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.jvs.2024.04.026","article-title":"Prosthetic fitting and mortality after major lower extremity amputation","volume":"80","author":"Forrester","year":"2024","journal-title":"J Vasc Surg"}],"container-title":["Clinics in Podiatric Medicine and Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891842225000709?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0891842225000709?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T04:52:33Z","timestamp":1760503953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0891842225000709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0891842225000709"],"URL":"https:\/\/doi.org\/10.1016\/j.cpm.2025.06.011","relation":{},"ISSN":["0891-8422"],"issn-type":[{"type":"print","value":"0891-8422"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Amputation as an Alternative","name":"articletitle","label":"Article Title"},{"value":"Clinics in Podiatric Medicine and Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cpm.2025.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}