{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T03:15:58Z","timestamp":1790478958709,"version":"4.1.0"},"reference-count":146,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["FKZ 01KG1802"],"award-info":[{"award-number":["FKZ 01KG1802"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Psychology Review"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.cpr.2020.101953","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T20:02:51Z","timestamp":1606766571000},"page":"101953","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":91,"special_numbering":"C","title":["Mediators and mechanisms of change in internet- and mobile-based interventions for depression: A systematic review"],"prefix":"10.1016","volume":"83","author":[{"given":"Matthias","family":"Domhardt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Steubl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Boettcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Buntrock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eirini","family":"Karyotaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David D.","family":"Ebert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pim","family":"Cuijpers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Baumeister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cpr.2020.101953_bb0005","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.cpr.2009.11.004","article-title":"Emotion-regulation strategies across psychopathology: A meta-analytic review","volume":"30","author":"Aldao","year":"2010","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0010","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/wps.20610","article-title":"Internet-delivered psychological treatments: From innovation to implementation","volume":"18","author":"Andersson","year":"2019","journal-title":"World Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0015","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0749-3797(18)30622-6","article-title":"Screening for depression in well older adults: Evaluation of a short form of the CES-D","volume":"10","author":"Andresen","year":"1994","journal-title":"American Journal of Preventive Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0020","first-page":"77","article-title":"The efficacy and mechanism of online positive psychological intervention (PPI) on improving well-being among Chinese university students: A pilot study of the best possible self (BPS) intervention","volume":"10","author":"Auyeung","year":"2018","journal-title":"Journal of Happiness Studies"},{"key":"10.1016\/j.cpr.2020.101953_bb0025","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.brat.2018.08.003","article-title":"A randomized controlled trial of three smartphone apps for enhancing public mental health","volume":"109","author":"Bakker","year":"2018","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0030","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0146-6402(78)90002-4","article-title":"Self-efficacy: Toward a unifying theory of behavioral change","volume":"1","author":"Bandura","year":"1978","journal-title":"Advances in Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0035","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","article-title":"The moderator\u2013mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations","volume":"51","author":"Baron","year":"1986","journal-title":"Journal of Personality and Social Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001454","article-title":"Comparative efficacy of seven psychotherapeutic interventions for patients with depression: A network meta-analysis","volume":"10","author":"Barth","year":"2013","journal-title":"PLoS Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0045","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0140-6736(17)30158-7","article-title":"Behavioural activation training for depression","volume":"389","author":"Baumeister","year":"2017","journal-title":"The Lancet"},{"key":"10.1016\/j.cpr.2020.101953_bb0050","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1055\/a-0592-0264","article-title":"Blended Psychotherapy \u2013 verzahnte Psychotherapie: Das Beste aus zwei Welten?","volume":"19","author":"Baumeister","year":"2018","journal-title":"PiD - Psychotherapie im Dialog"},{"key":"10.1016\/j.cpr.2020.101953_bb0055","series-title":"Cognitive therapy of depression","author":"Beck","year":"1979"},{"key":"10.1016\/j.cpr.2020.101953_bb0060","series-title":"Manual for the Beck depression inventory-II","author":"Beck","year":"1996"},{"key":"10.1016\/j.cpr.2020.101953_bb0065","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1177\/0049124103260222","article-title":"Autoregressive latent trajectory (ALT) models a synthesis of two traditions","volume":"32","author":"Bollen","year":"2004","journal-title":"Sociological Methods & Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0070","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1037\/0022-006X.66.1.136","article-title":"What is the scientific meaning of empirically supported therapy?","volume":"66","author":"Borkovec","year":"1998","journal-title":"Journal of Consulting and Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0075","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1001\/jama.2016.4326","article-title":"Effect of a web-based guided self-help intervention for prevention of major depression in adults with subthreshold depression: A randomized clinical trial","volume":"315","author":"Buntrock","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.cpr.2020.101953_bb0080","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1207\/S15328007SEM1002_5","article-title":"Investigation of mediational processes using parallel process latent growth curve Modeling","volume":"10","author":"Cheong","year":"2003","journal-title":"Structural Equation Modeling: A Multidisciplinary Journal"},{"key":"10.1016\/j.cpr.2020.101953_bb0085","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1002\/da.22242","article-title":"Six-month postintervention depression and disability outcomes of in-home telehealth problem-solving therapy for depressed, low-income homebound older adults","volume":"31","author":"Choi","year":"2014","journal-title":"Depression and Anxiety"},{"key":"10.1016\/j.cpr.2020.101953_bb0090","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/s12888-014-0272-1","article-title":"Effects of mental health self-efficacy on outcomes of a mobile phone and web intervention for mild-to-moderate depression, anxiety and stress: Secondary analysis of a randomised controlled trial","volume":"14","author":"Clarke","year":"2014","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0095","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1037\/0021-843X.112.4.558","article-title":"Testing mediational models with longitudinal data: Questions and tips in the use of structural equation modeling","volume":"112","author":"Cole","year":"2003","journal-title":"Journal of Abnormal Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0100","doi-asserted-by":"crossref","first-page":"S112","DOI":"10.1016\/j.amepre.2007.01.022","article-title":"The multiphase optimization strategy (MOST) and the sequential multiple assignment randomized trial (SMART): New methods for more potent eHealth interventions","volume":"32","author":"Collins","year":"2007","journal-title":"American Journal of Preventive Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0105","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1176\/appi.ps.201100518","article-title":"Services for adolescents with psychiatric disorders: 12-month data from the National Comorbidity Survey-Adolescent","volume":"65","author":"Costello","year":"2014","journal-title":"Psychiatric services (Washington, D.C.)"},{"key":"10.1016\/j.cpr.2020.101953_bb0110","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cpr.2015.08.003","article-title":"The effects of cognitive behavior therapy for adult depression on dysfunctional thinking: A meta-analysis","volume":"42","author":"Cristea","year":"2015","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0115","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1017\/S2045796015000785","article-title":"The future of psychotherapy research: Stop the waste and focus on issues that matter","volume":"25","author":"Cuijpers","year":"2016","journal-title":"Epidemiology and Psychiatric Sciences"},{"key":"10.1016\/j.cpr.2020.101953_bb0120","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/wps.20661","article-title":"Targets and outcomes of psychotherapies for mental disorders: An overview","volume":"18","author":"Cuijpers","year":"2019","journal-title":"World Psychiatry"},{"issue":"1","key":"10.1016\/j.cpr.2020.101953_bb0125","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/10503307.2017.1395922","article-title":"Component studies of psychological treatments of adult depression: A systematic review and meta-analysis","author":"Cuijpers","year":"2017","journal-title":"Psychotherapy Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0130","first-page":"1","article-title":"The effects of fifteen evidence-supported therapies for adult depression: A meta-analytic review","author":"Cuijpers","year":"2019","journal-title":"Psychotherapy Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0135","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2020.0164","article-title":"Psychotherapy for depression across different age groups: A systematic review and Meta-analysis","author":"Cuijpers","year":"2020","journal-title":"JAMA psychiatry."},{"key":"10.1016\/j.cpr.2020.101953_bb0140","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1001\/jamapsychiatry.2019.0268","article-title":"Effectiveness and acceptability of cognitive behavior therapy delivery formats in adults with depression: A network Meta-analysis","volume":"76","author":"Cuijpers","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0145","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1146\/annurev-clinpsy-050718-095424","article-title":"The role of common factors in psychotherapy outcomes","volume":"15","author":"Cuijpers","year":"2019","journal-title":"Annual Review of Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0150","first-page":"174","article-title":"A conceptual and methodological analysis of the nonspecifics argument","volume":"12","author":"DeRubeis","year":"2005","journal-title":"Clinical Psychology: Science and Practice"},{"key":"10.1016\/j.cpr.2020.101953_bb0155","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1080\/15622975.2018.1467041","article-title":"Psychotherapy of adjustment disorders: Current state and future directions","volume":"19","author":"Domhardt","year":"2018","journal-title":"The World Journal of Biological Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0165","series-title":"Psychologie in der Gesundheitsf\u00f6rderung","first-page":"397","article-title":"Internet- und mobilebasierte Interventionen","author":"Domhardt","year":"2018"},{"key":"10.1016\/j.cpr.2020.101953_bb0170","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/da.22860","article-title":"Internet- and mobile-based interventions for anxiety disorders: A meta-analytic review of intervention components","volume":"36","author":"Domhardt","year":"2019","journal-title":"Depression and Anxiety"},{"key":"10.1016\/j.cpr.2020.101953_bb0175","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jad.2020.06.059","article-title":"Are internet- and mobile-based interventions effective in adults with diagnosed panic disorder and\/or agoraphobia? A systematic review and meta-analysis","volume":"276","author":"Domhardt","year":"2020","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.cpr.2020.101953_bb0180","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1177\/1524838014557288","article-title":"Resilience in survivors of child sexual abuse: A systematic review of the literature","volume":"16","author":"Domhardt","year":"2015","journal-title":"Trauma, Violence & Abuse"},{"key":"10.1016\/j.cpr.2020.101953_bb0185","first-page":"1","article-title":"Internet- and Mobile-based interventions for mental and somatic conditions in children and adolescents: A systematic review of Meta-analyses","author":"Domhardt","year":"2018","journal-title":"Zeitschrift f\u00fcr Kinder- und Jugendpsychiatrie und Psychotherapie"},{"key":"10.1016\/j.cpr.2020.101953_bb0195","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3389\/fpsyt.2017.00116","article-title":"Prevention of mental health disorders using internet and mobile-based interventions: A narrative review and recommendations for future research","volume":"8","author":"Ebert","year":"2017","journal-title":"Frontiers in Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0200","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1017\/S0033291716001562","article-title":"Does internet-based guided-self-help for depression cause harm? An individual participant data meta-analysis on deterioration rates and its moderators in randomized controlled trials","volume":"46","author":"Ebert","year":"2016","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0205","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1027\/1016-9040\/a000318","article-title":"Internet- and Mobile-based psychological interventions: Applications, efficacy, and potential for improving mental health","volume":"23","author":"Ebert","year":"2018","journal-title":"European Psychologist"},{"key":"10.1016\/j.cpr.2020.101953_bb0210","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0119895","article-title":"Internet and computer-based cognitive behavioral therapy for anxiety and depression in youth: A meta-analysis of randomized controlled outcome trials","volume":"10","author":"Ebert","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.cpr.2020.101953_bb0215","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S0140-6736(97)02419-7","article-title":"Language bias in randomised controlled trials published in English and German","volume":"350","author":"Egger","year":"1997","journal-title":"The Lancet"},{"key":"10.1016\/j.cpr.2020.101953_bb0220","doi-asserted-by":"crossref","first-page":"e306","DOI":"10.2196\/jmir.6588","article-title":"Blending face-to-face and internet-based interventions for the treatment of mental disorders in adults: Systematic review","volume":"19","author":"Erbe","year":"2017","journal-title":"Journal of Medical Internet Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0225","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/wps.20472","article-title":"The efficacy of smartphone-based mental health interventions for depressive symptoms: A meta-analysis of randomized controlled trials","volume":"16","author":"Firth","year":"2017","journal-title":"World Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0230","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.beth.2017.04.004","article-title":"Efficacy of guided iCBT for depression and mediation of change by cognitive skill acquisition","volume":"49","author":"Forand","year":"2018","journal-title":"Behavior Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0235","article-title":"Dismantling, personalising and optimising internet cognitive-behavioural therapy for depression: A study protocol for individual participant data component network meta-analysis","volume":"8","author":"Furukawa","year":"2019","journal-title":"BMJ Open"},{"key":"10.1016\/j.cpr.2020.101953_bb0240","first-page":"224","article-title":"Cognitive processes in cognitive therapy: Evaluation of the mechanisms of change in the treatment of depression","volume":"14","author":"Garratt","year":"2007","journal-title":"Clinical Psychology: Science and Practice"},{"key":"10.1016\/j.cpr.2020.101953_bb0245","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2019.2075","article-title":"Experimental therapeutics for digital mental health","author":"Graham","year":"2019","journal-title":"JAMA psychiatry."},{"key":"10.1016\/j.cpr.2020.101953_bb0250","doi-asserted-by":"crossref","first-page":"611","DOI":"10.2307\/25148742","article-title":"The nature of theory in information systems","volume":"30","author":"Gregor","year":"2006","journal-title":"MIS Quarterly"},{"key":"10.1016\/j.cpr.2020.101953_bb0255","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1146\/annurev-clinpsy-050817-084840","article-title":"Latent growth and dynamic structural equation models","volume":"14","author":"Grimm","year":"2018","journal-title":"Annual Review of Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0260","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0265","author":"Hayes"},{"key":"10.1016\/j.cpr.2020.101953_bb0270","series-title":"Introduction to mediation, moderation, and conditional process analysis: A regression-based approach. (Second edition). Methodology in the social sciences","author":"Hayes","year":"2018"},{"key":"10.1016\/j.cpr.2020.101953_bb0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpr.2020.101908","article-title":"A process-based approach to psychological diagnosis and treatment:The conceptual and treatment utility of an extended evolutionary meta model","volume":"82","author":"Hayes","year":"2020","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0280","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.brat.2018.10.005","article-title":"The role of the individual in the coming era of process-based therapy","volume":"117","author":"Hayes","year":"2019","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.brat.2019.103415","article-title":"Efficacy of an internet and app-based gratitude intervention in reducing repetitive negative thinking and mechanisms of change in the intervention\u2019s effect on anxiety and depression: Results from a randomized controlled trial","volume":"119","author":"Heckendorf","year":"2019","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0290","series-title":"Causal Inference","author":"Hern\u00e1n","year":"2019"},{"key":"10.1016\/j.cpr.2020.101953_bb0295","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.cpr.2020.101953_bb0300","series-title":"Cochrane handbook for systematic reviews of interventions: Version 5.1.0 (updated march 2011)","year":"2011"},{"key":"10.1016\/j.cpr.2020.101953_bb0305","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1037\/ccp0000310","article-title":"Interpretation training to target repetitive negative thinking in generalized anxiety disorder and depression","volume":"86","author":"Hirsch","year":"2018","journal-title":"Journal of Consulting and Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0310","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.beth.2009.01.007","article-title":"The science of cognitive therapy","volume":"44","author":"Hofmann","year":"2013","journal-title":"Behavior Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.cpr.2020.101824","article-title":"Beyond linear mediation: Toward a dynamic network approach to study treatment processes","volume":"76","author":"Hofmann","year":"2020","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0320","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/2167702618772296","article-title":"The future of intervention science: Process-based therapy","volume":"7","author":"Hofmann","year":"2019","journal-title":"Clinical Psychological Science"},{"key":"10.1016\/j.cpr.2020.101953_bb0325","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/wps.20665","article-title":"Moderation, mediation, and moderated mediation","volume":"18","author":"Hollon","year":"2019","journal-title":"World Psychiatry"},{"issue":"Suppl. 1","key":"10.1016\/j.cpr.2020.101953_bb0330","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/16506070902915667","article-title":"Mediating the effects of cognitive therapy for depression","volume":"38","author":"Hollon","year":"2009","journal-title":"Cognitive Behaviour Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0335","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1037\/0033-2909.102.1.139","article-title":"Causal mediation of change in treatment for depression: Discriminating between nonspecificity and noncausality","volume":"102","author":"Hollon","year":"1987","journal-title":"Psychological Bulletin"},{"key":"10.1016\/j.cpr.2020.101953_bb0340","series-title":"The Oxford handbook of cognitive and behavioral therapies","article-title":"Behavioral activation","author":"Hopko","year":"2016"},{"key":"10.1016\/j.cpr.2020.101953_bb0345","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1057-7408(07)70020-7","article-title":"A meditation on mediation: Evidence that structural equations models perform better than regressions","volume":"17","author":"Iacobucci","year":"2007","journal-title":"Journal of Consumer Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0350","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1037\/0022-006X.64.2.295","article-title":"A component analysis of cognitive-behavioral treatment for depression","volume":"64","author":"Jacobson","year":"1996","journal-title":"Journal of Consulting and Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0355","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1037\/0021-9010.69.2.307","article-title":"Mediators, moderators, and tests for mediation","volume":"69","author":"James","year":"1984","journal-title":"Journal of Applied Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0360","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cpp.514","article-title":"Identifying mechanisms of change in psychotherapy: Mediators of treatment outcome","volume":"14","author":"Johansson","year":"2007","journal-title":"Clinical Psychology & Psychotherapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0365","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1037\/a0019245","article-title":"The mediating role of insight for long-term improvements in psychodynamic therapy","volume":"78","author":"Johansson","year":"2010","journal-title":"Journal of Consulting and Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0370","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.cpr.2018.06.007","article-title":"Do guided internet-based interventions result in clinically relevant changes for patients with depression? An individual participant data meta-analysis","volume":"63","author":"Karyotaki","year":"2018","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0375","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1017\/S0033291718000648","article-title":"Is self-guided internet-based cognitive behavioural therapy (iCBT) harmful? An individual participant data meta-analysis","volume":"48","author":"Karyotaki","year":"2018","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0380","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1001\/jamapsychiatry.2017.0044","article-title":"Efficacy of self-guided internet-based cognitive Behavioral therapy in the treatment of depressive symptoms: A Meta-analysis of individual participant data","volume":"74","author":"Karyotaki","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0385","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.2196\/jmir.1858","article-title":"Self-monitoring using mobile phones in the early stages of adolescent depression: Randomized controlled trial","volume":"14","author":"Kauer","year":"2012","journal-title":"Journal of Medical Internet Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0390","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s10608-018-9920-y","article-title":"The processes of cognitive Behavioral therapy: A review of Meta-analyses","volume":"42","author":"Kazantzis","year":"2018","journal-title":"Cognitive Therapy and Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0395","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.clinpsy.3.022806.091432","article-title":"Mediators and mechanisms of change in psychotherapy research","volume":"3","author":"Kazdin","year":"2007","journal-title":"Annual Review of Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0400","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1080\/10503300802448899","article-title":"Understanding how and why psychotherapy leads to change","volume":"19","author":"Kazdin","year":"2009","journal-title":"Psychotherapy Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0405","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1111\/1469-7610.00195","article-title":"Delineating mechanisms of change in child and adolescent therapy: Methodological issues and research recommendations","volume":"44","author":"Kazdin","year":"2003","journal-title":"Journal of Child Psychology and Psychiatry, and Allied Disciplines"},{"key":"10.1016\/j.cpr.2020.101953_bb0410","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev-publhealth-031912-114409","article-title":"The epidemiology of depression across cultures","volume":"34","author":"Kessler","year":"2013","journal-title":"Annual Review of Public Health"},{"key":"10.1016\/j.cpr.2020.101953_bb0415","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.jad.2017.07.021","article-title":"Internet- and mobile-based depression interventions for people with diagnosed depression: A systematic review and meta-analysis","volume":"223","author":"K\u00f6nigbauer","year":"2017","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.cpr.2020.101953_bb0420","doi-asserted-by":"crossref","DOI":"10.1001\/jamapsychiatry.2019.1965","article-title":"Is it time to ban the P value?","author":"Kraemer","year":"2019","journal-title":"JAMA psychiatry."},{"key":"10.1016\/j.cpr.2020.101953_bb0425","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1037\/0278-6133.27.2(Suppl.).S101","article-title":"How and why criteria defining moderators and mediators differ between the Baron & Kenny and MacArthur approaches","volume":"27","author":"Kraemer","year":"2008","journal-title":"Health Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0430","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1001\/archpsyc.59.10.877","article-title":"Mediators and moderators of treatment effects in randomized clinical trials","volume":"59","author":"Kraemer","year":"2002","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0435","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: Validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"Journal of General Internal Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0440","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1093\/geronb\/gbu030","article-title":"The efficacy of life-review as online-guided self-help for adults: A randomized trial","volume":"70","author":"Lamers","year":"2015","journal-title":"The journals of gerontology"},{"key":"10.1016\/j.cpr.2020.101953_bb0445","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.cpr.2007.01.007","article-title":"Some methodological and statistical issues in the study of change processes in psychotherapy","volume":"27","author":"Laurenceau","year":"2007","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0450","doi-asserted-by":"crossref","first-page":"16","DOI":"10.13109\/zptm.2018.64.1.16","article-title":"On mechanisms of change in psychodynamic therapy","volume":"64","author":"Leichsenring","year":"2018","journal-title":"Zeitschrift f\u00fcr Psychosomatische Medizin und Psychotherapie"},{"key":"10.1016\/j.cpr.2020.101953_bb0455","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.cpr.2016.09.004","article-title":"Mechanisms of change in psychotherapy for depression: An empirical update and evaluation of research aimed at identifying psychological mediators","volume":"50","author":"Lemmens","year":"2016","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0460","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/0145445516659645","article-title":"Web-based acceptance and commitment therapy for mental health problems in college students: A randomized controlled trial","volume":"41","author":"Levin","year":"2017","journal-title":"Behavior Modification"},{"key":"10.1016\/j.cpr.2020.101953_bb0465","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s13643-019-1044-2","article-title":"Acceptance and commitment therapy for chronic pain: Protocol of a systematic review and individual participant data meta-analysis","volume":"8","author":"Lin","year":"2019","journal-title":"Systematic Reviews"},{"key":"10.1016\/j.cpr.2020.101953_bb0470","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/wps.20673","article-title":"The efficacy of app-supported smartphone interventions for mental health problems: A meta-analysis of randomized controlled trials","volume":"18","author":"Linardon","year":"2019","journal-title":"World Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0475","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.cpr.2013.09.002","article-title":"Mechanisms of change in interpersonal therapy (IPT)","volume":"33","author":"Lipsitz","year":"2013","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0480","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1177\/0748175611432642","article-title":"Development and initial validation of the Counseling Center assessment of psychological symptoms\u201334","volume":"45","author":"Locke","year":"2012","journal-title":"Measurement and Evaluation in Counseling and Development"},{"key":"10.1016\/j.cpr.2020.101953_bb0485","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.cpr.2014.12.003","article-title":"It\u2019s complicated: The relation between cognitive change procedures, cognitive change, and symptom change in cognitive therapy for depression","volume":"41","author":"Lorenzo-Luaces","year":"2015","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0490","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0005-7967(94)00075-U","article-title":"The structure of negative emotional states: Comparison of the depression anxiety stress scales (DASS) with the Beck depression and anxiety inventories","volume":"33","author":"Lovibond","year":"1995","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0495","doi-asserted-by":"crossref","first-page":"e12711","DOI":"10.2196\/12711","article-title":"Exploring mediators of a guided web-based self-help intervention for people with HIV and depressive symptoms: Randomized controlled trial","volume":"6","author":"van Luenen","year":"2019","journal-title":"JMIR mental health"},{"key":"10.1016\/j.cpr.2020.101953_bb0500","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.3389\/fpsyg.2018.02090","article-title":"Effectiveness of online mindfulness-based interventions on psychological distress and the mediating role of emotion regulation","volume":"9","author":"Ma","year":"2018","journal-title":"Frontiers in Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0505","series-title":"Introduction to statistical mediation analysis. Multivariate applications series","author":"MacKinnon","year":"2017"},{"key":"10.1016\/j.cpr.2020.101953_bb0510","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1146\/annurev.psych.58.110405.085542","article-title":"Mediation analysis","volume":"58","author":"MacKinnon","year":"2007","journal-title":"Annual Review of Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0515","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1037\/1082-989X.7.1.83","article-title":"A comparison of methods to test mediation and other intervening variable effects","volume":"7","author":"MacKinnon","year":"2002","journal-title":"Psychological Methods"},{"key":"10.1016\/j.cpr.2020.101953_bb0520","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.cpr.2005.12.005","article-title":"The efficacy of problem solving therapy in reducing mental and physical health problems: A meta-analysis","volume":"27","author":"Malouff","year":"2007","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0525","first-page":"32","article-title":"Service utilization for lifetime mental disorders in U.S. adolescents: Results of the National Comorbidity Survey-Adolescent Supplement (NCS-A)","volume":"50","author":"Merikangas","year":"2011","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0530","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/jclp.22326","article-title":"Internet-based psychotherapy for adult depression: What about the mechanisms of change?","volume":"73","author":"Mogoase","year":"2017","journal-title":"Journal of Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0535","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ (Clinical research ed.)"},{"key":"10.1016\/j.cpr.2020.101953_bb0540","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1037\/met0000086","article-title":"Two-condition within-participant statistical mediation analysis: A path-analytic framework","volume":"22","author":"Montoya","year":"2017","journal-title":"Psychological Methods"},{"key":"10.1016\/j.cpr.2020.101953_bb0545","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.brat.2012.11.002","article-title":"Behavior change through automated e-mails: Mediation analysis of self-help strategy use for depressive symptoms","volume":"51","author":"Morgan","year":"2013","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0550","doi-asserted-by":"crossref","first-page":"e72","DOI":"10.2196\/jmir.4167","article-title":"Efficacy of a web-based, crowdsourced peer-to-peer cognitive reappraisal platform for depression: Randomized controlled trial","volume":"17","author":"Morris","year":"2015","journal-title":"Journal of Medical Internet Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0555","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/S2215-0366(17)30100-1","article-title":"Common versus specific factors in psychotherapy: Opening the black box: Opening the black box","volume":"4","author":"Mulder","year":"2017","journal-title":"The Lancet Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0560","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/d41586-018-01023-3","article-title":"Robust research needs many lines of evidence","volume":"553","author":"Munaf\u00f2","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.cpr.2020.101953_bb0565","series-title":"Mplus User\u2019s Guide","author":"Muth\u00e9n","year":"1998"},{"key":"10.1016\/j.cpr.2020.101953_bb0570","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.brat.2014.05.009","article-title":"Reductions in negative repetitive thinking and metacognitive beliefs during transdiagnostic internet cognitive behavioural therapy (iCBT) for mixed anxiety and depression","volume":"59","author":"Newby","year":"2014","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0575","series-title":"Applying causal inference methods in psychiatric","author":"Ohlsson","year":"2019"},{"key":"10.1016\/j.cpr.2020.101953_bb0580","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.brat.2016.07.008","article-title":"When less could be more: Investigating the effects of a brief internet-based imagery cognitive bias modification intervention in depression","volume":"84","author":"Pictet","year":"2016","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0585","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1186\/s12888-016-0841-6","article-title":"How and for whom does web-based acceptance and commitment therapy work? Mediation and moderation analyses of web-based ACT for depressive symptoms","volume":"16","author":"Pots","year":"2016","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0590","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.psc.2017.08.010","article-title":"Core mechanisms of cognitive Behavioral therapy for anxiety and depression: A review","volume":"40","author":"Powers","year":"2017","journal-title":"The Psychiatric Clinics of North America"},{"key":"10.1016\/j.cpr.2020.101953_bb0595","doi-asserted-by":"crossref","first-page":"879","DOI":"10.3758\/BRM.40.3.879","article-title":"Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models","volume":"40","author":"Preacher","year":"2008","journal-title":"Behavior Research Methods"},{"key":"10.1016\/j.cpr.2020.101953_bb0600","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1007\/s12671-018-0925-0","article-title":"The effects of an online mindfulness intervention on perceived stress, depression and anxiety in a non-clinical sample: A randomised waitlist control trial","volume":"9","author":"Querstret","year":"2018","journal-title":"Mindfulness"},{"key":"10.1016\/j.cpr.2020.101953_bb0605","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/014662167700100306","article-title":"The CES-D scale: A self-report depression scale for research in the general population","volume":"1","author":"Radloff","year":"1977","journal-title":"Applied Psychological Measurement"},{"key":"10.1016\/j.cpr.2020.101953_bb0610","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0140-6736(16)31140-0","article-title":"Cost and outcome of behavioural activation versus cognitive behavioural therapy for depression (COBRA): A randomised, controlled, non-inferiority trial","volume":"388","author":"Richards","year":"2016","journal-title":"The Lancet"},{"key":"10.1016\/j.cpr.2020.101953_bb0615","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.2337\/dc14-2519","article-title":"Depressive symptoms in a trial Behavioral family systems therapy for diabetes: A post hoc analysis of change","volume":"38","author":"Riley","year":"2015","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cpr.2020.101953_bb0620","series-title":"Publication bias in meta-analysis: Prevention, assessment and adjustments","year":"2005"},{"key":"10.1016\/j.cpr.2020.101953_bb0625","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1080\/16506073.2015.1008033","article-title":"Negative effects of internet interventions: A qualitative content analysis of patients\u2019 experiences with treatments delivered online","volume":"44","author":"Rozental","year":"2015","journal-title":"Cognitive Behaviour Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0630","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1037\/0022-0167.45.1.18","article-title":"Analyzing data from experimental studies: A latent variable structural equation modeling approach","volume":"45","author":"Russell","year":"1998","journal-title":"Journal of Counseling Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0635","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1080\/16506073.2018.1513554","article-title":"Mediation analyses of internet-facilitated cognitive behavioral intervention for maternal depression","volume":"48","author":"Seeley","year":"2019","journal-title":"Cognitive Behaviour Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0640","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.brat.2015.07.009","article-title":"Computerised CBT for depressed adolescents: Randomised controlled trial","volume":"73","author":"Smith","year":"2015","journal-title":"Behaviour Research and Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0645","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1080\/10705511.2011.557344","article-title":"Mediation analysis in a latent growth curve Modeling framework","volume":"18","author":"von Soest","year":"2011","journal-title":"Structural Equation Modeling: A Multidisciplinary Journal"},{"key":"10.1016\/j.cpr.2020.101953_bb0650","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jpsychires.2018.08.005","article-title":"Efficacy of the unified protocol for transdiagnostic treatment of comorbid psychopathology accompanying emotional disorders compared to treatments targeting single disorders","volume":"104","author":"Steele","year":"2018","journal-title":"Journal of Psychiatric Research"},{"key":"10.1016\/j.cpr.2020.101953_bb0655","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/s13643-019-1190-6","article-title":"Intervention components, mediators, and mechanisms of change of internet- and mobile-based interventions for post-traumatic stress disorder: Protocol for a systematic review and meta-analysis","volume":"8","author":"Steubl","year":"2019","journal-title":"Systematic Reviews"},{"key":"10.1016\/j.cpr.2020.101953_bb0660","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1017\/S1352465818000553","article-title":"Identifying the underlying mechanisms of change during acceptance and commitment therapy (ACT): A systematic review of contemporary mediation studies","volume":"47","author":"Stockton","year":"2019","journal-title":"Behavioural and Cognitive Psychotherapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0665","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1017\/S0033291714000701","article-title":"Stepped care treatment delivery for depression: A systematic review and meta-analysis","volume":"45","author":"van Straten","year":"2015","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0670","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/16506073.2017.1347195","article-title":"Increased skills usage statistically mediates symptom reduction in self-guided internet-delivered cognitive-behavioural therapy for depression and anxiety: A randomised controlled trial","volume":"47","author":"Terides","year":"2017","journal-title":"Cognitive Behaviour Therapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0675","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/cpp.1822","article-title":"Towards a taxonomy of common factors in psychotherapy-results of an expert survey","volume":"21","author":"Tschacher","year":"2014","journal-title":"Clinical Psychology & Psychotherapy"},{"key":"10.1016\/j.cpr.2020.101953_bb0680","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cpr.2015.02.001","article-title":"A systematic review of mechanisms of change in mindfulness-based cognitive therapy in the treatment of recurrent major depressive disorder","volume":"37","author":"van der Velden","year":"2015","journal-title":"Clinical Psychology Review"},{"key":"10.1016\/j.cpr.2020.101953_bb0685","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1002\/jclp.22656","article-title":"Pilot evaluation of a web-based acceptance and commitment therapy program to promote mental health skills in university students","volume":"74","author":"Viskovich","year":"2018","journal-title":"Journal of Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0690","article-title":"Randomized controlled trial of a web-based acceptance and commitment therapy (ACT) program to promote mental health in university students","author":"Viskovich","year":"2019","journal-title":"Journal of Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0695","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0140-6736(16)31678-6","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990\u20132015: A systematic analysis for the global burden of disease study 2015","volume":"388","author":"Vos","year":"2016","journal-title":"The Lancet"},{"key":"10.1016\/j.cpr.2020.101953_bb0700","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/wps.20238","article-title":"How important are the common factors in psychotherapy? An update","volume":"14","author":"Wampold","year":"2015","journal-title":"World Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0705","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jbtep.2009.10.003","article-title":"Online cognitive behavioral therapy and problem-solving therapy for depressive symptoms: Exploring mechanisms of change","volume":"41","author":"Warmerdam","year":"2010","journal-title":"Journal of Behavior Therapy and Experimental Psychiatry"},{"key":"10.1016\/j.cpr.2020.101953_bb0710","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.invent.2018.04.002","article-title":"Efficacy and cost-effectiveness of guided and unguided internet- and mobile-based indicated transdiagnostic prevention of depression and anxiety (ICare prevent): A three-armed randomized controlled trial in four European countries","volume":"16","author":"Weisel","year":"2019","journal-title":"Internet Interventions"},{"key":"10.1016\/j.cpr.2020.101953_bb0715","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1080\/08870446.2017.1293054","article-title":"Working mechanisms of a web-based self-management intervention for cancer survivors: A randomised controlled trial","volume":"32","author":"Willems","year":"2017","journal-title":"Psychology & Health"},{"key":"10.1016\/j.cpr.2020.101953_bb0720","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1037\/a0033247","article-title":"Combining imagination and reason in the treatment of depression: A randomized controlled trial of internet-based cognitive-bias modification and internet-CBT for depression","volume":"81","author":"Williams","year":"2013","journal-title":"Journal of Consulting and Clinical Psychology"},{"key":"10.1016\/j.cpr.2020.101953_bb0725","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.amepre.2016.06.015","article-title":"Understanding and promoting effective engagement with digital behavior change interventions","volume":"51","author":"Yardley","year":"2016","journal-title":"American Journal of Preventive Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0730","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1017\/S003329171300175X","article-title":"Online cognitive-based intervention for depression: Exploring possible circularity in mechanisms of change","volume":"44","author":"van der Zanden","year":"2014","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.cpr.2020.101953_bb0735","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatrica Scandinavica"},{"key":"10.1016\/j.cpr.2020.101953_bb0740","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1001\/archpsyc.1965.01720310065008","article-title":"A self-rating depression scale","volume":"12","author":"Zung","year":"1965","journal-title":"Archives of General Psychiatry"}],"container-title":["Clinical Psychology Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272735820301410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272735820301410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T04:34:50Z","timestamp":1759466090000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272735820301410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":146,"alternative-id":["S0272735820301410"],"URL":"https:\/\/doi.org\/10.1016\/j.cpr.2020.101953","relation":{},"ISSN":["0272-7358"],"issn-type":[{"value":"0272-7358","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mediators and mechanisms of change in internet- and mobile-based interventions for depression: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Clinical Psychology Review","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cpr.2020.101953","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101953"}}