{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:25:16Z","timestamp":1786987516838,"version":"build-2736575974"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Pathogenesis and Therapy"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.cpt.2025.06.002","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T02:16:14Z","timestamp":1749435374000},"page":"153-157","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Can probiotic-rich yogurt help prevent colorectal cancer in humans?"],"prefix":"10.1016","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1646-7741","authenticated-orcid":false,"given":"Biplab","family":"Adhikari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cpt.2025.06.002_bib1","doi-asserted-by":"crossref","DOI":"10.1177\/10732748241263650","article-title":"Microbiome dysbiosis, dietary intake and lifestyle-associated factors involve in epigenetic modulations in colorectal cancer: a narrative review","volume":"31","author":"Kwao-Zigah","year":"2024","journal-title":"Cancer Control"},{"key":"10.1016\/j.cpt.2025.06.002_bib2","series-title":"StatPearls [Internet]","article-title":"Rectal cancer","author":"Lotfollahzadeh","year":"2023"},{"key":"10.1016\/j.cpt.2025.06.002_bib3","doi-asserted-by":"crossref","first-page":"PR009","DOI":"10.1158\/1538-7755.DISP24-PR009","article-title":"Gut microbiome differences across race, ethnicity, and area level deprivation among patients undergoing colorectal cancer screening in Federally Qualified Health Centers","volume":"33","author":"Hogue","year":"2024","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.cpt.2025.06.002_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/3535982","article-title":"The role of probiotics in colorectal cancer management","volume":"2020","author":"Sivamaruthi","year":"2020","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.cpt.2025.06.002_bib5","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1038\/s41586-024-07754-w","article-title":"Gut microbiota carcinogen metabolism causes distal tissue tumours","volume":"632","author":"Roje","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.cpt.2025.06.002_bib6","series-title":"Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science","author":"Inamura","year":"2022"},{"key":"10.1016\/j.cpt.2025.06.002_bib7","doi-asserted-by":"crossref","first-page":"3962","DOI":"10.62347\/MYZA2640","article-title":"Fusobacterium nucleatum: a novel regulator of antitumor immune checkpoint blockade therapy in colorectal cancer","volume":"14","author":"Luo","year":"2024","journal-title":"Am J Cancer Res"},{"key":"10.1016\/j.cpt.2025.06.002_bib8","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2025.2452237","article-title":"Long-term yogurt intake and colorectal cancer incidence subclassified by Bifidobacterium abundance in tumor","volume":"17","author":"Ugai","year":"2025","journal-title":"Gut Microbes"},{"key":"10.1016\/j.cpt.2025.06.002_bib9","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.copbio.2016.11.010","article-title":"Health benefits of fermented foods: microbiota and beyond","volume":"44","author":"Marco","year":"2017","journal-title":"Curr Opin Biotechnol"},{"key":"10.1016\/j.cpt.2025.06.002_bib10","article-title":"Fermented dairy food intake and risk of colorectal cancer: a systematic review and meta-analysis","volume":"12","author":"Liang","year":"2022","journal-title":"Front Oncol"},{"key":"10.1016\/j.cpt.2025.06.002_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2021.789006","article-title":"Higher yogurt consumption is associated with lower risk of colorectal cancer: a systematic review and meta-analysis of observational studies","volume":"8","author":"Sun","year":"2022","journal-title":"Front Nutr"},{"key":"10.1016\/j.cpt.2025.06.002_bib12","doi-asserted-by":"crossref","first-page":"S190","DOI":"10.1093\/advances\/nmy114","article-title":"Association between dairy product consumption and colorectal cancer risk in adults: a systematic review and meta-analysis of epidemiologic studies","volume":"10","author":"Barrub\u00e9s","year":"2019","journal-title":"Adv Nutr"},{"key":"10.1016\/j.cpt.2025.06.002_bib13","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1158\/1055-9965.EPI-20-0127","article-title":"Dairy consumption and risks of colorectal cancer incidence and mortality: a meta-analysis of prospective cohort studies","volume":"29","author":"Jin","year":"2020","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.cpt.2025.06.002_bib14","article-title":"Gochujang suppresses cell survival and changes reactive oxygen species metabolism in colorectal cancer cells","volume":"68","author":"Seo","year":"2024","journal-title":"Food Nutr Res, Suppl"},{"key":"10.1016\/j.cpt.2025.06.002_bib15","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1097\/MS9.0000000000002030","article-title":"Effects of Lactococcus lactis on colorectal cancer in various terms: a narrative review","volume":"86","author":"Rivai","year":"2024","journal-title":"Ann Med Surg"},{"key":"10.1016\/j.cpt.2025.06.002_bib16","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00189-23","article-title":"The efficacy of prevention for colon cancer based on the microbiota therapy and the antitumor mechanisms with intervention of dietary Lactobacillus","volume":"11","author":"Xu","year":"2023","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.cpt.2025.06.002_bib17","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/cac2.12469","article-title":"Bifidobacterium adolescentis orchestrates CD143+ cancer-associated fibroblasts to suppress colorectal tumorigenesis by Wnt signaling-regulated GAS1","volume":"43","author":"Chen","year":"2023","journal-title":"Cancer Commun"},{"key":"10.1016\/j.cpt.2025.06.002_bib18","article-title":"Yogurt prevents colitis-associated colorectal cancer in mice","volume":"67","author":"Li","year":"2023","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.cpt.2025.06.002_bib19","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202403587","article-title":"5-Fluorouracil loaded prebiotic-probiotic liposomes modulating gut microbiota for improving colorectal cancer chemotherapy","volume":"14","author":"Sun","year":"2025","journal-title":"Adv Healthcare Mater"},{"key":"10.1016\/j.cpt.2025.06.002_bib20","doi-asserted-by":"crossref","first-page":"617","DOI":"10.11622\/smedj.2021104","article-title":"Is it time to lower the colorectal cancer screening age in average-risk adults in Singapore?","volume":"62","author":"Ang","year":"2021","journal-title":"Singap Med J"}],"container-title":["Cancer Pathogenesis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2949713225000576?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2949713225000576?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T16:22:46Z","timestamp":1773505366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2949713225000576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S2949713225000576"],"URL":"https:\/\/doi.org\/10.1016\/j.cpt.2025.06.002","relation":{},"ISSN":["2949-7132"],"issn-type":[{"value":"2949-7132","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Can probiotic-rich yogurt help prevent colorectal cancer in humans?","name":"articletitle","label":"Article Title"},{"value":"Cancer Pathogenesis and Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cpt.2025.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V. on behalf of Chinese Medical Association (CMA).","name":"copyright","label":"Copyright"}]}}