{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:59:22Z","timestamp":1761058762924,"version":"3.44.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalradiologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Radiology"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1016\/j.crad.2007.10.017","type":"journal-article","created":{"date-parts":[[2008,1,30]],"date-time":"2008-01-30T09:46:38Z","timestamp":1201686398000},"page":"636-641","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Successful intra-arterial alteplase infusion is a predictor of 12-month limb survival in patients with lower limb arterial occlusion"],"prefix":"10.1016","volume":"63","author":[{"given":"L.","family":"Disini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.F.","family":"Cockburn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.crad.2007.10.017_bib1","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1056\/NEJM199804163381603","article-title":"A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs. Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators","volume":"338","author":"Ouriel","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.crad.2007.10.017_bib2","doi-asserted-by":"crossref","first-page":"S337","DOI":"10.1016\/S1051-0443(07)61244-5","article-title":"Thrombolysis in the management of lower limb peripheral arterial occlusion\u2014a consensus document","volume":"14","author":"Working Party on Thrombolysis in the Management of Limb I","year":"2003","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.crad.2007.10.017_bib3","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0741-5214(96)70067-8","article-title":"Surgical revascularization versus thrombolysis for nonembolic lower extremity native artery occlusions: results of a prospective randomized trial. The STILE Investigators. Surgery versus thrombolysis for ischemia of the lower extremity","volume":"24","author":"Weaver","year":"1996","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.crad.2007.10.017_bib4","doi-asserted-by":"crossref","first-page":"249","DOI":"10.2174\/1568006043336113","article-title":"Thrombolytic therapy in peripheral arterial disease","volume":"4","author":"Giannini","year":"2004","journal-title":"Curr Drug Targets Cardiovasc Haematol Disord"},{"key":"10.1016\/j.crad.2007.10.017_bib5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1053\/ejvs.1999.0975","article-title":"A systematic review of intra-arterial thrombolytic therapy for lower-limb ischaemia","volume":"19","author":"Palfreyman","year":"2000","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.crad.2007.10.017_bib6","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/S0741-5214(94)70214-4","article-title":"A comparison of thrombolytic therapy with operative revascularization in the initial treatment of acute peripheral arterial ischemia","volume":"19","author":"Ouriel","year":"1994","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.crad.2007.10.017_bib7","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1583\/04-1226.1","article-title":"Safety of thrombolytic therapy with urokinase or recombinant tissue plasminogen activator for peripheral arterial occlusion: a comprehensive compilation of published work","volume":"11","author":"Ouriel","year":"2004","journal-title":"J Endovasc Ther"},{"key":"10.1016\/j.crad.2007.10.017_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1051-0443(96)70734-0","article-title":"Assessment of peripheral intraarterial thrombolysis versus surgical revascularization in acute lower-limb ischemia: a review of limb-salvage and mortality statistics","volume":"7","author":"Diffin","year":"1996","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.crad.2007.10.017_bib9","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.jvs.2004.01.019","article-title":"National Audit of Thrombolysis for Acute Leg Ischemia (NATALI): clinical factors associated with early outcome","volume":"39","author":"Earnshaw","year":"2004","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.crad.2007.10.017_bib10","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/s10016-005-8047-2","article-title":"Safety and efficacy of reteplase for the treatment of acute arterial occlusion: complexity of underlying lesion predicts outcome","volume":"19","author":"Hanover","year":"2005","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.crad.2007.10.017_bib11","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0741-5214(05)80036-9","article-title":"Thrombolysis or peripheral arterial surgery: phase I results. TOPAS Investigators","volume":"23","author":"Ouriel","year":"1996","journal-title":"J Vasc Surg"},{"year":"2005","series-title":"The encyclopaedic companion to medical statistics","author":"Everitt","key":"10.1016\/j.crad.2007.10.017_bib12"},{"key":"10.1016\/j.crad.2007.10.017_bib13","first-page":"148","article-title":"Acute limb ischemia","volume":"12","author":"Dormandy","year":"1999","journal-title":"Semin Vasc Surg"},{"key":"10.1016\/j.crad.2007.10.017_bib14","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S1051-0443(07)61372-4","article-title":"Evolving strategies for thrombolytic therapy of peripheral vascular occlusion","volume":"11","author":"Valji","year":"2000","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.crad.2007.10.017_bib15","series-title":"Endovascular intervention: current controversies","first-page":"179","article-title":"Thrombolysis for acute leg ischaemia: 20 years and out?","author":"Earnshaw","year":"2004"}],"container-title":["Clinical Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926007004874?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926007004874?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T16:18:57Z","timestamp":1757866737000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009926007004874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["S0009926007004874"],"URL":"https:\/\/doi.org\/10.1016\/j.crad.2007.10.017","relation":{},"ISSN":["0009-9260"],"issn-type":[{"type":"print","value":"0009-9260"}],"subject":[],"published":{"date-parts":[[2008,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Successful intra-arterial alteplase infusion is a predictor of 12-month limb survival in patients with lower limb arterial occlusion","name":"articletitle","label":"Article Title"},{"value":"Clinical Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crad.2007.10.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}