{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:02:59Z","timestamp":1758052979647,"version":"3.44.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalradiologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Radiology"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.crad.2012.09.010","type":"journal-article","created":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T16:49:36Z","timestamp":1354380576000},"page":"449-454","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["CT pulmonary angiography in elderly patients: Outcomes in patients aged >85 years"],"prefix":"10.1016","volume":"68","author":[{"given":"M.J.","family":"Laugharne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Paravasthu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Preston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.O.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.crad.2012.09.010_bib1","unstructured":"Hospital episode statistics: NHS Information Centre. Available at: http:\/\/www.hesonline.nhs.uk\/Ease\/ContentServer?siteID=1937&categoryID=214. [accessed 24.01.12]."},{"key":"10.1016\/j.crad.2012.09.010_bib2","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1148\/radiol.2421060971","article-title":"Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators","volume":"242","author":"Stein","year":"2007","journal-title":"Radiology"},{"key":"10.1016\/j.crad.2012.09.010_bib3","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1111\/j.1538-7836.2006.01918.x","article-title":"Accuracy of clinical decision rule, D-dimer and spiral computed tomography in patients with malignancy, previous venous thromboembolism, COPD or heart failure and in older patients with suspected pulmonary embolism","volume":"4","author":"Sohne","year":"2006","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.crad.2012.09.010_bib4","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1160\/TH08-04-0255","article-title":"Venous thromboembolism in the elderly: a community-based perspective","volume":"100","author":"Spencer","year":"2008","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.crad.2012.09.010_bib5","unstructured":"Payment by results draft guidance for 2012-13: Department of Health. Available at: http:\/\/www.dh.gov.uk\/prod_consum_dh\/groups\/dh_digitalassets\/documents\/digitalasset\/dh_132111.pdf. [accessed 24.01.12]."},{"key":"10.1016\/j.crad.2012.09.010_bib6","unstructured":"CQUIN, Department of Health. Available at: http:\/\/www.dh.gov.uk\/prod_consum_dh\/groups\/dh_digitalassets\/@dh\/@en\/@ps\/documents\/digitalasset\/dh_123009.pdf. [accessed 24.01.12]."},{"key":"10.1016\/j.crad.2012.09.010_bib7","unstructured":"Quality, innovation, productivity and prevention: Department of Health. Available at: http:\/\/www.dh.gov.uk\/en\/Healthcare\/Qualityandproductivity\/QIPPworkstreams\/DH_115447. [accessed 24.01.12]."},{"key":"10.1016\/j.crad.2012.09.010_bib8","unstructured":"Office for National Statistics licensed under the Open Government Licence v.1.0. Available at: http:\/\/www.ons.gov.uk\/ons\/publications\/re-reference-tables.html?edition=tcm%3A77-229866. [accessed 24.01.12]."},{"key":"10.1016\/j.crad.2012.09.010_bib9","doi-asserted-by":"crossref","first-page":"629","DOI":"10.2147\/VHRM.S2605","article-title":"Pulmonary embolism in the elderly: a review on clinical, instrumental and laboratory presentation","volume":"4","author":"Masotti","year":"2008","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.crad.2012.09.010_bib10","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1111\/j.1532-5415.2005.53309.x","article-title":"The challenge of diagnosing pulmonary embolism in elderly patients: influence of age on commonly used diagnostic tests and strategies","volume":"53","author":"Righini","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.crad.2012.09.010_bib11","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1111\/j.1445-5994.2007.01388.x","article-title":"D-dimer concentration increases with age reducing the clinical value of the D-dimer assay in the elderly","volume":"37","author":"Harper","year":"2007","journal-title":"Intern Med J"},{"key":"10.1016\/j.crad.2012.09.010_bib12","first-page":"1046","article-title":"Venous thromboembolism in very elderly patients: findings from a prospective registry (RIETE)","volume":"91","author":"L\u00f3pez-Jim\u00e9nez","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.crad.2012.09.010_bib13","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1001\/jama.293.16.2012","article-title":"Clinical validity of a negative computed tomography scan in patients with suspected pulmonary embolism: a systematic review","volume":"293","author":"Quiroz","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.crad.2012.09.010_bib14","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1001\/jama.298.23.2743","article-title":"Computed tomographic pulmonary angiography vs ventilation\u2013perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial","volume":"298","author":"Anderson","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.crad.2012.09.010_bib15","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1136\/thx.2005.040873","article-title":"Computed tomographic pulmonary angiography and prognostic significance in patients with acute pulmonary embolism","volume":"60","author":"Ghuysen","year":"2005","journal-title":"Thorax"},{"key":"10.1016\/j.crad.2012.09.010_bib16","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1148\/rg.261055062","article-title":"Can CT pulmonary angiography allow assessment of severity and prognosis in patients presenting with pulmonary embolism? What the radiologist needs to know","volume":"26","author":"Ghaye","year":"2006","journal-title":"Radiographics"},{"key":"10.1016\/j.crad.2012.09.010_bib17","unstructured":"EPA Radiogenic Cancer Risk Models and Projections for the U.S. Population (EPA 402-R-11-001), April 2011. p. 53. Available at: http:\/\/www.epa.gov\/radiation\/docs\/bluebook\/bbfinalversion.pdf. [accessed 24.01.12]."},{"key":"10.1016\/j.crad.2012.09.010_bib18","series-title":"Grainger and Allison's diagnostic radiology: a textbook of medical imaging","first-page":"34","article-title":"Intravascular contrast media for radiology, CT and MRI","author":"Grainger","year":"2008"},{"key":"10.1016\/j.crad.2012.09.010_bib19","doi-asserted-by":"crossref","first-page":"5K","DOI":"10.1016\/j.amjcard.2006.01.019","article-title":"Epidemiology and prognostic\u00a0implications of contrast-induced nephropathy","volume":"98","author":"McCullough","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.crad.2012.09.010_bib20","doi-asserted-by":"crossref","first-page":"376","DOI":"10.2214\/AJR.07.3280","article-title":"Frequency of serum creatinine changes in the absence of iodinated contrast material: implications for studies of contrast nephrotoxicity","volume":"191","author":"Newhouse","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.crad.2012.09.010_bib21","doi-asserted-by":"crossref","first-page":"494","DOI":"10.2214\/AJR.08.1908","article-title":"Probability of reduced renal function after contrast-enhanced CT: a model based on serum creatinine level, patient age, and estimated glomerular filtration rate","volume":"193","author":"Herts","year":"2009","journal-title":"AJR Am J Roentgenol"},{"issue":"Suppl. 1","key":"10.1016\/j.crad.2012.09.010_bib22","doi-asserted-by":"crossref","first-page":"i11","DOI":"10.1093\/ndt\/gfl215","article-title":"Contrast-induced nephropathy-prevention and risk reduction","volume":"21","author":"Lameire","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.crad.2012.09.010_bib23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/nrneph.2009.234","article-title":"Hospital-acquired acute kidney injury in the elderly","volume":"6","author":"Chronopoulos","year":"2010","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.crad.2012.09.010_bib24","doi-asserted-by":"crossref","first-page":"263","DOI":"10.2215\/CJN.03690907","article-title":"Contrast-induced nephropathy: what are the true clinical consequences?","volume":"3","author":"Rudnick","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.crad.2012.09.010_bib25","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group","volume":"130","author":"Levey","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.crad.2012.09.010_bib26","unstructured":"NICE Clinical Guideline CG73. National Collaborating Centre for Chronic Conditions. Chronic kidney disease: national clinical guideline for early identification and management in adults in primary and secondary care London: Royal College of Physicians, September 2008. Available at: http:\/\/www.nice.org.uk\/CG073fullguideline. [accessed 25.01.12]."},{"key":"10.1016\/j.crad.2012.09.010_bib27","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1136\/thorax.58.6.463","article-title":"Pulmonary embolism guidelines: will they work?","volume":"58","author":"Miller","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.crad.2012.09.010_bib28","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1056\/NEJMoa052367","article-title":"Multidetector computed tomography for acute pulmonary embolism","volume":"354","author":"Stein","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.crad.2012.09.010_bib29","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1148\/radiol.2481071528","article-title":"Identifying outpatients with renal insufficiency before contrast-enhanced CT by using estimated glomerular filtration rates versus serum creatinine levels","volume":"248","author":"Herts","year":"2008","journal-title":"Radiology"},{"key":"10.1016\/j.crad.2012.09.010_bib30","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1538-7836.2006.02251.x","article-title":"Contrast nephropathy following computed tomography angiography of the chest for pulmonary embolism in the emergency department","volume":"5","author":"Mitchell","year":"2007","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.crad.2012.09.010_bib31","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1538-7836.2009.03698.x","article-title":"Incidence and predictors of contrast induced nephropathy following CT-angiography for clinically suspected acute pulmonary embolism","volume":"8","author":"Kooiman","year":"2010","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.crad.2012.09.010_bib32","doi-asserted-by":"crossref","first-page":"170","DOI":"10.4065\/84.2.170","article-title":"Contrast-induced acute kidney injury: specialty-specific protocols for interventional radiology, diagnostic computed tomography radiology, and interventional cardiology","volume":"84","author":"Goldfarb","year":"2009","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.crad.2012.09.010_bib33","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1001\/archinte.168.12.1325","article-title":"Prevention, incidence, and outcomes of contrast-induced acute kidney injury","volume":"168","author":"Weisbord","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.crad.2012.09.010_bib34","doi-asserted-by":"crossref","first-page":"817","DOI":"10.3174\/ajnr.A1927","article-title":"Functional contrast-enhanced CT for evaluation of acute ischemic stroke does not increase the risk of contrast-induced nephropathy","volume":"31","author":"Lima","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.crad.2012.09.010_bib35","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.4065\/83.10.1095","article-title":"Mortality associated with nephropathy after radiographic contrast exposure","volume":"83","author":"From","year":"2008","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.crad.2012.09.010_bib36","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.2215\/CJN.00550109","article-title":"Contrast-induced nephropathy and long-term adverse events: cause and effect?","volume":"4","author":"Solomon","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.crad.2012.09.010_bib37","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ageing\/afg098","article-title":"Pulmonary embolism: differences in presentation between older and younger patients","volume":"32","author":"Timmons","year":"2003","journal-title":"Age Ageing"}],"container-title":["Clinical Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926012005193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926012005193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T16:25:35Z","timestamp":1757867135000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009926012005193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0009926012005193"],"URL":"https:\/\/doi.org\/10.1016\/j.crad.2012.09.010","relation":{},"ISSN":["0009-9260"],"issn-type":[{"type":"print","value":"0009-9260"}],"subject":[],"published":{"date-parts":[[2013,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CT pulmonary angiography in elderly patients: Outcomes in patients aged >85 years","name":"articletitle","label":"Article Title"},{"value":"Clinical Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crad.2012.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}