{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:04:09Z","timestamp":1758053049660,"version":"3.44.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["103-2420-H-002-006-MY2","104-2221-E-002-088","105-2314-B-002-094-MY3"],"award-info":[{"award-number":["103-2420-H-002-006-MY2","104-2221-E-002-088","105-2314-B-002-094-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalradiologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Radiology"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.crad.2017.12.006","type":"journal-article","created":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T09:36:06Z","timestamp":1515490566000},"page":"502.e9-502.e14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association between leukoaraiosis and cerebral blood flow territory alteration in asymptomatic internal carotid artery stenosis"],"prefix":"10.1016","volume":"73","author":[{"given":"Y.-F.","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.-S.","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.-C.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.-C.","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.-F.","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"23","key":"10.1016\/j.crad.2017.12.006_bib1","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1056\/NEJM200006083422302","article-title":"The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators","volume":"342","author":"Inzitari","year":"2000","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.crad.2017.12.006_bib2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1161\/STROKEAHA.113.003218","article-title":"Arterial spin labeling versus bolus-tracking perfusion in hyperacute stroke","volume":"45","author":"Bivard","year":"2014","journal-title":"Stroke"},{"issue":"6","key":"10.1016\/j.crad.2017.12.006_bib3","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1161\/STROKEAHA.114.005419","article-title":"Comparison of computed tomographic and magnetic resonance perfusion measurements in acute ischemic stroke: back-to-back quantitative analysis","volume":"45","author":"Lin","year":"2014","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.crad.2017.12.006_bib4","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/jcbfm.2009.204","article-title":"Arterial spin labeling perfusion MRI at multiple delay times: a correlative study with H(2)(15)O positron emission tomography in patients with symptomatic carotid artery occlusion","volume":"30","author":"Bokkers","year":"2010","journal-title":"J Cereb Blood Flow Metab"},{"issue":"8","key":"10.1016\/j.crad.2017.12.006_bib5","first-page":"1342","article-title":"Hemodynamic modifications in patients with symptomatic unilateral stenosis of the internal carotid artery: evaluation with MRI perfusion sequences","volume":"23","author":"Bozzao","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"issue":"2","key":"10.1016\/j.crad.2017.12.006_bib6","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/01616412.1990.11739923","article-title":"Compensatory mechanisms in patients with asymptomatic carotid artery occlusion","volume":"12","author":"Kuwert","year":"1990","journal-title":"Neurol Res"},{"issue":"4","key":"10.1016\/j.crad.2017.12.006_bib7","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1161\/01.STR.29.4.754","article-title":"Increased oxygen extraction fraction is associated with prior ischemic events in patients with carotid occlusion","volume":"29","author":"Derdeyn","year":"1998","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.crad.2017.12.006_bib8","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1148\/radiol.2462061775","article-title":"Brain perfusion territory imaging: methods and clinical applications of selective arterial spin-labeling MRI","volume":"246","author":"van Laar","year":"2008","journal-title":"Radiology"},{"issue":"2","key":"10.1016\/j.crad.2017.12.006_bib9","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1148\/radiol.2422060179","article-title":"Symptomatic carotid artery occlusion: flow territories of major brain-feeding arteries","volume":"242","author":"van Laar","year":"2007","journal-title":"Radiology"},{"issue":"11","key":"10.1016\/j.crad.2017.12.006_bib10","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1161\/STROKEAHA.108.515767","article-title":"Quantitative assessment of mixed cerebral vascular territory supply with vessel encoded arterial spin labeling MRI","volume":"39","author":"Kansagra","year":"2008","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.crad.2017.12.006_bib11","article-title":"Alterations of cerebral perfusion in asymptomatic internal carotid steno-occlusive disease","volume":"7","author":"Chen","year":"2017","journal-title":"Sci Rep"},{"issue":"20","key":"10.1016\/j.crad.2017.12.006_bib12","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects","volume":"310","author":"World Medical A","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.crad.2017.12.006_bib13","first-page":"37","article-title":"Pseudo-continuous flow driven adiabatic inversion for arterial spin labeling","volume":"13","author":"Garcia","year":"2005","journal-title":"Proc Int Soc Magn Reson Med"},{"issue":"5","key":"10.1016\/j.crad.2017.12.006_bib14","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/mrm.21403","article-title":"A theoretical and experimental investigation of the tagging efficiency of pseudocontinuous arterial spin labeling","volume":"58","author":"Wu","year":"2007","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.crad.2017.12.006_bib15","first-page":"295","article-title":"Mapping cerebral blood flow territories using harmonic encoding pseudocontinuous arterial spin labeling, fuzzy clustering, and independent component analysis","author":"Wu","year":"2011","journal-title":"Proc Int Soc Magn Reson Med"},{"issue":"3","key":"10.1016\/j.crad.2017.12.006_bib16","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1016\/j.neuroimage.2011.02.080","article-title":"Pseudocontinuous arterial spin labeling perfusion magnetic resonance imaging\u2014a normative study of reproducibility in the human brain","volume":"56","author":"Wu","year":"2011","journal-title":"Neuroimage"},{"issue":"9","key":"10.1016\/j.crad.2017.12.006_bib17","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1212\/WNL.43.9.1683","article-title":"Pathologic correlates of incidental\u00a0MRI white matter signal hyperintensities","volume":"43","author":"Fazekas","year":"1993","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.crad.2017.12.006_bib18","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"issue":"1","key":"10.1016\/j.crad.2017.12.006_bib19","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1148\/radiol.10091262","article-title":"Symptomatic carotid artery stenosis: impairment of cerebral autoregulation measured at the brain tissue level with arterial spin-labeling MRI","volume":"256","author":"Bokkers","year":"2010","journal-title":"Radiology"},{"issue":"4","key":"10.1016\/j.crad.2017.12.006_bib20","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.biopsych.2008.03.024","article-title":"Classification of white matter lesions on magnetic resonance imaging in elderly persons","volume":"64","author":"Kim","year":"2008","journal-title":"Biol Psychiatr"},{"issue":"5","key":"10.1016\/j.crad.2017.12.006_bib21","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1161\/STROKEAHA.107.501932","article-title":"Severity of leukoaraiosis and susceptibility to infarct growth in acute stroke","volume":"39","author":"Ay","year":"2008","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.crad.2017.12.006_bib22","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/01.wad.0000213815.20177.19","article-title":"Cognitive reserve and Alzheimer disease","volume":"20","author":"Stern","year":"2006","journal-title":"Alzheimer Dis Assoc Disord"},{"issue":"2","key":"10.1016\/j.crad.2017.12.006_bib23","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1161\/01.STR.0000049766.26453.E9","article-title":"Visual rating of age-related white matter changes on magnetic resonance imaging: scale comparison, interrater agreement, and correlations with quantitative measurements","volume":"34","author":"Kapeller","year":"2003","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.crad.2017.12.006_bib24","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1007\/s00415-004-0371-x","article-title":"White matter hyperintensities and rating scales - observer reliability varies with lesion load","volume":"251","author":"Wardlaw","year":"2004","journal-title":"J Neurol"}],"container-title":["Clinical Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926017305718?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926017305718?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T16:36:29Z","timestamp":1757867789000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009926017305718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["S0009926017305718"],"URL":"https:\/\/doi.org\/10.1016\/j.crad.2017.12.006","relation":{},"ISSN":["0009-9260"],"issn-type":[{"type":"print","value":"0009-9260"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between leukoaraiosis and cerebral blood flow territory alteration in asymptomatic internal carotid artery stenosis","name":"articletitle","label":"Article Title"},{"value":"Clinical Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crad.2017.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}