{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T17:23:28Z","timestamp":1783531408533,"version":"3.55.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalradiologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Radiology"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.crad.2019.11.016","type":"journal-article","created":{"date-parts":[[2019,12,28]],"date-time":"2019-12-28T07:40:48Z","timestamp":1577518848000},"page":"320.e1-320.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Role of sonoelastography in assessment of axillary lymph nodes in breast cancer: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"75","author":[{"given":"R.Y.","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.W.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.M.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.M.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.crad.2019.11.016_bib1","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.crad.2019.11.016_bib2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/tbj.12205","article-title":"Axillary lymph node status and prognosis in multifocal and multicentric breast carcinoma","volume":"20","author":"Duraker","year":"2014","journal-title":"Breast J"},{"key":"10.1016\/j.crad.2019.11.016_bib3","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.2217\/fon.13.154","article-title":"Lymph node ratio can further stratify prognosis in subpopulations of breast cancer patients with axillary nodal metastases","volume":"9","author":"Lawn","year":"2013","journal-title":"Future Oncol"},{"key":"10.1016\/j.crad.2019.11.016_bib4","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3390\/cancers2010020","article-title":"Number of axillary lymph node metastases determined by preoperative ultrasound is related to prognosis in patients with breast cancer","volume":"2","author":"Kijima","year":"2010","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.crad.2019.11.016_bib5","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.1016\/j.ejrad.2011.10.026","article-title":"Real-time elastography for the differentiation of benign and malignant superficial lymph nodes: a meta-analysis","volume":"81","author":"Ying","year":"2012","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.crad.2019.11.016_bib6","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1089\/lrb.2018.0012","article-title":"The role of elastography in diagnosis and staging of breast cancer-related lymphedema","volume":"17","author":"Erdogan Iyigun","year":"2019","journal-title":"Lymphat Res Biol"},{"key":"10.1016\/j.crad.2019.11.016_bib7","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.bjorl.2018.01.002","article-title":"Diagnostic role of ultrasound elastography on lymph node metastases in patients with head and neck cancer","volume":"85","author":"Pehlivan","year":"2019","journal-title":"Braz J Otorhinolaryngol"},{"key":"10.1016\/j.crad.2019.11.016_bib8","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1038\/s41598-017-02187-0","article-title":"Accuracy of shear wave elastography for the diagnosis of prostate cancer: a meta-analysis","volume":"7","author":"Sang","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.crad.2019.11.016_bib9","doi-asserted-by":"crossref","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","article-title":"QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies","volume":"155","author":"Whiting","year":"2011","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.crad.2019.11.016_bib10","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.jclinepi.2005.01.016","article-title":"The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed","volume":"58","author":"Deeks","year":"2005","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.crad.2019.11.016_bib11","doi-asserted-by":"crossref","first-page":"10234","DOI":"10.1038\/s41598-018-28474-y","article-title":"Application of real-time elastography ultrasound in the diagnosis of axillary lymph node metastasis in breast cancer patients","volume":"8","author":"Xu","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.crad.2019.11.016_bib12","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.ultrasmedbio.2012.12.013","article-title":"Sonographic elastography improves the sensitivity and specificity of axilla sampling in breast cancer: a prospective study","volume":"39","author":"Tsai","year":"2013","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.crad.2019.11.016_bib13","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.crad.2011.05.015","article-title":"Ultrasound elastography as an adjuvant to conventional ultrasound in the preoperative assessment of axillary lymph nodes in suspected breast cancer: a pilot study","volume":"66","author":"Taylor","year":"2011","journal-title":"Clin Radiol"},{"key":"10.1016\/j.crad.2019.11.016_bib14","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.2214\/AJR.13.12349","article-title":"Strain elastography of abnormal axillary nodes in breast cancer patients does not improve diagnostic accuracy compared with conventional ultrasound alone","volume":"203","author":"Park","year":"2014","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.crad.2019.11.016_bib15","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1002\/jum.14538","article-title":"Role of elastography in axillary examination of patients with breast cancer","volume":"37","author":"Chang","year":"2018","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.crad.2019.11.016_bib16","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/j.ultrasmedbio.2017.03.016","article-title":"Pre-operative evaluation of axillary lymph node status in patients with suspected breast cancer using shear wave elastography","volume":"43","author":"Youk","year":"2017","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.crad.2019.11.016_bib17","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1016\/j.ejrad.2012.04.031","article-title":"Elastography in the assessment of sentinel lymph nodes prior to dissection","volume":"81","author":"Tourasse","year":"2012","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.crad.2019.11.016_bib18","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.clinimag.2018.04.013","article-title":"Differentiation of benign and metastatic axillary lymph nodes in breast cancer: additive value of shear wave elastography to B-mode ultrasound","volume":"50","author":"Seo","year":"2018","journal-title":"Clin Imaging"},{"key":"10.1016\/j.crad.2019.11.016_bib19","doi-asserted-by":"crossref","first-page":"271","DOI":"10.7863\/ultra.15.03039","article-title":"Ex\u00a0vivo assessment of sentinel lymph nodes in breast cancer using shear wave elastography","volume":"35","author":"Kilic","year":"2016","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.crad.2019.11.016_bib20","doi-asserted-by":"crossref","first-page":"190","DOI":"10.4048\/jbc.2018.21.2.190","article-title":"Ex\u00a0vivo shear-wave elastography of axillary lymph nodes to predict nodal metastasis in patients with primary breast cancer","volume":"21","author":"Bae","year":"2018","journal-title":"J Breast Cancer"},{"key":"10.1016\/j.crad.2019.11.016_bib21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/jum.14663","article-title":"Association between shear wave elastography of virtual touch tissue imaging quantification parameters and the Ki-67 proliferation status in luminal-type breast cancer","volume":"38","author":"Liu","year":"2019","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.crad.2019.11.016_bib22","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s10549-013-2407-3","article-title":"Shear-wave elastography of invasive breast cancer: correlation between quantitative mean elasticity value and immunohistochemical profile","volume":"138","author":"Youk","year":"2013","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.crad.2019.11.016_bib23","doi-asserted-by":"crossref","first-page":"599","DOI":"10.3349\/ymj.2016.57.3.599","article-title":"Lymphangiogenesis in breast cancer correlates with matrix stiffness on shear-wave elastography","volume":"57","author":"Cha","year":"2016","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.crad.2019.11.016_bib24","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000002290","article-title":"Associations between elastography findings and clinicopathological factors in breast cancer","volume":"94","author":"Hayashi","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.crad.2019.11.016_bib25","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1148\/radiol.2391041676","article-title":"Breast disease: clinical application of US elastography for diagnosis","volume":"239","author":"Itoh","year":"2006","journal-title":"Radiology"},{"key":"10.1016\/j.crad.2019.11.016_bib26","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3233\/CH-16196","article-title":"Conventional US combined with acoustic radiation force impulse (ARFI) elastography for prediction of triple-negative breast cancer and the risk of lymphatic metastasis","volume":"65","author":"Pu","year":"2017","journal-title":"Clin Hemorheol Microcirc"},{"key":"10.1016\/j.crad.2019.11.016_bib27","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.euf.2015.06.003","article-title":"Transrectal ultrasound (US), contrast-enhanced US, real-time elastography, HistoScanning, magnetic resonance imaging (MRI), and MRI-US fusion biopsy in the diagnosis of prostate cancer","volume":"1","author":"Kuru","year":"2015","journal-title":"Eur Urol Focus"},{"key":"10.1016\/j.crad.2019.11.016_bib28","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1097\/SLA.0b013e3181f08f32","article-title":"Locoregional recurrence after sentinel lymph node dissection with or without axillary dissection in patients with sentinel lymph node metastases: the American College of Surgeons Oncology Group Z0011 randomized trial","volume":"252","author":"Giuliano","year":"2010","journal-title":"Ann Surg"},{"key":"10.1016\/j.crad.2019.11.016_bib29","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1016\/j.ultrasmedbio.2017.05.003","article-title":"Axillary lymph node sonographic features and breast tumor characteristics as predictors of malignancy: a nomogram to predict risk","volume":"43","author":"Akissue de Camargo Teixeira","year":"2017","journal-title":"Ultrasound Med Biol"},{"key":"10.1016\/j.crad.2019.11.016_bib30","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1002\/bjs.10920","article-title":"Meta-analysis of the diagnostic accuracy of ultrasound-guided fine-needle aspiration and core needle biopsy in diagnosing axillary lymph node metastasis","volume":"105","author":"Balasubramanian","year":"2018","journal-title":"Br J Surg"},{"key":"10.1016\/j.crad.2019.11.016_bib31","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/1759-7714.12774","article-title":"Axillary lymph node metastasis detection by magnetic resonance imaging in patients with breast cancer: a meta-analysis","volume":"9","author":"Zhou","year":"2018","journal-title":"Thorac Cancer"},{"key":"10.1016\/j.crad.2019.11.016_bib32","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.crad.2016.12.001","article-title":"MRI and FDG-PET\/CT based assessment of axillary lymph node metastasis in early breast cancer: a meta-analysis","volume":"72","author":"Liang","year":"2017","journal-title":"Clin Radiol"},{"key":"10.1016\/j.crad.2019.11.016_bib33","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1055\/s-0043-111589","article-title":"Prediction of pathological complete response to neoadjuvant chemotherapy for primary breast cancer comparing interim ultrasound, shear wave elastography and MRI","volume":"39","author":"Evans","year":"2018","journal-title":"Ultraschall Med"},{"key":"10.1016\/j.crad.2019.11.016_bib34","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10549-013-2747-z","article-title":"Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer?","volume":"143","author":"Evans","year":"2014","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.crad.2019.11.016_bib35","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1016\/j.ultrasmedbio.2018.07.017","article-title":"Pre-operative conventional ultrasound and sonoelastography evaluation for predicting axillary lymph node metastasis in patients with malignant breast lesions","volume":"44","author":"Zhao","year":"2018","journal-title":"Ultrasound Med Biol"}],"container-title":["Clinical Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926019306749?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926019306749?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T16:40:09Z","timestamp":1757868009000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009926019306749"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S0009926019306749"],"URL":"https:\/\/doi.org\/10.1016\/j.crad.2019.11.016","relation":{},"ISSN":["0009-9260"],"issn-type":[{"value":"0009-9260","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of sonoelastography in assessment of axillary lymph nodes in breast cancer: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Clinical Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crad.2019.11.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}