{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T08:23:00Z","timestamp":1778314980452,"version":"3.51.4"},"reference-count":39,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071988"],"award-info":[{"award-number":["82071988"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQ20F030018"],"award-info":[{"award-number":["LQ20F030018"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2019C03064"],"award-info":[{"award-number":["2019C03064"]}],"id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","award":["WKJ-ZJ-1926"],"award-info":[{"award-number":["WKJ-ZJ-1926"]}],"id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalradiologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Radiology"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.crad.2023.07.014","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T06:05:44Z","timestamp":1691042744000},"page":"e847-e855","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Multi-dimensional radiomics analysis to predict visceral pleural invasion in lung adenocarcinoma of \u22643 cm maximum diameter"],"prefix":"10.1016","volume":"78","author":[{"given":"S.","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Lou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.crad.2023.07.014_bib1","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"10.1016\/j.crad.2023.07.014_bib2","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.jtho.2018.10.002","article-title":"Demographics, safety and quality, and prognostic information in both the seventh and eighth editions of the TNM classification in 18,973 surgical cases of the Japanese joint committee of lung cancer registry database in 2010","volume":"14","author":"Okami","year":"2019","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.crad.2023.07.014_bib3","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.2147\/OTT.S100965","article-title":"The predictive and prognostic values of factors associated with visceral pleural involvement in resected lung adenocarcinomas","volume":"9","author":"Zhang","year":"2016","journal-title":"Onco Targets Ther"},{"issue":"2","key":"10.1016\/j.crad.2023.07.014_bib4","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/1759-7714.12412","article-title":"Effect of visceral pleural invasion on the prognosis of patients with lymph node negative non-small cell lung cancer","volume":"8","author":"Tian","year":"2017","journal-title":"Thorac Cancer"},{"key":"10.1016\/j.crad.2023.07.014_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.lungcan.2018.12.001","article-title":"Prognostic impact of microscopic vessel invasion and visceral pleural invasion and their correlations with epithelial\u2013mesenchymal transition, cancer stemness, and treatment failure in lung adenocarcinoma","volume":"128","author":"Neri","year":"2019","journal-title":"Lung Cancer"},{"issue":"4","key":"10.1016\/j.crad.2023.07.014_bib6","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.athoracsur.2016.09.052","article-title":"Recurrence pattern of pathologic stage I lung adenocarcinoma with visceral pleural invasion","volume":"103","author":"Jiwangga","year":"2017","journal-title":"Ann Thorac Surg"},{"issue":"11","key":"10.1016\/j.crad.2023.07.014_bib7","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1097\/JTO.0000000000000334","article-title":"The IASLC lung cancer staging project: the new database to inform the eighth edition of the TNM classification of lung cancer","volume":"9","author":"Rami-Porta","year":"2014","journal-title":"J Thorac Oncol"},{"issue":"2","key":"10.1016\/j.crad.2023.07.014_bib8","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/cam4.1990","article-title":"Impact of visceral pleural invasion on the association of extent of lymphadenectomy and survival in stage I non-small cell lung cancer","volume":"8","author":"Wo","year":"2019","journal-title":"Cancer Med"},{"issue":"3","key":"10.1016\/j.crad.2023.07.014_bib9","doi-asserted-by":"crossref","first-page":"592","DOI":"10.21037\/jtd.2019.12.121","article-title":"Sublobectomy versus lobectomy for long-term survival outcomes of early-stage non-small cell lung cancer with a tumour size \u22642 cm accompanied by visceral pleural invasion: a SEER population-based study","volume":"12","author":"Yu","year":"2020","journal-title":"J Thorac Dis"},{"issue":"42","key":"10.1016\/j.crad.2023.07.014_bib10","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000007323","article-title":"Convex border of peripheral non-small cell lung cancer on CT images as a potential indicator of pleural invasion","volume":"96","author":"Hsu","year":"2017","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"10.1016\/j.crad.2023.07.014_bib11","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1148\/radiol.2015151120","article-title":"Pleural tags on CT scans to predict visceral pleural invasion of non-small cell lung cancer that does not abut the pleura","volume":"279","author":"Hsu","year":"2016","journal-title":"Radiology"},{"issue":"12","key":"10.1016\/j.crad.2023.07.014_bib12","doi-asserted-by":"crossref","first-page":"9022","DOI":"10.1007\/s00330-021-07869-y","article-title":"Correlation between pleural tags on CT and visceral pleural invasion of peripheral lung cancer that does not appear touching the pleural surface","volume":"31","author":"Onoda","year":"2021","journal-title":"Eur Radiol"},{"issue":"5","key":"10.1016\/j.crad.2023.07.014_bib13","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1097\/RCT.0000000000000439","article-title":"Multivariate analysis of pleural invasion of peripheral non-small cell lung cancer-based computed tomography features","volume":"40","author":"Qi","year":"2016","journal-title":"J Comput Assist Tomogr"},{"issue":"16","key":"10.1016\/j.crad.2023.07.014_bib14","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.1158\/1078-0432.CCR-20-0020","article-title":"Radiomics, tumour volume, and blood biomarkers for early prediction of pseudoprogression in patients with metastatic melanoma treated with immune checkpoint inhibition","volume":"26","author":"Basler","year":"2020","journal-title":"Clin Cancer Res"},{"issue":"15","key":"10.1016\/j.crad.2023.07.014_bib15","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1158\/1078-0432.CCR-17-2507","article-title":"A new approach to predict progression-free survival in stage IV EGFR-mutant NSCLC patients with EGFR-TKI therapy","volume":"24","author":"Song","year":"2018","journal-title":"Clin Cancer Res"},{"issue":"13","key":"10.1016\/j.crad.2023.07.014_bib16","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.1158\/1078-0432.CCR-18-2861","article-title":"Radiomics on gadoxetic acid-enhanced magnetic resonance imaging for prediction of postoperative early and late recurrence of single hepatocellular carcinoma","volume":"25","author":"Kim","year":"2019","journal-title":"Clin Cancer Res"},{"issue":"5","key":"10.1016\/j.crad.2023.07.014_bib17","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1148\/rg.2017170056","article-title":"CT Texture analysis: definitions, applications, biologic correlates, and challenges","volume":"37","author":"Lubner","year":"2017","journal-title":"RadioGraphics"},{"key":"10.1016\/j.crad.2023.07.014_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2020.109111","article-title":"2D and 3D texture analysis to predict lymphovascular invasion in lung adenocarcinoma","volume":"129","author":"Yang","year":"2020","journal-title":"Eur J Radiol"},{"issue":"6","key":"10.1016\/j.crad.2023.07.014_bib19","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.tranon.2017.08.007","article-title":"2D and 3D CT radiomics features prognostic performance comparison in non-small cell lung cancer","volume":"10","author":"Shen","year":"2017","journal-title":"Transl Oncol"},{"issue":"5","key":"10.1016\/j.crad.2023.07.014_bib20","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1007\/s00330-018-5770-y","article-title":"Development of a radiomics nomogram based on the 2D and 3D CT features to predict the survival of non-small cell lung cancer patients","volume":"29","author":"Yang","year":"2019","journal-title":"Eur Radiol"},{"issue":"1","key":"10.1016\/j.crad.2023.07.014_bib21","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1002\/jmri.26192","article-title":"Radiomics analysis of apparent diffusion coefficient in cervical cancer: a preliminary study on histological grade evaluation","volume":"49","author":"Liu","year":"2019","journal-title":"J Magn Reson Imaging"},{"issue":"11","key":"10.1016\/j.crad.2023.07.014_bib22","doi-asserted-by":"crossref","first-page":"4514","DOI":"10.1007\/s00330-018-5463-6","article-title":"Classifying brain metastases by their primary site of origin using a radiomics approach based on texture analysis: a feasibility study","volume":"28","author":"Ortiz-Ram\u00f3n","year":"2018","journal-title":"Eur Radiol"},{"issue":"7","key":"10.1016\/j.crad.2023.07.014_bib23","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1007\/s00261-015-0438-4","article-title":"CT textural analysis of hepatic metastatic colorectal cancer: pre-treatment tumour heterogeneity correlates with pathology and clinical outcomes","volume":"40","author":"Lubner","year":"2015","journal-title":"Abdom Imaging"},{"issue":"8","key":"10.1016\/j.crad.2023.07.014_bib24","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1097\/JTO.0b013e3181a85d5e","article-title":"Visceral pleura invasion impact on non-small cell lung cancer patient survival: its implications for the forthcoming TNM staging based on a large-scale nation-wide database","volume":"4","author":"Yoshida","year":"2009","journal-title":"J Thorac Oncol"},{"issue":"11","key":"10.1016\/j.crad.2023.07.014_bib25","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1097\/JTO.0b013e3181eedd9c","article-title":"Visceral pleural invasion classification in non-small cell lung cancer","volume":"5","author":"Kawase","year":"2010","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.crad.2023.07.014_bib26","doi-asserted-by":"crossref","first-page":"571","DOI":"10.3389\/fonc.2020.00571","article-title":"Stratification of patients with stage IB NSCLC based on the 8th edition of the American joint committee on cancer (AJCC) staging manual","volume":"10","author":"Wu","year":"2020","journal-title":"Front Oncol"},{"issue":"3","key":"10.1016\/j.crad.2023.07.014_bib27","doi-asserted-by":"crossref","DOI":"10.1148\/ryct.2019190071","article-title":"Visceral pleural invasion in pulmonary adenocarcinoma: differences in CT patterns between solid and subsolid cancers","volume":"1","author":"Heidinger","year":"2019","journal-title":"Radiol Cardiothorac Imaging"},{"issue":"9","key":"10.1016\/j.crad.2023.07.014_bib28","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1097\/JTO.0000000000000630","article-title":"The 2015 World Health Organization classification of lung tumours: impact of genetic, clinical and radiologic advances since the 2004 classification","volume":"10","author":"Travis","year":"2015","journal-title":"J Thorac Oncol"},{"issue":"3","key":"10.1016\/j.crad.2023.07.014_bib29","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.athoracsur.2021.07.075","article-title":"Radiomic values from high-grade subtypes to predict spread through air spaces in lung adenocarcinoma","volume":"114","author":"Chen","year":"2022","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.crad.2023.07.014_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.876264","article-title":"A nomogram combined radiomics and clinical features as imaging biomarkers for prediction of visceral pleural invasion in lung adenocarcinoma","volume":"12","author":"Zha","year":"2022","journal-title":"Front Oncol"},{"issue":"1","key":"10.1016\/j.crad.2023.07.014_bib31","doi-asserted-by":"crossref","first-page":"3519","DOI":"10.1038\/s41598-017-02425-5","article-title":"Associations between radiologist-defined semantic and automatically computed radiomic features in non-small cell lung cancer","volume":"7","author":"Yip","year":"2017","journal-title":"Sci Rep"},{"issue":"12","key":"10.1016\/j.crad.2023.07.014_bib32","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.crad.2004.07.008","article-title":"Texture analysis of medical images","volume":"59","author":"Castellano","year":"2004","journal-title":"Clin Radiol"},{"issue":"5","key":"10.1016\/j.crad.2023.07.014_bib33","doi-asserted-by":"crossref","first-page":"809","DOI":"10.3174\/ajnr.A2061","article-title":"Texture analysis: a review of neurologic MR imaging applications","volume":"31","author":"Kassner","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"issue":"6","key":"10.1016\/j.crad.2023.07.014_bib34","doi-asserted-by":"crossref","first-page":"5905","DOI":"10.1007\/s13277-014-1781-8","article-title":"Reevaluation of survival and prognostic factors in pathologic stage I lung adenocarcinoma by the new 2009 TNM classification","volume":"35","author":"Fan","year":"2014","journal-title":"Tumour Biol"},{"issue":"6","key":"10.1016\/j.crad.2023.07.014_bib35","doi-asserted-by":"crossref","first-page":"e141","DOI":"10.1016\/j.cllc.2015.05.007","article-title":"Semiquantitative computed tomography characteristics for lung adenocarcinoma and their association with lung cancer survival","volume":"16","author":"Wang","year":"2015","journal-title":"Clin Lung Cancer"},{"issue":"873","key":"10.1016\/j.crad.2023.07.014_bib36","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1259\/bjr.73.873.11064644","article-title":"Rapidly growing small peripheral lung cancers detected by screening CT: correlation between radiological appearance and pathological features","volume":"73","author":"Wang","year":"2000","journal-title":"Br J Radiol"},{"issue":"5","key":"10.1016\/j.crad.2023.07.014_bib37","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1164\/ajrccm\/145.5.1236","article-title":"NHLBI workshop summaries. Pleural cell biology in health and disease","volume":"145","author":"Antony","year":"1992","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.crad.2023.07.014_bib38","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13014-015-0343-6","article-title":"Impact of tumour attachment to the pleura measured by a pretreatment CT image on outcome of stage I NSCLC treated with stereotactic body radiotherapy","volume":"10","author":"Yamamoto","year":"2015","journal-title":"Radiat Oncol"},{"issue":"2","key":"10.1016\/j.crad.2023.07.014_bib39","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.lungcan.2011.11.012","article-title":"Carcinoembryonic antigen (CEA) as tumour marker in lung cancer","volume":"76","author":"Grunnet","year":"2012","journal-title":"Lung Cancer"}],"container-title":["Clinical Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926023003215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926023003215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T16:49:51Z","timestamp":1757868591000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009926023003215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":39,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S0009926023003215"],"URL":"https:\/\/doi.org\/10.1016\/j.crad.2023.07.014","relation":{},"ISSN":["0009-9260"],"issn-type":[{"value":"0009-9260","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multi-dimensional radiomics analysis to predict visceral pleural invasion in lung adenocarcinoma of \u22643 cm maximum diameter","name":"articletitle","label":"Article Title"},{"value":"Clinical Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crad.2023.07.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier Ltd on behalf of The Royal College of Radiologists.","name":"copyright","label":"Copyright"}]}}