{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:07:47Z","timestamp":1788829667670,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalradiologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Radiology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.crad.2026.107401","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T05:20:53Z","timestamp":1780118453000},"page":"107401","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Efficacy of saline tract sealing after CT-Guided lung biopsy: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3070-9304","authenticated-orcid":false,"given":"A.T.","family":"Kayaoglu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1173-3362","authenticated-orcid":false,"given":"J.M.","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6828-2376","authenticated-orcid":false,"given":"V.V.","family":"Varela Betancourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1701-4855","authenticated-orcid":false,"given":"L.H.","family":"Fuenmayor Mena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9712-3741","authenticated-orcid":false,"given":"P.K.","family":"Carpilovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2286-3948","authenticated-orcid":false,"given":"Davi","family":"Barbosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4655-2033","authenticated-orcid":false,"given":"A.K.","family":"Taneja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.crad.2026.107401_bib1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1055\/s-0033-1342952","article-title":"Percutaneous lung biopsy: technique, efficacy, and complications","volume":"30","author":"Winokur","year":"2013","journal-title":"Semin Intervent Radiol"},{"issue":"1108","key":"10.1016\/j.crad.2026.107401_bib2","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20190866","article-title":"Pneumothorax rates in CT-Guided lung biopsies: a comprehensive systematic review and meta-analysis of risk factors","volume":"93","author":"Huo","year":"2020","journal-title":"Br J Radiol"},{"issue":"1","key":"10.1016\/j.crad.2026.107401_bib3","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1186\/s13019-024-02781-0","article-title":"Efficacy of autologous blood patch injection for pneumothorax rate after CT-guided percutaneous transthoracic lung biopsy: a systematic review and meta-analysis","volume":"19","author":"Chen","year":"2024","journal-title":"J Cardiothorac Surg"},{"issue":"3","key":"10.1016\/j.crad.2026.107401_bib4","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1148\/radiology.184.3.1509068","article-title":"Pneumothorax after lung biopsy: prevention with transpleural placement of compressed collagen foam plugs","volume":"184","author":"Engeler","year":"1992","journal-title":"Radiology"},{"issue":"6","key":"10.1016\/j.crad.2026.107401_bib5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF00338304","article-title":"Fibrin glue for sealing the needle track after percutaneous lung biopsy: part I--Experimental study","volume":"18","author":"Petsas","year":"1995","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"1","key":"10.1016\/j.crad.2026.107401_bib6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/RTI.0000000000000247","article-title":"Efficacy of a dehydrated hydrogel plug to reduce complications associated with computed tomography-guided percutaneous transthoracic needle biopsy","volume":"32","author":"Grage","year":"2017","journal-title":"J Thorac Imaging"},{"issue":"2","key":"10.1016\/j.crad.2026.107401_bib7","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/1754-9485.13002","article-title":"Tract sealing with normal saline after percutaneous transthoracic lung biopsies","volume":"64","author":"Babu","year":"2020","journal-title":"J Med Imag Rad Onc"},{"issue":"6","key":"10.1016\/j.crad.2026.107401_bib8","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1007\/s00330-008-0872-6","article-title":"CT-guided lung biopsy: incidence of pneumothorax after instillation of NaCl into the biopsy track","volume":"18","author":"Billich","year":"2008","journal-title":"Eur Radiol"},{"issue":"5","key":"10.1016\/j.crad.2026.107401_bib9","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s00270-023-03648-y","article-title":"Pneumothorax incidence with normal saline instillation for sealing the needle track after computed tomography-guided percutaneous lung biopsy","volume":"47","author":"Bourgeais","year":"2024","journal-title":"Cardiovasc Intervent Radiol"},{"issue":"11","key":"10.1016\/j.crad.2026.107401_bib10","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.crad.2015.06.081","article-title":"Usefulness of normal saline for sealing the needle track after CT-guided lung biopsy","volume":"70","author":"Li","year":"2015","journal-title":"Clinical Radiol"},{"issue":"23","key":"10.1016\/j.crad.2026.107401_bib11","doi-asserted-by":"crossref","first-page":"3546","DOI":"10.3390\/diagnostics13233546","article-title":"Usefulness of saline sealing in preventing pneumothorax after CT-Guided biopsies of the lung","volume":"13","author":"Roman","year":"2023","journal-title":"Diagnostics"},{"issue":"6","key":"10.1016\/j.crad.2026.107401_bib12","doi-asserted-by":"crossref","first-page":"3701","DOI":"10.1016\/j.acra.2024.12.058","article-title":"Efficacy of tract embolization on reducing pneumothorax in CT-Guided transthoracic lung biopsies: comparison of saline and autologous blood patch","volume":"32","author":"Tangobay","year":"2025","journal-title":"Academic Radiol"},{"issue":"4","key":"10.1016\/j.crad.2026.107401_bib13","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1097\/RCT.0000000000001725","article-title":"Effect of saline sealing after CT-Guided lung biopsy on pneumothorax and hemoptysis","volume":"49","author":"Zhang","year":"2025","journal-title":"J ComputAssist Tomography"},{"issue":"8","key":"10.1016\/j.crad.2026.107401_bib14","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1007\/s00270-019-02196-8","article-title":"Post-biopsy manoeuvres to reduce pneumothorax incidence in CT-Guided transthoracic lung biopsies: a systematic review and meta-analysis","volume":"42","author":"Huo","year":"2019","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.crad.2026.107401_bib15","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"issue":"10","key":"10.1016\/j.crad.2026.107401_bib16","article-title":"Updated guidance for trusted systematic reviews: a new edition of the cochrane handbook for systematic reviews of interventions","volume":"10","author":"Cumpston","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.crad.2026.107401_bib17","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.crad.2026.107401_bib18","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"issue":"7650","key":"10.1016\/j.crad.2026.107401_bib19","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.crad.2026.107401_bib20","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1186\/s12890-024-03315-z","article-title":"Normal saline injection and rapid rollover; preventive effect on incidence of pneumothorax after CT-guided lung biopsy: a retrospective cohort study","volume":"24","author":"Satomura","year":"2024","journal-title":"BMC Pulm Med"},{"issue":"4","key":"10.1016\/j.crad.2026.107401_bib21","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.carj.2018.08.002","article-title":"Injection of saline into the biopsy tract and rapid patient rollover decreases pneumothorax size following computed tomography\u2013guided transthoracic needle biopsy","volume":"69","author":"Khorochkov","year":"2018","journal-title":"Can Assoc Radiol J."},{"issue":"1166","key":"10.1016\/j.crad.2026.107401_bib22","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/bjr\/tqae228","article-title":"Efficacy of needle tract embolization using gelfoam in reducing incidence of pneumothorax in CT-guided transthoracic lung biopsies: a systematic review and meta-analysis","volume":"98","author":"Singh","year":"2025","journal-title":"British J Radiol"},{"issue":"1","key":"10.1016\/j.crad.2026.107401_bib23","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s40001-024-01707-9","article-title":"Autologous blood patch intraparenchymal injection reduces the incidence of pneumothorax and the need for chest tube placement following CT-guided lung biopsy: a systematic review and meta-analysis","volume":"29","author":"Li","year":"2024","journal-title":"Eur J Med Res"},{"issue":"4","key":"10.1016\/j.crad.2026.107401_bib24","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/1754-9485.13646","article-title":"Post- CT -guided lung biopsy optimisation of the observation period by identifying patients at risk of delayed pneumothorax","volume":"68","author":"Tan","year":"2024","journal-title":"J Med Imag Rad Onc"},{"issue":"9","key":"10.1016\/j.crad.2026.107401_bib25","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.7863\/ultra.15.10029","article-title":"Ultrasound versus computed tomographic guidance for percutaneous biopsy of chest lesions","volume":"35","author":"Jarmakani","year":"2016","journal-title":"J Ultrasound Med"}],"container-title":["Clinical Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926026001777?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926026001777?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:26:07Z","timestamp":1788827167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009926026001777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":25,"alternative-id":["S0009926026001777"],"URL":"https:\/\/doi.org\/10.1016\/j.crad.2026.107401","relation":{},"ISSN":["0009-9260"],"issn-type":[{"value":"0009-9260","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of saline tract sealing after CT-Guided lung biopsy: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Clinical Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crad.2026.107401","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Royal College of Radiologists. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107401"}}