{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:47:36Z","timestamp":1792097256734,"version":"4.4.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences","doi-asserted-by":"publisher","award":["2021- I2M-1\\u2013003"],"award-info":[{"award-number":["2021- I2M-1\\u2013003"]}],"id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalradiologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Radiology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.crad.2026.107416","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T23:55:32Z","timestamp":1781826932000},"page":"107416","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Effect of cardiac myosin inhibitors on cardiac structure and myocardial fibrosis in obstructive hypertrophic cardiomyopathy: a meta-analysis of cardiac magnetic resonance outcomes"],"prefix":"10.1016","volume":"102","author":[{"given":"Y.","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.crad.2026.107416_bib1","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0000000000001250","article-title":"2024 AHA\/ACC\/AMSSM\/HRS\/PACES\/SCMR guideline for the management of hypertrophic cardiomyopathy: a report of the American heart association\/american college of cardiology joint committee on clinical practice guidelines","author":"Ommen","year":"2024","journal-title":"Circulation"},{"key":"10.1016\/j.crad.2026.107416_bib2","doi-asserted-by":"crossref","first-page":"4622","DOI":"10.1093\/eurheartj\/ehad637","article-title":"Mavacamten: a first-in-class myosin inhibitor for obstructive hypertrophic cardiomyopathy","volume":"44","author":"Braunwald","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.crad.2026.107416_bib3","article-title":"Aficamten-A second in class cardiac Myosin inhibitor for hypertrophic cardiomyopathy","author":"Patel","year":"2023","journal-title":"Cardiol Rev."},{"key":"10.1016\/j.crad.2026.107416_bib4","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0140-6736(20)31792-X","article-title":"Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"396","author":"Olivotto","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.crad.2026.107416_bib5","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1001\/jamacardio.2023.3030","article-title":"Effect of mavacamten on Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy: the EXPLORER-CN randomized clinical trial","volume":"8","author":"Tian","year":"2023","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.crad.2026.107416_bib6","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1056\/NEJMoa2401424","article-title":"Aficamten for symptomatic obstructive hypertrophic cardiomyopathy","volume":"390","author":"Maron","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.crad.2026.107416_bib7","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1016\/j.jacc.2020.03.064","article-title":"Evaluation of mavacamten in symptomatic patients with nonobstructive hypertrophic cardiomyopathy","volume":"75","author":"Ho","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.crad.2026.107416_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e17336","article-title":"Cardiac magnetic resonance of hypertrophic heart phenotype: a review","volume":"9","author":"Tore","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.crad.2026.107416_bib9","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3348\/kjr.2021.0815","article-title":"Differential diagnosis of thick myocardium according to histologic features revealed by multiparametric cardiac magnetic resonance imaging","volume":"23","author":"Cha","year":"2022","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.crad.2026.107416_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/jcm13030842","article-title":"Advances in multi-modality imaging in hypertrophic cardiomyopathy","volume":"13","author":"Goldie","year":"2024","journal-title":"J Clin Med"},{"key":"10.1016\/j.crad.2026.107416_bib11","article-title":"Updated guidance for trusted systematic reviews: a new edition of the cochrane handbook for systematic reviews of interventions","volume":"10","author":"Cumpston","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.crad.2026.107416_bib12","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.crad.2026.107416_bib13","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"10.1016\/j.crad.2026.107416_bib14","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1161\/CIRCULATIONAHA.120.052359","article-title":"Mavacamten favorably impacts cardiac structure in obstructive hypertrophic cardiomyopathy: EXPLORER-HCM cardiac magnetic resonance substudy analysis","volume":"143","author":"Saberi","year":"2021","journal-title":"Circulation"},{"key":"10.1016\/j.crad.2026.107416_bib15","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1016\/j.jacc.2024.08.015","article-title":"Effect of aficamten on cardiac structure and function in obstructive hypertrophic cardiomyopathy: SEQUOIA-HCM CMR substudy","volume":"84","author":"Masri","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.crad.2026.107416_bib16","article-title":"Effects of mavacamten on cardiac magnetic resonance features in Chinese patients with obstructive hypertrophic cardiomyopathy","author":"Tian","year":"2025","journal-title":"JACC: Asia"},{"key":"10.1016\/j.crad.2026.107416_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12175710","article-title":"Revisiting diagnosis and treatment of hypertrophic cardiomyopathy: current practice and novel perspectives","volume":"12","author":"Ottaviani","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.crad.2026.107416_bib18","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jchf.2023.04.018","article-title":"Cardiac myosin inhibitors for managing obstructive hypertrophic cardiomyopathy: JACC: heart failure state-of-the-art review","volume":"11","author":"Ostrominski","year":"2023","journal-title":"JACC Heart Fail"},{"key":"10.1016\/j.crad.2026.107416_bib19","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abo7622","article-title":"Mavacamten, a precision medicine for hypertrophic cardiomyopathy: from a motor protein to patients","volume":"9","author":"Nag","year":"2023","journal-title":"Sci Adv"},{"key":"10.1016\/j.crad.2026.107416_bib20","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1001\/jama.2024.13946","article-title":"Risk stratification in nonischemic dilated cardiomyopathy using CMR imaging: a systematic review and meta-analysis","volume":"332","author":"Eichhorn","year":"2024","journal-title":"JAMA"},{"key":"10.1016\/j.crad.2026.107416_bib21","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1093\/eurheartj\/ehad194","article-title":"2023 ESC Guidelines for the management of cardiomyopathies","volume":"44","author":"Arbelo","year":"2023","journal-title":"Eur Heart J"},{"key":"10.1016\/j.crad.2026.107416_bib22","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/j.jacc.2010.11.013","article-title":"Assessment of myocardial fibrosis with cardiovascular magnetic resonance","volume":"57","author":"Mewton","year":"2011","journal-title":"J Am Coll Cardiol"}],"container-title":["Clinical Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926026001923?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009926026001923?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:36:48Z","timestamp":1792096608000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009926026001923"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":22,"alternative-id":["S0009926026001923"],"URL":"https:\/\/doi.org\/10.1016\/j.crad.2026.107416","relation":{},"ISSN":["0009-9260"],"issn-type":[{"value":"0009-9260","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of cardiac myosin inhibitors on cardiac structure and myocardial fibrosis in obstructive hypertrophic cardiomyopathy: a meta-analysis of cardiac magnetic resonance outcomes","name":"articletitle","label":"Article Title"},{"value":"Clinical Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crad.2026.107416","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Ltd on behalf of The Royal College of Radiologists.","name":"copyright","label":"Copyright"}],"article-number":"107416"}}