{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:06:23Z","timestamp":1793192783555,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"vor","delay-in-days":109,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100020884","name":"National Agency for Research and Development","doi-asserted-by":"publisher","award":["FONDECYT\/Postdoctorado 3220441"],"award-info":[{"award-number":["FONDECYT\/Postdoctorado 3220441"]}],"id":[{"id":"10.13039\/501100020884","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005853","name":"University of Chile","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005853","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["85220046"],"award-info":[{"award-number":["85220046"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["3220441"],"award-info":[{"award-number":["3220441"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Research in Food Science"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.crfs.2026.101416","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T23:48:23Z","timestamp":1776815303000},"page":"101416","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Liposomal and chitosan-coated liposomal nanocarriers for grape seed proanthocyanidins: Integrated physicochemical, cellular, and rheological characterization"],"prefix":"10.1016","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4201-0250","authenticated-orcid":false,"given":"Johana","family":"L\u00f3pez-Polo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9614-2393","authenticated-orcid":false,"given":"Jaime","family":"Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Villasante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Opazo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayleen","family":"Hormaz\u00e1bal-Daber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Jorquera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2381-9073","authenticated-orcid":false,"given":"Pamela J.","family":"Urrutia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando A.","family":"Osorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn","family":"Fuentes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hern\u00e1n","family":"Speisky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5633-6908","authenticated-orcid":false,"given":"Cristian Pati\u00f1o","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5379-3814","authenticated-orcid":false,"given":"Jimena","family":"Cordero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan M.","family":"Ruso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4951-0701","authenticated-orcid":false,"given":"Felipe A.","family":"Oyarzun-Ampuero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.crfs.2026.101416_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2024.121926","article-title":"Chitosan interaction with stomach mucin layer to enhances gastric retention and mucoadhesive properties","volume":"333","author":"Ahmad","year":"2024","journal-title":"Carbohydr. Polym."},{"issue":"1","key":"10.1016\/j.crfs.2026.101416_bib3","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1080\/13102818.2022.2027816","article-title":"Antimicrobial activity of chitosan nanoparticles","volume":"35","author":"Al-Zahrani","year":"2021","journal-title":"Biotechnol. Biotechnol. Equip."},{"issue":"1","key":"10.1016\/j.crfs.2026.101416_bib4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1080\/87559129.2021.1906699","article-title":"Prospects for PAss from grape seed: extraction technologies and diverse bioactivity","volume":"39","author":"An","year":"2023","journal-title":"Food Rev. Int."},{"issue":"11","key":"10.1016\/j.crfs.2026.101416_bib5","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.3390\/coatings11111366","article-title":"Chitosan-based antimicrobial coating for improving postharvest shelf life of pineapple","volume":"11","author":"Basumatary","year":"2021","journal-title":"Coatings"},{"issue":"4","key":"10.1016\/j.crfs.2026.101416_bib6","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3390\/gels10040284","article-title":"Liposome\u2013hydrogel composites for controlled drug delivery applications","volume":"10","author":"Binaymotlagh","year":"2024","journal-title":"Gels"},{"issue":"13","key":"10.1016\/j.crfs.2026.101416_bib8","doi-asserted-by":"crossref","first-page":"5125","DOI":"10.3390\/molecules28135125","article-title":"Determination of the main phase transition temperature of phospholipids by oscillatory rheology","volume":"28","author":"Budai","year":"2023","journal-title":"Molecules"},{"issue":"16","key":"10.1016\/j.crfs.2026.101416_bib7","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.3390\/nano13162340","article-title":"Viscoelasticity of liposomal dispersions","volume":"13","author":"Budai","year":"2023","journal-title":"Nanomaterials"},{"key":"10.1016\/j.crfs.2026.101416_bib9","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ibneur.2023.11.007","article-title":"Superoxide dismutase and neurological disorders","volume":"16","author":"Chidambaram","year":"2024","journal-title":"IBRO Neuroscience Reports"},{"key":"10.1016\/j.crfs.2026.101416_bib10","article-title":"Oxidative stress and inflammation in the pathogenesis of neurological disorders: mechanisms and implications","author":"Dash","year":"2024","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.crfs.2026.101416_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2022.112737","article-title":"Liposomes containing nanoparticles: preparation and applications","volume":"218","author":"De Leo","year":"2022","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.crfs.2026.101416_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.cocis.2024.101875","article-title":"Liposomes: bridging the gap from lab to pharmaceuticals","volume":"75","author":"Eugster","year":"2025","journal-title":"Current opinion in colloid & interface science"},{"issue":"3","key":"10.1016\/j.crfs.2026.101416_bib14","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1529\/biophysj.105.064030","article-title":"Effect of ion-binding and chemical phospholipid structure on the nanomechanics of lipid bilayers studied by force spectroscopy","volume":"89","author":"Garcia-Manyes","year":"2005","journal-title":"Biophys. J."},{"key":"10.1016\/j.crfs.2026.101416_bib15","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1007\/s00217-014-2405-7","article-title":"Preparation of PEG-modified PAs liposome and its application in cosmetics","volume":"240","author":"Guo","year":"2015","journal-title":"European Food Research and Technology"},{"issue":"1","key":"10.1016\/j.crfs.2026.101416_bib16","article-title":"El extracto de proantocianidina de semilla de uva inhibe el da\u00f1o al ADN y a las prote\u00ednas y las actividades l\u00e1biles del hierro, las enzimas y las c\u00e9lulas cancerosas","volume":"12","author":"Habib","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.crfs.2026.101416_bib18","series-title":"Chitosan in Drug Delivery","first-page":"225","article-title":"Chitosan as mucoadhesive polymer in drug delivery","author":"Hasnain","year":"2022"},{"key":"10.1016\/j.crfs.2026.101416_bib19","article-title":"Ultrasonic-assisted nanoencapsulation of kiwi leaves PAss in liposome delivery system for enhanced biostability and bioavailability","volume":"416","author":"Ji-Min","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.crfs.2026.101416_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.fhfh.2023.100142","article-title":"Liposome mediated encapsulation and role of chitosan on modulating liposomal stability to deliver potential bioactives-A review","volume":"4","author":"Joy","year":"2023","journal-title":"Food Hydrocolloids for Health"},{"issue":"4","key":"10.1016\/j.crfs.2026.101416_bib21","doi-asserted-by":"crossref","DOI":"10.1002\/anbr.202200101","article-title":"Liposomes under shear: structure, dynamics, and drug delivery applications","volume":"3","author":"Karaz","year":"2023","journal-title":"Advanced nanobiomed research"},{"issue":"14","key":"10.1016\/j.crfs.2026.101416_bib22","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.3390\/plants11141809","article-title":"Insights into polyphenol\u2013lipid interactions: chemical methods, molecular aspects and their effects on membrane structures","volume":"11","author":"Karonen","year":"2022","journal-title":"Plants"},{"key":"10.1016\/j.crfs.2026.101416_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2021.113851","article-title":"Liposome composition in drug delivery design, synthesis, characterization, and clinical application","volume":"176","author":"Large","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"4","key":"10.1016\/j.crfs.2026.101416_bib24","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1021\/jf960282f","article-title":"Effect of drying temperature on the stability of polyphenols and antioxidant activity of red grape pomace peels","volume":"45","author":"Larrauri","year":"1997","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.crfs.2026.101416_bib25","series-title":"The Impact of Food Bioactives on Health: in Vitro and Ex Vivo Models","first-page":"103","article-title":"Caco-2 cell line","author":"Lea","year":"2015"},{"issue":"5","key":"10.1016\/j.crfs.2026.101416_bib26","doi-asserted-by":"crossref","first-page":"740","DOI":"10.3390\/foods13050740","article-title":"Encapsulaci\u00f3n y caracterizaci\u00f3n de microc\u00e1psulas de proantocianidina mediante alginato de sodio y carboximetilcelulosa","volume":"13","author":"Li","year":"2024","journal-title":"Foods"},{"key":"10.1016\/j.crfs.2026.101416_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.133230","article-title":"Stability enhancement of PAs-loaded liposomes via surface decoration with oxidized konjac glucomannan","volume":"275","author":"Lin","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"37","key":"10.1016\/j.crfs.2026.101416_bib28","doi-asserted-by":"crossref","first-page":"43414","DOI":"10.1021\/acsami.3c07854","article-title":"Regulation of nanoliposome rigidity and bioavailability of oligomeric PAs with phytosterols containing different C3 branches","volume":"15","author":"Liu","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.crfs.2026.101416_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2019.108967","article-title":"Effect of lyophilization on the physicochemical and rheological properties of food grade liposomes that encapsulate rutin","volume":"130","author":"Lopez-Polo","year":"2020","journal-title":"Food Res. Int."},{"key":"10.1016\/j.crfs.2026.101416_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2023.115583","article-title":"Effect of the incorporation of liposomes loaded with rutin on the transport properties of edible film produced with hydroxypropyl methylcellulose: an in vitro release study","volume":"191","author":"Lopez-Polo","year":"2024","journal-title":"LWT"},{"key":"10.1016\/j.crfs.2026.101416_bib32","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.neuro.2022.07.008","article-title":"The SH-SY5Y human neuroblastoma cell line, a relevant in vitro cell model for investigating neurotoxicology in human: focus on organic pollutants","volume":"92","author":"Lopez-Suarez","year":"2022","journal-title":"Neurotoxicology"},{"issue":"3","key":"10.1016\/j.crfs.2026.101416_bib33","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/aocs.12907","article-title":"Liposomes as sustainable delivery systems in food, cosmetic, and pharmaceutical applications","volume":"102","author":"Luo","year":"2025","journal-title":"J. Am. Oil Chem. Soc."},{"issue":"7","key":"10.1016\/j.crfs.2026.101416_bib35","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.3390\/antiox11071367","article-title":"Evaluation of proanthocyanidins from kiwi leaves (actinidia chinensis) against caco-2 cells oxidative stress through nrf2-ARE signaling pathway","volume":"11","author":"Lv","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.crfs.2026.101416_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.135794","article-title":"Ultrasonic-assisted nanoencapsulation of kiwi leaves PAss in liposome delivery system for enhanced biostability and bioavailability","volume":"416","author":"Lv","year":"2023","journal-title":"Food Chem."},{"issue":"3","key":"10.1016\/j.crfs.2026.101416_bib37","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/08982100902729436","article-title":"Chitosomes loaded with cranberry PAss attenuate the bacterial lipopolysaccharide-induced expression of iNOS and COX-2 in raw 264.7 macrophages","volume":"19","author":"Madrigal-Carballo","year":"2009","journal-title":"J. Liposome Res."},{"key":"10.1016\/j.crfs.2026.101416_bib38","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.tifs.2022.01.001","article-title":"Applications of chitosan-based carrier as an encapsulating agent in food industry","volume":"120","author":"Maleki","year":"2022","journal-title":"Trends Food Sci. Technol."},{"key":"10.1016\/j.crfs.2026.101416_bib39","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jfoodeng.2017.12.009","article-title":"Encapsulation of food waste compounds in soy phosphatidylcholine liposomes: effect of freeze-drying, storage stability and functional aptitude","volume":"223","author":"Mar\u00edn","year":"2018","journal-title":"J. Food Eng."},{"key":"10.1016\/j.crfs.2026.101416_bib40","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/BF00756522","article-title":"The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications","volume":"11","author":"Meunier","year":"1995","journal-title":"Cell biology and toxicology"},{"key":"10.1016\/j.crfs.2026.101416_bib41","article-title":"The rheology handbook: for users of rotational and oscillatory rheometers","author":"Mezger","year":"2020","journal-title":"European Coatings"},{"issue":"6","key":"10.1016\/j.crfs.2026.101416_bib42","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.3390\/nu12061623","article-title":"Proanthocyanidin-rich grape seed extract reduces inflammation and oxidative stress and restores tight junction barrier function in Caco-2 colon cells","volume":"12","author":"Nallathambi","year":"2020","journal-title":"Nutrients"},{"issue":"9","key":"10.1016\/j.crfs.2026.101416_bib44","doi-asserted-by":"crossref","first-page":"552","DOI":"10.3390\/nu8090552","article-title":"Anticancer efficacy of polyphenols and their combinations","volume":"8","author":"Niedzwiecki","year":"2016","journal-title":"Nutrients"},{"issue":"10","key":"10.1016\/j.crfs.2026.101416_bib45","doi-asserted-by":"crossref","DOI":"10.1002\/fsn3.71000","article-title":"Protective effects proanthocyanidin Nanoliposome freeze\u2010dried powder on oxidative injury in a p31\u201043 induced celiac disease cell model","volume":"13","author":"Ning","year":"2025","journal-title":"Food Sci. Nutr."},{"issue":"4","key":"10.1016\/j.crfs.2026.101416_bib46","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S1773-2247(10)50043-1","article-title":"Chitosan-coated lipid nanocarriers for therapeutic applications","volume":"20","author":"Oyarzun-Ampuero","year":"2010","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"3","key":"10.1016\/j.crfs.2026.101416_bib47","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1080\/17460441.2023.2293158","article-title":"The SH-SY5Y cell line: a valuable tool for Parkinson's disease drug discovery","volume":"19","author":"Pandey","year":"2024","journal-title":"Expet Opin. Drug Discov."},{"issue":"11","key":"10.1016\/j.crfs.2026.101416_bib48","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.3390\/antiox11112236","article-title":"Physical and oxidative water-in-oil emulsion stability by the addition of liposomes from shrimp waste oil with antioxidant and anti-inflammatory properties","volume":"11","author":"Pascual-Silva","year":"2022","journal-title":"Antioxidants"},{"issue":"18","key":"10.1016\/j.crfs.2026.101416_bib49","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1016\/j.phytochem.2005.03.025","article-title":"Occurrence and biological significance of PAss in the American diet","volume":"66","author":"Prior","year":"2005","journal-title":"Phytochemistry"},{"issue":"3","key":"10.1016\/j.crfs.2026.101416_bib50","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3390\/pr9030445","article-title":"Chitosan-coating effect on the characteristics of liposomes: a focus on bioactive compounds and essential oils: a review","volume":"9","author":"Sebaaly","year":"2021","journal-title":"Processes"},{"key":"10.1016\/j.crfs.2026.101416_bib51","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jfoodeng.2018.01.001","article-title":"Design of dipalmitoyl lecithin liposomes loaded with quercetin and rutin and their release kinetics from carboxymethyl cellulose edible films","volume":"224","author":"Silva-Weiss","year":"2018","journal-title":"J. Food Eng."},{"issue":"36","key":"10.1016\/j.crfs.2026.101416_bib52","doi-asserted-by":"crossref","first-page":"8851","DOI":"10.1021\/jf205167k","article-title":"First web-based database on total phenolics and oxygen radical absorbance capacity (ORAC) of fruits produced and consumed within the south Andes region of South America","volume":"60","author":"Speisky","year":"2012","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.crfs.2026.101416_bib53","series-title":"Rheological Methods in Food Process Engineering","author":"Steffe","year":"1996"},{"key":"10.1016\/j.crfs.2026.101416_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneumeth.2021.109301","article-title":"Long-term culture of SH-SY5Y neuroblastoma cells in the absence of neurotrophins: a novel model of neuronal ageing","volume":"362","author":"Strother","year":"2021","journal-title":"J. Neurosci. Methods"},{"issue":"4","key":"10.1016\/j.crfs.2026.101416_bib55","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1517\/17425255.4.4.395","article-title":"The Caco-2 cell monolayer: usefulness and limitations","volume":"4","author":"Sun","year":"2008","journal-title":"Expet Opin. Drug Metabol. Toxicol."},{"issue":"5","key":"10.1016\/j.crfs.2026.101416_bib56","article-title":"EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Safety of cranberry extract powder as a novel food ingredient pursuant to Regulation (EC) no 258\/97","volume":"15","author":"Turck","year":"2017","journal-title":"EFSA J."},{"key":"10.1016\/j.crfs.2026.101416_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2020.103861","article-title":"PAss in grape seeds: an updated review of their health benefits and potential uses in the food industry","volume":"67","author":"Unusan","year":"2020","journal-title":"J. Funct.Foods"},{"issue":"9","key":"10.1016\/j.crfs.2026.101416_bib58","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1016\/j.bbadis.2017.05.015","article-title":"Cell death induced by mitochondrial complex I inhibition is mediated by Iron Regulatory Protein 1","volume":"1863","author":"Urrutia","year":"2017","journal-title":"Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease"},{"issue":"12","key":"10.1016\/j.crfs.2026.101416_bib61","doi-asserted-by":"crossref","first-page":"5041","DOI":"10.1021\/jf058018m","article-title":"Antioxidant and membrane effects of procyanidin dimers and trimers isolated from peanut and cocoa","volume":"53","author":"Verstraeten","year":"2005","journal-title":"J. Agric. Food Chem."},{"issue":"11","key":"10.1016\/j.crfs.2026.101416_bib60","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1016\/j.bbamem.2013.07.023","article-title":"Procyanidins can interact with Caco-2 cell membrane lipid rafts: involvement of cholesterol","volume":"1828","author":"Verstraeten","year":"2013","journal-title":"Biochimica et Biophysica Acta (BBA)-Biomembranes"},{"key":"10.1016\/j.crfs.2026.101416_bib59","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jfoodeng.2018.07.033","article-title":"Effect of lyophilization on food grade liposomes loaded with conjugated linoleic acid","volume":"240","author":"V\u00e9lez","year":"2019","journal-title":"J. Food Eng."},{"issue":"12","key":"10.1016\/j.crfs.2026.101416_bib63","doi-asserted-by":"crossref","first-page":"4026","DOI":"10.1021\/jf049696w","article-title":"Lipophilic and hydrophilic antioxidant capacities of common foods in the United States","volume":"52","author":"Wu","year":"2004","journal-title":"J. Agric. Food Chem."},{"issue":"40","key":"10.1016\/j.crfs.2026.101416_bib64","doi-asserted-by":"crossref","first-page":"10457","DOI":"10.1039\/c2sm25668a","article-title":"A rheological study on temperature dependent microstructural changes of fumed silica gels in dodecane","volume":"8","author":"Wu","year":"2012","journal-title":"Soft Matter"},{"key":"10.1016\/j.crfs.2026.101416_bib65","article-title":"Emerging mechanistic insights into liposomal stability: full process management from production and storage to food application","author":"Xu","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.crfs.2026.101416_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.fbio.2024.104899","article-title":"Complex phospholipid liposomes co-encapsulated of PAss and \u03b1-tocopherol: stability, antioxidant activity and in vitro digestion simulation","volume":"61","author":"Zhao","year":"2024","journal-title":"Food Biosci."},{"key":"10.1016\/j.crfs.2026.101416_bib67","first-page":"407","article-title":"Effects of chitosan coating on physical properties and pharmacokinetic behavior of mitoxantrone liposomes","author":"Zhuang","year":"2010","journal-title":"International journal of nanomedicine"}],"container-title":["Current Research in Food Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665927126001164?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665927126001164?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:04:32Z","timestamp":1785816272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2665927126001164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":60,"alternative-id":["S2665927126001164"],"URL":"https:\/\/doi.org\/10.1016\/j.crfs.2026.101416","relation":{},"ISSN":["2665-9271"],"issn-type":[{"value":"2665-9271","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liposomal and chitosan-coated liposomal nanocarriers for grape seed proanthocyanidins: Integrated physicochemical, cellular, and rheological characterization","name":"articletitle","label":"Article Title"},{"value":"Current Research in Food Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crfs.2026.101416","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101416"}}