{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T20:41:41Z","timestamp":1794343301393,"version":"4.9.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":209,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100024370","name":"Ministero dell'Istruzione dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["H91I22000090007"],"award-info":[{"award-number":["H91I22000090007"]}],"id":[{"id":"10.13039\/501100024370","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Research in Food Science"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.crfs.2026.101519","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:04:46Z","timestamp":1785427486000},"page":"101519","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Linking antioxidant activity to strain-specific exometabolomic profiles in probiotic Lactobacillus paracasei and Lactobacillus plantarum fermentation supernatants"],"prefix":"10.1016","volume":"13","author":[{"given":"Marianna","family":"Ciaccia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4771-8912","authenticated-orcid":false,"given":"Matteo","family":"Radice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1361-1508","authenticated-orcid":false,"given":"Kristina","family":"Haslinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4430-2978","authenticated-orcid":false,"given":"Rosangela","family":"Limongelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennaro","family":"Agrimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0728-2226","authenticated-orcid":false,"given":"Isabella","family":"Pisano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"19","key":"10.1016\/j.crfs.2026.101519_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221910467","article-title":"Untargeted metabolic profiling of extracellular vesicles of sars-cov-2-infected patients shows presence of potent anti-inflammatory metabolites","volume":"22","author":"Alzahrani","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.crfs.2026.101519_bib2","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s00253-012-4241-7","article-title":"Antioxidant properties of potentially probiotic bacteria: in vitro and in vivo activities","volume":"97","author":"Amaretti","year":"2013","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"13","key":"10.1016\/j.crfs.2026.101519_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25133024","article-title":"Bacterial biotransformation of oleic acid: new findings on the formation of \u03b3-Dodecalactone and 10-Ketostearic acid in the culture of Micrococcus luteus","volume":"25","author":"Boratynski","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.crfs.2026.101519_bib4","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.phrs.2018.01.020","article-title":"Gut microbiota and probiotics intervention: a potential therapeutic target for management of cardiometabolic disorders and chronic kidney disease?","volume":"130","author":"Cavalcanti Neto","year":"2018","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.crfs.2026.101519_bib5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.phrs.2019.03.002","article-title":"Novel function of VEGF-B as an antioxidant and therapeutic implications","volume":"143","author":"Chen","year":"2019","journal-title":"Pharmacol. Res."},{"issue":"10","key":"10.1016\/j.crfs.2026.101519_bib6","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.4014\/jmb.2306.06014","article-title":"Bidirectional interactions between green tea (GT) polyphenols and human gut bacteria","volume":"33","author":"Choi","year":"2023","journal-title":"J. Microbiol. Biotechnol."},{"issue":"1","key":"10.1016\/j.crfs.2026.101519_bib7","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/s41598-020-57615-5","article-title":"Lactobacillus plantarum LMT1-48 exerts anti-obesity effect in high-fat diet-induced obese mice by regulating expression of lipogenic genes","volume":"10","author":"Choi","year":"2020","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.crfs.2026.101519_bib8","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s43393-022-00125-4","article-title":"Bioactive peptides in fermented foods and their application: a critical review","volume":"3","author":"Chourasia","year":"2023","journal-title":"Syst. Microbiol. Biomanuf."},{"key":"10.1016\/j.crfs.2026.101519_bib9","unstructured":"Compound Discoverer 3.2 \u2013 The Ultimate Toolbox to Analyze Untargeted Metabolomics Data | My Compound Discoverer. (n.d.). Retrieved from https:\/\/mycompounddiscoverer.com\/2020\/09\/23\/compound-discoverer-3-2-the-ultimate-toolbox-to-analyze-untargeted-metabolomics-data\/."},{"issue":"4","key":"10.1016\/j.crfs.2026.101519_bib10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s41592-019-0344-8","article-title":"Sirius 4: a rapid tool for turning tandem mass spectra into metabolite structure information","volume":"16","author":"D\u00fchrkop","year":"2019","journal-title":"Nat. Methods"},{"issue":"4","key":"10.1016\/j.crfs.2026.101519_bib11","first-page":"168","article-title":"The antioxidant activity of Lactic acid bacteria and probiotics: a review","volume":"6","author":"Faraki","year":"2020","journal-title":"Journal of Food Safety and Hygiene"},{"issue":"1","key":"10.1016\/j.crfs.2026.101519_bib12","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2020.1801944","article-title":"Oxidative stress tolerance and antioxidant capacity of lactic acid bacteria as probiotic: a systematic review","volume":"12","author":"Feng","year":"2020","journal-title":"Gut Microbes"},{"issue":"1","key":"10.1016\/j.crfs.2026.101519_bib13","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s00253-024-13384-z","article-title":"Integration of metabolomics and other omics: from microbes to microbiome","volume":"108","author":"Go","year":"2024","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"7","key":"10.1016\/j.crfs.2026.101519_bib14","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.3390\/molecules26071858","article-title":"Characteristics of the proteolytic enzymes produced by lactic acid bacteria","volume":"26","author":"Kieliszek","year":"2021","journal-title":"Molecules"},{"issue":"9","key":"10.1016\/j.crfs.2026.101519_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms9091971","article-title":"Antioxidant and anti-inflammatory effect and probiotic properties of lactic acid bacteria isolated from canine and feline feces","volume":"9","author":"Kim","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.crfs.2026.101519_bib16","series-title":"Foods","article-title":"A comprehensive overview of postbiotics with a special focus on discovery techniques and clinical applications","volume":"13","author":"Kumar","year":"2024"},{"issue":"1","key":"10.1016\/j.crfs.2026.101519_bib17","first-page":"1","article-title":"Short-chain fatty acids play a positive role in colorectal cancer","volume":"15","author":"Liu","year":"2024","journal-title":"Discov. Oncol."},{"issue":"3","key":"10.1016\/j.crfs.2026.101519_bib18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3390\/metabo7030043","article-title":"Extracellular microbial metabolomics: the state of the art","volume":"7","author":"Pinu","year":"2017","journal-title":"Metabolites"},{"issue":"2","key":"10.1016\/j.crfs.2026.101519_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.afres.2025.101260","article-title":"Bio-preservation effect of lactic acid bacteria postbiotics on physical, chemical, and sensory properties of vacuum-packaged broiler breast meat","volume":"5","author":"Rahman","year":"2025","journal-title":"Applied Food Research"},{"issue":"1","key":"10.1016\/j.crfs.2026.101519_bib20","doi-asserted-by":"crossref","DOI":"10.1186\/2047-217X-2-13","article-title":"The role of reporting standards for metabolite annotation and identification in metabolomic studies","volume":"2","author":"Salek","year":"2013","journal-title":"GigaScience"},{"issue":"9","key":"10.1016\/j.crfs.2026.101519_bib21","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/s41575-021-00440-6","article-title":"The international Scientific association of probiotics and prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics","volume":"18","author":"Salminen","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"9","key":"10.1016\/j.crfs.2026.101519_bib22","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/s41575-021-00440-6","article-title":"The international Scientific association of probiotics and prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics","volume":"18","author":"Salminen","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.crfs.2026.101519_bib23","article-title":"Postbiotics and their health modulatory biomolecules","volume":"12","author":"Scott","year":"2022"},{"issue":"7","key":"10.1016\/j.crfs.2026.101519_bib24","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.32604\/biocell.2025.065467","article-title":"Anti-photoaging activities of Limosilactobacillus reuteri culture broth","volume":"49","author":"Song","year":"2025","journal-title":"Biocell"},{"issue":"3","key":"10.1016\/j.crfs.2026.101519_bib25","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s11306-007-0082-2","article-title":"Proposed minimum reporting standards for chemical analysis chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)","volume":"3","author":"Sumner","year":"2007","journal-title":"Metabolomics : Official Journal of the Metabolomic Society"},{"key":"10.1016\/j.crfs.2026.101519_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122748","article-title":"Probiotics and the microbiota-gut-brain axis in neurodegeneration: beneficial effects and mechanistic insights","volume":"350","author":"Taghizadeh Ghassab","year":"2024","journal-title":"Life Sci."},{"key":"10.1016\/j.crfs.2026.101519_bib27","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.wasman.2016.03.034","article-title":"Lactic acid fermentation from food waste with indigenous microbiota: effects of pH, temperature and high OLR","volume":"52","author":"Tang","year":"2016","journal-title":"Waste Manag."},{"issue":"2","key":"10.1016\/j.crfs.2026.101519_bib28","article-title":"What's in a name? Metabolite identification: challenges and pitfalls in untargeted metabolomics","volume":"22","author":"Theodoridis","year":"2026","journal-title":"Metabolomics"},{"issue":"16","key":"10.1016\/j.crfs.2026.101519_bib29","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26167857","article-title":"Molecular mechanisms of probiotic action against gastrointestinal cancers","volume":"26","author":"Thoda","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.crfs.2026.101519_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.897387","article-title":"Antioxidant mechanism of Lactiplantibacillus plantarum KM1 under H2O2 stress by proteomics analysis","volume":"13","author":"Tian","year":"2022","journal-title":"Front. Microbiol."},{"issue":"6","key":"10.1016\/j.crfs.2026.101519_bib31","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/nmeth.3393","article-title":"MS-DIAL: Data-independent MS\/MS deconvolution for comprehensive metabolome analysis","volume":"12","author":"Tsugawa","year":"2015","journal-title":"Nat. Methods"},{"issue":"5","key":"10.1016\/j.crfs.2026.101519_bib32","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1080\/10826068.2012.656869","article-title":"Purification and characterization of a proteinase from the probiotic Lactobacillus rhamnosus OXY","volume":"42","author":"Wa\u015bko","year":"2012","journal-title":"Prep. Biochem. Biotechnol."},{"key":"10.1016\/j.crfs.2026.101519_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2023.115269","article-title":"Antioxidant properties and molecular mechanisms of Lactiplantibacillus plantarum ZJ316: a potential probiotic resource","volume":"187","author":"Wu","year":"2023","journal-title":"Lebensm. Wiss. Technol."},{"issue":"1","key":"10.1016\/j.crfs.2026.101519_bib34","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/fft2.10","article-title":"Guidelines for antioxidant assays for food components","volume":"1","author":"Xiao","year":"2020","journal-title":"Food Frontiers"}],"container-title":["Current Research in Food Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665927126002194?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665927126002194?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T19:36:49Z","timestamp":1794339409000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2665927126002194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":34,"alternative-id":["S2665927126002194"],"URL":"https:\/\/doi.org\/10.1016\/j.crfs.2026.101519","relation":{},"ISSN":["2665-9271"],"issn-type":[{"value":"2665-9271","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Linking antioxidant activity to strain-specific exometabolomic profiles in probiotic Lactobacillus paracasei and Lactobacillus plantarum fermentation supernatants","name":"articletitle","label":"Article Title"},{"value":"Current Research in Food Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crfs.2026.101519","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101519"}}