{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:52:01Z","timestamp":1780051921967,"version":"3.53.1"},"reference-count":232,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["303247\/2019\u20133"],"award-info":[{"award-number":["303247\/2019\u20133"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Critical Reviews in Oncology\/Hematology"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.critrevonc.2022.103796","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T02:23:50Z","timestamp":1661739830000},"page":"103796","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Cellular reprogramming, chemoresistance, and dietary interventions in breast cancer"],"prefix":"10.1016","volume":"179","author":[{"given":"Irislene Costa","family":"Pereira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabele Fraz\u00e3o","family":"Mascarenhas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vin\u00edcius Cooper","family":"Capetini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Michel Pinheiro","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Macedo","family":"Rogero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Leonardo","family":"Torres-Leal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s10549-011-1705-x","article-title":"Behavioral risk factors and their relationship to tumor characteristics in Hispanic and non-Hispanic white long-term breast cancer survivors","volume":"131","author":"Abdel-Maksoud","year":"2012","journal-title":"Breast Cancer Res. Treat."},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib2","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/s41430-020-00847-5","article-title":"A longitudinal association between the traditional Japanese diet score and incidence and mortality of breast cancer-an ecological study","volume":"75","author":"Abe","year":"2021","journal-title":"Eur. J. Clin. Nutr."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib3","first-page":"827","article-title":"Curcumin induces re-expression of BRCA1 and suppression of \u03b3 synuclein by modulating DNA promoter methylation in breast cancer cell lines","volume":"43","author":"Al-Yousef","year":"2020","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.critrevonc.2022.103796_bib4","doi-asserted-by":"crossref","unstructured":"Alexandre, L.S., Oliveira, M.S., Dittz, D., Sousa, R.W.R., Ferreira, P.M.P., Pessoa, C., Varotti, F.P., Sanchez, B.A.M., Banfi, F.F., Chaves, M.H., Vieira J\u00fanior, G.M., 2020. Flavonoids, cytotoxic, and antimalarial activities of Dipteryx lacunifera. Rev. Bras. Farmacogn 30, 544-550, 2020. doi:0.1007\/s43450-020-00082-w.","DOI":"10.1007\/s43450-020-00082-w"},{"issue":"24","key":"10.1016\/j.critrevonc.2022.103796_bib5","doi-asserted-by":"crossref","first-page":"12820","DOI":"10.18632\/oncotarget.2667","article-title":"TAp73 promotes anabolism","volume":"5","author":"Amelio","year":"2014","journal-title":"Oncotarget"},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib6","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.8860","article-title":"Metabolically healthy obesity redefined","volume":"4","author":"April-Sanders","year":"2021","journal-title":"JAMA Netw. Open"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib7","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s10549-009-0512-0","article-title":"The effect of body mass index on overall and disease-free survival in node-positive breast cancer patients treated with docetaxel and doxorubicin-containing adjuvant chemotherapy: The experience of the BIG 02-98 trial","volume":"119","author":"Azambuja","year":"2010","journal-title":"Breast Cancer Res. Treat."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib8","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.celrep.2019.06.010","article-title":"Amino acid transporters to support aspartate and glutamate dependency sustains endocrine resistance in breast cancer","volume":"28","author":"Bacci","year":"2019","journal-title":"Cell Rep."},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib9","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/nrc3958","article-title":"The tumour microenvironment after radiotherapy: Mechanisms of resistance and recurrence","volume":"15","author":"Barker","year":"2015","journal-title":"Nature Rev. Cancer"},{"issue":"19","key":"10.1016\/j.critrevonc.2022.103796_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201801386","article-title":"Stilbenoid-mediated epigenetic activation of semaphorin 3A in breast cancer cells involves changes in dynamic interactions of DNA with DNMT3A and NF1C Transcription Factor","volume":"63","author":"Beetch","year":"2019","journal-title":"Mol. Nutr. Food Res."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib11","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.immuni.2015.09.001","article-title":"Metabolic reprogramming of immune cells in cancer progression","volume":"43","author":"Biswas","year":"2015","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib12","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1073\/pnas.1815345116","article-title":"Toward understanding cancer stem cell heterogeneity in the tumor microenvironment","volume":"116","author":"Bocci","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"18","key":"10.1016\/j.critrevonc.2022.103796_bib13","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1158\/0008-5472.CAN-13-0530","article-title":"Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer","volume":"73","author":"Bochet","year":"2013","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib14","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2015.1061176","article-title":"Biological network-driven gene selection identifies a stromal immune module as a key determinant of triple-negative breast carcinoma prognosis","volume":"5","author":"Bonsang-Kitzis","year":"2016","journal-title":"Oncoimmunology"},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib15","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/bjc.2016.26","article-title":"Hexokinase 2 is a determinant of neuroblastoma metastasis","volume":"114","author":"Botzer","year":"2016","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.critrevonc.2022.103796_bib16","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.arr.2017.02.001","article-title":"Protective effects of short-term dietary restriction in surgical stress and chemotherapy","volume":"39","author":"Brandhorst","year":"2017","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.critrevonc.2022.103796_bib17","first-page":"241","article-title":"Fasting and caloric restriction in cancer prevention and treatment","volume":"207","author":"Brandhorst","year":"2016","journal-title":"Recent Results Cancer Res. Fortschr. Der Krebsforsch. Prog. Dans Les. Rech. Sur Le. Cancer"},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib18","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA: A Cancer J. Clin."},{"issue":"9","key":"10.1016\/j.critrevonc.2022.103796_bib19","doi-asserted-by":"crossref","first-page":"2990","DOI":"10.3390\/nu13092990","article-title":"Adherence to dietary recommendations after one year of intervention in breast cancer women: The DIANA-5 trial","volume":"13","author":"Bruno","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.critrevonc.2022.103796_bib20","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jprot.2013.10.002","article-title":"Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: Alterations in glutamine and beta-alanine metabolism","volume":"94","author":"Budczies","year":"2013","journal-title":"J. Proteom."},{"key":"10.1016\/j.critrevonc.2022.103796_bib21","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1186\/1471-2164-13-334","article-title":"Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue\u2014A GC-TOFMS based metabolomics study","volume":"13","author":"Budczies","year":"2012","journal-title":"BMC Genom."},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib22","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1002\/ijc.29152","article-title":"Glutamate enrichment as new diagnostic opportunity in breast cancer","volume":"136","author":"Budczies","year":"2015","journal-title":"Int. J. Cancer"},{"issue":"12","key":"10.1016\/j.critrevonc.2022.103796_bib23","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1016\/j.jacc.2017.07.763","article-title":"Metabolically healthy obese and incident cardiovascular disease events among 3.5 million men and women","volume":"70","author":"Caleyachetty","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib24","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/annonc\/mdx651","article-title":"Characterization of male breast cancer: Results of the EORTC 10085\/TBCRC\/BIG\/NABCG International Male Breast Cancer Program","volume":"29","author":"Cardoso","year":"2018","journal-title":"Ann. Oncol.: Off. J. Eur. Soc. Med. Oncol."},{"key":"10.1016\/j.critrevonc.2022.103796_bib25","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1472-6807-13-27","article-title":"Structural insights into Resveratrol\u2019s antagonist and partial agonist actions on estrogen receptor alpha","volume":"13","author":"Chakraborty","year":"2013","journal-title":"BMC Struct. Biol."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib26","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1210\/me.2007-0356","article-title":"Estrogen receptors alpha and beta as determinants of gene expression: Influence of ligand, dose, and chromatin binding","volume":"22","author":"Chang","year":"2008","journal-title":"Mol. Endocrinol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib27","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/jcb.27442","article-title":"Curcumin-mediated demethylation of the proximal promoter CpG island enhances the KLF4 recruitment that leads to increased expression of p21Cip1 in vitro","volume":"120","author":"Chatterjee","year":"2019","journal-title":"J. Cell. Biochem."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib28","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/s41556-019-0299-0","article-title":"Extracellular vesicle-packaged HIF-1\u03b1-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells","volume":"21","author":"Chen","year":"2019","journal-title":"Nat. Cell Biol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib29","first-page":"85","article-title":"Nrf2 expression in endometrial serous carcinomas and its precancers","volume":"4","author":"Chen","year":"2011","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3390\/metabo10070289","article-title":"Metabolic reprogramming of chemoresistant cancer cells and the potential significance of metabolic regulation in the reversal of cancer chemoresistance","volume":"10","author":"Chen","year":"2020","journal-title":"Metabolites"},{"key":"10.1016\/j.critrevonc.2022.103796_bib31","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3389\/fendo.2016.00030","article-title":"Adipose tissue remodeling: its role in energy metabolism and metabolic disorders","volume":"7","author":"Choe","year":"2016","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.critrevonc.2022.103796_bib32","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/9369358","article-title":"Expression of pentose phosphate pathway-related proteins in breast cancer","volume":"2018","author":"Choi","year":"2018","journal-title":"Dis. Markers"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib33","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.trecan.2017.01.005","article-title":"Glutamine metabolism in cancer: understanding the heterogeneity","volume":"3","author":"Cluntun","year":"2017","journal-title":"Trends Cancer"},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib34","first-page":"687","article-title":"Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer","volume":"32","author":"Corominas-Faja","year":"2017","journal-title":"Histol. Histopathol."},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib35","doi-asserted-by":"crossref","first-page":"790","DOI":"10.2174\/187152008785914798","article-title":"Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression","volume":"8","author":"Cosse","year":"2008","journal-title":"Anti-Cancer Agents Med. Chem."},{"issue":"1\u20132","key":"10.1016\/j.critrevonc.2022.103796_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11010-005-8841-8","article-title":"\u201cWhy do tumour cells glycolyse?\u201d: From glycolysis through citrate to lipogenesis","volume":"280","author":"Costello","year":"2005","journal-title":"Mol. Cell. Biochem."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib37","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.3390\/cancers7030828","article-title":"High-fat, high-calorie diet enhances mammary carcinogenesis and local inflammation in MMTV-PyMT mouse model of breast cancer","volume":"7","author":"Cowen","year":"2015","journal-title":"Cancers"},{"issue":"33","key":"10.1016\/j.critrevonc.2022.103796_bib38","doi-asserted-by":"crossref","first-page":"13820","DOI":"10.1073\/pnas.0905718106","article-title":"Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features","volume":"106","author":"Creighton","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib39","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3390\/ph13010002","article-title":"Dextran-curcumin nanoparticles as a methotrexate delivery vehicle: a step forward in breast cancer combination therapy","volume":"13","author":"Curcio","year":"2019","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.critrevonc.2022.103796_bib40","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.2147\/IJN.S131973","article-title":"Polyphenol nanoformulations for cancer therapy: Experimental evidence and clinical perspective","volume":"12","author":"Davatgaran-Taghipour","year":"2017","journal-title":"Int. J. Nanomed."},{"issue":"11","key":"10.1016\/j.critrevonc.2022.103796_bib41","doi-asserted-by":"crossref","first-page":"9139","DOI":"10.3390\/nu7115459","article-title":"Definition of the Mediterranean Diet: A Literature Review","volume":"7","author":"Davis","year":"2015","journal-title":"Nutrients"},{"issue":"13","key":"10.1016\/j.critrevonc.2022.103796_bib42","doi-asserted-by":"crossref","first-page":"4603","DOI":"10.18632\/oncotarget.2209","article-title":"Deregulation of the EGFR\/PI3K\/PTEN\/Akt\/mTORC1 pathway in breast cancer: Possibilities for therapeutic intervention","volume":"5","author":"Davis","year":"2014","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib43","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.cell.2012.06.013","article-title":"Cancer epigenetics: From mechanism to therapy","volume":"150","author":"Dawson","year":"2012","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib44","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/onc.2009.358","article-title":"Q\u2019s next: The diverse functions of glutamine in metabolism, cell biology and cancer","volume":"29","author":"DeBerardinis","year":"2010","journal-title":"Oncogene"},{"issue":"49","key":"10.1016\/j.critrevonc.2022.103796_bib45","doi-asserted-by":"crossref","first-page":"19345","DOI":"10.1073\/pnas.0709747104","article-title":"Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis","volume":"104","author":"DeBerardinis","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib46","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.ccell.2016.06.005","article-title":"Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity","volume":"30","author":"Di Biase","year":"2016","journal-title":"Cancer Cell"},{"key":"10.1016\/j.critrevonc.2022.103796_bib47","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ejca.2019.09.002","article-title":"Metabolic crosstalk in the breast cancer microenvironment","volume":"121","author":"Dias","year":"2019","journal-title":"Eur. J. Cancer"},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib48","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1158\/0008-5472.CAN-10-3323","article-title":"Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion","volume":"71","author":"Dirat","year":"2011","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib49","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cmet.2016.08.009","article-title":"One-carbon metabolism in health and disease","volume":"25","author":"Ducker","year":"2017","journal-title":"Cell Metab."},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib50","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1158\/1940-6207.CAPR-12-0034","article-title":"Dietary energy balance modulates epithelial-to-mesenchymal transition and tumor progression in murine claudin-low and basal-like mammary tumor models","volume":"5","author":"Dunlap","year":"2012","journal-title":"Cancer Prev. Res."},{"issue":"34","key":"10.1016\/j.critrevonc.2022.103796_bib51","doi-asserted-by":"crossref","first-page":"57622","DOI":"10.18632\/oncotarget.18038","article-title":"The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance","volume":"8","author":"Duong","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib52","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s12943-018-0851-8","article-title":"Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer","volume":"17","author":"Eastlack","year":"2018","journal-title":"Mol. Cancer"},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib53","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.molcel.2014.05.015","article-title":"Cancer epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance","volume":"54","author":"Easwaran","year":"2014","journal-title":"Mol. Cell"},{"issue":"9","key":"10.1016\/j.critrevonc.2022.103796_bib54","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1177\/2047487315623884","article-title":"Metabolically healthy obesity and cardiovascular events: A systematic review and meta-analysis","volume":"23","author":"Eckel","year":"2016","journal-title":"Eur. J. Prev. Cardiol."},{"issue":"24","key":"10.1016\/j.critrevonc.2022.103796_bib55","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.2217\/nnm-2017-0247","article-title":"Shell-crosslinked zein nanocapsules for oral codelivery of exemestane and resveratrol in breast cancer therapy","volume":"12","author":"Elzoghby","year":"2017","journal-title":"Nanomed."},{"issue":"11","key":"10.1016\/j.critrevonc.2022.103796_bib56","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1056\/NEJMra072067","article-title":"Epigenetics in cancer","volume":"358","author":"Esteller","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.critrevonc.2022.103796_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.117463","article-title":"A review on anti-cancer properties of Quercetin in breast cancer","volume":"248","author":"Ezzati","year":"2020","journal-title":"Life Sci."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib58","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3390\/nu13020332","article-title":"Curcumin from turmeric rhizome: A potential modulator of DNA methylation machinery in breast cancer inhibition","volume":"13","author":"Fabianowska-Majewska","year":"2021","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib59","doi-asserted-by":"crossref","first-page":"4761","DOI":"10.1016\/j.ijcard.2013.07.230","article-title":"Combined effect of obesity and cardio-metabolic abnormality on the risk of cardiovascular disease: A meta-analysis of prospective cohort studies","volume":"168","author":"Fan","year":"2013","journal-title":"Int. J. Cardiol."},{"issue":"6487","key":"10.1016\/j.critrevonc.2022.103796_bib60","doi-asserted-by":"crossref","first-page":"eaaw5473","DOI":"10.1126\/science.aaw5473","article-title":"Metabolic reprogramming and cancer progression","volume":"368","author":"Faubert","year":"2020","journal-title":"Sci. (N. Y., N. Y. )"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib61","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00394-020-02331-z","article-title":"Associations between serum concentration of flavonoids and breast cancer risk among Chinese women","volume":"60","author":"Feng","year":"2021","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.critrevonc.2022.103796_bib62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/3569349","article-title":"Aminoquinolines as translational models for drug repurposing: anticancer adjuvant properties and toxicokinetic-related features","volume":"2021","author":"Ferreira","year":"2021","journal-title":"J. Oncol."},{"issue":"40","key":"10.1016\/j.critrevonc.2022.103796_bib63","doi-asserted-by":"crossref","first-page":"4779","DOI":"10.2174\/1381612825666190116124233","article-title":"Cruciferous vegetables as antioxidative, chemopreventive and antineoplasic functional foods: Preclinical and clinical evidences of sulforaphane against prostate cancers","volume":"24","author":"Ferreira","year":"2019","journal-title":"Curr. Pharm. Des."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib64","doi-asserted-by":"crossref","first-page":"e16076","DOI":"10.1590\/s2175-97902017000216076","article-title":"Molecular biology of human epidermal receptors, signaling pathways and targeted therapy against cancers: new evidences and old challenges","volume":"53","author":"Ferreira","year":"2017","journal-title":"Brazilian Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.critrevonc.2022.103796_bib65","doi-asserted-by":"crossref","first-page":"k322","DOI":"10.1136\/bmj.k322","article-title":"Consumption of ultra-processed foods and cancer risk: Results from NutriNet-Sant\u00e9 prospective cohort","volume":"360","author":"Fiolet","year":"2018","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib66","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s13402-016-0282-8","article-title":"High glucose and insulin enhance uPA expression, ROS formation and invasiveness in breast cancer-derived cells","volume":"39","author":"Flores-L\u00f3pez","year":"2016","journal-title":"Cell. Oncol."},{"issue":"5976","key":"10.1016\/j.critrevonc.2022.103796_bib67","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1126\/science.1172539","article-title":"Extending healthy life span\u2014From yeast to humans","volume":"328","author":"Fontana","year":"2010","journal-title":"Sci."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib68","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.soc.2017.08.005","article-title":"Molecular subtypes and local-regional control of breast cancer","volume":"27","author":"Fragomeni","year":"2018","journal-title":"Surg. Oncol. Clin. North Am."},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib69","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/nrd.2017.22","article-title":"Pharmacological modulation of autophagy: Therapeutic potential and persisting obstacles","volume":"16","author":"Galluzzi","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.critrevonc.2022.103796_bib70","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2011.00001","article-title":"Past, present, and future of molecular and cellular oncology","author":"Galluzzi","year":"2011","journal-title":"Front. Oncol."},{"issue":"12","key":"10.1016\/j.critrevonc.2022.103796_bib71","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.1158\/0008-5472.CAN-18-0359","article-title":"The Transcriptional regulator Sin3A contributes to the oncogenic potential of STAT3","volume":"79","author":"Gambi","year":"2019","journal-title":"Cancer Res."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib72","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1158\/1535-7163.MCT-06-0024","article-title":"Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics","volume":"5","author":"Gerweck","year":"2006","journal-title":"Mol. Cancer Ther."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib73","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/jnci\/dju502","article-title":"Adaptive mitochondrial reprogramming and resistance to PI3K therapy","volume":"107","author":"Ghosh","year":"2015","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.critrevonc.2022.103796_bib74","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1146\/annurev-med-121211-091527","article-title":"Cytokines, obesity, and cancer: New insights on mechanisms linking obesity to cancer risk and progression","volume":"64","author":"Gilbert","year":"2013","journal-title":"Annu. Rev. Med."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib75","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13058-019-1141-0","article-title":"Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer","volume":"21","author":"Grinde","year":"2019","journal-title":"Breast Cancer Res.: BCR"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib76","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1038\/s41467-020-16138-3","article-title":"Fasting mimicking diet as an adjunct to\u2009neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial","volume":"11","author":"Groot","year":"2020","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib77","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1080\/10408398.2011.596955","article-title":"Mediterranean diet and cardiovascular risk factors: A systematic review","volume":"54","author":"Grosso","year":"2014","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib78","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1136\/gut.2009.188946","article-title":"Visceral fat area is an independent predictive biomarker of outcome after first-line bevacizumab-based treatment in metastatic colorectal cancer","volume":"59","author":"Guiu","year":"2010","journal-title":"Gut"},{"issue":"1\u20132","key":"10.1016\/j.critrevonc.2022.103796_bib79","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s11010-013-1723-6","article-title":"Synergistic effects of curcumin with emodin against the proliferation and invasion of breast cancer cells through upregulation of miR-34a","volume":"382","author":"Guo","year":"2013","journal-title":"Mol. Cell. Biochem."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib80","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","article-title":"Hallmarks of cancer: The next generation","volume":"144","author":"Hanahan","year":"2011","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib81","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2165\/11318100-000000000-00000","article-title":"Effect of obesity on the pharmacokinetics of drugs in humans","volume":"49","author":"Hanley","year":"2010","journal-title":"Clin. Pharmacokinet."},{"issue":"41","key":"10.1016\/j.critrevonc.2022.103796_bib82","doi-asserted-by":"crossref","first-page":"67183","DOI":"10.18632\/oncotarget.11594","article-title":"TP53 mutation hits energy metabolism and increases glycolysis in breast cancer","volume":"7","author":"Harami-Papp","year":"2016","journal-title":"Oncotarget"},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib83","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.clon.2010.02.001","article-title":"Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer","volume":"22","author":"Healy","year":"2010","journal-title":"Clin. Oncol."},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib84","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1080\/01635581.2017.1359316","article-title":"Investigating the antiangiogenic, anti-drug resistance and apoptotic effects of soy isoflavone extract alone or in combination with docetaxel on murine 4T1 breast tumor model","volume":"69","author":"Hejazi","year":"2017","journal-title":"Nutr. Cancer"},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib85","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000217529","article-title":"Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue","volume":"8","author":"Hennipman","year":"1987","journal-title":"Tumour Biol.: J. Int. Soc. Oncodev. Biol. Med."},{"issue":"10","key":"10.1016\/j.critrevonc.2022.103796_bib86","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/nrc3599","article-title":"Cancer drug resistance: An evolving paradigm","volume":"13","author":"Holohan","year":"2013","journal-title":"Nat. Rev. Cancer"},{"issue":"7719","key":"10.1016\/j.critrevonc.2022.103796_bib87","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/s41586-018-0343-4","article-title":"Suppression of insulin feedback enhances the efficacy of PI3K inhibitors","volume":"560","author":"Hopkins","year":"2018","journal-title":"Nat."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib88","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0056256","article-title":"Methylation of BRCA1 promoter region Is associated with unfavorable prognosis in women with early-stage breast cancer","volume":"8","author":"Hsu","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.critrevonc.2022.103796_bib89","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/978-3-642-38007-5_2","article-title":"Obesity, energy balance, and cancer: A mechanistic perspective","volume":"159","author":"Hursting","year":"2014","journal-title":"Cancer Treat. Res."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib90","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/2049-3002-1-10","article-title":"Calorie restriction and cancer prevention: A mechanistic perspective","volume":"1","author":"Hursting","year":"2013","journal-title":"Cancer Metab."},{"issue":"39","key":"10.1016\/j.critrevonc.2022.103796_bib91","doi-asserted-by":"crossref","first-page":"25545","DOI":"10.18632\/oncotarget.25370","article-title":"Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin","volume":"9","author":"Inao","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.critrevonc.2022.103796_bib92","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.biocel.2019.05.020","article-title":"Resveratrol up-regulates ATP2A3 gene expression in breast cancer cell lines through epigenetic mechanisms","volume":"113","author":"Izquierdo-Torres","year":"2019","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib93","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.1016\/S0021-9258(17)41939-9","article-title":"Coordination of membrane phospholipid synthesis with the cell cycle","volume":"269","author":"Jackowski","year":"1994","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib94","first-page":"606","article-title":"A ketogenic diet attenuates proliferation and stemness of glioma stem\u2011like cells by altering metabolism resulting in increased ROS production","volume":"56","author":"Ji","year":"2020","journal-title":"Int. J. Oncol."},{"issue":"35","key":"10.1016\/j.critrevonc.2022.103796_bib95","doi-asserted-by":"crossref","first-page":"4203","DOI":"10.1200\/JCO.2016.68.4480","article-title":"Obesity and breast cancer prognosis: evidence, challenges, and opportunities","volume":"34","author":"Jiralerspong","year":"2016","journal-title":"J. Clin. Oncol.: Off. J. Am. Soc. Clin. Oncol."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib96","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.freeradbiomed.2006.12.005","article-title":"Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma","volume":"42","author":"Johnson","year":"2007","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib97","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.cell.2007.01.029","article-title":"The epigenomics of cancer","volume":"128","author":"Jones","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.critrevonc.2022.103796_bib98","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.exger.2015.02.011","article-title":"Overexpression of the adiponectin gene mimics the metabolic and stress resistance effects of calorie restriction, but not the anti-tumor effect","volume":"64","author":"Kamohara","year":"2015","journal-title":"Exp. Gerontol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib99","doi-asserted-by":"crossref","first-page":"117","DOI":"10.3346\/jkms.2007.22.1.117","article-title":"Relationship of serum adiponectin and resistin levels with breast cancer risk","volume":"22","author":"Kang","year":"2007","journal-title":"J. Korean Med. Sci."},{"key":"10.1016\/j.critrevonc.2022.103796_bib100","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.phymed.2018.11.017","article-title":"Development of curcumin-loaded gemini surfactant nanoparticles: Synthesis, characterization and evaluation of anticancer activity against human breast cancer cell lines","volume":"57","author":"Karimpour","year":"2019","journal-title":"Phytomedicine"},{"key":"10.1016\/j.critrevonc.2022.103796_bib101","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.drup.2014.12.002","article-title":"Host effects contributing to cancer therapy resistance","volume":"19","author":"Katz","year":"2015","journal-title":"Drug Resist. Update.: Rev. Comment. Antimicrob. Anticancer Chemother."},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib102","doi-asserted-by":"crossref","first-page":"637","DOI":"10.4103\/0253-7613.194852","article-title":"Genistein synergizes centchroman action in human breast cancer cells","volume":"48","author":"Kaushik","year":"2016","journal-title":"Indian J. Pharmacol."},{"issue":"8","key":"10.1016\/j.critrevonc.2022.103796_bib103","doi-asserted-by":"crossref","DOI":"10.3390\/cells8080840","article-title":"Role of miRNA-regulated cancer stem cells in the pathogenesis of human malignancies","volume":"8","author":"Khan","year":"2019","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib104","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.cytogfr.2013.10.001","article-title":"Role of adipokines and cytokines in obesity-associated breast cancer: Therapeutic targets","volume":"24","author":"Khan","year":"2013","journal-title":"Cytokine Growth Factor Rev."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib105","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12937-020-00596-y","article-title":"Does a ketogenic diet have beneficial effects on quality of life, physical activity or biomarkers in patients with breast cancer: A randomized controlled clinical trial","volume":"19","author":"Khodabakhshi","year":"2020","journal-title":"Nutr. J."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib106","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13058-018-0944-8","article-title":"The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells","volume":"20","author":"Kim","year":"2018","journal-title":"Breast Cancer Res."},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib107","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0101004","article-title":"Differential expression of enzymes associated with serine\/glycine metabolism in different breast cancer subtypes","volume":"9","author":"Kim","year":"2014","journal-title":"PLOS ONE"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib108","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1530\/ERC-12-0398","article-title":"Expression of glutamine metabolism-related proteins according to molecular subtype of breast cancer","volume":"20","author":"Kim","year":"2013","journal-title":"Endocr. -Relat. Cancer"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib109","article-title":"Differential expression of lipid metabolism-related proteins in different breast cancer subtypes","volume":"10","author":"Kim","year":"2015","journal-title":"PLOS ONE"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib110","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s10549-020-06049-8","article-title":"Association of mammographic density measures and breast cancer \u201cintrinsic\u201d molecular subtypes","volume":"187","author":"Kleinstern","year":"2021","journal-title":"Breast Cancer Res. Treat."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib111","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1159\/000484045","article-title":"Fasting, fats, and physics: combining ketogenic and radiation therapy against cancer","volume":"25","author":"Klement","year":"2018","journal-title":"Complement. Med. Res."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib112","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41416-019-0650-z","article-title":"Reprogramming of fatty acid metabolism in cancer","volume":"122","author":"Koundouros","year":"2020","journal-title":"Br. J. Cancer"},{"issue":"11","key":"10.1016\/j.critrevonc.2022.103796_bib113","doi-asserted-by":"crossref","first-page":"758","DOI":"10.7326\/0003-4819-159-11-201312030-00008","article-title":"Are metabolically healthy overweight and obesity benign conditions?: A systematic review and meta-analysis","volume":"159","author":"Kramer","year":"2013","journal-title":"Ann. Intern. Med."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib114","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.molonc.2014.01.005","article-title":"MiR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2","volume":"8","author":"Kronski","year":"2014","journal-title":"Mol. Oncol."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib115","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1158\/1535-7163.MCT-10-0802","article-title":"Lipoprotein lipase links dietary fat to solid tumor cell proliferation","volume":"10","author":"Kuemmerle","year":"2011","journal-title":"Mol. Cancer Ther."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib116","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/S0899-9007(99)00266-X","article-title":"Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology","volume":"16","author":"Kuhajda","year":"2000","journal-title":"Nutr."},{"issue":"9","key":"10.1016\/j.critrevonc.2022.103796_bib117","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0185092","article-title":"Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition","volume":"12","author":"Lampa","year":"2017","journal-title":"PloS One"},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib118","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/clpt.2014.136","article-title":"Obesity and resistance to cancer chemotherapy: Interacting roles of inflammation and metabolic dysregulation","volume":"96","author":"Lashinger","year":"2014","journal-title":"Clin. Pharmacol. Ther."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib119","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/eurheartj\/ehx448","article-title":"Separate and combined associations of obesity and metabolic health with coronary heart disease: A pan-European case-cohort analysis","volume":"39","author":"Lassale","year":"2018","journal-title":"Eur. Heart J."},{"issue":"124","key":"10.1016\/j.critrevonc.2022.103796_bib120","doi-asserted-by":"crossref","first-page":"124ra27","DOI":"10.1126\/scitranslmed.3003293","article-title":"Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy","volume":"4","author":"Lee","year":"2012","journal-title":"Sci. Transl. Med."},{"issue":"11","key":"10.1016\/j.critrevonc.2022.103796_bib121","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1038\/bjc.2011.159","article-title":"An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer","volume":"104","author":"Lee","year":"2011","journal-title":"Br. J. Cancer"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib122","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13058-018-1088-6","article-title":"Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: Role of the major vault protein (MVP)","volume":"21","author":"Lehu\u00e9d\u00e9","year":"2019","journal-title":"Breast Cancer Res.: BCR"},{"key":"10.1016\/j.critrevonc.2022.103796_bib123","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.116617","article-title":"Taxifolin inhibits breast cancer cells proliferation, migration and invasion by promoting mesenchymal to epithelial transition via \u03b2-catenin signaling","volume":"232","author":"Li","year":"2019","journal-title":"Life Sci."},{"issue":"10","key":"10.1016\/j.critrevonc.2022.103796_bib124","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1002\/ptr.5167","article-title":"Curcumin modulates miR-19\/PTEN\/AKT\/p53 axis to suppress bisphenol A-induced MCF-7 breast cancer cell proliferation","volume":"28","author":"Li","year":"2014","journal-title":"Phytother."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib125","article-title":"Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein","volume":"8","author":"Li","year":"2013","journal-title":"PloS One"},{"issue":"1 Suppl","key":"10.1016\/j.critrevonc.2022.103796_bib126","first-page":"2","article-title":"The National Cholesterol Education Program Adult Treatment Panel III guidelines","volume":"9","author":"Lipsy","year":"2003","journal-title":"J. Manag. Care Pharm.: JMCP"},{"issue":"25","key":"10.1016\/j.critrevonc.2022.103796_bib127","doi-asserted-by":"crossref","first-page":"4072","DOI":"10.1200\/JCO.2007.14.4527","article-title":"Relationship between obesity and pathologic response to neoadjuvant chemotherapy among women with operable breast cancer","volume":"26","author":"Litton","year":"2008","journal-title":"J. Clin. Oncol."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib128","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/hep.29202","article-title":"Glyceraldehyde-3-phosphate dehydrogenase promotes liver tumorigenesis by modulating phosphoglycerate dehydrogenase","volume":"66","author":"Liu","year":"2017","journal-title":"Hepatol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib129","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40364-020-00251-y","article-title":"Metabolic reprogramming in macrophage responses","volume":"9","author":"Liu","year":"2021","journal-title":"Biomark. Res."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib130","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/path.1706","article-title":"Molecular mechanisms of drug resistance","volume":"205","author":"Longley","year":"2005","journal-title":"J. Pathol."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib131","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.tips.2009.11.004","article-title":"Calorie restriction and cancer prevention: Metabolic and molecular mechanisms","volume":"31","author":"Longo","year":"2010","journal-title":"Trends Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib132","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.cmet.2013.12.008","article-title":"Fasting: Molecular mechanisms and clinical applications","volume":"19","author":"Longo","year":"2014","journal-title":"Cell Metab."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib133","doi-asserted-by":"crossref","first-page":"794","DOI":"10.3390\/cancers13040794","article-title":"Proteomic analysis of low-grade, early-stage endometrial carcinoma reveals new dysregulated pathways associated with cell death and cell signaling","volume":"13","author":"L\u00f3pez-Janeiro","year":"2021","journal-title":"Cancers"},{"issue":"11","key":"10.1016\/j.critrevonc.2022.103796_bib134","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002179","article-title":"Genetic predisposition to an impaired metabolism of the branched-chain amino acids and risk of type 2 diabetes: A Mendelian randomisation analysis","volume":"13","author":"Lotta","year":"2016","journal-title":"PLoS Med."},{"issue":"8","key":"10.1016\/j.critrevonc.2022.103796_bib135","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/nrclinonc.2013.108","article-title":"Chemotherapy dosing in overweight and obese patients with cancer","volume":"10","author":"Lyman","year":"2013","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"14","key":"10.1016\/j.critrevonc.2022.103796_bib136","article-title":"Aldehyde dehydrogenase 1 (ALDH1) expression is an independent prognostic factor in triple negative breast cancer (TNBC)","volume":"96","author":"Ma","year":"2017","journal-title":"Med."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib137","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1083\/jcb.200906011","article-title":"Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1\/Polzeta-dependent mechanism","volume":"186","author":"Madia","year":"2009","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.critrevonc.2022.103796_bib138","doi-asserted-by":"crossref","first-page":"23","DOI":"10.4137\/CPath.S31563","article-title":"Diversity of breast carcinoma: histological subtypes and clinical relevance","volume":"8","author":"Makki","year":"2015","journal-title":"Clin. Med. Insights Pathol."},{"issue":"9","key":"10.1016\/j.critrevonc.2022.103796_bib139","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.3390\/biom11091336","article-title":"Mediterranean diet food components as possible adjuvant therapies to counteract breast and prostate cancer progression to bone metastasis","volume":"11","author":"Maroni","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.critrevonc.2022.103796_bib140","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1743-7075-5-33","article-title":"Drug\/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet","volume":"5","author":"Marsh","year":"2008","journal-title":"Nutr. Metab."},{"issue":"18","key":"10.1016\/j.critrevonc.2022.103796_bib141","doi-asserted-by":"crossref","first-page":"6456","DOI":"10.1002\/cam4.4158","article-title":"Relationship of established risk factors with breast cancer subtypes","volume":"10","author":"McCarthy","year":"2021","journal-title":"Cancer Med."},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib142","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/jphp.12539","article-title":"Increasing role of the cancer chemotherapeutic doxorubicin in cellular metabolism","volume":"68","author":"Meredith","year":"2016","journal-title":"J. Pharm. Pharmacol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib143","doi-asserted-by":"crossref","first-page":"23","DOI":"10.4048\/jbc.2013.16.1.23","article-title":"Expression of DNA methyltransferases in breast cancer patients and to analyze the effect of natural compounds on DNA methyltransferases and associated proteins","volume":"16","author":"Mirza","year":"2013","journal-title":"J. Breast Cancer"},{"issue":"17","key":"10.1016\/j.critrevonc.2022.103796_bib144","doi-asserted-by":"crossref","first-page":"29487","DOI":"10.18632\/oncotarget.15494","article-title":"Fatty acid metabolism in breast cancer subtypes","volume":"8","author":"Monaco","year":"2017","journal-title":"Oncotarget"},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib145","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/advances\/nmz046","article-title":"Epigenetic gene regulation by dietary ompounds in cancer prevention","volume":"10","author":"Montgomery","year":"2019","journal-title":"Adv. Nutr."},{"issue":"16","key":"10.1016\/j.critrevonc.2022.103796_bib146","doi-asserted-by":"crossref","first-page":"5622","DOI":"10.1158\/1078-0432.CCR-04-0308","article-title":"Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors","volume":"10","author":"Mukherjee","year":"2004","journal-title":"Clin. Cancer Res.: Off. J. Am. Assoc. Cancer Res."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib147","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/19430892.2012.691799","article-title":"Curcumin inhibits histone deacetylase leading to cell cycle arrest and apoptosis via upregulation of p21 in breast cancer cell lines","volume":"4","author":"Mukherjee","year":"2012","journal-title":"Int. J. Green. Nanotechnol."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib148","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018085","article-title":"Influence of caloric restriction on constitutive expression of NF-\u03baB in an experimental mouse astrocytoma","volume":"6","author":"Mulrooney","year":"2011","journal-title":"PLOS ONE"},{"issue":"9","key":"10.1016\/j.critrevonc.2022.103796_bib149","doi-asserted-by":"crossref","DOI":"10.3390\/cells8090957","article-title":"Mechanisms of chemotherapy resistance in triple-begative breast cancer - How we can rise to the challenge","volume":"8","author":"Nedeljkovi\u0107","year":"2019","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib150","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1158\/1535-7163.MCT-06-0529","article-title":"MRP8\/ABCC11 directly confers resistance to 5-fluorouracil","volume":"6","author":"Oguri","year":"2007","journal-title":"Mol. Cancer Ther."},{"issue":"35","key":"10.1016\/j.critrevonc.2022.103796_bib151","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.1200\/JCO.2016.69.4638","article-title":"Addressing the role of obesity in endometrial cancer risk, prevention, and treatment","volume":"34","author":"Onstad","year":"2016","journal-title":"J. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib152","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1513750","article-title":"Adaptive randomization of Neratinib in early breast cancer","volume":"375","author":"Park","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.critrevonc.2022.103796_bib153","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.semcancer.2018.01.007","article-title":"Epigenetics of breast cancer: Biology and clinical implication in the era of precision medicine","volume":"51","author":"Pasculli","year":"2018","journal-title":"Semin. Cancer Biol."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib154","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.ccr.2013.06.014","article-title":"Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer","volume":"24","author":"Patra","year":"2013","journal-title":"Cancer Cell"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib155","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cmet.2015.12.006","article-title":"The emerging hallmarks of cancer metabolism","volume":"23","author":"Pavlova","year":"2016","journal-title":"Cell Metab."},{"issue":"1\u20133","key":"10.1016\/j.critrevonc.2022.103796_bib156","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0005-2728(02)00248-7","article-title":"Mitochondrial bound type II hexokinase: A key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention","volume":"1555","author":"Pedersen","year":"2002","journal-title":"Biochim. Et. Biophys. Acta"},{"issue":"Suppl 6","key":"10.1016\/j.critrevonc.2022.103796_bib157","article-title":"Pathological and molecular diagnosis of triple-negative breast cancer: A clinical perspective","volume":"23","author":"Penault-Llorca","year":"2012","journal-title":"Ann. Oncol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib158","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.celrep.2018.03.077","article-title":"Molecular characterization and clinical relevance of metabolic expression subtypes in human cancers","volume":"23","author":"Peng","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.critrevonc.2022.103796_bib159","doi-asserted-by":"crossref","first-page":"2051279","DOI":"10.1155\/2018\/2051279","article-title":"In vitro and ex vivo chemopreventive action of Mauritia flexuosa products.","volume":"2018","author":"Pereira-Freire","year":"2018","journal-title":"Evid.-Based Complement. Alternat. Med."},{"issue":"6797","key":"10.1016\/j.critrevonc.2022.103796_bib160","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/35021093","article-title":"Molecular portraits of human breast tumours","volume":"406","author":"Perou","year":"2000","journal-title":"Nature"},{"issue":"6290","key":"10.1016\/j.critrevonc.2022.103796_bib161","doi-asserted-by":"crossref","first-page":"aad9780","DOI":"10.1126\/science.aad9780","article-title":"Epigenetic balance of gene expression by Polycomb and COMPASS families","volume":"352","author":"Piunti","year":"2016","journal-title":"Sci."},{"issue":"7360","key":"10.1016\/j.critrevonc.2022.103796_bib162","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/nature10350","article-title":"Functional genomics reveal that the serine synthesis pathway is essential in breast cancer","volume":"476","author":"Possemato","year":"2011","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib163","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1158\/1078-0432.CCR-19-2023","article-title":"Randomized Phase 0\/I trial of the mitochondrial inhibitor ME-344 or placebo added to bevacizumab in early HER2-negative breast cancer","volume":"26","author":"Quintela-Fandino","year":"2020","journal-title":"Clin. Cancer Res."},{"issue":"24","key":"10.1016\/j.critrevonc.2022.103796_bib164","doi-asserted-by":"crossref","first-page":"8215","DOI":"10.1073\/pnas.0708100105","article-title":"Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy","volume":"105","author":"Raffaghello","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib165","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/S0006-2952(03)00468-4","article-title":"Tumor acidity, ion trapping and chemotherapeutics. II. pH-dependent partition coefficients predict importance of ion trapping on pharmacokinetics of weakly basic chemotherapeutic agents","volume":"66","author":"Raghunand","year":"2003","journal-title":"Biochem. Pharmacol."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib166","doi-asserted-by":"crossref","first-page":"571","DOI":"10.3390\/metabo5040571","article-title":"Cancer metabolism and drug resistance","volume":"5","author":"Rahman","year":"2015","journal-title":"Metabolites"},{"issue":"9","key":"10.1016\/j.critrevonc.2022.103796_bib167","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1080\/10408398.2016.1263597","article-title":"Resveratrol as an anti-cancer agent: A review","volume":"58","author":"Rauf","year":"2018","journal-title":"Crit. Rev. Food Sci. Nutr."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib168","doi-asserted-by":"crossref","first-page":"853","DOI":"10.4103\/0973-1482.139267","article-title":"An overview of doxorubicin formulations in cancer therapy","volume":"10","author":"Rivankar","year":"2014","journal-title":"J. Cancer Res. Ther."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib169","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/nm.2305","article-title":"Cancer epigenetics reaches mainstream oncology","volume":"17","author":"Rodr\u00edguez-Paredes","year":"2011","journal-title":"Nat. Med."},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib170","doi-asserted-by":"crossref","DOI":"10.3945\/cdn.117.000562","article-title":"Genistein Prevents BRCA1 CpG methylation and proliferation in human breast cancer cells with activated aromatic hydrocarbon receptor","volume":"1","author":"Romagnolo","year":"2017","journal-title":"Curr. Dev. Nutr."},{"key":"10.1016\/j.critrevonc.2022.103796_bib171","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.foodchem.2015.09.085","article-title":"Understanding genistein in cancer: The \u201cgood\u201d and the \u201cbad\u201d effects: A review","volume":"196","author":"Russo","year":"2016","journal-title":"Food Chem."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib172","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1016\/j.clnu.2020.10.037","article-title":"A review of fasting effects on the response of cancer to chemotherapy","volume":"40","author":"Sadeghian","year":"2021","journal-title":"Clin. Nutr."},{"issue":"12","key":"10.1016\/j.critrevonc.2022.103796_bib173","doi-asserted-by":"crossref","first-page":"988","DOI":"10.18632\/aging.100114","article-title":"Fasting and cancer treatment in humans: A case series report","volume":"1","author":"Safdie","year":"2009","journal-title":"Aging"},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib174","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/nrc.2017.5","article-title":"Tissue-specific tumorigenesis: Context matters","volume":"17","author":"Schneider","year":"2017","journal-title":"Nat. Rev. Cancer"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib175","doi-asserted-by":"crossref","DOI":"10.3390\/nu12030761","article-title":"Flavonoids and other polyphenols act as epigenetic modifiers in breast cancer","volume":"12","author":"Selvakumar","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.critrevonc.2022.103796_bib176","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3389\/fnut.2020.00021","article-title":"Consideration of ketogenic metabolic therapy as a complementary or alternative approach for managing breast cancer","volume":"7","author":"Seyfried","year":"2020","journal-title":"Front. Nutr."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib177","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2217\/14622416.9.1.105","article-title":"ABC multidrug transporters: Structure, function and role in chemoresistance","volume":"9","author":"Sharom","year":"2008","journal-title":"Pharmacogenomics"},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib178","doi-asserted-by":"crossref","first-page":"732","DOI":"10.3390\/cancers11050732","article-title":"Targeting cancer stem cells: A strategy for effective eradication of cancer","volume":"11","author":"Shibata","year":"2019","journal-title":"Cancers"},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib179","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1158\/0008-5472.CAN-14-2249","article-title":"Starvation promotes REV1 SUMOylation and p53-dependent sensitization of melanoma and breast cancer cells","volume":"75","author":"Shim","year":"2015","journal-title":"Cancer Res."},{"key":"10.1016\/j.critrevonc.2022.103796_bib180","doi-asserted-by":"crossref","first-page":"728759","DOI":"10.3389\/fcell.2021.728759","article-title":"Glucose metabolism and glucose transporters in breast cancer","volume":"9","author":"Shin","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib181","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1440-6047.2001.00235.x","article-title":"History and characteristics of Okinawan longevity food","volume":"10","author":"Sho","year":"2001","journal-title":"Asia Pac. J. Clin. Nutr."},{"key":"10.1016\/j.critrevonc.2022.103796_bib182","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/978-3-030-20301-6_16","article-title":"Epigenetics of breast cancer: Clinical status of epi-drugs and phytochemicals","volume":"1152","author":"Shukla","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"issue":"13","key":"10.1016\/j.critrevonc.2022.103796_bib183","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1080\/15384101.2018.1471314","article-title":"Caloric restriction counteracts chemotherapy-induced inflammation and increases response to therapy in a triple negative breast cancer model","volume":"17","author":"Simone","year":"2018","journal-title":"Cell Cycle (Georget., Tex. )"},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib184","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/s12033-009-9220-6","article-title":"Pharmacogenetics of membrane transporters: An update on current approaches","volume":"44","author":"Sissung","year":"2010","journal-title":"Mol. Biotechnol."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib185","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.celrep.2016.09.045","article-title":"Addiction to coupling of the warburg effect with glutamine catabolism in cancer cells","volume":"17","author":"Smith","year":"2016","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib186","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1080\/01635581.2020.1756354","article-title":"Association between adherence to \u201cDietary Approaches to Stop Hypertension\u201d eating plan and breast cancer","volume":"73","author":"Soltani","year":"2021","journal-title":"Nutr. Cancer"},{"issue":"18","key":"10.1016\/j.critrevonc.2022.103796_bib187","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1016\/j.ejca.2004.08.021","article-title":"Molecular portraits of breast cancer: tumour subtypes as distinct disease entities","volume":"40","author":"S\u00f8rlie","year":"2004","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.critrevonc.2022.103796_bib188","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.3389\/fonc.2019.01003","article-title":"Novel and alternative targets against breast cancer stemness to combat chemoresistance","volume":"9","author":"Sridharan","year":"2019","journal-title":"Front. Oncol."},{"issue":"9","key":"10.1016\/j.critrevonc.2022.103796_bib189","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1038\/ijo.2010.69","article-title":"Body mass index at the time of diagnosis and the risk of advanced stages and poorly differentiated cancers of the breast: Findings from a case-series study","volume":"34","author":"Stark","year":"2010","journal-title":"Int. J. Obes. (2005)"},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib190","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S2213-8587(13)70062-7","article-title":"Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications","volume":"1","author":"Stefan","year":"2013","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib191","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1007\/s10549-010-0792-4","article-title":"Adipocytokine resistin and breast cancer risk","volume":"123","author":"Sun","year":"2010","journal-title":"Breast Cancer Res. Treat."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib192","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3177\/jnsv.64.129","article-title":"Characteristics of the Japanese diet described in epidemiologic publications: A qualitative systematic review","volume":"64","author":"Suzuki","year":"2018","journal-title":"J. Nutr. Sci. Vitaminol."},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib193","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/bjc.1979.120","article-title":"Lipogenetic and glycolytic enzyme activities in carcinoma and nonmalignant diseases of the human breast","volume":"39","author":"Szutowicz","year":"1979","journal-title":"Br. J. Cancer"},{"issue":"14","key":"10.1016\/j.critrevonc.2022.103796_bib194","doi-asserted-by":"crossref","first-page":"11677","DOI":"10.18632\/oncotarget.24433","article-title":"Metabolic profiles of triple-negative and luminal A breast cancer subtypes in African-American identify key metabolic differences","volume":"9","author":"Tayyari","year":"2018","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib195","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1172\/JCI71180","article-title":"MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis","volume":"124","author":"Terunuma","year":"2014","journal-title":"J. Clin. Investig."},{"issue":"12","key":"10.1016\/j.critrevonc.2022.103796_bib196","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1210\/en.2016-1309","article-title":"Administration of melatonin and metformin prevents deleterious effects of circadian disruption and obesity in male rats","volume":"157","author":"Thomas","year":"2016","journal-title":"Endocrinol."},{"issue":"11","key":"10.1016\/j.critrevonc.2022.103796_bib197","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1002\/cncr.28003","article-title":"Predictors of depression in breast cancer patients treated with radiation: Role of prior chemotherapy and nuclear factor kappa B","volume":"119","author":"Torres","year":"2013","journal-title":"Cancer"},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib198","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/hep.30952","article-title":"\u03b4 cells promote steatohepatitis by orchestrating innate and adaptive immune programming","volume":"71","author":"Torres-Hernandez","year":"2020","journal-title":"Hepatol."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib199","doi-asserted-by":"crossref","first-page":"326","DOI":"10.3390\/nu10030326","article-title":"Mediterranean diet and breast cancer risk","volume":"10","author":"Turati","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.critrevonc.2022.103796_bib200","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/264039","article-title":"Dietary restriction promotes vessel maturation in a mouse astrocytoma","volume":"2012","author":"Urits","year":"2012","journal-title":"J. Oncol."},{"issue":"24","key":"10.1016\/j.critrevonc.2022.103796_bib201","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1038\/onc.2015.381","article-title":"ASCT2\/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer","volume":"35","author":"van Geldermalsen","year":"2016","journal-title":"Oncogene"},{"issue":"Suppl 3","key":"10.1016\/j.critrevonc.2022.103796_bib202","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1634\/theoncologist.13-S3-21","article-title":"Hypoxia and aggressive tumor phenotype: Implications for therapy and prognosis","volume":"13","author":"Vaupel","year":"2008","journal-title":"Oncologist"},{"issue":"7","key":"10.1016\/j.critrevonc.2022.103796_bib203","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1080\/09553002.2019.1589653","article-title":"The Warburg effect: Essential part of metabolic reprogramming and central contributor to cancer progression","volume":"95","author":"Vaupel","year":"2019","journal-title":"Int. J. Radiat. Biol."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib204","first-page":"312","article-title":"Deconstructing breast cancer cell biology and the mechanisms of multidrug resistance","volume":"1846","author":"Videira","year":"2014","journal-title":"Biochim. Et. Biophys. Acta"},{"issue":"8","key":"10.1016\/j.critrevonc.2022.103796_bib205","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1038\/bjc.1997.201","article-title":"Influence of low pH on cytotoxicity of paclitaxel, mitoxantrone and topotecan","volume":"75","author":"Vukovic","year":"1997","journal-title":"Br. J. Cancer"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib206","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2217\/nnm-2018-0266","article-title":"Size-dependent cellular uptake and TLR4 attenuation by gold nanoparticles in lung adenocarcinoma cells","volume":"14","author":"Vyas","year":"2019","journal-title":"Nanomed. (Lond., Engl. )"},{"issue":"10","key":"10.1016\/j.critrevonc.2022.103796_bib207","doi-asserted-by":"crossref","first-page":"16875","DOI":"10.18632\/oncotarget.15171","article-title":"Glucose transporter GLUT1 expression and clinical outcome in solid tumors: A systematic review and meta-analysis","volume":"8","author":"Wang","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.critrevonc.2022.103796_bib208","doi-asserted-by":"crossref","first-page":"602416","DOI":"10.3389\/fonc.2020.602416","article-title":"The metabolic mechanisms of breast cancer metastasis","volume":"10","author":"Wang","year":"2021","journal-title":"Front. Oncol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib209","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.molcel.2008.09.011","article-title":"Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis","volume":"32","author":"Wang","year":"2008","journal-title":"Mol. Cell"},{"issue":"50","key":"10.1016\/j.critrevonc.2022.103796_bib210","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1007\/BF01504608","article-title":"\u00dcber den stoffwechsel der carcinomzelle","volume":"12","author":"Warburg","year":"1924","journal-title":"Naturwissenschaften"},{"issue":"3191","key":"10.1016\/j.critrevonc.2022.103796_bib211","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1126\/science.123.3191.309","article-title":"On the origin of cancer cells","volume":"123","author":"Warburg","year":"1956","journal-title":"Sci."},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib212","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.ccr.2012.02.014","article-title":"Metabolic reprogramming: A cancer hallmark even warburg did not anticipate","volume":"21","author":"Ward","year":"2012","journal-title":"Cancer Cell"},{"key":"10.1016\/j.critrevonc.2022.103796_bib213","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2020.00745","article-title":"Craniofacial osteosarcoma\u2014pilot study on the expression of osteobiologic characteristics and hypothesis on metastasis","volume":"10","author":"Weber","year":"2020","journal-title":"Front. Oncol."},{"issue":"7336","key":"10.1016\/j.critrevonc.2022.103796_bib214","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nature09779","article-title":"Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7","volume":"471","author":"Wertz","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.critrevonc.2022.103796_bib215","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.732255","article-title":"The effects of diet and exercise on endogenous estrogens and subsequent breast cancer risk in postmenopausal women","volume":"12","author":"Wiggs","year":"2021","journal-title":"Front. Endocrinol."},{"issue":"6","key":"10.1016\/j.critrevonc.2022.103796_bib216","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1021\/mp200292c","article-title":"Drug resistance and cellular adaptation to tumor acidic pH microenvironment","volume":"8","author":"Wojtkowiak","year":"2011","journal-title":"Mol. Pharm."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib217","first-page":"222","article-title":"High glucose induces epithelial-mesenchymal transition and results in the migration and invasion of colorectal cancer cells","volume":"16","author":"Wu","year":"2018","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.critrevonc.2022.103796_bib218","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.taap.2019.01.016","article-title":"Estrogen down regulates COMT transcription via promoter DNA methylation in human breast cancer cells","volume":"367","author":"Wu","year":"2019","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib219","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13058-019-1096-1","article-title":"Associations between dietary patterns and the risk of breast cancer: A systematic review and meta-analysis of observational studies","volume":"21","author":"Xiao","year":"2019","journal-title":"Breast Cancer Res."},{"issue":"1","key":"10.1016\/j.critrevonc.2022.103796_bib220","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1159\/000489759","article-title":"FGFR4 links glucose metabolism and chemotherapy resistance in breast cancer","volume":"47","author":"Xu","year":"2018","journal-title":"Cell. Physiol. Biochem.: Int. J. Exp. Cell. Physiol., Biochem., Pharmacol."},{"issue":"2","key":"10.1016\/j.critrevonc.2022.103796_bib221","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1158\/0008-5472.613.65.2","article-title":"Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia","volume":"65","author":"Xu","year":"2005","journal-title":"Cancer Res."},{"issue":"1\u20132","key":"10.1016\/j.critrevonc.2022.103796_bib222","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1016\/j.ddmec.2012.10.002","article-title":"Catechol-O-methyltransferase: Characteristics, polymorphisms and role in breast cancer","volume":"9","author":"Yager","year":"2012","journal-title":"Drug Discov. Today Dis. Mech."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib223","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1007\/s12032-009-9344-3","article-title":"Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells","volume":"27","author":"Yang","year":"2010","journal-title":"Med. Oncol."},{"issue":"12","key":"10.1016\/j.critrevonc.2022.103796_bib224","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/ncb2629","article-title":"ERK1\/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect","volume":"14","author":"Yang","year":"2012","journal-title":"Nat. Cell Biol."},{"issue":"46","key":"10.1016\/j.critrevonc.2022.103796_bib225","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000008690","article-title":"Prognostic significance of metabolic enzyme pyruvate kinase M2 in breast cancer: A meta-analysis","volume":"96","author":"Yang","year":"2017","journal-title":"Medicine"},{"issue":"11","key":"10.1016\/j.critrevonc.2022.103796_bib226","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.trecan.2017.09.001","article-title":"Breast cancer: multiple subtypes within a tumor","volume":"3","author":"Yeo","year":"2017","journal-title":"Trends Cancer"},{"issue":"3","key":"10.1016\/j.critrevonc.2022.103796_bib227","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nm.3804","article-title":"The ketone metabolite \u03b2-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease","volume":"21","author":"Youm","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.critrevonc.2022.103796_bib228","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2020.109623","article-title":"Effect of polyphenols on HER2-positive breast cancer and related miRNAs: Epigenomic regulation","volume":"137","author":"Zabaleta","year":"2020","journal-title":"Food Res. Int."},{"issue":"4","key":"10.1016\/j.critrevonc.2022.103796_bib229","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.plipres.2013.08.005","article-title":"Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids","volume":"52","author":"Zaidi","year":"2013","journal-title":"Prog. Lipid Res."},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib230","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.8505","article-title":"An empirically derived definition of metabolically healthy obesity based on risk of cardiovascular and total mortality","volume":"4","author":"Zembic","year":"2021","journal-title":"JAMA Netw. Open"},{"issue":"5","key":"10.1016\/j.critrevonc.2022.103796_bib231","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1038\/aps.2018.33","article-title":"Importance of integrating nanotechnology with pharmacology and physiology for innovative drug delivery and therapy \u2013 an illustration with firsthand examples","volume":"39","author":"Zhang","year":"2018","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.critrevonc.2022.103796_bib232","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.bcp.2016.10.016","article-title":"Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation","volume":"122","author":"Zheng","year":"2016","journal-title":"Biochem. Pharmacol."}],"container-title":["Critical Reviews in Oncology\/Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1040842822002207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1040842822002207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T19:45:57Z","timestamp":1760903157000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1040842822002207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":232,"alternative-id":["S1040842822002207"],"URL":"https:\/\/doi.org\/10.1016\/j.critrevonc.2022.103796","relation":{},"ISSN":["1040-8428"],"issn-type":[{"value":"1040-8428","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cellular reprogramming, chemoresistance, and dietary interventions in breast cancer","name":"articletitle","label":"Article Title"},{"value":"Critical Reviews in Oncology\/Hematology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.critrevonc.2022.103796","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103796"}}