{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:42:42Z","timestamp":1783615362837,"version":"3.55.0"},"reference-count":176,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T00:00:00Z","timestamp":1728864000000},"content-version":"vor","delay-in-days":287,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Research in Microbial Sciences"],"published-print":{"date-parts":[[2024]]},"DOI":"10.1016\/j.crmicr.2024.100293","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T11:35:32Z","timestamp":1729078532000},"page":"100293","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Antiseptics: An expeditious third force in the prevention and management of coronavirus diseases"],"prefix":"10.1016","volume":"7","author":[{"given":"Kizito I.","family":"Okeke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7374-1641","authenticated-orcid":false,"given":"Chukwuemeka Samson","family":"Ahamefule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Obianuju O.","family":"Nnabuife","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibuchukwu N.","family":"Orabueze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian U.","family":"Iroegbu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kingsley A.","family":"Egbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2706-6141","authenticated-orcid":false,"given":"Anthony C.","family":"Ike","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0152","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ijpharm.2017.04.050","article-title":"Cyclodextrin nanosystems in oral drug delivery: a mini review","volume":"531","author":"Adeoye","year":"2017","journal-title":"Int. J. Pharm."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0104","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1001\/jamaophthalmol.2020.5810","article-title":"Conjunctival findings in patients with coronavirus disease 2019","volume":"139","author":"Agrawal","year":"2021","journal-title":"JAMa Ophthalmol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0070","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/26895293.2021.1893834","article-title":"Impact of gargling on respiratory infections","volume":"14","author":"Ahmad","year":"2021","journal-title":"All. Life"},{"key":"10.1016\/j.crmicr.2024.100293_bib0107","article-title":"COVID-19 and conjunctivitis: a meta-analysis","volume":"13","author":"Al-Namaeh","year":"2021","journal-title":"Ther. Adv. Ophthalmol."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0083","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.sdentj.2020.04.001","article-title":"Guidelines for dental care provision during the COVID-19 pandemic","volume":"32","author":"Alharbi","year":"2020","journal-title":"Saudi. Dent. J."},{"issue":"6","key":"10.1016\/j.crmicr.2024.100293_bib0076","doi-asserted-by":"crossref","first-page":"974","DOI":"10.4103\/ijo.IJO_1415_20","article-title":"All india ophthalmological society - oculoplastics association of india consensus statement on preferred practices in oculoplasty and lacrimal surgery during the COVID-19 pandemic","volume":"68","author":"Ali","year":"2020","journal-title":"Indian J. Ophthalmol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0002","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2020.582287","article-title":"The coronaviruses of animals and birds: their zoonosis, vaccines, and models for SARS-CoV and SARS-CoV2","volume":"7","author":"Alluwaimi","year":"2020","journal-title":"Front. Vet. Sci."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0179","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1016\/j.identj.2023.08.012","article-title":"The effects of antimicrobial mouthwashes on systemic disease: what is the evidence?","volume":"73","author":"Alrashdan","year":"2023","journal-title":"Int. Dent. J."},{"key":"10.1016\/j.crmicr.2024.100293_bib0167","unstructured":"American Dental Association (ADA) (2022) American Dental Association Interim Guidance for Minimizing Risk of COVID-19 Transmission. Updated April 1, 2020. http:\/\/success.ada.org\/\u223c\/media\/CPS\/Files\/COVID\/ADA_COVID_Rapid_Advice_Treat_Pts.pdf; Accessed January 27, 2022."},{"issue":"3","key":"10.1016\/j.crmicr.2024.100293_bib0059","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1007\/s40121-020-00316-3","article-title":"Povidone-iodine demonstrates rapid in vitro virucidal activity against SARS-CoV-2, the virus causing COVID-19 disease","volume":"9","author":"Anderson","year":"2020","journal-title":"Infect. Dis. Ther."},{"key":"10.1016\/j.crmicr.2024.100293_bib0066","first-page":"1","article-title":"Povidone iodine (pvp-i) oro-nasal spray: an effective shield for covid-19 protection for health care worker (HCW), for all","volume":"2021","author":"Arefin","year":"2021","journal-title":"Indian J. Otolaryngol. Head. Neck. Surg."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0110","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.ophtha.2020.08.029","article-title":"Evaluation of SARS-CoV-2 in tears of patients with moderate to severe COVID-19","volume":"128","author":"Arora","year":"2021","journal-title":"Ophthalmology."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0084","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.joen.2020.03.008","article-title":"Coronavirus disease 19 (COVID-19): implications for clinical dental care","volume":"46","author":"Ather","year":"2020","journal-title":"J. Endod."},{"key":"10.1016\/j.crmicr.2024.100293_bib0091","article-title":"Oral saliva and COVID-19","volume":"108","author":"Baghizadeh","year":"2020","journal-title":"Oral Oncol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0071","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1056\/NEJMoa2109072","article-title":"COVID-19 breakthrough infections in vaccinated Health Care Workers","volume":"385","author":"Bergwerk","year":"2021","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.crmicr.2024.100293_bib0170","doi-asserted-by":"crossref","unstructured":"Bescos R., Ashworth A., Cutler C., Brookes Z.L., Belfield L., Rodiles A., Casas-Agustench P., Farnham G., Liddle L., Burleigh M., White D., Easton C., Hickson M. (2020) Effects of chlorhexidine mouthwash on the oral microbiome. 10:5254. https:\/\/doi.org\/10.1038\/s41598-020-61912-4.","DOI":"10.1038\/s41598-020-61912-4"},{"issue":"7","key":"10.1016\/j.crmicr.2024.100293_bib0060","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/jopr.13220","article-title":"Comparison of in vitro inactivation of SARS COV-2 with hydrogen peroxide and povidone-iodine oral antiseptic rinses","volume":"29","author":"Bidra","year":"2020","journal-title":"J. Prosthodont."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0036","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003057","article-title":"Viral and bacterial interactions in the upper respiratory tract","volume":"9","author":"Bosch","year":"2013","journal-title":"PLoS. Pathog."},{"issue":"12","key":"10.1016\/j.crmicr.2024.100293_bib0157","doi-asserted-by":"crossref","first-page":"801","DOI":"10.3390\/biom9120801","article-title":"Cyclodextrins: emerging medicines of the new millennium","volume":"9","author":"Braga","year":"2019","journal-title":"Biomolecules."},{"key":"10.1016\/j.crmicr.2024.100293_bib0174","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2021.103768","article-title":"Effects of chlorhexidine mouthwash on the oral microbiome","volume":"113","author":"Brookes","year":"2021","journal-title":"J. Dent."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0169","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1016\/j.identj.2023.08.010","article-title":"Mouthwash effects on the oral microbiome: are they good, bad, or balanced?","volume":"73","author":"Brookes","year":"2023","journal-title":"Int. Dent. J."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0112","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s13756-021-01025-3","article-title":"The effect of eye protection on SARS-CoV-2 transmission: a systematic review","volume":"10","author":"Byambasuren","year":"2021","journal-title":"Antimicrob. Resist. Infect. Control"},{"issue":"9","key":"10.1016\/j.crmicr.2024.100293_bib0008","doi-asserted-by":"crossref","first-page":"311","DOI":"10.33588\/rn.7009.2020179","article-title":"Neurological complications of coronavirus and COVID-19","volume":"70","author":"Carod-Artal","year":"2020","journal-title":"Rev Neurolog"},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0149","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.3390\/jcm9041126","article-title":"COVID-19: a recommendation to examine the effect of mouthrinses with \u03b2-cyclodextrin combined with citrox in preventing infection and progression","volume":"9","author":"Carrouel","year":"2020","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0050","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1177\/0022034520967933","article-title":"Antiviral activity of reagents in mouth rinses against SARS-CoV-2","volume":"100","author":"Carrouel","year":"2021","journal-title":"J. Dent Res"},{"issue":"11","key":"10.1016\/j.crmicr.2024.100293_bib0166","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1017\/ice.2020.170","article-title":"Might hydrogen peroxide reduce the hospitalization rate and complications of SARS-CoV-2 infection?","volume":"41","author":"Caruso","year":"2020","journal-title":"Infect. Control Hosp. Epidemiol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0168","doi-asserted-by":"crossref","first-page":"4025","DOI":"10.1038\/s41598-024-54068-y","article-title":"Antibacterial mouthwash alters gut microbiome, reducing nutrient absorption and fat accumulation in Western diet-fed mice","volume":"14","author":"Carvalho","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.crmicr.2024.100293_bib0069","series-title":"StatPearls [Internet]","article-title":"Features, evaluation, and treatment of coronavirus (COVID-19)","author":"Cascella","year":"2022"},{"issue":"6","key":"10.1016\/j.crmicr.2024.100293_bib0085","doi-asserted-by":"crossref","first-page":"681","DOI":"10.4103\/jispcd.JISPCD_304_20","article-title":"Povidone-iodine solution: a potential antiseptic to minimize the risk of COVID-19? A narrative review","volume":"10","author":"Castro-Ruiz","year":"2020","journal-title":"J. Int. Soc. Prev. Community Dent."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0016","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3390\/v10020093","article-title":"MERS-CoV: understanding the latest human coronavirus threat","volume":"10","author":"Chafekar","year":"2018","journal-title":"Viruses."},{"issue":"8","key":"10.1016\/j.crmicr.2024.100293_bib0147","doi-asserted-by":"crossref","first-page":"2800","DOI":"10.3390\/nu13082800","article-title":"Hesperidin is a potential inhibitor against SARS-CoV-2 infection","volume":"13","author":"Cheng","year":"2021","journal-title":"Nutrients."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1203\/01.PDR.0000129184.87042.FC","article-title":"SARS: the first pandemic of the 21st century","volume":"56","author":"Cherry","year":"2004","journal-title":"Paediatr Res"},{"key":"10.1016\/j.crmicr.2024.100293_bib0038","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jdsr.2021.03.001","article-title":"Can povidone iodine gargle\/mouthrinse inactivate SARS-CoV-2 and decrease the risk of nosocomial and community transmission during the COVID-19 pandemic? An evidence-based update","volume":"57","author":"Chopra","year":"2021","journal-title":"Jpn. Dent. Sci. Rev."},{"issue":"10242","key":"10.1016\/j.crmicr.2024.100293_bib0111","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1016\/S0140-6736(20)31142-9","article-title":"Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis","volume":"395","author":"Chu","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.crmicr.2024.100293_bib0026","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.addr.2020.12.011","article-title":"COVID-19 vaccines: the status and perspectives in delivery points of view","volume":"170","author":"Chung","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.crmicr.2024.100293_bib0128","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1056\/NEJMsb2104756","article-title":"SARS-CoV-2 variants in patients with immunosuppression","volume":"385","author":"Corey","year":"2021","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0101","doi-asserted-by":"crossref","first-page":"e173","DOI":"10.1016\/S2666-5247(21)00040-9","article-title":"SARS-CoV-2: eye protection might be the missing key","volume":"2","author":"Coroneo","year":"2021","journal-title":"Lancet Microbe"},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0022","first-page":"157","article-title":"WHO declares COVID-19 a pandemic","volume":"91","author":"Cucinotta","year":"2020","journal-title":"Acta Biomed."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0158","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1128\/JVI.78.1.33-41.2004","article-title":"Cholesterol removal by methyl-beta-cyclodextrin inhibits poliovirus entry","volume":"78","author":"Danthi","year":"2004","journal-title":"J. Virol."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0065","doi-asserted-by":"crossref","DOI":"10.1099\/jgv.0.001578","article-title":"Effective in vitro inactivation of SARS-CoV-2 by commercially available mouthwashes","volume":"102","author":"Davies","year":"2021","journal-title":"J. Gen. Virol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0102","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.vacun.2020.09.003","article-title":"Transmission of SARS CoV-2 virus through the ocular mucosa worth taking precautions","volume":"22","author":"Dawood","year":"2021","journal-title":"Vacunas."},{"key":"10.1016\/j.crmicr.2024.100293_bib0164","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jviromet.2014.07.003","article-title":"Hydrogen peroxide inactivation of influenza virus preserves antigenic structure and immunogenicity","volume":"207","author":"Dembinski","year":"2014","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.crmicr.2024.100293_bib0086","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.3389\/fmicb.2020.01351","article-title":"Biocides and novel antimicrobial agents for the mitigation of coronaviruses","volume":"11","author":"Dev Kumar","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.tmaid.2020.101830","article-title":"SARS-CoV-2 jumping the species barrier: zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus","volume":"37","author":"Dhama","year":"2020","journal-title":"Travel. Med. Infect. Dis."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0092","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1164\/rccm.202004-1263PP","article-title":"Coughs and sneezes: their role in transmission of respiratory viral infections, including SARS-CoV-2","volume":"202","author":"Dhand","year":"2020","journal-title":"Am J Resp Crit Care Med"},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0055","first-page":"31","article-title":"The effect of 1% povidone iodine as a pre-procedural mouthrinse in 20 patients with varying degrees of oral hygiene","volume":"48","author":"Domingo","year":"1996","journal-title":"J. Philipp. Dent. Assoc."},{"key":"10.1016\/j.crmicr.2024.100293_bib0094","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.576622","article-title":"The SARS-CoV-2 spike glycoprotein biosynthesis, structure, function, and antigenicity: implications for the design of spike-based vaccine immunogens","volume":"11","author":"Duan","year":"2020","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0058","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s40121-015-0091-9","article-title":"Rapid and effective virucidal activity of povidone-iodine products against Middle East respiratory syndrome coronavirus (MERS-CoV) and modified vaccinia virus Ankara (MVA)","volume":"4","author":"Eggers","year":"2015","journal-title":"Infect. Dis. Ther."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0057","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s40121-018-0200-7","article-title":"In vitro bactericidal and virucidal efficacy of povidone-iodine gargle\/mouthwash against respiratory and oral tract pathogens","volume":"7","author":"Eggers","year":"2018","journal-title":"Infect. Dis. Ther."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0074","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s40121-019-00260-x","article-title":"Infectious disease management and control with povidone iodine","volume":"8","author":"Eggers","year":"2019","journal-title":"Infect. Dis. Ther."},{"issue":"3","key":"10.1016\/j.crmicr.2024.100293_bib0116","doi-asserted-by":"crossref","DOI":"10.1016\/j.jebdp.2021.101584","article-title":"In vivo evaluation of the virucidal efficacy of chlorhexidine and povidone-iodine mouthwashes against salivary SARS-CoV-2. A randomized-controlled clinical trial","volume":"21","author":"Elzein","year":"2021","journal-title":"J Evid-Based Dent Pract"},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0173","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0194729","article-title":"Comparison of the oral microbiome in mouthwash and whole saliva samples","volume":"13","author":"Fan","year":"2018","journal-title":"PLoS. One"},{"key":"10.1016\/j.crmicr.2024.100293_bib0001","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4939-2438-7_1","article-title":"Coronaviruses: an overview of their replication and pathogenesis","author":"Fehr","year":"2015","journal-title":"Coronaviruses. Methods Mol. Biol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0117","doi-asserted-by":"crossref","first-page":"24392","DOI":"10.1038\/s41598-021-03461-y","article-title":"Clinical evaluation of antiseptic mouth rinses to reduce salivary load of SARS-CoV-2","volume":"11","author":"Ferrer","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.crmicr.2024.100293_bib0046","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.654813","article-title":"Metabolic implications of oxidative stress and inflammatory process in SARS-CoV-2 pathogenesis: therapeutic potential of natural antioxidants","volume":"11","author":"Forcados","year":"2021","journal-title":"Front. Cell Infect. Microbiol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0072","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S1473-3099(21)00768-4","article-title":"Transmissibility of SARS-CoV-2 among fully vaccinated individuals","volume":"22","author":"Franco-Paredes","year":"2022","journal-title":"Lancet Infect. Dis."},{"issue":"9","key":"10.1016\/j.crmicr.2024.100293_bib0061","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1177\/0145561320932318","article-title":"Povidone-iodine use in sinonasal and oral cavities: a review of safety in the COVID-19 era","volume":"99","author":"Frank","year":"2020","journal-title":"Ear Nose Throat J."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0040","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1111\/idh.12555","article-title":"Could mouth rinses be an adjuvant in the treatment of SARS-CoV-2 patients? An appraisal with a systematic review","volume":"20","author":"Gandhi","year":"2021","journal-title":"Int. J. Dent. Hyg."},{"key":"10.1016\/j.crmicr.2024.100293_bib0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2020.119689","article-title":"The lord of the nanorings: cyclodextrins and the battle against SARS-CoV-2","volume":"588","author":"Garrido","year":"2020","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.crmicr.2024.100293_bib0051","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.crtox.2021.02.008","article-title":"Excessive use of disinfectants against COVID-19 posing a potential threat to living beings","volume":"2","author":"Ghafoor","year":"2021","journal-title":"Curr. Res. Toxicol."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0161","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1365-2672.2005.02664.x","article-title":"Cationic antiseptics: diversity of action under a common epithet","volume":"99","author":"Gilbert","year":"2005","journal-title":"J App Microbiol"},{"issue":"12","key":"10.1016\/j.crmicr.2024.100293_bib0136","doi-asserted-by":"crossref","DOI":"10.1098\/rsos.181303","article-title":"Screening of cytotoxic or cytostatic flavonoids with quantitative fluorescent ubiquitination-based cell cycle indicator-based cell cycle assay","volume":"5","author":"Go","year":"2018","journal-title":"R. Soc. Open. Sci."},{"issue":"10","key":"10.1016\/j.crmicr.2024.100293_bib0118","doi-asserted-by":"crossref","first-page":"3707","DOI":"10.1007\/s00784-020-03549-1","article-title":"A prospective clinical pilot study on the effects of a hydrogen peroxide mouthrinse on the intraoral viral load of SARS-CoV-2","volume":"24","author":"Gottsauner","year":"2020","journal-title":"Clin. Oral Investig."},{"issue":"6","key":"10.1016\/j.crmicr.2024.100293_bib0082","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/jpc.12232","article-title":"Recurrent anaphylaxis caused by topical povidone-iodine (Betadine)","volume":"49","author":"Gray","year":"2013","journal-title":"J. Paediatr. Child Health"},{"issue":"3","key":"10.1016\/j.crmicr.2024.100293_bib0120","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.pop.2013.06.004","article-title":"Upper respiratory infections","volume":"40","author":"Grief","year":"2013","journal-title":"Prim. Care"},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0077","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/ICU.0000000000000437","article-title":"The use of povidone-iodine in ophthalmology","volume":"29","author":"Grzybowski","year":"2018","journal-title":"Curr Opinion Ophthalmol"},{"key":"10.1016\/j.crmicr.2024.100293_bib0122","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.2147\/IDR.S177247","article-title":"Health care-associated infections - An overview","volume":"11","author":"Haque","year":"2018","journal-title":"Infect. Drug Resist"},{"issue":"12","key":"10.1016\/j.crmicr.2024.100293_bib0062","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/s41415-020-1794-1","article-title":"Povidone iodine gargle and mouthwash","volume":"228","author":"Hassandarvish","year":"2020","journal-title":"Brit Dent J"},{"issue":"8","key":"10.1016\/j.crmicr.2024.100293_bib0087","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1007\/s00784-020-03413-2","article-title":"Is the oral cavity relevant in SARS-CoV-2 pandemic?","volume":"24","author":"Herrera","year":"2020","journal-title":"Clin. Oral Investig."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0095","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.cell.2020.02.052","article-title":"SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor","volume":"181","author":"Hoffmann","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.crmicr.2024.100293_bib0145","doi-asserted-by":"crossref","DOI":"10.2217\/fvl-2020-0099","article-title":"Possible SARS-coronavirus 2 inhibitor revealed by simulated molecular docking to viral main protease and host toll-like receptor","author":"Hu","year":"2020","journal-title":"Future Virol."},{"issue":"7","key":"10.1016\/j.crmicr.2024.100293_bib0115","doi-asserted-by":"crossref","first-page":"4370","DOI":"10.1002\/jmv.26954","article-title":"Use of chlorhexidine to eradicate oropharyngeal SARS-CoV-2 in COVID-19 patients","volume":"93","author":"Huang","year":"2021","journal-title":"J. Med. Virol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0027","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.arcmed.2020.09.010","article-title":"Coronavirus disease (COVID-19): current status and prospects for drug and vaccine development","volume":"52","author":"Ita","year":"2021","journal-title":"Arch. Med. Res."},{"issue":"12","key":"10.1016\/j.crmicr.2024.100293_bib0119","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/BF02722930","article-title":"Upper respiratory tract infections","volume":"68","author":"Jain","year":"2001","journal-title":"Indian J Paediatr"},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0150","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.drudis.2015.11.017","article-title":"Cyclodextrins in pharmaceutical formulations I: structure and physicochemical properties, formation of complexes, and types of complex","volume":"21","author":"Jambhekar","year":"2016","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.crmicr.2024.100293_bib0073","series-title":"Pandemic Influenza Preparedness Action Plan of the Japanese government","year":"2007"},{"key":"10.1016\/j.crmicr.2024.100293_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109819","article-title":"Transmission of COVID-19 virus by droplets and aerosols: a critical review on the unresolved dichotomy","volume":"188","author":"Jayaweera","year":"2020","journal-title":"Environ. Res."},{"issue":"6","key":"10.1016\/j.crmicr.2024.100293_bib0142","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1111\/cbdd.13604","article-title":"Characteristics of flavonoids as potent MERS-CoV 3C-like protease inhibitors","volume":"94","author":"Jo","year":"2019","journal-title":"Chem. Biol. Drug Des."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0156","doi-asserted-by":"crossref","first-page":"eaax9318","DOI":"10.1126\/sciadv.aax9318","article-title":"Modified cyclodextrins as broad-spectrum antivirals","volume":"6","author":"Jones","year":"2020","journal-title":"Sci. Adv."},{"issue":"11","key":"10.1016\/j.crmicr.2024.100293_bib0041","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1111\/ijcp.12707","article-title":"Practical use of povidone-iodine antiseptic in the maintenance of oral health and in the prevention and treatment of common oropharyngeal infections","volume":"69","author":"Kanagalingam","year":"2015","journal-title":"Int. J. Clin. Pract."},{"issue":"3","key":"10.1016\/j.crmicr.2024.100293_bib0075","first-page":"105","article-title":"Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions, and chemical reagents","volume":"52","author":"Kariwa","year":"2004","journal-title":"Jap J Vet Res"},{"issue":"S1","key":"10.1016\/j.crmicr.2024.100293_bib0056","doi-asserted-by":"crossref","first-page":"S119","DOI":"10.1159\/000089211","article-title":"Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions and chemical reagents","volume":"212","author":"Kariwa","year":"2006","journal-title":"Dermatology"},{"issue":"9","key":"10.1016\/j.crmicr.2024.100293_bib0109","doi-asserted-by":"crossref","first-page":"977","DOI":"10.3855\/jidc.13224","article-title":"Detection of SARS-CoV-2 in the tears and conjunctival secretions of coronavirus disease 2019 patients","volume":"14","author":"Kaya","year":"2020","journal-title":"J. Infect. Dev. Ctries."},{"issue":"12","key":"10.1016\/j.crmicr.2024.100293_bib0030","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.40906","article-title":"Analysis of vaccine effectiveness against COVID-19 and emergence of Delta and other variants of concern in Utah","volume":"4","author":"Keegan","year":"2021","journal-title":"JAMa Netw. Open."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjoto.2020.102618","article-title":"Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in Covid 19 pandemic","volume":"41","author":"Khan","year":"2020","journal-title":"Am. J. Otolaryngol."},{"issue":"20","key":"10.1016\/j.crmicr.2024.100293_bib0135","doi-asserted-by":"crossref","first-page":"4712","DOI":"10.3390\/molecules25204712","article-title":"Antiangiogenic activity of flavonoids: a systematic review and meta-analysis","volume":"25","author":"Khater","year":"2020","journal-title":"Molecules."},{"issue":"S1","key":"10.1016\/j.crmicr.2024.100293_bib0079","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1017\/S0022215114002746","article-title":"Betadine has a ciliotoxic effect on ciliated human respiratory cells","volume":"129","author":"Kim","year":"2015","journal-title":"J. Laryngol. Otol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0081","doi-asserted-by":"crossref","DOI":"10.2139\/ssrn.3563092","article-title":"The use of povidone iodine nasal spray and mouthwash during the current COVID-19 pandemic may reduce cross infection and protect healthcare workers","author":"Kirk-Bayley","year":"2020","journal-title":"SSRN Electr J"},{"issue":"18","key":"10.1016\/j.crmicr.2024.100293_bib0127","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.2169\/internalmedicine.46.0104","article-title":"Can we prevent influenza-like illnesses by gargling?","volume":"46","author":"Kitamura","year":"2007","journal-title":"Intern. Med."},{"key":"10.1016\/j.crmicr.2024.100293_bib0121","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13756-015-0097-9","article-title":"Mortality related to hospital-associated infections in a tertiary hospital; repeated cross-sectional studies between 2004 and 2011","volume":"4","author":"Koch","year":"2015","journal-title":"Antimicrob. Resist. Infect. Control"},{"issue":"6","key":"10.1016\/j.crmicr.2024.100293_bib0078","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.survophthal.2018.05.002","article-title":"Povidone-iodine concentration and dosing in cataract surgery","volume":"63","author":"Koerner","year":"2018","journal-title":"Surv. Ophthalmol."},{"issue":"9","key":"10.1016\/j.crmicr.2024.100293_bib0124","first-page":"1","article-title":"Prevention of respiratory viral infections by virucidal mucosal antisepsis among medical staff and the community","volume":"45","author":"Kramar","year":"2020","journal-title":"Hyg. Med."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0043","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12915-019-0703-z","article-title":"The microbiome of the upper respiratory tract in health and disease","volume":"17","author":"Kumpitsch","year":"2019","journal-title":"BMC. Biol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0049","article-title":"Pharmaceutical assessment of polyvinylpyrrolidone (PVP): as excipient from conventional to controlled delivery systems with a spotlight on COVID-19 inhibition","volume":"60","author":"Kurakula","year":"2020","journal-title":"J. Drug Deliv. Sci. Technol."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0054","doi-asserted-by":"crossref","first-page":"579","DOI":"10.2217\/cpr.13.50","article-title":"Antiseptics in the era of bacterial resistance: a focus on povidone iodine","volume":"10","author":"Lachapelle","year":"2013","journal-title":"Clin. Pract."},{"issue":"21","key":"10.1016\/j.crmicr.2024.100293_bib0093","doi-asserted-by":"crossref","first-page":"8114","DOI":"10.3390\/ijerph17218114","article-title":"Model calculations of aerosol transmission and infection risk of COVID-19 in indoor environments","volume":"17","author":"Lelieveld","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.crmicr.2024.100293_bib0006","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1146\/annurev-virology-110615-042301","article-title":"Structure, function, and evolution of coronavirus spike proteins","volume":"3","author":"Li","year":"2016","journal-title":"Annu Rev. Virol."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0105","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1001\/jamaophthalmol.2020.5813","article-title":"Conjunctival findings in patients with coronavirus disease 2019","volume":"139","author":"Liu","year":"2021","journal-title":"JAMa Ophthalmol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0171","article-title":"Short-term effects of chlorhexidine mouthwash and listerine on oral microbiome in hospitalized patients","volume":"13","author":"Liu","year":"2023","journal-title":"Front. Cell Infect. Microbiol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0139","doi-asserted-by":"crossref","first-page":"03630","DOI":"10.1016\/j.bioorg.2020.103630","article-title":"Structural characterization, neuroprotective and hepatoprotective activities of flavonoids from the bulbs of Heleocharis dulcis","volume":"96","author":"Ma","year":"2020","journal-title":"Bioorg. Chem."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0028","first-page":"14","article-title":"Recent developments on therapeutic and diagnostic approaches for COVID-19","volume":"23","author":"Majumder","year":"2021","journal-title":"Am Assoc Pharm Sci J"},{"key":"10.1016\/j.crmicr.2024.100293_bib0067","series-title":"Based on Available Evidence up to 3 July 2020","first-page":"2020","article-title":"Povidone-iodine for disinfection of SARS-CoV-2","year":"2020"},{"key":"10.1016\/j.crmicr.2024.100293_bib0114","article-title":"Is povidone iodine mouthwash effective against SARS-CoV-2? First in vivo tests","volume":"2020","author":"Mart\u00ednez Lamas","year":"2020","journal-title":"Oral Dis."},{"issue":"8","key":"10.1016\/j.crmicr.2024.100293_bib0064","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/infdis\/jiaa471","article-title":"Virucidal efficacy of different oral rinses against severe acute respiratory syndrome coronavirus 2","volume":"222","author":"Meister","year":"2020","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.crmicr.2024.100293_bib0154","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.ijpharm.2019.01.041","article-title":"Advances of nanosystems containing cyclodextrins and their applications in pharmaceuticals","volume":"559","author":"Menezes","year":"2019","journal-title":"Int. J. Pharm."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0130","first-page":"673","article-title":"The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer","volume":"52","author":"Middleton","year":"2000","journal-title":"Pharmacol. Rev."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0175","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2334\/josnusd.16-0593","article-title":"The effects of essential oil, povidone-iodine, and chlorhexidine mouthwash on salivary nitrate\/nitrite and nitrate-reducing bacteria","volume":"59","author":"Mitsui","year":"2017","journal-title":"J. Oral Sci."},{"issue":"3","key":"10.1016\/j.crmicr.2024.100293_bib0163","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0195-6701(90)90036-N","article-title":"Effective inactivation of human immunodeficiency virus with chlorhexidine antiseptics containing detergents and alcohol","volume":"15","author":"Montefiori","year":"1990","journal-title":"J. Hosp. Infect."},{"key":"10.1016\/j.crmicr.2024.100293_bib0144","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2020.173759","article-title":"Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)","volume":"891","author":"Mouffouk","year":"2021","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0153","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/bcpt.12917","article-title":"Cyclodextrin-based formulations: a non-invasive platform for targeted drug delivery","volume":"122","author":"Muankaew","year":"2018","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"issue":"17","key":"10.1016\/j.crmicr.2024.100293_bib0146","doi-asserted-by":"crossref","first-page":"3980","DOI":"10.3390\/molecules25173980","article-title":"Natural flavonoids as potential angiotensin-converting enzyme 2 inhibitors for anti-SARS-CoV-2","volume":"25","author":"Muchtaridi","year":"2020","journal-title":"Molecules."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0013","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1055\/s-2007-976492","article-title":"Severe acute respiratory syndrome (SARS) coronavirus","volume":"28","author":"Muller","year":"2007","journal-title":"Semin Resp Crit Care Med"},{"issue":"S10","key":"10.1016\/j.crmicr.2024.100293_bib0035","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1097\/INF.0b013e3181b6d7ec","article-title":"Microbial interactions in the respiratory tract","volume":"28","author":"Murphy","year":"2009","journal-title":"Pediatr. Infect. Dis. J."},{"issue":"S1","key":"10.1016\/j.crmicr.2024.100293_bib0125","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1159\/000057722","article-title":"Prevention of respiratory infections by povidone-iodine gargle","volume":"204","author":"Nagatake","year":"2002","journal-title":"Dermatology"},{"issue":"3","key":"10.1016\/j.crmicr.2024.100293_bib0131","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1128\/CVI.13.3.319-328.2006","article-title":"The flavonoid quercetin inhibits proinflammatory cytokine (tumor necrosis factor alpha) gene expression in normal peripheral blood mononuclear cells via modulation of the NF-kappa beta system","volume":"13","author":"Nair","year":"2006","journal-title":"Clin Vaccin Immunol"},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0068","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s40463-020-00474-x","article-title":"Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework","volume":"49","author":"Naqvi","year":"2020","journal-title":"J Otolaryngol - Head Neck Surg"},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0137","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/s10517-017-3771-5","article-title":"Anti-inflammatory and analgesic activities of the complex of flavonoids from Lychnis chalcedonica L","volume":"163","author":"Nesterova","year":"2017","journal-title":"Bull. Exp. Biol. Med."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0098","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1186\/s13054-020-03120-0","article-title":"Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19","volume":"24","author":"Ni","year":"2020","journal-title":"Crit care (Lond Engl)"},{"key":"10.1016\/j.crmicr.2024.100293_bib0032","article-title":"COVID-19 vaccine acceptance in Nigeria: a rapid systematic review and meta-analysis","author":"Nnaemeka","year":"2023","journal-title":"medRxiv."},{"key":"10.1016\/j.crmicr.2024.100293_bib0007","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2021.717941","article-title":"Cross-species transmission of coronaviruses in humans and domestic mammals, what are the ecological mechanisms driving transmission, spillover, and disease emergence?","volume":"9","author":"Nova","year":"2021","journal-title":"Front. Public Health"},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0165","doi-asserted-by":"crossref","first-page":"zqaa002","DOI":"10.1093\/function\/zqaa002","article-title":"Potential role of oral rinses targeting the viral lipid envelope in SARS-CoV-2 infection","volume":"1","author":"O'Donnell","year":"2020","journal-title":"Function"},{"issue":"NP2","key":"10.1016\/j.crmicr.2024.100293_bib0108","first-page":"NP161","article-title":"Conjunctivitis as sole symptom of COVID-19: a case report and review of literature","volume":"31","author":"Ozturker","year":"2021","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0160","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.796855","article-title":"Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry","volume":"12","author":"Palacios-R\u00e1palo","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0129","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1017\/jns.2016.41","article-title":"Flavonoids: an overview","volume":"5","author":"Panche","year":"2016","journal-title":"J. Nutr. Sci."},{"issue":"13","key":"10.1016\/j.crmicr.2024.100293_bib0134","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.3390\/ijms21134620","article-title":"Effects of apigenin on RBL-2H3, RAW264.7, and HaCaT cells: anti-Allergic, anti-inflammatory, and skin-protective activities","volume":"21","author":"Park","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"S3","key":"10.1016\/j.crmicr.2024.100293_bib0039","doi-asserted-by":"crossref","first-page":"S752","DOI":"10.1111\/odi.13378","article-title":"Povidone-iodine gargle as a prophylactic intervention to interrupt the transmission of SARS-CoV-2","volume":"27","author":"Pattanshetty","year":"2021","journal-title":"Oral Dis."},{"issue":"S2","key":"10.1016\/j.crmicr.2024.100293_bib0063","doi-asserted-by":"crossref","first-page":"S192","DOI":"10.1177\/0145561320957237","article-title":"Efficacy of povidone-iodine nasal and oral antiseptic preparations against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)","volume":"100","author":"Pelletier","year":"2021","journal-title":"Ear Nose Throat J."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0088","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41368-020-0075-9","article-title":"Transmission routes of 2019-nCoV and controls in dental practice","volume":"12","author":"Peng","year":"2020","journal-title":"Int. J. Oral Sci."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0177","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01757-21","article-title":"The impact of mouthwash on the oropharyngeal microbiota of men who have sex with men: a substudy of the OMEGA trial","volume":"10","author":"Plummer","year":"2022","journal-title":"Microbiol. Spectr."},{"issue":"Pt2","key":"10.1016\/j.crmicr.2024.100293_bib0159","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1099\/vir.0.070870-0","article-title":"Role of the lipid rafts in the life cycle of canine coronavirus","volume":"96","author":"Pratelli","year":"2015","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0178","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph19073926","article-title":"Fresh look at mouthwashes \u2014What is inside and what is it for?","volume":"19","author":"Radzki","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0176","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s12903-023-02920-4","article-title":"The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic treatment: a systematic review and meta-analysis","volume":"23","author":"Ren","year":"2023","journal-title":"BMC. Oral Health"},{"issue":"9","key":"10.1016\/j.crmicr.2024.100293_bib0033","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1010876","article-title":"Shedding of infectious SARS-CoV-2 despite vaccination","volume":"18","author":"Riemersma","year":"2022","journal-title":"PLoS. Pathog."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0037","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/j.jaci.2021.02.001","article-title":"SARS-CoV-2 infection and viral load are associated with the upper respiratory tract microbiome","volume":"147","author":"Rosas-Salazar","year":"2021","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0132","article-title":"Roles of flavonoids against coronavirus infection","volume":"328","author":"Russo","year":"2020","journal-title":"Chem-Biolog Interact"},{"issue":"22","key":"10.1016\/j.crmicr.2024.100293_bib0141","doi-asserted-by":"crossref","first-page":"7940","DOI":"10.1016\/j.bmc.2010.09.035","article-title":"Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition","volume":"18","author":"Ryu","year":"2010","journal-title":"Bioorg. Med. Chem."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0018","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1002\/jmv.26553","article-title":"Evolution of SARS-CoV-2 genome from December 2019 to late March 2020: emerged haplotypes and informative Tag nucleotide variations","volume":"93","author":"Safari","year":"2020","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0099","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2020.594495","article-title":"Body localization of ACE-2: on the trail of the keyhole of SARS-CoV-2","volume":"7","author":"Salamanna","year":"2020","journal-title":"Front. Med."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0151","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.3390\/molecules23051161","article-title":"Solubility of cyclodextrins and drug\/cyclodextrin complexes","volume":"23","author":"Saokham","year":"2018","journal-title":"Molecules."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0126","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.amepre.2005.06.013","article-title":"Prevention of upper respiratory tract infections by gargling: a randomized trial","volume":"29","author":"Satomura","year":"2005","journal-title":"Am. J. Prev. Med."},{"key":"10.1016\/j.crmicr.2024.100293_bib0106","doi-asserted-by":"crossref","first-page":"e00774","DOI":"10.1016\/j.idcr.2020.e00774","article-title":"Conjunctivitis can be the only presenting sign and symptom of COVID-19","volume":"20","author":"Scalinci","year":"2020","journal-title":"IDCases."},{"issue":"3","key":"10.1016\/j.crmicr.2024.100293_bib0053","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1080\/00015458.2003.11679417","article-title":"The role of iodine in antisepsis and wound management: a reappraisal","volume":"103","author":"Selvaggi","year":"2003","journal-title":"Acta Chir. Belg."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0113","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s15010-020-01563-9","article-title":"Efficacy of commercial mouth-rinses on SARS-CoV-2 viral load in saliva: randomized control trial in Singapore","volume":"49","author":"Seneviratne","year":"2021","journal-title":"Infection"},{"issue":"21","key":"10.1016\/j.crmicr.2024.100293_bib0096","doi-asserted-by":"crossref","first-page":"11727","DOI":"10.1073\/pnas.2003138117","article-title":"Cell entry mechanisms of SARS-CoV-2","volume":"117","author":"Shang","year":"2020","journal-title":"Proc Nat Acad Sci USA"},{"key":"10.1016\/j.crmicr.2024.100293_bib0005","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jare.2020.03.005","article-title":"COVID-19 infection: origin, transmission, and characteristics of human coronaviruses","volume":"24","author":"Shereen","year":"2020","journal-title":"J. Adv. Res."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0140","doi-asserted-by":"crossref","first-page":"16127","DOI":"10.1038\/s41598-017-16336-y","article-title":"Flavonoids from Pterogyne nitens Inhibit hepatitis C virus entry","volume":"7","author":"Shimizu","year":"2017","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0034","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S1473-3099(21)00648-4","article-title":"Community transmission and viral load kinetics of the individuals in the UK: a prospective, longitudinal, cohort study","volume":"22","author":"Singanayaman","year":"2022","journal-title":"Lancet Infect. Dis."},{"issue":"8","key":"10.1016\/j.crmicr.2024.100293_bib0172","first-page":"e477","article-title":"Effect of using povidone iodine and herbal propolis antibacterial mouth on blood pressure","volume":"30","author":"Sitanaya","year":"2023","journal-title":"J. Popul. Ther. Clin. Pharmacol."},{"issue":"1","key":"10.1016\/j.crmicr.2024.100293_bib0025","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1161\/HYPERTENSIONAHA.120.15291","article-title":"ACE2 (Angiotensin-Converting Enzyme 2), COVID-19, and ACE inhibitor and Ang II (Angiotensin II) receptor blocker use during the pandemic: the pediatric perspective","volume":"76","author":"South","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.crmicr.2024.100293_bib0133","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ejmech.2017.09.001","article-title":"Anti-inflammatory effects of flavonoids in neurodegenerative disorders","volume":"153","author":"Spagnuolo","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.crmicr.2024.100293_bib0052","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/1743-422X-6-124","article-title":"Mechanisms of the action of povidone-iodine against human and avian influenza A viruses: its effects on hemagglutination and sialidase activities","volume":"6","author":"Sriwilaijaroen","year":"2009","journal-title":"Virol. J."},{"issue":"6","key":"10.1016\/j.crmicr.2024.100293_bib0045","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1007\/s10930-020-09935-8","article-title":"Role of oxidative stress on SARS-CoV (SARS) and SARS-CoV-2 (COVID-19) infection: a review","volume":"39","author":"Suhail","year":"2020","journal-title":"Protein J."},{"key":"10.1016\/j.crmicr.2024.100293_bib0103","doi-asserted-by":"crossref","unstructured":"Sun C.B., Wang Y.Y., Liu G.H., Liu Z. (2020) Role of the eye in transmitting human coronavirus: what we know and what we do not know. Front Public Health 8:155. https:\/\/doi.org\/10.3389\/fpubh.2020.00155.","DOI":"10.3389\/fpubh.2020.00155"},{"key":"10.1016\/j.crmicr.2024.100293_bib0011","doi-asserted-by":"crossref","first-page":"578","DOI":"10.3389\/fvets.2020.00578","article-title":"COVID-19 in human, animal, and environment: a review","volume":"7","author":"Swelum","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.crmicr.2024.100293_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.173890","article-title":"A review of potential suggested drugs for coronavirus disease (COVID-19) treatment","volume":"895","author":"Tarighi","year":"2021","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0138","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109004","article-title":"Flavonoids showed anticancer effects on the ovarian cancer cells: involvement of reactive oxygen species, apoptosis, cell cycle and invasion","volume":"116","author":"Tavsan","year":"2019","journal-title":"Biomed. PharmacOther"},{"issue":"S1","key":"10.1016\/j.crmicr.2024.100293_bib0162","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.4103\/jpbs.JPBS_162_20","article-title":"Chlorhexidine: an elixir for periodontics","volume":"12","author":"Thangavelu","year":"2020","journal-title":"J. Pharm. Bioallied. Sci."},{"issue":"15","key":"10.1016\/j.crmicr.2024.100293_bib0089","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1093\/cid\/ciaa149","article-title":"Consistent detection of 2019 novel coronavirus in saliva","volume":"71","author":"To","year":"2020","journal-title":"Clin. Infect. Dis."},{"issue":"7","key":"10.1016\/j.crmicr.2024.100293_bib0047","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.scib.2020.12.025","article-title":"Inactivating SARS-CoV-2 by electrochemical oxidation","volume":"66","author":"Tu","year":"2021","journal-title":"Sci Bull"},{"key":"10.1016\/j.crmicr.2024.100293_bib0031","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1038\/s41467-021-23938-8","article-title":"Controlling the pandemic during the SARS-CoV-2 vaccination rollout","volume":"12","author":"Viana","year":"2021","journal-title":"Nat Comm"},{"key":"10.1016\/j.crmicr.2024.100293_bib0042","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.micpath.2015.09.009","article-title":"Periodontal-disease-associated biofilm: a reservoir for pathogens of medical importance","volume":"94","author":"Vieira Colombo","year":"2016","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.crmicr.2024.100293_bib0023","series-title":"Coronavirus Disease (COVID 19) Pandemic","year":"2021"},{"issue":"2","key":"10.1016\/j.crmicr.2024.100293_bib0010","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.cell.2020.02.058","article-title":"Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein","volume":"181","author":"Walls","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.crmicr.2024.100293_bib0003","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-0716-0900-2_1","article-title":"Coronaviruses: an updated overview of their replication and pathogenesis","author":"Wang","year":"2020","journal-title":"Coronaviruses. Methods Mol. Biol.."},{"key":"10.1016\/j.crmicr.2024.100293_bib0024","unstructured":"World Health Organization Data (2024) WHO COVID-19 dashboard. https:\/\/data.who.int\/dashboards\/covid19\/ Accessed June 17, 2024."},{"key":"10.1016\/j.crmicr.2024.100293_bib0123","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2147\/JMDH.S254964","article-title":"Health professionals oral health knowledge and practice: unleashing the hidden challenges","volume":"13","author":"Yimenu","year":"2020","journal-title":"J. Multidiscip. Healthc."},{"issue":"20","key":"10.1016\/j.crmicr.2024.100293_bib0090","doi-asserted-by":"crossref","first-page":"e195","DOI":"10.3346\/jkms.2020.35.e195","article-title":"Clinical significance of a high SARS-CoV-2 viral load in the saliva","volume":"35","author":"Yoon","year":"2020","journal-title":"J. Korean Med. Sci."},{"issue":"8","key":"10.1016\/j.crmicr.2024.100293_bib0148","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1002\/ddr.21815","article-title":"Potential antiviral activity of isorhamnetin against SARS-CoV-2 spike pseudotyped virus in vitro","volume":"82","author":"Zhan","year":"2021","journal-title":"Drug Dev. Res."},{"issue":"5","key":"10.1016\/j.crmicr.2024.100293_bib0143","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/jmv.25707","article-title":"Potential interventions for novel coronavirus in China: a systematic review","volume":"92","author":"Zhang","year":"2020","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.crmicr.2024.100293_bib0048","doi-asserted-by":"crossref","first-page":"38669","DOI":"10.1038\/srep38669","article-title":"Use of polyvinylpyrrolidone-iodine solution for sterilisation and preservation improves mechanical properties and osteogenesis of allografts","volume":"6","author":"Zhao","year":"2016","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0100","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.jtos.2020.06.007","article-title":"ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection","volume":"18","author":"Zhou","year":"2020","journal-title":"Ocul Surface"},{"issue":"8","key":"10.1016\/j.crmicr.2024.100293_bib0017","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"Tan W & China Novel Coronavirus Investigating and Research Team (2020) A novel coronavirus from patients with pneumonia in China","volume":"382","author":"Zhu","year":"2019","journal-title":"N. Engl. J. Med."},{"issue":"12","key":"10.1016\/j.crmicr.2024.100293_bib0044","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1056\/NEJMc2001737","article-title":"SARS-CoV-2 viral load in upper respiratory specimens of infected patients","volume":"382","author":"Zou","year":"2020","journal-title":"N. Engl. J. Med."},{"issue":"9997","key":"10.1016\/j.crmicr.2024.100293_bib0014","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S0140-6736(15)60454-8","article-title":"Middle East respiratory syndrome","volume":"386","author":"Zumla","year":"2015","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.crmicr.2024.100293_bib0097","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1136\/jclinpath-2020-206788","article-title":"Is FURIN gene expression in salivary glands related to SARS-CoV-2 infectivity through saliva?","volume":"74","author":"Zupin","year":"2021","journal-title":"J. Clin. Pathol."},{"issue":"8","key":"10.1016\/j.crmicr.2024.100293_bib0015","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/nrmicro.2016.81","article-title":"SARS and MERS: recent insights into emerging coronaviruses","volume":"14","author":"de Wit","year":"2016","journal-title":"Nat. Rev. Microbiol."}],"container-title":["Current Research in Microbial Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666517424000762?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666517424000762?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T05:23:31Z","timestamp":1733203411000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666517424000762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":176,"alternative-id":["S2666517424000762"],"URL":"https:\/\/doi.org\/10.1016\/j.crmicr.2024.100293","relation":{},"ISSN":["2666-5174"],"issn-type":[{"value":"2666-5174","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antiseptics: An expeditious third force in the prevention and management of coronavirus diseases","name":"articletitle","label":"Article Title"},{"value":"Current Research in Microbial Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crmicr.2024.100293","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"100293"}}