{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:45:50Z","timestamp":1772120750153,"version":"3.50.1"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["ecco-jccjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Crohn's and Colitis"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.crohns.2014.05.010","type":"journal-article","created":{"date-parts":[[2014,6,20]],"date-time":"2014-06-20T10:57:56Z","timestamp":1403261876000},"page":"1464-1470","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":81,"title":["Combination of oral antibiotics may be effective in severe pediatric ulcerative colitis: A preliminary report"],"prefix":"10.1093","volume":"8","author":[{"given":"Dan","family":"Turner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arie","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaija-Leena","family":"Kolho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron","family":"Shaoul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oren","family":"Ledder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"issue":"1","key":"10.1016\/j.crohns.2014.05.010_bb0005","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/1574-6968.12111","article-title":"Implications of the human microbiome in inflammatory bowel diseases","volume":"342","author":"Bakhtiar","year":"2013","journal-title":"FEMS Microbiol Lett"},{"issue":"10","key":"10.1016\/j.crohns.2014.05.010_bb0010","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1002\/ibd.22860","article-title":"Alterations in the gut microbiome of children with severe ulcerative colitis","volume":"18","author":"Michail","year":"2012","journal-title":"Inflamm Bowel Dis"},{"issue":"6","key":"10.1016\/j.crohns.2014.05.010_bb0015","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.3892\/etm.2012.718","article-title":"Meta-analysis of broad-spectrum antibiotic therapy in patients with active inflammatory bowel disease","volume":"4","author":"Wang","year":"2012","journal-title":"Exp Ther Med"},{"issue":"8","key":"10.1016\/j.crohns.2014.05.010_bb0020","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1038\/ajg.2010.84","article-title":"Newly developed antibiotic combination therapy for ulcerative colitis: a double-blind placebo-controlled multicenter trial","volume":"105","author":"Ohkusa","year":"2010","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"10.1016\/j.crohns.2014.05.010_bb0025","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1080\/00365520510023648","article-title":"Effectiveness of antibiotic combination therapy in patients with active ulcerative colitis: a randomized, controlled pilot trial with long-term follow-up","volume":"40","author":"Ohkusa","year":"2005","journal-title":"Scand J Gastroenterol"},{"issue":"3","key":"10.1016\/j.crohns.2014.05.010_bb0030","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1159\/000321811","article-title":"Antibiotic combination therapy for steroid withdrawal in steroid-dependent ulcerative colitis","volume":"83","author":"Terao","year":"2011","journal-title":"Digestion"},{"issue":"1","key":"10.1016\/j.crohns.2014.05.010_bb0035","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/gut.52.1.79","article-title":"Induction of experimental ulcerative colitis by Fusobacterium varium isolated from colonic mucosa of patients with ulcerative colitis","volume":"52","author":"Ohkusa","year":"2003","journal-title":"Gut"},{"issue":"12","key":"10.1016\/j.crohns.2014.05.010_bb0040","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1136\/gut.26.12.1380","article-title":"Double blind controlled trial of oral vancomycin as adjunctive treatment in acute exacerbations of idiopathic colitis","volume":"26","author":"Dickinson","year":"1985","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.crohns.2014.05.010_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.MPG.0000163736.30261.82","article-title":"Inflammatory bowel disease in children and adolescents: recommendations for diagnosis \u2014 the Porto criteria","volume":"41","year":"2005","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"2","key":"10.1016\/j.crohns.2014.05.010_bb0050","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1053\/j.gastro.2007.05.029","article-title":"Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter study","volume":"133","author":"Turner","year":"2007","journal-title":"Gastroenterology"},{"issue":"8","key":"10.1016\/j.crohns.2014.05.010_bb0055","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1002\/ibd.20867","article-title":"Appraisal of the pediatric ulcerative colitis activity index (PUCAI)","volume":"15","author":"Turner","year":"2009","journal-title":"Inflamm Bowel Dis"},{"issue":"3","key":"10.1016\/j.crohns.2014.05.010_bb0060","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1136\/gut.2007.136481","article-title":"Severe paediatric ulcerative colitis: incidence, outcomes and optimal timing for second-line therapy","volume":"57","author":"Turner","year":"2008","journal-title":"Gut"},{"issue":"7","key":"10.1016\/j.crohns.2014.05.010_bb0065","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1053\/j.gastro.2010.02.047","article-title":"Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response","volume":"138","author":"Turner","year":"2010","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.crohns.2014.05.010_bb0070","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3748\/wjg.v20.i2.509","article-title":"Long-term follow-up of ulcerative colitis patients treated on the basis of their cytomegalovirus antigen status","volume":"20","author":"Inokuchi","year":"2014","journal-title":"World J Gastroenterol"},{"issue":"12","key":"10.1016\/j.crohns.2014.05.010_bb0075","doi-asserted-by":"crossref","first-page":"3463","DOI":"10.1111\/j.1572-0241.2001.05359.x","article-title":"Cryptosporidium parvum in intestinal mucosal biopsies from patients with inflammatory bowel disease","volume":"96","author":"Chen","year":"2001","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"10.1016\/j.crohns.2014.05.010_bb0080","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/ibd.22964","article-title":"Clostridium difficile infection in the inflammatory bowel disease patient","volume":"19","author":"Berg","year":"2013","journal-title":"Inflamm Bowel Dis"},{"issue":"6","key":"10.1016\/j.crohns.2014.05.010_bb0085","doi-asserted-by":"crossref","first-page":"e63686","DOI":"10.1371\/journal.pone.0063686","article-title":"Characterization of adherent bacteroidales from intestinal biopsies of children and young adults with inflammatory bowel disease","volume":"8","author":"Zitomersky","year":"2013","journal-title":"PLoS ONE"},{"issue":"10","key":"10.1016\/j.crohns.2014.05.010_bb0090","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1136\/gut.27.10.1210","article-title":"Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis","volume":"27","author":"Chapman","year":"1986","journal-title":"Gut"},{"issue":"9","key":"10.1016\/j.crohns.2014.05.010_bb0095","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1080\/003655201750305503","article-title":"A prospective randomized controlled trial of intravenous ciprofloxacin as an adjunct to corticosteroids in acute, severe ulcerative colitis","volume":"36","author":"Mantzaris","year":"2001","journal-title":"Scand J Gastroenterol"},{"issue":"1","key":"10.1016\/j.crohns.2014.05.010_bb0100","first-page":"43","article-title":"Intravenous tobramycin and metronidazole as an adjunct to corticosteroids in acute, severe ulcerative colitis","volume":"89","author":"Mantzaris","year":"1994","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"10.1016\/j.crohns.2014.05.010_bb0105","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1365-2036.1990.tb00456.x","article-title":"The efficacy of tobramycin in the treatment of ulcerative colitis","volume":"4","author":"Burke","year":"1990","journal-title":"Aliment Pharmacol Ther"},{"issue":"5","key":"10.1016\/j.crohns.2014.05.010_bb0110","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/S0016-5085(98)70076-9","article-title":"Long-term treatment of ulcerative colitis with ciprofloxacin: a prospective, double-blind, placebo-controlled study","volume":"115","author":"Turunen","year":"1998","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.crohns.2014.05.010_bb0115","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1023\/A:1026648812439","article-title":"Rifaximin in patients with moderate or severe ulcerative colitis refractory to steroid-treatment: a double-blind, placebo-controlled trial","volume":"44","author":"Gionchetti","year":"1999","journal-title":"Dig Dis Sci"},{"issue":"3","key":"10.1016\/j.crohns.2014.05.010_bb0120","first-page":"454","article-title":"A prospective randomized controlled trial of oral ciprofloxacin in acute ulcerative colitis","volume":"92","author":"Mantzaris","year":"1997","journal-title":"Am J Gastroenterol"},{"issue":"11","key":"10.1016\/j.crohns.2014.05.010_bb0125","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.cgh.2013.04.049","article-title":"Endoscopic and clinical variables that predict sustained remission in children with ulcerative colitis treated with infliximab","volume":"11","author":"Turner","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"10","key":"10.1016\/j.crohns.2014.05.010_bb0130","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.cgh.2009.06.024","article-title":"A systematic prospective comparison of noninvasive disease activity indices in ulcerative colitis","volume":"7","author":"Turner","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.crohns.2014.05.010_bb0135","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1365-2036.1993.tb00084.x","article-title":"Oral tobramycin in ulcerative colitis: effect on maintenance of remission","volume":"7","author":"Lobo","year":"1993","journal-title":"Aliment Pharmacol Ther"},{"issue":"3","key":"10.1016\/j.crohns.2014.05.010_bb0140","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/MPG.0b013e3182662233","article-title":"Management of pediatric ulcerative colitis: joint ECCO and ESPGHAN evidence-based consensus guidelines","volume":"55","author":"Turner","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"4","key":"10.1016\/j.crohns.2014.05.010_bb0145","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/ajg.2010.481","article-title":"Consensus for managing acute severe ulcerative colitis in children: a systematic review and joint statement from ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN","volume":"106","author":"Turner","year":"2011","journal-title":"Am J Gastroenterol"}],"container-title":["Journal of Crohn's and Colitis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1873994614001834?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1873994614001834?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/ecco-jcc\/article-pdf\/8\/11\/1464\/1021049\/8-11-1464.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,11]],"date-time":"2019-08-11T15:40:55Z","timestamp":1565538055000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ecco-jcc\/article-lookup\/doi\/10.1016\/j.crohns.2014.05.010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":29,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S1873994614001834"],"URL":"https:\/\/doi.org\/10.1016\/j.crohns.2014.05.010","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718477355.793514457","asserted-by":"object"}]},"ISSN":["1873-9946"],"issn-type":[{"value":"1873-9946","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Combination of oral antibiotics may be effective in severe pediatric ulcerative colitis: A preliminary report","name":"articletitle","label":"Article Title"},{"value":"Journal of Crohn's and Colitis","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.crohns.2014.05.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}