{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:41:01Z","timestamp":1762940461627,"version":"3.45.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"vor","delay-in-days":59,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["NR 7767\/3-2004"],"award-info":[{"award-number":["NR 7767\/3-2004"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Research in Physiology"],"published-print":{"date-parts":[[2021]]},"DOI":"10.1016\/j.crphys.2021.02.004","type":"journal-article","created":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T15:36:46Z","timestamp":1615131406000},"page":"73-79","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Ventilatory constraint is more severe in walking than cycling in patients with COPD"],"prefix":"10.1016","volume":"4","author":[{"given":"Jan","family":"Chlumsk\u00fd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ond\u0159ej","family":"Zindr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.crphys.2021.02.004_bib1","doi-asserted-by":"crossref","first-page":"1900164","DOI":"10.1183\/13993003.00164-2019","article-title":"Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019","volume":"53","author":"Singh","year":"2019","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.crphys.2021.02.004_bib2","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1164\/ajrccm.158.5.9804004","article-title":"Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease","volume":"158","author":"O\u2019Donnell","year":"1998","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.crphys.2021.02.004_bib3","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1183\/09031936.03.00034603","article-title":"The 6-min walk distance: change over time and value as a predictor of survival in severe COPD","volume":"23","author":"Pinto-Plata","year":"2004","journal-title":"Eur. Respir. J."},{"issue":"5","key":"10.1016\/j.crphys.2021.02.004_bib4","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1164\/rccm.200407-961OC","article-title":"Effect of bronchoscopic lung volume reduction on dynamic hyperinflation and exercise in emphysema","volume":"171","author":"Hopkinson","year":"2005","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"5","key":"10.1016\/j.crphys.2021.02.004_bib5","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1152\/jappl.2000.88.5.1715","article-title":"Ventilatory and metabolic adaptations to walking and cycling in patients with COPD","volume":"88","author":"Palange","year":"2000","journal-title":"J.\u00a0Appl. Physiol."},{"issue":"3","key":"10.1016\/j.crphys.2021.02.004_bib6","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1183\/09031936.02.02092001","article-title":"Physiological responses to the 6-min walk test in patients with chronic obstructive pulmonary disease","volume":"20","author":"Troosters","year":"2002","journal-title":"Eur. Respir. J."},{"issue":"3","key":"10.1016\/j.crphys.2021.02.004_bib7","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1378\/chest.126.3.766","article-title":"Physiologic responses to incremental and self-paced exercise in COPD: a comparison of three tests","volume":"126","author":"Turner","year":"2004","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.crphys.2021.02.004_bib8","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1183\/09031936.05.00034805","article-title":"Standardisation of spirometry","volume":"26","author":"Miller","year":"2005","journal-title":"Eur. Respir. J."},{"issue":"3","key":"10.1016\/j.crphys.2021.02.004_bib9","first-page":"511","article-title":"Standardisation of the measurement of lung volumes","volume":"26","author":"Wanger","year":"2005","journal-title":"Eur Respir J Off J Eur Soc Clin Respir Physiol"},{"issue":"4","key":"10.1016\/j.crphys.2021.02.004_bib10","first-page":"720","article-title":"Standardisation of the single-breath determination of carbon monoxide uptake in the lung","volume":"26","author":"Macintyre","year":"2005","journal-title":"Eur Respir J Off J Eur Soc Clin Respir Physiol"},{"issue":"Suppl.16","key":"10.1016\/j.crphys.2021.02.004_bib11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1183\/09041950.005s1693","article-title":"Lung volumes and forced ventilaroty flows","volume":"6","author":"Quanjer","year":"1993","journal-title":"Eur. Respir. J."},{"issue":"4","key":"10.1016\/j.crphys.2021.02.004_bib12","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1164\/rccm.166.4.518","article-title":"ATS\/ERS statement on respiratory muscle testing","volume":"166","author":"Gibson","year":"2002","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"5","key":"10.1016\/j.crphys.2021.02.004_bib13","first-page":"696","article-title":"Maximal respiratory pressures: normal values and relationship to age and sex","volume":"99","author":"Black","year":"1969","journal-title":"Am. Rev. Respir. Dis."},{"issue":"6","key":"10.1016\/j.crphys.2021.02.004_bib14","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1164\/ajrccm.162.6.9912053","article-title":"Noninvasive assessment of inspiratory muscle function during exercise","volume":"162","author":"Hayot","year":"2000","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"8","key":"10.1016\/j.crphys.2021.02.004_bib15","first-page":"783","article-title":"The six-minute walk test","volume":"48","author":"Enright","year":"2003","journal-title":"Respir. Care"},{"issue":"6","key":"10.1016\/j.crphys.2021.02.004_bib16","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1183\/09031936.00150314","article-title":"An official European Respiratory Society\/American Thoracic Society Technical Standard: field walking tests in chronic respiratory disease","volume":"44","author":"Holland","year":"2014","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.crphys.2021.02.004_bib17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1164\/rccm.167.2.211","article-title":"ATS\/ACCP Statement on cardiopulmonary exercise testing","volume":"167","author":"Weisman","year":"2003","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"141","key":"10.1016\/j.crphys.2021.02.004_bib18","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1183\/16000617.0054-2016","article-title":"Exertional dyspnoea in COPD: the clinical utility of cardiopulmonary exercise testing","volume":"25","author":"O\u2019Donnell","year":"2016","journal-title":"Eur. Respir. Rev."},{"issue":"100","key":"10.1016\/j.crphys.2021.02.004_bib19","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1183\/09059180.00010004","article-title":"Exercise and dyspnoea in COPD","volume":"15","author":"Calverley","year":"2006","journal-title":"Eur. Respir. Rev."},{"key":"10.1016\/j.crphys.2021.02.004_bib20","first-page":"240","article-title":"Non-invasive assessment of respiratory muscle function and its relationship to exercise tolerance in patients with chronic obstructive pulmonary disease","volume":"34","author":"Chlumsky","year":"2006","journal-title":"J.\u00a0Int. Med. Res."},{"issue":"6","key":"10.1016\/j.crphys.2021.02.004_bib21","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1183\/09031936.01.00057801","article-title":"Breathing pattern and gas exchange at peak exercise in COPD patients with and without tidal flow limitation at rest","volume":"17","author":"D\u00edaz","year":"2001","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.crphys.2021.02.004_bib22","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1152\/japplphysiol.00301.2014","article-title":"Limitation in tidal volume expansion partially determines the intensity of physical activity in COPD","volume":"118","author":"Kortianou","year":"2015","journal-title":"J.\u00a0Appl. Physiol."},{"issue":"6","key":"10.1016\/j.crphys.2021.02.004_bib23","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1164\/rccm.200812-1873OC","article-title":"Daily physical activity in patients with chronic obstructive pulmonary disease is mainly associated with dynamic hyperinflation","volume":"180","author":"Garcia-Rio","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.crphys.2021.02.004_bib24","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1249\/00005768-198021000-00004","article-title":"Cardiovascular, metabolic, and ventilatory responses of women to equivalent cycle ergometer and treadmill exercise","volume":"12","author":"Miles","year":"1980","journal-title":"Med. Sci. Sports Exerc."},{"issue":"1","key":"10.1016\/j.crphys.2021.02.004_bib25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00008483-199801000-00003","article-title":"Analysis of the metabolic and ventilatory response to self-paced 12-minute treadmill walking in patients with severe chronic obstructive pulmonary disease","volume":"18","author":"Baarends","year":"1998","journal-title":"J\u00a0Cardiopulm Rehabil"},{"issue":"5","key":"10.1016\/j.crphys.2021.02.004_bib26","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1164\/ajrccm.164.5.2012122","article-title":"Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease","volume":"164","author":"O\u2019Donnell","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.crphys.2021.02.004_bib27","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1164\/ajrccm.156.1.9608113","article-title":"Reliability of inspiratory capacity for estimating end-expiratory lung volume changes during exercise in","volume":"156","author":"Yan","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"2","key":"10.1016\/j.crphys.2021.02.004_bib28","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1378\/chest.116.2.488","article-title":"Emerging concepts in the evaluation of ventilatory limitation during exercise: the exercise tidal flow-volume loop","volume":"116","author":"Johnson","year":"1999","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.crphys.2021.02.004_bib29","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1136\/thx.48.1.33","article-title":"Effect of arterial oxygen desaturation on six minute walk distance, perceived effort, and perceived breathlessness in patients with airflow limitation","volume":"48","author":"Mak","year":"1993","journal-title":"Thorax"},{"issue":"5","key":"10.1016\/j.crphys.2021.02.004_bib30","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1378\/chest.123.5.1401","article-title":"6-Minute walk testing is more sensitive than maximal incremental cycle testing for detecting oxygen desaturation in patients with COPD","volume":"123","author":"Poulain","year":"2003","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.crphys.2021.02.004_bib31","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1164\/ajrccm.163.6.2003172","article-title":"Inspiratory capacity, dynamic hyperinflation, breathlessness, and exercise performance during the 6-minute-walk test in chronic obstructive pulmonary disease","volume":"163","author":"Marin","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."}],"container-title":["Current Research in Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665944121000080?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665944121000080?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:37:32Z","timestamp":1762940252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2665944121000080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":31,"alternative-id":["S2665944121000080"],"URL":"https:\/\/doi.org\/10.1016\/j.crphys.2021.02.004","relation":{},"ISSN":["2665-9441"],"issn-type":[{"type":"print","value":"2665-9441"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ventilatory constraint is more severe in walking than cycling in patients with COPD","name":"articletitle","label":"Article Title"},{"value":"Current Research in Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crphys.2021.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}