{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:55:33Z","timestamp":1791341733157,"version":"4.3.1"},"reference-count":28,"publisher":"MathDoc\/Centre Mersenne","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>\n                    Un test de diagnostic rapide par bandelette (RDT), qui d\u00e9tecte l'antig\u00e8ne F1 de\n                    <jats:italic>Yersinia pestis<\/jats:italic>\n                    , a \u00e9t\u00e9 appliqu\u00e9 r\u00e9cemment sur les restes de dix-huit individus exhum\u00e9s de quatre site du Sud-Est de la France, correspondant \u00e0 des s\u00e9pultures de pestif\u00e9r\u00e9s contemporains des XVI\n                    <jats:sup>e<\/jats:sup>\n                    , XVII\n                    <jats:sup>e<\/jats:sup>\n                    et XVIII\n                    <jats:sup>e<\/jats:sup>\n                    si\u00e8cles. L'antig\u00e8ne F1 de\n                    <jats:italic>Y. pestis<\/jats:italic>\n                    a \u00e9t\u00e9 d\u00e9tect\u00e9 dans les restes de douze individus sur dix-huit test\u00e9s (67%). Bien entendu, des t\u00e9moins n\u00e9gatifs ont \u00e9t\u00e9 utilis\u00e9s et ont tous confirm\u00e9 leur n\u00e9gativit\u00e9 \u00e0 l'antig\u00e8ne pesteux (100%). Les r\u00e9sultats obtenus d\u00e9montrent que le seuil de d\u00e9tection du RDT peste (0,5 ng\/ml) est suffisant pour garantir une premi\u00e8re diagnose r\u00e9trospective de l'infection pesteuse, m\u00eame sur les restes humains anciens, t\u00e9moignant \u00e0 la fois de la grande sensibilit\u00e9 et de la haute sp\u00e9cificit\u00e9 du test. L'identification de la nature pesteuse de l'infection a eu lieu, en aveugle, en utilisant deux techniques diff\u00e9rentes (RDT et \u00ab PCR suicide \u00bb). La double confirmation de la cause du d\u00e9c\u00e8s a \u00e9t\u00e9 obtenue en identifiant l'antig\u00e8ne F1 de\n                    <jats:italic>Y. pestis<\/jats:italic>\n                    ainsi que les g\u00e8nes\n                    <jats:italic>Y. pestis<\/jats:italic>\n                    pla et gplD, ce qui nous nous permet d'\u00e9mettre avec certitude un diagnostic sur l'\u00e9tiologie de la maladie.\n                  <\/jats:p>","DOI":"10.1016\/j.crvi.2007.07.007","type":"journal-article","created":{"date-parts":[[2007,9,8]],"date-time":"2007-09-08T07:19:13Z","timestamp":1189235953000},"page":"747-754","source":"Crossref","is-referenced-by-count":29,"title":["D\u00e9tection de l'antig\u00e8ne F1 de Yersinia pestis dans les restes humains anciens \u00e0 l'aide d'un test de diagnostic rapide"],"prefix":"10.5802","volume":"330","author":[{"given":"Raffaella","family":"Bianucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lila","family":"Rahalison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ezio","family":"Ferroglio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma Rabino","family":"Massa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Signoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3842","published-online":{"date-parts":[[2007,9,7]]},"reference":[{"issue":"6","key":"key2025102316284122093_1","first-page":"511","article-title":"\u00c9pid\u00e9mie de peste pulmonaire dans un camp minier de la r\u00e9publique d\u00e9mocratique du Congo : le r\u00e9veil brutal d'un vieux fl\u00e9au","volume":"65","author":"Bertherat, E.","year":"2005","unstructured":"[1] Bertherat, E.; Lamine, K.M.; Forment, P.; Thullier, P.; Mondonge, V.; Mitifu, A.; Rahalison, L. \u00c9pid\u00e9mie de peste pulmonaire dans un camp minier de la r\u00e9publique d\u00e9mocratique du Congo : le r\u00e9veil brutal d'un vieux fl\u00e9au, Med. Trop., Volume 65 (2005) no. 6, pp. 511-514","journal-title":"Med. Trop."},{"key":"key2025102316284122093_2","article-title":"Plague Manual: Epidemiology, Distribution, Surveillance and Control","author":"World Health Organization","unstructured":"[2] World Health Organization Plague Manual: Epidemiology, Distribution, Surveillance and Control http:\/\/www.who.int\/emc (WHO\/CDS\/EDC\/99.2, 2000)"},{"key":"key2025102316284122093_3","article-title":"Plague and others <span class=\"italique\">Yersinia<\/span> infections","author":"Dennis, D.T.","unstructured":"[3] Dennis, D.T.; Campbell, G.L. Plague and others Yersinia infections http:\/\/www.mheducation.com\/HOL2_chapters\/HOL_chapters\/chapter162 (in: Harrisons' Online, Part 7, Section 6, Chapter 162, 2001)"},{"key":"key2025102316284122093_4","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S1631-0691(02)01493-2","article-title":"La peste","volume":"325","author":"Carniel, E.","year":"2002","unstructured":"[4] Carniel, E. La peste, C. R. Biologies, Volume 325 (2002), pp. 851-853","journal-title":"C. R. Biologies"},{"issue":"9353","key":"key2025102316284122093_5","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0140-6736(03)12270-2","article-title":"Development and testing of a rapid diagnostic test for bubonic and pneumonic plague","volume":"361","author":"Chanteau, S.","year":"2003","unstructured":"[5] Chanteau, S.; Rahalison, L.; Ralafiarisoa, L.; Foulon, J.; Ratsitorahina, M.; Ratsifasoamanana, M.; Carniel, E.; Nato, F. Development and testing of a rapid diagnostic test for bubonic and pneumonic plague, Lancet, Volume 361 (2003) no. 9353, pp. 211-216","journal-title":"Lancet"},{"key":"key2025102316284122093_6","first-page":"231","article-title":"Utilisation du <span class=\"italique\">Rapid Diagnostic Test<\/span> pour la d\u00e9tection de <span class=\"italique\">Yersinia pestis<\/span> dans des restes humains anciens : r\u00e9sultats pr\u00e9liminaires","author":"Bianucci, R.","year":"2007","unstructured":"[6] Bianucci, R.; Chanteau, S.; Rahalison, L.; Savoia, D.; Signoli, M.; Rabino Massa, E. 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Signoli, \u00c9tudes anthropologiques des crises d\u00e9mographiques en contexte \u00e9pid\u00e9mique : Aspects pal\u00e9o- et biod\u00e9mographiques de la peste en Provence, Br. Archaeol. Reports Int. Ser., Archaeopress, Oxford, Royaume-Uni, 2006, n\u00b01515"},{"key":"key2025102316284122093_13","doi-asserted-by":"crossref","first-page":"12637","DOI":"10.1073\/pnas.95.21.12637","article-title":"Detection of 400-year old <span class=\"italique\">Yersinia pestis<\/span> DNA in human dental pulp. An approach to diagnosis of ancient septicemia","volume":"95","author":"Drancourt, M.","year":"1998","unstructured":"[13] Drancourt, M.; Aboudharam, G.; Signoli, M.; Dutour, O.; Raoult, D. Detection of 400-year old Yersinia pestis DNA in human dental pulp. An approach to diagnosis of ancient septicemia, Proc. Natl Acad. Sci. USA, Volume 95 (1998), pp. 12637-12640","journal-title":"Proc. Natl Acad. Sci. 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Attempted PCR detection of Yersinia pestis specific DNA from dental pulp of Black Death victims (Signoli, M.; Chev\u00e9, D.; Adalian, P.; Bo\u00ebtsch, G.; Dutour, O., eds.), La peste : entre \u00e9pid\u00e9mies et soci\u00e9t\u00e9s, Firenze University Press, Florence, Italie, 2007, pp. 265-269","journal-title":"Attempted PCR detection of <span class=\"italique\">Yersinia pestis<\/span> specific DNA from dental pulp of Black Death victims"},{"key":"key2025102316284122093_25","first-page":"23","article-title":"Palaeomicrobiology: current issues and perspectives","volume":"3","author":"Drancourt, M.","year":"2005","unstructured":"[25] Drancourt, M.; Raoult, D. 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