{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T02:21:37Z","timestamp":1792981297965,"version":"4.5.0"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T00:00:00Z","timestamp":1639180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Women's Health"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.crwh.2021.e00376","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T12:29:48Z","timestamp":1639484988000},"page":"e00376","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Multidose methotrexate treatment of cornual pregnancy after in vitro fertilization: Two case reports"],"prefix":"10.1016","volume":"33","author":[{"given":"T.","family":"Loukopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Zikopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Mastora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Galani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Stavros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Kolibianakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.crwh.2021.e00376_bb0005","series-title":"Jeffcoate\u2019s Principles of Gynaecology","author":"Malhorta","year":"2019"},{"issue":"2","key":"10.1016\/j.crwh.2021.e00376_bb0010","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4103\/0974-1208.44116","article-title":"Interstitial ectopic pregnancy: a rare and difficult clinicosonographic diagnosis","volume":"1","author":"Rastogi","year":"2008","journal-title":"J. Hum. Reprod. Sci."},{"key":"10.1016\/j.crwh.2021.e00376_bb0015","first-page":"5","article-title":"A case of a ruptured cornual in vitro fertilization pregnancy","volume":"5","author":"Ulu","year":"2016","journal-title":"J. Women\u2019s Health Care"},{"key":"10.1016\/j.crwh.2021.e00376_bb0020","first-page":"81","article-title":"Embarazo cornual","volume":"66","author":"Bonfante Ram\u00edrez","year":"1998","journal-title":"Ginecol. Obstet. Mex."},{"issue":"29","key":"10.1016\/j.crwh.2021.e00376_bb0025","article-title":"Successful conservative medical management of an interstitial ectopic pregnancy at 10 weeks of gestation: a case report","volume":"26","author":"Galani","year":"2020","journal-title":"Case Rep Womens Health."},{"issue":"6","key":"10.1016\/j.crwh.2021.e00376_bb0030","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1148\/rg.286085506","article-title":"Diagnostic clues to ectopic pregnancy","volume":"28","author":"Lin","year":"2008","journal-title":"Radiographics."},{"key":"10.1016\/j.crwh.2021.e00376_bb0035","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3109\/01443615.2013.819844","article-title":"Recurrent cornual pregnancy, successfully treated with methotrexate, following a ruptured pregnancy in the contralateral cornu","volume":"34","author":"Fabre-Gray","year":"2014","journal-title":"J. Obstet. Gynaecol."},{"issue":"3","key":"10.1016\/j.crwh.2021.e00376_bb0040","doi-asserted-by":"crossref","first-page":"203","DOI":"10.4103\/2229-516X.165364","article-title":"A true cornual pregnancy with placenta percreta resulting in a viable fetus","volume":"5","author":"Rathod","year":"2015","journal-title":"Int. J. Appl. Basic Med. Res."},{"key":"10.1016\/j.crwh.2021.e00376_bb0045","doi-asserted-by":"crossref","first-page":"4356036","DOI":"10.1155\/2017\/4356036","article-title":"Bilateral tubal pregnancy without known risk factor","volume":"2017","author":"Zaman\u00e9","year":"2017","journal-title":"Case Rep. Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.crwh.2021.e00376_bb0050","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jmig.2005.11.005","article-title":"Cornual gestation: a systematic literature review and two case reports of a novel treatment regimen","volume":"13","author":"Ross","year":"2006","journal-title":"J. Minim. Invasive Gynecol."},{"issue":"8","key":"10.1016\/j.crwh.2021.e00376_bb0055","article-title":"Methotrexate for cornual ectopic pregnancy","volume":"12","author":"Parker","year":"2020","journal-title":"Cureus"},{"key":"10.1016\/j.crwh.2021.e00376_bb0060","first-page":"Doc16","article-title":"Diagnosis and laparoscopic treatment of cornual ectopic pregnancy","volume":"8","author":"Walid","year":"2010","journal-title":"Ger. Med. Sci."},{"issue":"3","key":"10.1016\/j.crwh.2021.e00376_bb0065","doi-asserted-by":"crossref","first-page":"203","DOI":"10.4103\/2229-516X.165364","article-title":"A true cornual pregnancy with placenta percreta resulting in a viable fetus","volume":"5","author":"Rathod","year":"2015","journal-title":"Int. J. Appl. Basic Med. Res."},{"issue":"1","key":"10.1016\/j.crwh.2021.e00376_bb0070","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1159\/000491083","article-title":"Multidose methotrexate treatment of ectopic pregnancies with high initial \u03b2-human chorionic gonadotropin: can success be predicted?","volume":"84","author":"Tug","year":"2019","journal-title":"Gynecol. Obstet. Investig."},{"issue":"2","key":"10.1016\/j.crwh.2021.e00376_bb0075","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/GRF.0b013e3182510a73","article-title":"Medical management of ectopic pregnancy: a comparison of regimens","volume":"55","author":"Bachman","year":"2012","journal-title":"Clin. Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.crwh.2021.e00376_bb0080","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/s00404-009-0983-6","article-title":"Successful management of live ectopic pregnancy with high beta-hCG titres by ultrasound-guided potassium chloride injection and systemic methotrexate","volume":"280","author":"Dadhwal","year":"2009","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.crwh.2021.e00376_bb0085","first-page":"90","article-title":"Myometrial cystic formation after local methotrexate application into cornual gestational sac: a case report of an unexpected complication","volume":"61","author":"Ozkan","year":"2011","journal-title":"Case Rep. Obstet. Gynecol."}],"container-title":["Case Reports in Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214911221000941?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214911221000941?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T05:28:05Z","timestamp":1762406885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214911221000941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":17,"alternative-id":["S2214911221000941"],"URL":"https:\/\/doi.org\/10.1016\/j.crwh.2021.e00376","relation":{},"ISSN":["2214-9112"],"issn-type":[{"value":"2214-9112","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multidose methotrexate treatment of cornual pregnancy after in vitro fertilization: Two case reports","name":"articletitle","label":"Article Title"},{"value":"Case Reports in Women's Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.crwh.2021.e00376","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"e00376"}}