{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:24:25Z","timestamp":1786987465220,"version":"build-2736575974"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cryobiology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.cryobiol.2024.104980","type":"journal-article","created":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T12:51:17Z","timestamp":1730119877000},"page":"104980","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Taxifolin: A flavonoid in the freezing medium augments post-thaw semen quality and in vivo fertility potential of buffalo bull spermatozoa"],"prefix":"10.1016","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3180-8208","authenticated-orcid":false,"given":"Hussain","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Umar","family":"Ijaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehreen","family":"Riaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhad","family":"Ullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haney","family":"Samir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Shuaib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman A.","family":"Swelum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cryobiol.2024.104980_bib8","doi-asserted-by":"crossref","DOI":"10.1111\/rda.14515","article-title":"Coenzyme Q10 improves the quality and in vitro fertility of post\u2010thawed buffalo (Bubalus bubalis) semen via its antioxidative effect","volume":"59","author":"Ahmed","year":"2024","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.cryobiol.2024.104980_bib42","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0378-4320(00)00152-4","article-title":"Basic aspects of frozen storage of semen","volume":"62","author":"Holt","year":"2000","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib43","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0093-691X(99)00239-3","article-title":"Fundamental aspects of sperm cryobiology: the importance of species and individual differences","volume":"53","author":"Holt","year":"2000","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib36","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/S1472-6483(10)61780-4","article-title":"Fundamentals of cryobiology in reproductive medicine","volume":"9","author":"Fuller","year":"2004","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.cryobiol.2024.104980_bib44","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1530\/jrf.0.0470255","article-title":"The lipids of buffalo spermatozoa and seminal plasma","volume":"47","author":"Jain","year":"1976","journal-title":"Reproduction"},{"key":"10.1016\/j.cryobiol.2024.104980_bib3","first-page":"173","article-title":"Effect of cryopreservation on CASA characteristics, mitochondrial transmembrane potential, plasma and acrosome integrities, morphology and in vivo fertility of buffalo bull spermatozoa","volume":"40","author":"Ahmed","year":"2019","journal-title":"Cryo-Letters"},{"key":"10.1016\/j.cryobiol.2024.104980_bib9","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1095\/biolreprod41.1.183","article-title":"Generation of reactive oxygen species, lipid peroxidation, and human sperm function","volume":"41","author":"Aitken","year":"1989","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.cryobiol.2024.104980_bib67","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1111\/and.12236","article-title":"Antioxidative effects of cysteamine, hyaluronan and fetuin on post\u2010thaw semen quality, DNA integrity and oxidative stress parameters in the Brown Swiss bull","volume":"47","author":"Sar\u0131\u00f6zkan","year":"2015","journal-title":"Andrologia"},{"key":"10.1016\/j.cryobiol.2024.104980_bib10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4103\/1008-682X.122203","article-title":"Oxidative stress and male reproductive health","volume":"16","author":"Aitken","year":"2014","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.cryobiol.2024.104980_bib15","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.cryobiol.2019.10.200","article-title":"Effect of the addition of different catalase concentrations to a TRIS-egg yolk extender on quality and in vitro fertilization rate of frozen-thawed bull sperm","volume":"91","author":"Arslan","year":"2019","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib49","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.anireprosci.2014.11.015","article-title":"Sericin supplementation improves semen freezability of buffalo bulls by minimizing oxidative stress during cryopreservation","volume":"152","author":"Kumar","year":"2015","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib55","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1111\/j.1439-0531.2012.01990.x","article-title":"Effect of several antioxidants on thawed ram spermatozoa submitted to 37 C up to four hours","volume":"47","author":"Mata\u2010Campuzano","year":"2012","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.cryobiol.2024.104980_bib21","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1002\/mrd.10347","article-title":"Roles of antioxidants on prolonged storage of avian spermatozoa in vivo and in vitro","volume":"66","author":"Br\u00e9que","year":"2003","journal-title":"Mol. Reprod. Dev.: Incorporating Gamete Research"},{"key":"10.1016\/j.cryobiol.2024.104980_bib14","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cryobiol.2019.03.008","article-title":"Effects of supplementation of Tris-egg yolk extender with royal jelly on chilled and frozen-thawed ram semen characteristics","volume":"88","author":"Amini","year":"2019","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib26","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.theriogenology.2006.02.022","article-title":"Effect of docosahexaenoic acid and \u03b1-tocopherol enrichment in chicken sperm on semen quality, sperm lipid composition and susceptibility to peroxidation","volume":"66","author":"Cerolini","year":"2006","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12864-020-07280-9","article-title":"The micro-RNA content of unsorted cryopreserved bovine sperm and its relation to the fertility of sperm after sex-sorting","volume":"22","author":"Keles","year":"2021","journal-title":"BMC Genom."},{"key":"10.1016\/j.cryobiol.2024.104980_bib60","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.theriogenology.2011.11.006","article-title":"Effect of cryopreservation on sperm parameters, lipid peroxidation and antioxidant enzymes activity in fowl semen","volume":"77","author":"Partyka","year":"2012","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib58","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.anireprosci.2005.11.002","article-title":"A comparative study on lipid peroxidation, activities of antioxidant enzymes and viability of cattle and buffalo bull spermatozoa during storage at refrigeration temperature","volume":"96","author":"Nair","year":"2006","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2020.604460","article-title":"Effect of quercetin supplementation in extender on sperm kinematics, extracellular enzymes release, and oxidative stress of Egyptian buffalo bulls frozen\u2013thawed semen","volume":"7","author":"El-Khawagah","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib34","first-page":"659","article-title":"Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition","volume":"2","author":"Ferry","year":"1996","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.cryobiol.2024.104980_bib62","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1124\/jpet.302.1.66","article-title":"Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries","volume":"302","author":"Perez-Vizca\u0131no","year":"2002","journal-title":"J. Pharmacol. Exp. Therapeut."},{"issue":"22","key":"10.1016\/j.cryobiol.2024.104980_bib51","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s11658-017-0066-9","article-title":"The mechanism of (\u00fe) taxifolin's protective antioxidant effect for OH-treated bone marrow-derived mesenchymal stem cells","volume":"27","author":"Li","year":"2017","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.cryobiol.2024.104980_bib65","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1186\/s12885-018-4959-4","article-title":"Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt\/b -catenin signaling pathway","volume":"26","author":"Razak","year":"2018","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cryobiol.2024.104980_bib73","article-title":"Taxifolin enhances and rographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cryobiol.2024.104980_bib53","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.biochi.2015.10.014","article-title":"Taxifolin curbs NF-kB-mediated Wnt\/b-catenin signaling via up-regulating Nrf2 pathway in experimental colon carcinogenesis","volume":"119","author":"Manigandan","year":"2015","journal-title":"Biochimie"},{"issue":"3","key":"10.1016\/j.cryobiol.2024.104980_bib11","doi-asserted-by":"crossref","DOI":"10.1515\/jbcpp-2018-0230","article-title":"Ameliorative effect of quercetin, catechin, and taxifolin on rotenone-induced testicular and splenic weight gain and oxidative stress in rats","volume":"31","author":"Akinmoladun","year":"2020","journal-title":"J. Basic Clin. Physiol. Pharmacol."},{"key":"10.1016\/j.cryobiol.2024.104980_bib40","doi-asserted-by":"crossref","first-page":"S110","DOI":"10.4103\/pm.pm_601_17","article-title":"Taxifolin possesses anti-cancer activity on the 7, 12-Dimethylbenz (a) anthracene-Induced breast cancer in the sprague dawley rats by remodeling nuclear factor Erythroid 2-Kelch-Like ECH-Associated Protein 1-Heme Oxygenase 1 and anti-oxidant pathways","volume":"14","author":"Haque","year":"2018","journal-title":"Phcog. Mag."},{"key":"10.1016\/j.cryobiol.2024.104980_bib75","first-page":"2019","article-title":"Antigenotoxic effects of biochaga and dihydroquercetin (taxifolin) on H2O2-induced DNA damage in human whole blood cells","volume":"11","author":"\u017divkovi\u0107","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.cryobiol.2024.104980_bib33","doi-asserted-by":"crossref","first-page":"595","DOI":"10.3891\/acta.chem.scand.12-0595","article-title":"Soluble diaphorase in animal tissues","volume":"12","author":"Ernster","year":"1958","journal-title":"Acta Chem. Scand."},{"key":"10.1016\/j.cryobiol.2024.104980_bib76","first-page":"235","article-title":"The effect of different concentrations of taxifolin on the quality of frozen and thawed semen of Simmental cattle","volume":"24","author":"Zolfaghari","year":"2023","journal-title":"Iran. J. Vet. Res."},{"key":"10.1016\/j.cryobiol.2024.104980_bib25","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.theriogenology.2023.05.004","article-title":"Use of the flavonoid taxifolin for sperm cryopreservation from the threatened Bermeya goat breed","volume":"206","author":"Caama\u00f1o","year":"2023","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib1","series-title":"Investigations on Fertility Related Biomarkers in Buffalo Semen to Reduce Male Factor Losses (MFLs)","author":"Ahmed","year":"2016"},{"key":"10.1016\/j.cryobiol.2024.104980_bib2","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.theriogenology.2016.05.010","article-title":"Semen quality parameters as fertility predictors of water buffalo bull spermatozoa during low breeding season","volume":"86","author":"Ahmed","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib68","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1021\/jf00018a005","article-title":"T, Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion","volume":"40","author":"Shimada","year":"1992","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.cryobiol.2024.104980_bib29","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1515\/CCLM.2008.062","article-title":"Simple method for determining human serum 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) radical scavenging activity\u2013possible application in clinical studies on dietary antioxidants","volume":"46","author":"Chrzczanowicz","year":"2008","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.cryobiol.2024.104980_bib37","series-title":"The Quantitative Analysis of Drugs","first-page":"456","author":"Garrat","year":"1964"},{"key":"10.1016\/j.cryobiol.2024.104980_bib22","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/S0093-691X(03)00174-2","article-title":"Comparison of methods to evaluate the plasmalemma of bovine sperm and their relationship with in vitro fertilization rate","volume":"60","author":"Brito","year":"2003","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib27","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1093\/oxfordjournals.humrep.a137495","article-title":"Combined supravital staining and hypoosmotic swelling","volume":"6","author":"Chan","year":"1991","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.cryobiol.2024.104980_bib6","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.cryobiol.2022.05.004","article-title":"The ameliorating effects of crocetin on frozen-thawed quality, and fertility via attenuating oxidative status of bubaline spermatozoa","volume":"107","author":"Ahmed","year":"2022","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib56","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1530\/jrf.0.0950755","article-title":"Distinction between true acrosome reaction and degenerative acrosome loss by a one-step staining method using Pisum sativum agglutinin","volume":"95","author":"Mendoza","year":"1992","journal-title":"Reproduction"},{"key":"10.1016\/j.cryobiol.2024.104980_bib54","first-page":"94","article-title":"The use of the acridine orange test and the TUNEL assay to assess the integrity of freeze-dried bovine spermatozoa DNA","volume":"6","author":"Martins","year":"2007","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.cryobiol.2024.104980_bib19","series-title":"Red Cell Metabolism. A Manual of Biochemical Methods","first-page":"71","article-title":"Catalase","author":"Beutler","year":"1975"},{"key":"10.1016\/j.cryobiol.2024.104980_bib20","series-title":"Glutathione in Red Blood Cell Metabolism. A Manual of Biochemical Methods","first-page":"112","author":"Beutler","year":"1975"},{"key":"10.1016\/j.cryobiol.2024.104980_bib35","first-page":"92","article-title":"Formation or removal of oxygen radicals","volume":"105","author":"Floh\u00e9","year":"1984","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.cryobiol.2024.104980_bib18","first-page":"882","article-title":"Improved method for the determination of blood glutathione","volume":"61","author":"Beutler","year":"1963","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.cryobiol.2024.104980_bib48","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.theriogenology.2013.11.012","article-title":"Glutathione-S-transferase: role in buffalo (Bubalus bubalis) sperm capacitation and cryopreservation","volume":"81","author":"Kumar","year":"2014","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib74","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1002\/elps.200800033","article-title":"Intracellular adenosine 5\u2032\u2010triphosphate, adenosine 5\u2032\u2010diphosphate, and adenosine 5\u2032\u2010monophosphate detection by short\u2010end injection capillary electrophoresis using methylcellulose as the effective electroosmostic flow suppressor","volume":"29","author":"Zinellu","year":"2008","journal-title":"Electrophoresis"},{"key":"10.1016\/j.cryobiol.2024.104980_bib17","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: the FRAP assay","volume":"239","author":"Benzie","year":"1996","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.cryobiol.2024.104980_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.anireprosci.2021.106761","article-title":"Improving the quality and in vitro fertilization rate of frozen-thawed semen of buffalo (Bubalus bubalis) bulls with the inclusion of vitamin B12 in the cryopreservation medium","volume":"229","author":"Ahmed","year":"2021","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib64","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.cryobiol.2023.04.003","article-title":"Reducing oxidative stress by \u03ba-carrageenan and C60HyFn: the post-thaw quality and antioxidant status of Azari water buffalo bull semen","volume":"111","author":"Ramazani","year":"2023","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib7","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.rvsc.2023.03.020","article-title":"Sulforaphane inclusion in a freezing medium augments post-thaw motility, functional and biochemical features, and fertility potential of buffalo (Bubalus bubalis) spermatozoa","volume":"158","author":"Ahmed","year":"2023","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib70","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cryobiol.2020.06.010","article-title":"Caffeic acid improves microscopic sperm parameters and antioxidant status of buffalo (Bubalus bubalis) bull semen following freeze-thawing process","volume":"95","author":"Soleimanzadeh","year":"2020","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib24","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.cryobiol.2020.09.001","article-title":"Decreasing glycerol content by co-supplementation of trehalose and taxifolin hydrate in ram semen extender: microscopic, oxidative stress, and gene expression analyses","volume":"96","author":"Bucak","year":"2020","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib13","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/mrd.1080420311","article-title":"Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa","volume":"42","author":"Alvarez","year":"1995","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.cryobiol.2024.104980_bib23","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.cryobiol.2010.09.001","article-title":"S, Effects of antioxidants on post-thawed bovine sperm and oxidative stress parameters: antioxidants protect DNA integrity against cryodamage","volume":"61","author":"Bucak","year":"2010","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib45","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/BF01919321","article-title":"J Lauterwein, Spermatozoa: models for studying regulatory aspects of","volume":"52","author":"Kamp","year":"1996","journal-title":"energy metabolism Experientia"},{"key":"10.1016\/j.cryobiol.2024.104980_bib57","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/j.1939-4640.1999.tb02517.x","article-title":"Rabbit spermatozoa: a model system for studying ATP homeostasis and motility","volume":"20","author":"Minelli","year":"1999","journal-title":"J. Androl."},{"key":"10.1016\/j.cryobiol.2024.104980_bib63","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0093-691X(03)00248-6","article-title":"Regression analyses and motile sperm subpopulation structure study as improving tools in boar semen quality analysis","volume":"61","author":"Quintero-Moreno","year":"2004","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib38","doi-asserted-by":"crossref","first-page":"449","DOI":"10.2164\/jandrol.107.003533","article-title":"Adenosine triphosphate production by bovine spermatozoa and its relationship to semen fertilizing ability","volume":"29","author":"Garrett","year":"2008","journal-title":"J. Androl."},{"key":"10.1016\/j.cryobiol.2024.104980_bib41","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1006\/dbio.2002.0797","article-title":"Hyperactivated motility of bull sperm is triggered at the axoneme by Ca2+ and not Camp","volume":"250","author":"Ho","year":"2021","journal-title":"Dev. Biol."},{"key":"10.1016\/j.cryobiol.2024.104980_bib69","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1002\/j.1939-4640.1995.tb00566.x","article-title":"Role of oxidative stress and antioxidants in male infertility","volume":"16","author":"Sikka","year":"1995","journal-title":"J. Androl."},{"key":"10.1016\/j.cryobiol.2024.104980_bib4","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.theriogenology.2020.04.034","article-title":"The addition of resveratrol in tris citric acid extender ameliorates post-thaw quality parameters, antioxidant enzymes levels, and fertilizing capability of buffalo (Bubalus bubalis) bull spermatozoa","volume":"152","author":"Ahmed","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib52","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1007\/s13224-011-0070-3","article-title":"Association of oxidative stress biomarkers and antioxidant enzymatic activity in male infertility of north-East India","volume":"62","author":"Mahanta","year":"2012","journal-title":"J. Obstet. Gynaecol. India"},{"key":"10.1016\/j.cryobiol.2024.104980_bib71","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1111\/and.12148","article-title":"Effect of cysteine and glutamine added to extender on post\u2010thaw sperm functional parameters of buffalo bull","volume":"46","author":"Topraggaleh","year":"2014","journal-title":"Andrologia"},{"key":"10.1016\/j.cryobiol.2024.104980_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231810574","article-title":"Reactive nitrogen species and male reproduction: physiological and pathological aspects","volume":"23","author":"Dutta","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib66","first-page":"231","article-title":"Etiologies of sperm oxidative stress","volume":"14","author":"Sabeti","year":"2016","journal-title":"International Journal of Reproductive Biomedicine"},{"issue":"39","key":"10.1016\/j.cryobiol.2024.104980_bib12","doi-asserted-by":"crossref","first-page":"346","DOI":"10.5534\/wjmh.190145","article-title":"Coenzyme Q10 improves sperm parameters, oxidative stress markers and sperm DNA fragmentation in infertile patients with idiopathic oligoasthenozoospermia","volume":"39","author":"Alahmar","year":"2021","journal-title":"The world journal of men's health"},{"key":"10.1016\/j.cryobiol.2024.104980_bib30","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1016\/j.bbagen.2014.10.020","article-title":"ROS, thiols and thiol regulating systems in male gametogenesis","volume":"1850","author":"Conrad","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cryobiol.2024.104980_bib28","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.3390\/ijms24021680","article-title":"The involvement of natural polyphenols in molecular mechanisms inducing apoptosis in tumor cells: a promising adjuvant in cancer therapy","volume":"24","author":"Chimento","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.cryobiol.2024.104980_bib39","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.theriogenology.2012.06.032","article-title":"Quercetin improves the post-thaw characteristics of cryopreserved sex-sorted and non-sorted stallion sperm","volume":"79","author":"Gibb","year":"2013","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib46","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.cryobiol.2020.08.006","article-title":"Effect of quercetin on the motility of cryopreserved canine spermatozoa","volume":"96","author":"Kawasaki","year":"2020","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib59","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.theriogenology.2020.04.033","article-title":"Effect of quercetin loaded liposomes or nanostructured lipid carrier (NLC) on postthawed sperm quality and fertility of rooster sperm","volume":"152","author":"Najafi","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib61","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1093\/carcin\/17.6.1305","article-title":"Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane- induced colon cancer and 7, 12- dimethylbenz(a)anthracene-induced mammary cancer in rats","volume":"17","author":"Pereira","year":"1996","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.cryobiol.2024.104980_bib72","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.repbio.2020.06.002","article-title":"Quercetin supplementation to the thawing and incubation media of boar sperm improves post-thaw sperm characteristics and the in vitro production of pig embryos","volume":"20","author":"Winn","year":"2020","journal-title":"Reprod. Biol."},{"key":"10.1016\/j.cryobiol.2024.104980_bib77","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.cryobiol.2012.09.003","article-title":"Effect of freezing-thawing process and quercetin on human sperm survival and DNA integrity","volume":"65","author":"Zribi","year":"2012","journal-title":"Cryobiology"},{"key":"10.1016\/j.cryobiol.2024.104980_bib50","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.rbmo.2009.09.014","article-title":"Oxidative stress and medical antioxidant treatment in male infertility","volume":"19","author":"Lanzafame","year":"2009","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.cryobiol.2024.104980_bib16","first-page":"246","article-title":"The effect of antioxidant supplementation in semen extenders on semen quality and lipid peroxidation of chilled bull spermatozoa","volume":"13","author":"Asadpour","year":"2012","journal-title":"Iran. J. Vet. Res."}],"container-title":["Cryobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011224024001354?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011224024001354?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T06:52:41Z","timestamp":1739429561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0011224024001354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":77,"alternative-id":["S0011224024001354"],"URL":"https:\/\/doi.org\/10.1016\/j.cryobiol.2024.104980","relation":{},"ISSN":["0011-2240"],"issn-type":[{"value":"0011-2240","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Taxifolin: A flavonoid in the freezing medium augments post-thaw semen quality and in vivo fertility potential of buffalo bull spermatozoa","name":"articletitle","label":"Article Title"},{"value":"Cryobiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cryobiol.2024.104980","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc. on behalf of Society for Cryobiology.","name":"copyright","label":"Copyright"}],"article-number":"104980"}}