{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T22:10:49Z","timestamp":1778019049267,"version":"3.51.4"},"reference-count":78,"publisher":"American Association for the Advancement of Science (AAAS)","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T00:00:00Z","timestamp":1695427200000},"content-version":"vor","delay-in-days":265,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31900422"],"award-info":[{"award-number":["31900422"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270584"],"award-info":[{"award-number":["32270584"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023M732990"],"award-info":[{"award-number":["2023M732990"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010023","name":"Natural Science Research of Jiangsu Higher Education Institutions of China","doi-asserted-by":"publisher","award":["23KJB180028"],"award-info":[{"award-number":["23KJB180028"]}],"id":[{"id":"10.13039\/501100010023","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013280","name":"Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013280","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","award":["D18007"],"award-info":[{"award-number":["D18007"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["csbj.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Comput Struct Biotechnol J"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.csbj.2023.09.029","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T17:41:24Z","timestamp":1695663684000},"page":"4580-4588","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Regulation of the three-dimensional chromatin organization by transposable elements in pig spleen"],"prefix":"10.34133","volume":"21","author":[{"given":"Yuzhuo","family":"Li","sequence":"first","affiliation":[{"name":"Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hairui","family":"Fan","sequence":"additional","affiliation":[{"name":"Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu, China"},{"name":"College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiyun","family":"Qin","sequence":"additional","affiliation":[{"name":"Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu, China"},{"name":"College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yejun","family":"Wang","sequence":"additional","affiliation":[{"name":"Youth Innovation Team of Medical Bioinformatics, Shenzhen University Health Science Center, Shenzhen 518060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbin","family":"Bao","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-an","family":"Sun","sequence":"additional","affiliation":[{"name":"Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu, China"},{"name":"Joint International Research Laboratory of Important Animal Infectious Diseases and Zoonoses of Jiangsu Higher Education Institutions, Yangzhou University, Yangzhou 225009, China"},{"name":"Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou 225009, Jiangsu, China"},{"name":"Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou 225009, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"221","published-online":{"date-parts":[[2023,9,27]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg.2016.112"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-019-0128-0"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaw1668"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1181369"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.11.021"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2016.138"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-019-0132-4"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3663"},{"key":"e_1_3_5_10_2","doi-asserted-by":"crossref","DOI":"10.1038\/s41586-023-05961-5","article-title":"CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion","author":"Davidson I.F.","year":"2023","unstructured":"Davidson I.F., Barth R., Zaczek M., van der Torre J., Tang W., Nagasaka K., Janissen R., Kerssemakers J., Wutz G., Dekker C. et al: CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion. Nature 2023; .","journal-title":"Nature"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.11.024"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.12.048"},{"key":"e_1_3_5_13_2","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1182\/blood.2020005780","article-title":"Dynamic CTCF binding directly mediates interactions among cis-regulatory elements essential for hematopoiesis","volume":"137","author":"Qi Q.","year":"2021","unstructured":"Qi Q., Cheng L., Tang X., He Y., Li Y., Yee T., Shrestha D., Feng R., Xu P., Zhou X. et al: Dynamic CTCF binding directly mediates interactions among cis-regulatory elements essential for hematopoiesis. Blood 2021; 137: 1327.","journal-title":"Blood"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks158"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-021-01008-5"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-020-0643-0"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4370"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.02.029"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2015.09.004"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genet-040620-022145"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.277150.122"},{"key":"e_1_3_5_22_2","doi-asserted-by":"crossref","DOI":"10.1038\/s41594-023-00960-6","article-title":"Regulation of human trophoblast gene expression by endogenous retroviruses","author":"Frost J.M.","year":"2023","unstructured":"Frost J.M., Amante S.M., Okae H., Jones E.M., Ashley B., Lewis R.M., Cleal J.K., Caley M.P., Arima T., Maffucci T. et al: Regulation of human trophoblast gene expression by endogenous retroviruses. Nat Struct Mol Biol 2023; .","journal-title":"Nat Struct Mol Biol"},{"key":"e_1_3_5_23_2","article-title":"Ruminant-specific retrotransposons shape regulatory evolution of bovine immunity","author":"Kelly C.J.","year":"2022","unstructured":"Kelly C.J., Chitko-McKown C.G. and Chuong E.B.: Ruminant-specific retrotransposons shape regulatory evolution of bovine immunity. Genome Res 2022; .","journal-title":"Genome Res"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-021-00385-1"},{"key":"e_1_3_5_25_2","doi-asserted-by":"crossref","DOI":"10.1038\/s41576-023-00609-6","article-title":"Transposable elements in mammalian chromatin organization","author":"Lawson H.A.","year":"2023","unstructured":"Lawson H.A., Liang Y. and Wang T.: Transposable elements in mammalian chromatin organization. Nat Rev Genet 2023; .","journal-title":"Nat Rev Genet"},{"key":"e_1_3_5_26_2","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/s12915-020-00863-8","article-title":"Functional signatures of evolutionarily young CTCF binding sites","volume":"18","author":"Azazi D.","year":"2020","unstructured":"Azazi D., Mudge J.M., Odom D.T. and Flicek P.: Functional signatures of evolutionarily young CTCF binding sites. BMC Biol 2020; 18: 132.","journal-title":"BMC Biol"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.080663.108"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.600"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.168872.113"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.11.058"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-019-1916-8"},{"key":"e_1_3_5_32_2","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/s41467-023-36364-9","article-title":"Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes","volume":"14","author":"Choudhary M.N.K.","year":"2023","unstructured":"Choudhary M.N.K., Quaid K., Xing X., Schmidt H. and Wang T.: Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes. Nat Commun 2023; 14: 634.","journal-title":"Nat Commun"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15520-5"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abd5758"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature11622"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-020-04925-8"},{"key":"e_1_3_5_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-020-00613-9"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2553"},{"key":"e_1_3_5_39_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-020-02164-3"},{"key":"e_1_3_5_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msab223"},{"key":"e_1_3_5_41_2","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-23560-8","article-title":"A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription","volume":"12","author":"Jin L.","year":"2021","unstructured":"Jin L., Tang Q., Hu S., Chen Z., Zhou X., Zeng B., Wang Y., He M., Li Y., Gui L. et al: A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription. Nat Commun 2021; 12: 3715.","journal-title":"Nat Commun"},{"key":"e_1_3_5_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-22100-8"},{"key":"e_1_3_5_43_2","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12915-022-01301-7","article-title":"Comparative 3D genome architecture in vertebrates","volume":"20","author":"Li D.","year":"2022","unstructured":"Li D., He M., Tang Q., Tian S., Zhang J., Li Y., Wang D., Jin L., Ning C., Zhu W. et al: Comparative 3D genome architecture in vertebrates. BMC Biol 2022; 20: 99.","journal-title":"BMC Biol"},{"key":"e_1_3_5_44_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-26153-7"},{"key":"e_1_3_5_45_2","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1038\/s41467-021-22448-x","article-title":"A compendium and comparative epigenomics analysis of cis-regulatory elements in the pig genome","volume":"12","author":"Zhao Y.","year":"2021","unstructured":"Zhao Y., Hou Y., Xu Y., Luan Y., Zhou H., Qi X., Hu M., Wang D., Wang Z., Fu Y. et al: A compendium and comparative epigenomics analysis of cis-regulatory elements in the pig genome. Nat Commun 2021; 12: 2217.","journal-title":"Nat Commun"},{"key":"e_1_3_5_46_2","first-page":"D682","article-title":"Ensembl 2020","volume":"48","author":"Yates A.D.","year":"2020","unstructured":"Yates A.D., Achuthan P., Akanni W., Allen J., Allen J., Alvarez-Jarreta J., Amode M.R., Armean I.M., Azov A.G., Bennett R. et al: Ensembl 2020. Nucleic Acids Res 2020; 48: D682.","journal-title":"Nucleic Acids Res"},{"key":"e_1_3_5_47_2","first-page":"D756","article-title":"UCSC genome browser enters 20th year","volume":"48","author":"Lee C.M.","year":"2020","unstructured":"Lee C.M., Barber G.P., Casper J., Clawson H., Diekhans M., Gonzalez J.N., Hinrichs A.S., Lee B.T., Nassar L.R., Powell C.C. et al: UCSC genome browser enters 20th year. Nucleic Acids Res 2020; 48: D756.","journal-title":"Nucleic Acids Res"},{"key":"e_1_3_5_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1923"},{"key":"e_1_3_5_49_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2008-9-9-r137"},{"key":"e_1_3_5_50_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku365"},{"key":"e_1_3_5_51_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts635"},{"key":"e_1_3_5_52_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp352"},{"key":"e_1_3_5_53_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp324"},{"key":"e_1_3_5_54_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-015-0831-x"},{"key":"e_1_3_5_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.05.004"},{"key":"e_1_3_5_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2016.07.002"},{"key":"e_1_3_5_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2148"},{"key":"e_1_3_5_58_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq033"},{"key":"e_1_3_5_59_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv145"},{"key":"e_1_3_5_60_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09234-6"},{"key":"e_1_3_5_61_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr189"},{"key":"e_1_3_5_62_2","unstructured":"Team R.C. (2020). R: A language and environment for statistical computing. R Foundation for Statistical Computing Vienna Austria."},{"key":"e_1_3_5_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2015.07.012"},{"key":"e_1_3_5_64_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature11247"},{"key":"e_1_3_5_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13992"},{"key":"e_1_3_5_66_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041374"},{"key":"e_1_3_5_67_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.917"},{"key":"e_1_3_5_68_2","doi-asserted-by":"crossref","first-page":"R148","DOI":"10.1186\/gb-2013-14-12-r148","article-title":"Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes","volume":"14","author":"Schwalie P.C.","year":"2013","unstructured":"Schwalie P.C., Ward M.C., Cain C.E., Faure A.J., Gilad Y., Odom D.T. and Flicek P.: Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes. Genome Biol 2013; 14: R148.","journal-title":"Genome Biol"},{"key":"e_1_3_5_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.10.010"},{"key":"e_1_3_5_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10716"},{"key":"e_1_3_5_71_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-019-1894-x"},{"key":"e_1_3_5_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2011.10.003"},{"key":"e_1_3_5_73_2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13100-021-00248-w","article-title":"A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1","volume":"12","author":"Wang X.","year":"2021","unstructured":"Wang X., Chen Z., Murani E., D'Alessandro E., An Y., Chen C., Li K., Galeano G., Wimmers K. and Song C.: A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1. Mob DNA 2021; 12: 20.","journal-title":"Mob DNA"},{"key":"e_1_3_5_74_2","article-title":"Inhibition of EZH2 causes retrotransposon derepression and immune activation in porcine lung alveolar macrophages","volume":"24","author":"Zhang L.","year":"2023","unstructured":"Zhang L., Jin J., Qin W., Jiang J., Bao W. and Sun M.A.: Inhibition of EZH2 causes retrotransposon derepression and immune activation in porcine lung alveolar macrophages. Int J Mol Sci 2023; 24.","journal-title":"Int J Mol Sci"},{"key":"e_1_3_5_75_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aau6085"},{"key":"e_1_3_5_76_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-020-00539-5"},{"key":"e_1_3_5_77_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni0607-547"},{"key":"e_1_3_5_78_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad5497"},{"key":"e_1_3_5_79_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1912008117"}],"container-title":["Computational and Structural Biotechnology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2001037023003410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2001037023003410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/spj.science.org\/doi\/pdf\/10.1016\/j.csbj.2023.09.029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T21:12:52Z","timestamp":1778015572000},"score":1,"resource":{"primary":{"URL":"https:\/\/spj.science.org\/doi\/10.1016\/j.csbj.2023.09.029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":78,"alternative-id":["10.1016\/j.csbj.2023.09.029"],"URL":"https:\/\/doi.org\/10.1016\/j.csbj.2023.09.029","relation":{},"ISSN":["2001-0370"],"issn-type":[{"value":"2001-0370","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regulation of the three-dimensional chromatin organization by transposable elements in pig spleen","name":"articletitle","label":"Article Title"},{"value":"Computational and Structural Biotechnology Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.csbj.2023.09.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.","name":"copyright","label":"Copyright"}]}}