{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T07:12:20Z","timestamp":1788592340698,"version":"build-2803163510"},"reference-count":24,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K15437"],"award-info":[{"award-number":["23K15437"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K11808"],"award-info":[{"award-number":["24K11808"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Stress and Chaperones"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.cstres.2026.100209","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:35:08Z","timestamp":1787787308000},"page":"100209","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Urinary HSP90 as a non-invasive biomarker of active tubular injury in kidney transplant recipients: A multicenter prospective study"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8395-3824","authenticated-orcid":false,"given":"Kimihito","family":"Tachikawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Maehana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Shindo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2046-5051","authenticated-orcid":false,"given":"Yuki","family":"Kyoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayato","family":"Nishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1592-931X","authenticated-orcid":false,"given":"Hiroshi","family":"Kitamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Tsuji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Masumori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cstres.2026.100209_bib1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/ki.2009.377","article-title":"Kidney disease: improving global outcomes, KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary","volume":"77","author":"Kasiske","year":"2010","journal-title":"Kidney Int"},{"key":"10.1016\/j.cstres.2026.100209_bib2","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1056\/NEJMra2014530","article-title":"Long-term survival after kidney transplantation","volume":"385","author":"Hariharan","year":"2021","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cstres.2026.100209_bib3","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1111\/ajt.16463","article-title":"Long-term kidney transplant graft survival-Making progress when most needed","volume":"21","author":"Poggio","year":"2021","journal-title":"Am J Transpl"},{"key":"10.1016\/j.cstres.2026.100209_bib4","doi-asserted-by":"crossref","first-page":"6424","DOI":"10.3390\/jcm12196424","article-title":"Renal biopsy for diagnosis in kidney disease: indication, technique, and safety","volume":"12","author":"Schnuelle","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.cstres.2026.100209_bib5","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.3390\/ijms19092560","article-title":"The HSP90 family: structure, regulation, function, and implications in health and disease","volume":"19","author":"Hoter","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.cstres.2026.100209_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.cstres.2026.100190","article-title":"Hsp90: a means to an end","volume":"31","author":"Whalen","year":"2026","journal-title":"Cell Stress Chaperon"},{"key":"10.1016\/j.cstres.2026.100209_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0162942","article-title":"Heat shock protein 90\u03b1 is a potential serological biomarker of acute rejection after renal transplantation","volume":"11","author":"Maehana","year":"2016","journal-title":"PLOS One"},{"key":"10.1016\/j.cstres.2026.100209_bib8","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s12192-017-0790-0","article-title":"Heat shock proteins and kidney disease: perspectives of HSP therapy","volume":"22","author":"Chebotareva","year":"2017","journal-title":"Cell Stress Chaperon"},{"key":"10.1016\/j.cstres.2026.100209_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0109407","article-title":"Hsp72 is a novel biomarker to predict acute kidney injury in critically ill patients","volume":"9","author":"Morales-Buenrostro","year":"2014","journal-title":"PLOS One"},{"key":"10.1016\/j.cstres.2026.100209_bib10","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/nep.12240","article-title":"Tubular urinary biomarkers do not identify aetiology of acute kidney injury in kidney transplant recipients","volume":"19","author":"Ramirez-Sandoval","year":"2014","journal-title":"Nephrol (Carlton)"},{"key":"10.1016\/j.cstres.2026.100209_bib11","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1007\/s12192-015-0622-z","article-title":"Mediators and mechanisms of heat shock protein 70 based cytoprotection in obstructive nephropathy","volume":"20","author":"Mazzei","year":"2015","journal-title":"Cell Stress Chaperon"},{"key":"10.1016\/j.cstres.2026.100209_bib12","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1007\/s00467-016-3361-1","article-title":"Urine heat shock protein 70 levels as a marker of urinary tract infection in children","volume":"31","author":"Yilmaz","year":"2016","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.cstres.2026.100209_bib13","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/s00467-022-05664-5","article-title":"Urinary HSP70 improves diagnostic accuracy for urinary tract infection in children: UTILISE study","volume":"38","author":"Yilmaz","year":"2023","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.cstres.2026.100209_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fruro.2023.1281081","article-title":"The relationship between urine heat shock protein 70 and congenital anomalies of the kidney and urinary tract: UTILISE study","volume":"3","author":"Aksu","year":"2024","journal-title":"Front Urol"},{"key":"10.1016\/j.cstres.2026.100209_bib15","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1097\/01.TP.0000156165.83160.09","article-title":"Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations","volume":"79","author":"Hirsch","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.cstres.2026.100209_bib16","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2215\/CJN.04800908","article-title":"Calcineurin inhibitor nephrotoxicity","volume":"4","author":"Naesens","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.cstres.2026.100209_bib17","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/ajt.14625","article-title":"The Banff 2017 Kidney Meeting Report: revised diagnostic criteria for chronic active T cell-mediated rejection, antibody-mediated rejection, and prospects for integrative endpoints for next-generation clinical trials","volume":"18","author":"Haas","year":"2018","journal-title":"Am J Transpl"},{"key":"10.1016\/j.cstres.2026.100209_bib18","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/ajt.14609","article-title":"The causes, significance and consequences of inflammatory fibrosis in kidney transplantation: the Banff i-IFTA lesion","volume":"18","author":"Nankivell","year":"2018","journal-title":"Am J Transpl"},{"key":"10.1016\/j.cstres.2026.100209_bib19","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s12192-022-01272-2","article-title":"Heat shock protein 90 is a new potential target of anti-rejection therapy in allotransplantation","volume":"27","author":"Maehana","year":"2022","journal-title":"Cell Stress Chaperon"},{"key":"10.1016\/j.cstres.2026.100209_bib20","doi-asserted-by":"crossref","first-page":"405","DOI":"10.3109\/08860229509037605","article-title":"Induction of heat-shock proteins HSP73 and HSP90 in rat kidneys after ischemia","volume":"17","author":"Morita","year":"1995","journal-title":"Ren Fail"},{"key":"10.1016\/j.cstres.2026.100209_bib21","first-page":"161","article-title":"Induction and intracellular localization of 90-kilodalton heat-shock protein in rat kidneys with acute gentamicin nephropathy","volume":"72","author":"Ohtani","year":"1995","journal-title":"Lab Invest"},{"key":"10.1016\/j.cstres.2026.100209_bib22","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/492838","article-title":"Urinary \u03b22-microglobulin is a good indicator of proximal tubule injury: a correlative study with renal biopsies","volume":"2014","author":"Zeng","year":"2014","journal-title":"J Biomark"},{"key":"10.1016\/j.cstres.2026.100209_bib23","first-page":"444","article-title":"Revisiting the role of NAG across the continuum of kidney disease","volume":"10","author":"Novak","year":"2023","journal-title":"Bioeng (Basel)"},{"key":"10.1016\/j.cstres.2026.100209_bib24","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.ajt.2023.10.016","article-title":"The Banff 2022 kidney meeting report: reappraisal of microvascular inflammation and the role of biopsy-based transcript diagnostics","volume":"24","author":"Naesens","year":"2024","journal-title":"Am J Transpl"}],"container-title":["Cell Stress and Chaperones"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355814526000672?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1355814526000672?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:38:36Z","timestamp":1788590316000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1355814526000672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S1355814526000672"],"URL":"https:\/\/doi.org\/10.1016\/j.cstres.2026.100209","relation":{},"ISSN":["1355-8145"],"issn-type":[{"value":"1355-8145","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urinary HSP90 as a non-invasive biomarker of active tubular injury in kidney transplant recipients: A multicenter prospective study","name":"articletitle","label":"Article Title"},{"value":"Cell Stress and Chaperones","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cstres.2026.100209","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of Cell Stress Society International.","name":"copyright","label":"Copyright"}],"article-number":"100209"}}