{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:10:50Z","timestamp":1780920650676,"version":"3.54.1"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":110,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Treatment and Research Communications"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.ctarc.2026.101226","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T23:55:50Z","timestamp":1777334150000},"page":"101226","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Multimodal liquid biopsy surveillance after pancreatectomy for pancreatic ductal adenocarcinoma: evidence and a confirmation\u2011gated, trial\u2011ready framework"],"prefix":"10.1016","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0259-5807","authenticated-orcid":false,"given":"Lei","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9792-7747","authenticated-orcid":false,"given":"Zhen","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.ctarc.2026.101226_bib0001","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1038\/s41591-019-0652-7","article-title":"High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants","volume":"25","author":"Razavi","year":"2019","journal-title":"Nat. Med."},{"issue":"18","key":"10.1016\/j.ctarc.2026.101226_bib0002","doi-asserted-by":"crossref","first-page":"4437","DOI":"10.1158\/1078-0432.CCR-18-0143","article-title":"False-positive plasma genotyping due to clonal hematopoiesis","volume":"24","author":"Hu","year":"2018","journal-title":"Clin. Cancer Res."},{"issue":"11","key":"10.1016\/j.ctarc.2026.101226_bib0003","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.annonc.2023.08.009","article-title":"Pancreatic cancer: ESMO clinical practice guideline for diagnosis, treatment and follow-up","volume":"34","author":"Conroy","year":"2023","journal-title":"Ann. Oncol."},{"issue":"2","key":"10.1016\/j.ctarc.2026.101226_bib0004","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12404","article-title":"Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches","volume":"13","author":"Welsh","year":"2024","journal-title":"J. ExtraCell Vesicles."},{"issue":"8","key":"10.1016\/j.ctarc.2026.101226_bib0005","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.annonc.2022.05.520","article-title":"ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO precision medicine working group","volume":"33","author":"Pascual","year":"2022","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.ctarc.2026.101226_bib0006","series-title":"ISO 20186-3:2019 Molecular in Vitro Diagnostic Examinations \u2014 Specifications for Pre-Examination Processes For Venous Whole Blood \u2014 Part 3: Isolated circulating Cell Free DNA from Plasma","first-page":"17","year":"2019"},{"issue":"16","key":"10.1016\/j.ctarc.2026.101226_bib0007","doi-asserted-by":"crossref","first-page":"4973","DOI":"10.1158\/1078-0432.CCR-19-0197","article-title":"Circulating tumor DNA as a clinical test in resected pancreatic cancer","volume":"25","author":"Groot","year":"2019","journal-title":"Clin. Cancer Res."},{"issue":"9","key":"10.1016\/j.ctarc.2026.101226_bib0008","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1093\/annonc\/mdz200","article-title":"Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer","volume":"30","author":"Lee","year":"2019","journal-title":"Ann. Oncol."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101226_bib0009","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1158\/1078-0432.CCR-16-0806","article-title":"Plasma circulating tumor DNA in pancreatic cancer patients is a prognostic marker","volume":"23","author":"Pietrasz","year":"2017","journal-title":"Clin. Cancer Res."},{"issue":"7559","key":"10.1016\/j.ctarc.2026.101226_bib0010","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nature14581","article-title":"Glypican-1 identifies cancer exosomes and detects early pancreatic cancer","volume":"523","author":"Melo","year":"2015","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.ctarc.2026.101226_bib0011","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/annonc\/mdx004","article-title":"High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients","volume":"28","author":"Allenson","year":"2017","journal-title":"Ann. Oncol."},{"issue":"13","key":"10.1016\/j.ctarc.2026.101226_bib0012","doi-asserted-by":"crossref","first-page":"3248","DOI":"10.1158\/1078-0432.CCR-19-3313","article-title":"A multianalyte panel consisting of extracellular vesicle miRNAs and mRNAs, cfDNA, and CA19-9 shows utility for diagnosis and staging of pancreatic ductal adenocarcinoma","volume":"26","author":"Yang","year":"2020","journal-title":"Clin. Cancer Res."},{"issue":"16","key":"10.1016\/j.ctarc.2026.101226_bib0013","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abm3453","article-title":"Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer","volume":"8","author":"Ferguson","year":"2022","journal-title":"Sci. Adv."},{"issue":"3","key":"10.1016\/j.ctarc.2026.101226_bib0014","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/SLA.0000000000002925","article-title":"Circulating tumor cells dynamics in pancreatic adenocarcinoma correlate with disease status: results of the prospective CLUSTER study","volume":"268","author":"Gemenetzis","year":"2018","journal-title":"Ann. Surg."},{"issue":"4","key":"10.1016\/j.ctarc.2026.101226_bib0015","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1245\/s10434-017-6290-8","article-title":"Circulating tumor cells predict occult metastatic disease and prognosis in pancreatic cancer","volume":"25","author":"Court","year":"2018","journal-title":"Ann. Surg. Oncol."},{"key":"10.1016\/j.ctarc.2026.101226_bib0016","article-title":"Portal versus peripheral circulating tumor cells as prognostic biomarkers in patients with stage I-III pancreatic ductal adenocarcinoma","author":"Prasoppokakorn","year":"2025","journal-title":"Endoscopy"},{"issue":"5","key":"10.1016\/j.ctarc.2026.101226_bib0017","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/nbt.3520","article-title":"Integrated digital error suppression for improved detection of circulating tumor DNA","volume":"34","author":"Newman","year":"2016","journal-title":"Nat. Biotechnol."},{"issue":"11","key":"10.1016\/j.ctarc.2026.101226_bib0018","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1038\/nprot.2014.170","article-title":"Detecting ultralow-frequency mutations by Duplex sequencing","volume":"9","author":"Kennedy","year":"2014","journal-title":"Nat. Protoc."},{"issue":"16","key":"10.1016\/j.ctarc.2026.101226_bib0019","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1200\/JCO.2017.76.8671","article-title":"Circulating tumor DNA analysis in patients with cancer: American society of clinical oncology and college of American pathologists joint review","volume":"36","author":"Merker","year":"2018","journal-title":"J. Clin. Oncol."},{"issue":"8","key":"10.1016\/j.ctarc.2026.101226_bib0020","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/clinchem\/hvaa125","article-title":"The Digital MIQE Guidelines update: minimum information for publication of quantitative digital PCR experiments for 2020","volume":"66","author":"Huggett","year":"2020","journal-title":"Clin. Chem."},{"issue":"2","key":"10.1016\/j.ctarc.2026.101226_bib0021","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/s41568-022-00536-4","article-title":"Biology, vulnerabilities and clinical applications of circulating tumour cells","volume":"23","author":"Ring","year":"2023","journal-title":"Nat. Rev. Cancer"},{"issue":"7","key":"10.1016\/j.ctarc.2026.101226_bib0022","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/s41571-019-0187-3","article-title":"Liquid biopsy and minimal residual disease \u2014 latest advances and implications for cure","volume":"16","author":"Pantel","year":"2019","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101226_bib0023","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1186\/s12943-023-01880-1","article-title":"Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis","volume":"22","author":"Stoecklein","year":"2023","journal-title":"Mol. Cancer"},{"issue":"6","key":"10.1016\/j.ctarc.2026.101226_bib0024","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1016\/j.celrep.2014.08.029","article-title":"Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells","volume":"8","author":"Ting","year":"2014","journal-title":"Cell Rep."},{"issue":"10","key":"10.1016\/j.ctarc.2026.101226_bib0025","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1039\/C4LC00041B","article-title":"Microfluidic immunocapture of circulating pancreatic cells using parallel EpCAM and MUC1 capture: characterization, optimization and downstream analysis","volume":"14","author":"Thege","year":"2014","journal-title":"Lab. Chip."},{"issue":"179","key":"10.1016\/j.ctarc.2026.101226_bib0026","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3005616","article-title":"Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells","volume":"5","author":"Ozkumur","year":"2013","journal-title":"Sci. Transl. Med."},{"issue":"3","key":"10.1016\/j.ctarc.2026.101226_bib0027","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1038\/nprot.2014.044","article-title":"Microfluidic, marker-free isolation of circulating tumor cells from blood samples","volume":"9","author":"Karabacak","year":"2014","journal-title":"Nat. Protoc."},{"issue":"1\u20132","key":"10.1016\/j.ctarc.2026.101226_bib0028","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.cell.2018.11.046","article-title":"Circulating tumor cell clustering shapes DNA methylation to enable metastasis seeding","volume":"176","author":"Gkountela","year":"2019","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.ctarc.2026.101226_bib0029","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1373\/clinchem.2019.310854","article-title":"Toward standardization of preanalytical procedures for cell-free DNA profiling","volume":"66","author":"Tsui","year":"2020","journal-title":"Clin. Chem."},{"issue":"7761","key":"10.1016\/j.ctarc.2026.101226_bib0030","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/s41586-019-1272-6","article-title":"Genome-wide cell-free DNA fragmentation in patients with cancer","volume":"570","author":"Cristiano","year":"2019","journal-title":"Nature"},{"issue":"466","key":"10.1016\/j.ctarc.2026.101226_bib0031","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aat4921","article-title":"Enhanced detection of circulating tumor DNA by fragment size analysis","volume":"10","author":"Mouliere","year":"2018","journal-title":"Sci. Transl. Med."},{"issue":"22","key":"10.1016\/j.ctarc.2026.101226_bib0032","doi-asserted-by":"crossref","first-page":"8604","DOI":"10.1021\/ac202028g","article-title":"High-throughput droplet digital PCR system for absolute quantitation of DNA copy number","volume":"83","author":"Hindson","year":"2011","journal-title":"Anal. Chem."},{"issue":"7732","key":"10.1016\/j.ctarc.2026.101226_bib0033","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/s41586-018-0703-0","article-title":"Sensitive tumour detection and classification using plasma cell-free DNA methylomes","volume":"563","author":"Shen","year":"2018","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.ctarc.2026.101226_bib0034","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ccell.2017.07.007","article-title":"Integrated genomic characterization of pancreatic ductal adenocarcinoma","volume":"32","year":"2017","journal-title":"Cancer Cell."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101226_bib0035","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1093\/clinchem\/hvad189","article-title":"Towards the clinical implementation of extracellular vesicle-based biomarker assays for cancer","volume":"70","author":"Van Dorpe","year":"2024","journal-title":"Clin. Chem."},{"issue":"3","key":"10.1016\/j.ctarc.2026.101226_bib0036","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/nmeth.4185","article-title":"EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research","volume":"14","author":"Van Deun","year":"2017","journal-title":"Nat. Methods"},{"issue":"6761","key":"10.1016\/j.ctarc.2026.101226_bib0037","doi-asserted-by":"crossref","DOI":"10.1126\/science.adp3971","article-title":"Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA","volume":"389","author":"Murphy","year":"2025","journal-title":"Science"},{"issue":"6761","key":"10.1016\/j.ctarc.2026.101226_bib0038","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1126\/science.aea0555","article-title":"The ins and outs of circulating DNA","volume":"389","author":"Tsui","year":"2025","journal-title":"Science"},{"issue":"10485","key":"10.1016\/j.ctarc.2026.101226_bib0039","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1016\/S0140-6736(25)00261-2","article-title":"Pancreatic cancer","volume":"405","author":"Stoop","year":"2025","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ctarc.2026.101226_bib0040","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1186\/s12943-023-01870-3","article-title":"Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation","volume":"22","author":"Wang","year":"2023","journal-title":"Mol. Cancer"},{"issue":"2","key":"10.1016\/j.ctarc.2026.101226_bib0041","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/s41580-018-0080-4","article-title":"New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer","volume":"20","author":"Dongre","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"12","key":"10.1016\/j.ctarc.2026.101226_bib0042","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1158\/1078-0432.CCR-18-0120","article-title":"Improved risk stratification by circulating tumor cell counts in pancreatic cancer","volume":"24","author":"Effenberger","year":"2018","journal-title":"Clin. Cancer Res."},{"issue":"6","key":"10.1016\/j.ctarc.2026.101226_bib0043","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1097\/SLA.0000000000001600","article-title":"Circulating tumor cell phenotype predicts recurrence and survival in pancreatic adenocarcinoma","volume":"264","author":"Poruk","year":"2016","journal-title":"Ann. Surg."},{"issue":"11","key":"10.1016\/j.ctarc.2026.101226_bib0044","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1158\/1078-0432.CCR-16-1467","article-title":"Circulating tumor cells expressing markers of tumor-initiating cells predict poor survival and cancer recurrence in patients with pancreatic ductal adenocarcinoma","volume":"23","author":"Poruk","year":"2017","journal-title":"Clin. Cancer Res."},{"issue":"8","key":"10.1016\/j.ctarc.2026.101226_bib0045","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1055\/a-2535-7440","article-title":"Portal versus peripheral circulating tumor cells as prognostic biomarkers in patients with stage I-III pancreatic ductal adenocarcinoma","volume":"57","author":"Prasoppokakorn","year":"2025","journal-title":"Endoscopy"},{"issue":"9","key":"10.1016\/j.ctarc.2026.101226_bib0046","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/nm.1789","article-title":"Circulating mutant DNA to assess tumor dynamics","volume":"14","author":"Diehl","year":"2008","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101226_bib0047","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/bjc.2016.175","article-title":"Prognostic value of circulating tumour DNA in patients undergoing curative resection for pancreatic cancer","volume":"115","author":"Hadano","year":"2016","journal-title":"Br. J. Cancer"},{"issue":"391","key":"10.1016\/j.ctarc.2026.101226_bib0048","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aal3226","article-title":"Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy","volume":"9","author":"Yang","year":"2017","journal-title":"Sci. Transl. Med."},{"issue":"7","key":"10.1016\/j.ctarc.2026.101226_bib0049","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.1074\/jbc.C113.532267","article-title":"Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer","volume":"289","author":"Kahlert","year":"2014","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.ctarc.2026.101226_bib0050","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/ncb3169","article-title":"Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver","volume":"17","author":"Costa-Silva","year":"2015","journal-title":"Nat. Cell Biol."},{"issue":"3","key":"10.1016\/j.ctarc.2026.101226_bib0051","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1136\/gutjnl-2019-318860","article-title":"Plasma extracellular vesicle long RNA profiling identifies a diagnostic signature for the detection of pancreatic ductal adenocarcinoma","volume":"69","author":"Yu","year":"2020","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.ctarc.2026.101226_bib0052","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1053\/j.gastro.2018.09.022","article-title":"Circulating nucleic acids are associated with outcomes of patients with pancreatic cancer","volume":"156","author":"Bernard","year":"2019","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.ctarc.2026.101226_bib0053","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1053\/j.gastro.2015.08.050","article-title":"Acquisition of portal venous circulating tumor cells from patients with pancreaticobiliary cancers by endoscopic ultrasound","volume":"149","author":"Catenacci","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ctarc.2026.101226_bib0054","unstructured":"Network, N.C.C., NCCN Clinical Practice Guidelines in Oncology: pancreatic adenocarcinoma. Version 2.2025. 2025."},{"issue":"7969","key":"10.1016\/j.ctarc.2026.101226_bib0055","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/s41586-023-06225-y","article-title":"Practical recommendations for using ctDNA in clinical decision making","volume":"619","author":"Cohen","year":"2023","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.ctarc.2026.101226_bib0056","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41576-018-0071-5","article-title":"Current and future perspectives of liquid biopsies in genomics-driven oncology","volume":"20","author":"Heitzer","year":"2019","journal-title":"Nat. Rev. Genet."},{"issue":"35","key":"10.1016\/j.ctarc.2026.101226_bib0057","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.18.00328","article-title":"Identification of incidental germline mutations in patients with advanced solid tumors who underwent cell-free circulating tumor DNA sequencing","volume":"36","author":"Slavin","year":"2018","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.ctarc.2026.101226_bib0058","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2021-067975","article-title":"Consolidated health economic evaluation reporting standards 2022 (CHEERS 2022) statement: updated reporting guidance for health economic evaluations","volume":"376","author":"Husereau","year":"2022","journal-title":"BMJ"}],"container-title":["Cancer Treatment and Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468294226001371?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468294226001371?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T11:41:09Z","timestamp":1780918869000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468294226001371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":58,"alternative-id":["S2468294226001371"],"URL":"https:\/\/doi.org\/10.1016\/j.ctarc.2026.101226","relation":{},"ISSN":["2468-2942"],"issn-type":[{"value":"2468-2942","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multimodal liquid biopsy surveillance after pancreatectomy for pancreatic ductal adenocarcinoma: evidence and a confirmation\u2011gated, trial\u2011ready framework","name":"articletitle","label":"Article Title"},{"value":"Cancer Treatment and Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctarc.2026.101226","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101226"}}