{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T12:12:10Z","timestamp":1780920730134,"version":"3.54.1"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":117,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005317","name":"Kermanshah University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005317","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Treatment and Research Communications"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.ctarc.2026.101234","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:21:58Z","timestamp":1777602118000},"page":"101234","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Colorectal cancer trends in Iran: An age-period-cohort analysis of incidence and mortality and trends in key risk factors"],"prefix":"10.1016","volume":"47","author":[{"given":"Rasoul","family":"Gholamiveis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Heydarpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7033-6755","authenticated-orcid":false,"given":"Mehdi","family":"Moradinazar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ctarc.2026.101234_bib0001","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1053\/j.gastro.2019.10.007","article-title":"International perspective on the burden of colorectal cancer and public health effects","volume":"158","author":"Rabeneck","year":"2020","journal-title":"Gastroenterology"},{"issue":"12","key":"10.1016\/j.ctarc.2026.101234_bib0002","article-title":"General versus interventional Gastroenterologists: a comparative analysis of follow-up outcomes after endoscopic mucosal resection of colorectal polyps","volume":"16","author":"Madi","year":"2024","journal-title":"Cureus"},{"issue":"3","key":"10.1016\/j.ctarc.2026.101234_bib0003","first-page":"209","article-title":"Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101234_bib0004","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1186\/s12889-024-18027-6","article-title":"Burden of colorectal cancer and its risk factors in the North Africa and Middle East (NAME) region, 1990\u20132019: a systematic analysis of the global burden of disease study","volume":"24","author":"Haghighatdoost","year":"2024","journal-title":"BMC Public Health"},{"issue":"3","key":"10.1016\/j.ctarc.2026.101234_bib0005","first-page":"309","article-title":"Incidence and mortality of various cancers in Iran and compare to other countries: a review article","volume":"47","author":"Farhood","year":"2018","journal-title":"Iran. J. Public Health"},{"key":"10.1016\/j.ctarc.2026.101234_bib0006","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2015\/643020","article-title":"Colorectal cancer in Iran: molecular epidemiology and screening strategies","volume":"2015","author":"Dolatkhah","year":"2015","journal-title":"J. Cancer Epidemiol."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101234_bib0007","doi-asserted-by":"crossref","first-page":"72","DOI":"10.15171\/hpp.2015.009","article-title":"Iranian dietary patterns and risk of colorectal cancer","volume":"5","author":"Azizi","year":"2015","journal-title":"Health Promot. Perspect."},{"key":"10.1016\/j.ctarc.2026.101234_bib0008","first-page":"65","article-title":"Incidence of colorectal cancer in Iran: a systematic review and meta-analysis","volume":"29","author":"Rahimi","year":"2024","journal-title":"J. Res. Med. Sci."},{"key":"10.1016\/j.ctarc.2026.101234_bib0009","article-title":"Distinct time trends in colorectal cancer incidence in countries with SDI levels from 1990 to 2019: an age-period-cohort analysis for the Global Burden of Disease 2019 study","volume":"12","author":"Zhang","year":"2024","journal-title":"Front. Public Health"},{"issue":"2","key":"10.1016\/j.ctarc.2026.101234_bib0010","doi-asserted-by":"crossref","first-page":"526","DOI":"10.4143\/crt.2016.316","article-title":"Trends and age-period-cohort effects on the incidence and mortality rate of cervical cancer in Korea","volume":"49","author":"Moon","year":"2017","journal-title":"Cancer Res. Treat."},{"key":"10.1016\/j.ctarc.2026.101234_bib0011","doi-asserted-by":"crossref","DOI":"10.3389\/frph.2024.1501675","article-title":"Trends and projections of the burden of disease for male infertility in China from 1990 to 2021: an analysis from the Global Burden of Disease 2021 study","volume":"6","author":"Xu","year":"2024","journal-title":"Front. Reprod. Health"},{"issue":"5","key":"10.1016\/j.ctarc.2026.101234_bib0012","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1111\/add.15696","article-title":"Understanding long-term trends in smoking in England, 1972-2019: an age-period-cohort approach","volume":"117","author":"Opazo Breton","year":"2022","journal-title":"Addiction"},{"key":"10.1016\/j.ctarc.2026.101234_bib0013","first-page":"738","article-title":"Colorectal cancer in Iran: epidemiology and morphology trends","volume":"15","author":"Rafiemanesh","year":"2016","journal-title":"EXCLI J."},{"key":"10.1016\/j.ctarc.2026.101234_bib0014","article-title":"Long-term trends in the burden of multiple myeloma in China: a joinpoint regression and age-period-cohort analysis based on GBD 2021","volume":"13","author":"Zhang","year":"2025","journal-title":"Front. Public Health"},{"issue":"5","key":"10.1016\/j.ctarc.2026.101234_bib0015","first-page":"384","article-title":"The outcomes of health care process in Iran's rural society","volume":"18","author":"Eskandari","year":"2013","journal-title":"Iran. J. Nurs. Midwifery Res."},{"key":"10.1016\/j.ctarc.2026.101234_bib0016","unstructured":"(IHME) IfHMaE. Global Burden of Disease 2022 2022 [Available from: https:\/\/vizhub.healthdata.org\/gbd-results\/."},{"issue":"9063","key":"10.1016\/j.ctarc.2026.101234_bib0017","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/S0140-6736(96)07495-8","article-title":"Global mortality, disability, and the contribution of risk factors: global burden of disease study","volume":"349","author":"Murray","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.ctarc.2026.101234_bib0018","unstructured":"Carstensen B., Plummer M., Laara E., Hills M., Carstensen M.B. Package \u2018Epi\u2019. A package for statistical analysis in epidemiology CRAN. 2013."},{"key":"10.1016\/j.ctarc.2026.101234_bib0019","doi-asserted-by":"crossref","unstructured":"Keiding N. L exis Diagram. Encyclopedia of Biostatistics 2005;4.","DOI":"10.1002\/0471667196.ess1085.pub2"},{"issue":"3","key":"10.1016\/j.ctarc.2026.101234_bib0020","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z","article-title":"Permutation tests for joinpoint regression with applications to cancer rates","volume":"19","author":"Kim","year":"2000","journal-title":"Stat. Med."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101234_bib0021","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s12943-024-02020-z","article-title":"Aging and cancer","volume":"23","author":"Mont\u00e9gut","year":"2024","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.ctarc.2026.101234_bib0022","article-title":"Association between accelerated biological aging and colorectal cancer: a cross-sectional study","volume":"12","author":"Wang","year":"2025","journal-title":"Front. Med."},{"key":"10.1016\/j.ctarc.2026.101234_bib0024","first-page":"21","article-title":"Evaluation of pilot colorectal cancer screening programs in Iran","volume":"12","author":"Mirzaei","year":"2016","journal-title":"Iran. J. Epidemiol."},{"issue":"1","key":"10.1016\/j.ctarc.2026.101234_bib0025","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1186\/s12889-024-18027-6","article-title":"Burden of colorectal cancer and its risk factors in the North Africa and Middle East (NAME) region, 1990-2019: a systematic analysis of the global burden of disease study","volume":"24","author":"Haghighatdoost","year":"2024","journal-title":"BMC Public Health"},{"key":"10.1016\/j.ctarc.2026.101234_bib0026","unstructured":"Organization WH. Obesity and overweight 2021 [Available from: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight."},{"issue":"9785","key":"10.1016\/j.ctarc.2026.101234_bib0027","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(11)60679-X","article-title":"National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2\u00b77 million participants","volume":"378","author":"Danaei","year":"2011","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.ctarc.2026.101234_bib0028","doi-asserted-by":"crossref","first-page":"e1381","DOI":"10.1016\/S2214-109X(22)00361-8","article-title":"Worldwide physical activity trends since COVID-19 onset","volume":"10","author":"Tison","year":"2022","journal-title":"Lancet Glob. Health"},{"issue":"9","key":"10.1016\/j.ctarc.2026.101234_bib0029","doi-asserted-by":"crossref","first-page":"472","DOI":"10.34172\/aim.2023.72","article-title":"National and provincial prevalence of cigarette smoking in Iran; a systematic analysis of 12 years of STEPS experience","volume":"26","author":"Shahmohamadi","year":"2023","journal-title":"Arch. Iran. Med."},{"issue":"6","key":"10.1016\/j.ctarc.2026.101234_bib0030","doi-asserted-by":"crossref","first-page":"988","DOI":"10.4149\/neo_2019_190131N92","article-title":"Survival rate of colon and rectum cancer in Iran: a systematic review and meta-analysis","volume":"66","author":"Panahi","year":"2019","journal-title":"Neoplasma"}],"container-title":["Cancer Treatment and Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468294226001450?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468294226001450?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T11:51:00Z","timestamp":1780919460000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468294226001450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":29,"alternative-id":["S2468294226001450"],"URL":"https:\/\/doi.org\/10.1016\/j.ctarc.2026.101234","relation":{},"ISSN":["2468-2942"],"issn-type":[{"value":"2468-2942","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Colorectal cancer trends in Iran: An age-period-cohort analysis of incidence and mortality and trends in key risk factors","name":"articletitle","label":"Article Title"},{"value":"Cancer Treatment and Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctarc.2026.101234","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101234"}}